Dimensionalities: borderline and intermediate melanocytic neoplasia.

abstract：:The diagnosis of microscopic colitis (MC) relies on specific histopathological findings in colon biopsies. The number of biopsies needed to diagnose MC remains disputed. The aim of the study was to determine the number and site of biopsies necessary for the diagnosis and the effect of perpendicular orientation when em...

journal_title：Human pathology

authors： Kanstrup Fiehn AM,Heiberg Engel PJ,Lanzarotto F,Goudkade D,Landolfi S,Munck LK,Villanacci V

更新日期：2020-09-01 00:00:00

abstract：:We have experienced an autopsy case of a 20-year-old woman with bronchiolitis obliterans, pemphigus vulgaris, and Castleman's disease. The affected bronchioles showed almost the same histology as previously described. But, the number of the lesions seemed too small to cause her death of respiratory insufficiency. We a...

journal_title：Human pathology

authors： Saito K,Morita M,Enomoto K

更新日期：1997-11-01 00:00:00

abstract：:Micropapillary carcinoma is a histologic pattern, rather than an independent entity, that has an aggressive clinical behavior regardless of location. Histologically, it is characterized by papillary cell groups in clear spaces. The micropapillary pattern in the thyroid gland has not been studied until recently but und...

journal_title：Human pathology

authors： Lino-Silva LS,Domínguez-Malagón HR,Caro-Sánchez CH,Salcedo-Hernández RA

更新日期：2012-10-01 00:00:00

abstract：:Plakophilins (PKPs) are members of the armadillo multigene family. Armadillo-related proteins function in both cell adhesion and signal transduction, and also play a central role in tumorigenesis. Here we report the immunohistochemical localization of PKPs in 37 cases of human primary squamous cell carcinoma of the or...

journal_title：Human pathology

authors： Papagerakis S,Shabana AH,Depondt J,Gehanno P,Forest N

更新日期：2003-06-01 00:00:00

abstract：:The family of the poly(adenosine diphosphate-ribose) polymerase (PARP) proteins is directly involved in genomic stability, DNA repair, and apoptosis by DNA damage. In this study, we evaluated the role of PARP-1 in melanoma and its prognostic importance. We studied by immunohistochemistry and Western blot analysis PARP...

journal_title：Human pathology

authors： Staibano S,Pepe S,Lo Muzio L,Somma P,Mascolo M,Argenziano G,Scalvenzi M,Salvatore G,Fabbrocini G,Molea G,Bianco AR,Carlomagno C,De Rosa G

更新日期：2005-07-01 00:00:00

abstract：:Although the Revised European-American Lymphoma Classification does not utilize the term monocytoid B-cell Lymphoma, there are numerous reasons to support its use in classifying lymphomas of so-called marginal zone B-cell type that contain a distinct population of malignant monocytoid B-cells. In addition, there are o...

journal_title：Human pathology

authors： Nathwani BN,Hernandez AM,Deol I,Taylor CR

更新日期：1997-01-01 00:00:00

abstract：:Atypical mesothelial hyperplasia encountered in pleural fluid or in a pleural biopsy specimen raises the suspicion that one may be dealing with a diffuse malignant mesothelioma of the pleura. We studied eight cases with cytologic or histologic changes of mesothelial atypia thought to be suspicious for diffuse malignan...

journal_title：Human pathology

authors： Yokoi T,Mark EJ

更新日期：1991-07-01 00:00:00

abstract：:Primary dermal melanoma (PDM) is a rare variant of melanoma which simulates metastatic melanoma to the skin. Diagnosis of PDM cannot be established on histologic grounds alone but requires absence of evidence of melanoma elsewhere by clinical history and/or imaging studies. Despite this entity being clinically well do...

journal_title：Human pathology

authors： Shaigany S,Tessier-Cloutier B,Busam KJ,Horst BA

更新日期：2020-12-01 00:00:00

abstract：:Yes-associated protein, a downstream effector of the Hippo signaling pathway, has been linked to progression of non-small-cell lung carcinoma. The aim of this study was to investigate expression of Yes-associated protein in lung adenocarcinoma and squamous cell carcinoma. Associations of Yes-associated protein express...

journal_title：Human pathology

authors： Kim JM,Kang DW,Long LZ,Huang SM,Yeo MK,Yi ES,Kim KH

更新日期：2011-03-01 00:00:00

abstract：:Topoisomerases are ubiquitous nuclear enzymes that regulate DNA structure in eukaryotic cells. The role of topoisomerase IIIβ, the newest member of the topoisomerase family, in the clinical outcome of breast cancer is still poorly understood. This study aims to investigate the immunoexpression of topoisomerase IIIβ in...

