Granular transformation of Sertoli cells in testicular disorders.

abstract：:All cases of primary breast carcinoma seen at the George Washington University Medical Center between 1971 and 1975 and between 1981 and 1986 were reviewed, and examples of pure and mixed infiltrating cribriform carcinoma (ICC) were identified. The relative frequency of ICC did not change significantly from the earlie...

journal_title：Human pathology

authors： Venable JG,Schwartz AM,Silverberg SG

更新日期：1990-03-01 00:00:00

abstract：:Ciliated metaplasia (CM) of gastric mucosa is common in Japanese individuals but rare in whites. We studied 36 consecutive gastrectomies from Chinese individuals for the presence of CM. The gastrectomies were performed for adenocarcinoma (n = 22), benign ulcer (n = 13), and malignant lymphoma (n = 1). Ciliated metapla...

journal_title：Human pathology

authors： Chan WY,Hui PK,Leung KM,Robertson CS,Chung SC

更新日期：1993-10-01 00:00:00

abstract：:Patients with small cell lung carcinoma (SCLC) rarely demonstrate long-term survival. We previously reported that gene expression profiling identified a subset of SCLC with good prognosis in surgical cases. To find an easier way to routinely identify SCLC belonging to this subset, we conducted the present study with a...

journal_title：Human pathology

authors： Hamanaka W,Motoi N,Ishikawa S,Ushijima M,Inamura K,Hatano S,Uehara H,Okumura S,Nakagawa K,Nishio M,Horai T,Aburatani H,Matsuura M,Iwasaki A,Ishikawa Y

更新日期：2014-05-01 00:00:00

abstract：:CD34 has been widely used for the assessment of sinusoid-like neoangiogenesis in hepatocellular carcinoma (HCC). Recently, it was demonstrated that CD34-positive cells isolated from human peripheral blood differentiate into endothelial cells and contribute to neoangiogenesis in adults. We investigated the localization...

journal_title：Human pathology

authors： Ohmori S,Shiraki K,Sugimoto K,Sakai T,Fujikawa K,Wagayama H,Takase K,Nakano T

更新日期：2001-12-01 00:00:00

abstract：:Plasmablastic lymphoma (PBL) of the oral cavity is classified as one subtype of diffuse large B-cell lymphoma that is most commonly seen in patients with human immunodeficiency virus infection. We report a rare case of PBL in the anal canal of a 33-year-old man with human immunodeficiency virus infection. The lymphoma...

journal_title：Human pathology

authors： Tavora F,Gonzalez-Cuyar LF,Sun CC,Burke A,Zhao XF

更新日期：2006-09-01 00:00:00

abstract：:Hyalinizing clear cell carcinoma (HCCC) has only been described in salivary glands of the head and neck. We report a 38-year-old man with a 2.6-cm lung tumor that was growing in a peribronchial location and had morphologic features of HCCC. The tumor cells expressed cytokeratin 7 and keratin AE1/AE3, and the vast majo...

journal_title：Human pathology

authors： García JJ,Jin L,Jackson SB,Larsen BT,Lewis JE,Sukov WR,Roden AC

更新日期：2015-03-01 00:00:00

abstract：:Malignant mesotheliomas are highly aggressive tumors that develop most frequently in the pleura of patients chronically exposed to asbestos. The distinction between malignant mesotheliomas and tumors of epithelial origin, particularly peripheral lung adenocarcinoma, can be difficult despite the use of immunocytochemic...

journal_title：Human pathology

authors： Peralta Soler A,Knudsen KA,Jaurand MC,Johnson KR,Wheelock MJ,Klein-Szanto AJ,Salazar H

更新日期：1995-12-01 00:00:00

abstract：:Bag-1 is an antiapoptotic protein with its altered expression and localization in malignancies. To clarify the role of Bag-1 in gastric carcinogenesis, its expression was examined by immunohistochemistry and in situ hybridization on a tissue microarray containing gastric carcinomas, adjacent nonneoplastic mucosa (NNM)...

journal_title：Human pathology

authors： Zheng HC,Xu XY,Xing YN,Wei ZL,Takahashi H,Masuda S,Takano Y

更新日期：2010-05-01 00:00:00

abstract：:CDX2 is a sensitive and specific marker of intestinal differentiation. It is routinely used in surgical pathology, as its expression within a tumor favors an origin within the gastrointestinal tract. We had anecdotally encountered occasional hepatocellular carcinomas (HCCs) that were CDX2 positive. CDX2 expression in ...

journal_title：Human pathology

authors： Shah SS,Wu TT,Torbenson MS,Chandan VS

更新日期：2017-06-01 00:00:00

abstract：:Telomerase is a ribonucleoprotein enzyme associated with cellular immortality and has been detected in the vast majority of adult tumors. Wilms tumor is a histologically diverse embryonal malignancy of childhood, and the histological features of Wilms tumor and its precursor lesion, the nephrogenic rest, recapitulate ...