journal_title：Human pathology

authors： Oliveira-Costa JP,Zanetti J,Oliveira LR,Soares FA,Ramalho LZ,Silva Ramalho F,Garcia SB,Ribeiro-Silva A

更新日期：2010-11-01 00:00:00

abstract：:Ultrastructural features of bilateral testicular biopsy materials, obtained from both tumor and nontumor areas of the testis of a 27-year-old man with congenital adrenal hyperplasia, revealed a number of pathologic changes. Germ cell hypoplasia and extratubular cellular hyperplasia were noticed in the nontumor portion...

journal_title：Human pathology

authors： Chakraborty J,Franco-Saenz R,Kropp K

更新日期：1983-02-01 00:00:00

abstract：:CD34 has been widely used for the assessment of sinusoid-like neoangiogenesis in hepatocellular carcinoma (HCC). Recently, it was demonstrated that CD34-positive cells isolated from human peripheral blood differentiate into endothelial cells and contribute to neoangiogenesis in adults. We investigated the localization...

journal_title：Human pathology

authors： Ohmori S,Shiraki K,Sugimoto K,Sakai T,Fujikawa K,Wagayama H,Takase K,Nakano T

更新日期：2001-12-01 00:00:00

abstract：:To examine the hypothesis that malpositions of cardiac ventricles could be explained by altered development of the interventricular septum, we studied hearts from the Johns Hopkins Hospital autopsy files with double inlet left ventricle (16 cases) or corrected transposition (nine cases). In double inlet left ventricle...

journal_title：Human pathology

authors： Hutchins GM,Meredith MA,Moore GW

更新日期：1981-03-01 00:00:00

abstract：:Astrocytoma grade IV (glioblastoma multiforme) is the most common and most malignant tumor of the central nervous system and is currently noncurable. Here, we have examined a population-based cohort of 47 patients with grade IV astrocytoma, who underwent tumor surgery at Sahlgrenska University Hospital in Sweden and w...

journal_title：Human pathology

authors： Skalli O,Wilhelmsson U,Orndahl C,Fekete B,Malmgren K,Rydenhag B,Pekny M

更新日期：2013-10-01 00:00:00

abstract：:Penile carcinoma (PC) is more frequent in underdeveloped countries, generally is diagnosed at an advanced stage when therapeutic options are restricted, and thus is associated with high morbidity/mortality rates. Recent studies have demonstrated clinical benefits with epidermal growth factor receptor (EGFR)-targeted t...

journal_title：Human pathology

authors： Silva Amancio AM,Cunha IW,Neves JI,Quetz JD,Carraro DM,Rocha RM,Zequi SC,Cubilla AL,da Fonseca FP,Lopes A,Cunha MD,Lima MV,Vassallo J,Guimarães GC,Soares FA

更新日期：2017-03-01 00:00:00

abstract：:Although adipophilin has been reported to be a sensitive marker for sebaceous carcinoma, others have noted its expression in squamous cell carcinoma and a variety of noncutaneous tumors, suggesting that lipid droplet accumulation is a frequent feature of neoplastic cells. We investigated the expression of adipophilin ...

journal_title：Human pathology

authors： Boussahmain C,Mochel MC,Hoang MP

更新日期：2013-09-01 00:00:00

abstract：:Organ transplant recipients have an increased tumor incidence owing to their immunocompromised state. The origin of such tumors, whether donor or recipient, will have a clinical impact on decision-making concerning immunosuppressive therapy, retransplantation, and for recipients of other organs from the same donors. W...

journal_title：Human pathology

authors： Baehner R,Magrane G,Balassanian R,Chang C,Millward C,Wakil AE,Osorio RW,Waldman FM

更新日期：2000-11-01 00:00:00

abstract：:Most histopathologic descriptions of influenza pneumonia are based on autopsy findings in fatal cases during epidemics and pandemics of influenza. We describe the histologic findings of influenza pneumonia observed in biopsy material derived from six sporadic cases of influenza (influenza A, four cases; influenza B, o...

journal_title：Human pathology

authors： Yeldandi AV,Colby TV

更新日期：1994-01-01 00:00:00

abstract：:Bfl-1, a member of the Bcl-2 gene family, blocks p53-mediated apoptosis and has oncogenic transforming activity. In normal tissues, the transcript of Bfl-1 is expressed abundantly in bone marrow and at a low level in several other tissues. In previous experiments, elevated expression of Bfl-1 was observed by Northern ...

journal_title：Human pathology

authors： Jung-Ha H,Kim D,Lee SB,Hong SI,Park SY,Huh J,Kim CW,Kim SS,Lee Y,Choi SS,Shin HS

更新日期：1998-07-01 00:00:00

abstract：:The benign epithelial neoplasm liver cell adenoma is rare, especially in childhood. We report 2 such cases, 1 of which was associated with Prader-Willi syndrome. Differential diagnosis of the liver cell adenomas on the basis of histopathologic findings proved difficult and was based on the absence of cellular and nucl...

journal_title：Human pathology

authors： Takayasu H,Motoi T,Kanamori Y,Kitano Y,Nakanishi H,Tange T,Nakagawara A,Hashizume K

更新日期：2002-08-01 00:00:00

abstract：:The synovium in two well-documented cases of alkaptonuric ochronosis was studied by transmission electron and light microscopy. A feature of alkaptonuria previously unreported in the English-language literature was the presence of phagocytosis of large collagen fibrils by synovial macrophages in both cases. The origin...

journal_title：Human pathology

authors： Gaines JJ Jr,Tom GD,Khankhanian N

更新日期：1987-11-01 00:00:00

abstract：:The cell of origin of parafollicular (monocytoid) B cell lymphoma (PBCL), splenic marginal zone lymphoma (SMZL), and hairy cell leukemia (HCL) is controversial. To better understand the relationship between these low-grade B-cell neoplasms, we analyzed the nucleotide sequences of the rearranged immunoglobulin heavy (I...

journal_title：Human pathology

authors： Miranda RN,Cousar JB,Hammer RD,Collins RD,Vnencak-Jones CL

更新日期：1999-03-01 00:00:00

abstract：:Intraprostatic spermatozoa (IS) have been demonstrated in only 2 articles in the literature reporting on postmortem prostates. Intraprostatic spermatozoa have not been previously described in radical prostatectomies. This is the first study that describes the presence of IS in radical prostatectomies with prostatic ca...

journal_title：Human pathology

authors： Chen X,Zhao J,Salim S,Garcia FU

更新日期：2006-03-01 00:00:00

abstract：:Neutrophilic dermatoses are an uncommon manifestation of lupus. We describe the clinical and histopathologic features of 14 patients with systemic lupus erythematosus (SLE) and neutrophilic dermatoses, 2 of whom had no prior history of SLE. Thirteen patients were female, ranging in age from 27 to 62 years (mean age, 4...

journal_title：Human pathology

authors： Larson AR,Granter SR

更新日期：2014-03-01 00:00:00

abstract：:We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet...

journal_title：Human pathology

authors： Iuga AC,Mull J,Batra R,Miller W

更新日期：2011-09-01 00:00:00

abstract：:Twenty-five cases of Crohn's disease confined to the appendix were reported in eight hospitals in Israel during a 15-year period. Review of the histologic slides confirmed the diagnosis in 22 cases. Re-evaluation of these 22 patients included physical examination and radiologic studies of the small and large bowel. Re...

journal_title：Human pathology

authors： Ariel I,Vinograd I,Hershlag A,Olsha O,Argov S,Klausner JM,Rabau MY,Freund U,Rosenmann E

更新日期：1986-11-01 00:00:00

abstract：:Mucosal addressin cell adhesion molecule 1, expressed on gut endothelial cells, in conjunction with integrin alpha(4)beta(7), expressed on lymphocytes, is critical in lymphocyte homing to the gut. The mucosal addressin cell adhesion molecule 1/integrin alpha(4)beta(7) pathway is involved in the pathogenesis of chronic...

journal_title：Human pathology

authors： Di Sabatino A,Rovedatti L,Rosado MM,Carsetti R,Corazza GR,MacDonald TT

更新日期：2009-05-01 00:00:00

abstract：:Most human papillomavirus-associated squamous intraepithelial lesions of the uterine cervix are flat; some have papillary architecture that shows a spectrum of differentiation from low-grade squamous intraepithelial lesions to high-grade squamous intraepithelial lesions. For this subset of lesions, there are few data ...

journal_title：Human pathology

authors： Liang CW,Lin MC,Hsiao CH,Lin YT,Kuo KT

更新日期：2010-03-01 00:00:00

abstract：:The number of opportunistic infections in the central nervous system (CNS) has been steadily increasing because of a rising number of immunocompromised patients. A rare form of CNS infection can be caused by Chaetomium species, one of the largest genera of saprophytic ascomycetes. The CNS lesions in the present case w...

journal_title：Human pathology

authors： Thomas C,Mileusnic D,Carey RB,Kampert M,Anderson D

更新日期：1999-07-01 00:00:00

abstract：:Kearns-Sayre syndrome (KSS) and Pearson's marrow-pancreas syndrome (PMPS) are rare disorders caused by the same molecular defect, one of several deletion mutations in mitochondrial DNA (mtDNA). KSS is an encephalomyopathy with ophthalmoplegia, retinal degeneration, ataxia, and endocrine abnormalities. PMPS is a disord...

journal_title：Human pathology

authors： Becher MW,Wills ML,Noll WW,Hurko O,Price DL

更新日期：1999-05-01 00:00:00