journal_title：Human pathology

authors： Yashima K,Maitra A,Timmons CF,Rogers BB,Pinar H,Shay JW,Gazdar AF

更新日期：1998-05-01 00:00:00

abstract：:Hepatic artery thrombosis (HAT) following orthotopic liver transplantation (OLT) can cause hepatic parenchymal necrosis and ischemic cholangiopathy. This study investigates additional histologic features that may suggest HAT in post-OLT liver specimens. For 94 liver specimens (explanted allografts and biopsies) from p...

journal_title：Human pathology

authors： Lee M,Agostini-Vulaj D,Gonzalez RS

更新日期：2019-08-01 00:00:00

abstract：:Preeclampsia is a leading cause for maternal and perinatal mortality and morbidity. Microarray-based transcriptional profiling has been widely used for identifying genes responsible for preeclampsia. These studies deliver multiple pictures of gene signatures, implying the complicated pathophysiology. In the present wo...

journal_title：Human pathology

authors： Louwen F,Muschol-Steinmetz C,Friemel A,Kämpf AK,Töttel E,Reinhard J,Yuan J

更新日期：2014-06-01 00:00:00

abstract：:Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumor...

journal_title：Human pathology

authors： Zwick DL,Livingston K,Clapp L,Kosnik E,Yates A

更新日期：1989-04-01 00:00:00

abstract：:Kikuchi's histiocytic necrotizing lymphadenitis is a self-limited disorder that typically involves the cervical lymph nodes of young women. Although a viral etiology has been postulated, a definitive viral agent has not been identified. Recent reports have suggested that human herpesvirus 8 (HHV 8) or Epstein-Barr vir...

journal_title：Human pathology

authors： George TI,Jones CD,Zehnder JL,Warnke RA,Dorfman RF

更新日期：2003-02-01 00:00:00

abstract：:The striking differences in the histological features of gastric cancers in young and old adults have been thought to be related to differences in the biological behavior of these cancers. Recently, a new grading system (Goseki's classification) showed that the prognosis of the patient is particularly related to the m...

journal_title：Human pathology

authors： Sakamoto H,Yonezawa S,Utsunomiya T,Tanaka S,Kim YS,Sato E

更新日期：1997-09-01 00:00:00

abstract：:Basal cell hyperplasia (BCH) is an uncommon proliferative lesion of the prostate gland. We studied ten cases of BCH, one case of an unusual adenoid basal cell tumor (ABT), and one case of a prostatic adenoid cystic carcinoma (ACC), using a panel of antibodies to define the histogenesis of these lesions. Monoclonal ant...

journal_title：Human pathology

authors： Grignon DJ,Ro JY,Ordoñez NG,Ayala AG,Cleary KR

更新日期：1988-12-01 00:00:00

abstract：:Multicentric Castleman disease (MCD) is a systemic inflammatory disease potentially caused by an increase in the serum interleukin-6 (IL-6) level. Idiopathic MCD (iMCD) is histopathologically classified into three types: plasmacytic (PC), mixed, and hypervascular (hyperV) types. Recently, a unique clinical phenotype w...

journal_title：Human pathology

authors： Kurose N,Futatsuya C,Mizutani KI,Kumagai M,Shioya A,Guo X,Aikawa A,Nakada S,Fujimoto S,Kawabata H,Masaki Y,Takai K,Aoki S,Kojima M,Nakamura S,Yamada S

更新日期：2018-07-01 00:00:00

abstract：:Among 236 aortic valves surgically excised at the Mayo Clinic in 1990 (mean patient age, 66 years; age range, 10 to 92 years), 154 (65%) were stenotic, 58 (25%) were insufficient, and 24 (10%) were both stenotic and insufficient. Pure stenosis was related to calcification, and causes included degenerative (51%), bicus...

journal_title：Human pathology

authors： Dare AJ,Veinot JP,Edwards WD,Tazelaar HD,Schaff HV

更新日期：1993-12-01 00:00:00

abstract：:Neuronal intranuclear inclusion disease (NIID) is a progressive, usually fatal degenerative neurologic condition characterized by eosinophilic, intranuclear inclusions in neurons of the central and peripheral nervous system. We report a boy with onset of disease manifestations at age 3 and death at age 9, who showed c...

journal_title：Human pathology

authors： Oyer CE,Cortez S,O'Shea P,Popovic M

更新日期：1991-07-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection is usually reported in immunocompromised patients. This study reports 11 cases of HCMV infection of the gastrointestinal (GI) tract diagnosed in apparently immunocompetent hosts. The median age of the patients studied was 76 years, and the major presenting symptoms were diarrhea,...

journal_title：Human pathology

authors： Maiorana A,Baccarini P,Foroni M,Bellini N,Giusti F

更新日期：2003-12-01 00:00:00

abstract：:Alpha-methyl CoA racemase (AMACR), a new molecular marker for prostate cancer, has been recently reported to be one of the most highly expressed genes in papillary renal cell carcinomas (RCCs). We tested the diagnostic usefulness of AMACR antibody in a series of 110 renal tumors: 53 papillary RCCs (33 type 1, 20 type ...

journal_title：Human pathology

authors： Molinié V,Balaton A,Rotman S,Mansouri D,De Pinieux I,Homsi T,Guillou L

更新日期：2006-06-01 00:00:00

abstract：:High cathepsin D (cath-D) concentration in breast cancer cytosol is associated with increased risk of metastasis. To specify the relative contribution of the different cells types responsible for cath-D level in cytosol, we validated semiquantitative cath-D immunoperoxidase staining on formalin-fixed, paraffin-embedde...

journal_title：Human pathology

authors： Roger P,Montcourrier P,Maudelonde T,Brouillet JP,Pages A,Laffargue F,Rochefort H

更新日期：1994-09-01 00:00:00

abstract：:In the normal liver, the transforming growth factor beta (TGF-beta) signaling pathway plays an important role in inhibiting hepatocyte growth. This effect is mediated through Smad4 (or Dpc4), a tumor-suppressor gene that affects gene transcription and controls cell growth. A loss of Smad4 is associated with carcinoma ...

journal_title：Human pathology

authors： Torbenson M,Marinopoulos S,Dang DT,Choti M,Ashfaq R,Maitra A,Boitnott J,Wilentz RE

更新日期：2002-09-01 00:00:00

abstract：:Thromboangiitis obliterans (Buerger's disease) is an uncommon variety of occlusive peripheral vascular disease, occurring predominantly in young male tobacco smokers. The vascular lesion in the acute stage of thromboangiitis obliterans is distinctive and affects both the arteries and veins. Described here is an unusua...

journal_title：Human pathology

authors： Lie JT

更新日期：1987-04-01 00:00:00

abstract：:The expression of insulin-like growth factor 2 (IGF2) and insulin-like growth factor binding protein 2 (IGFBP2) in 11 cases of hepatoblastoma was studied by means of in situ mRNA hybridization using digoxigenin (DIG)-labeled riboprobes. The results showed that both IGF2 and IGFBP2 transcripts are present in hepatoblas...

journal_title：Human pathology

authors： Akmal SN,Yun K,MacLay J,Higami Y,Ikeda T

更新日期：1995-08-01 00:00:00

abstract：:The concept of minimal deviation melanoma is presented in diagrammatic form. In this approach, the precursors of melanoma are presented as having two dimensions and melanomas as having three dimensions. In turn, the relativity between dimensionalities and recommendations for treatment (as indirect correlates of progno...

journal_title：Human pathology

authors： Reed RJ

更新日期：1999-05-01 00:00:00

abstract：:DNA methyltransferase 1, 3a, and 3b affect DNA methylation, and it is thought that they play an important role in the malignant transformation of various cancers. The current study was designed to analyze DNA methyltransferase expression by immunohistochemistry in a series of 94 Tunisian sporadic breast carcinomas. Re...

journal_title：Human pathology

authors： Ben Gacem R,Hachana M,Ziadi S,Ben Abdelkarim S,Hidar S,Trimeche M

更新日期：2012-10-01 00:00:00

abstract：:Three cases of primary thymic neuroendocrine tumors characterized by prominent angiomatoid features that resembled a vascular neoplasm are presented. The patients were all men between 52 and 59 years of age who presented with chest pain and shortness of breath attributable to a large anterior mediastinal mass. The les...

journal_title：Human pathology

authors： Moran CA,Suster S

更新日期：1999-06-01 00:00:00

abstract：:A distinctive variant of basal cell adenoma called membranous basal cell adenoma is well recognized in salivary glands. It appears identical to cutaneous cylindroma, hence the synonym dermal analogue tumor. We present a case of a tumor involving the parotid gland that appeared identical to cutaneous spiradenoma. In ad...

journal_title：Human pathology

authors： Kazakov DV,Benkova K,Michal M,Vanecek T,Kacerovska D,Skalova A

更新日期：2009-10-01 00:00:00

abstract：:Heavy proteinuria after bone marrow transplantation (BMT) is rare. Pathology shows membranous glomerulonephritis (MGN) in most cases. After BMT, focal segmental glomerulosclerosis (FSGS) after resolution of MGN has not been reported. We describe a 13-year-old boy who had matched unrelated donor allogeneic BMT for rela...

journal_title：Human pathology

authors： Chan GS,Chim S,Fan YS,Chan KW

更新日期：2006-12-01 00:00:00