Abstract:
:We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet and ciliated cells completely replacing the testicular parenchyma. Immunohistochemical studies showed positivity for cytokeratin 20, carcinoembryonic antigen, and mucin 2, and negativity for cytokeratin 7, mucin 5AC, vimentin, thyroid transcription factor 1, Wilms' tumor 1, and cancer antigen 125. The current case shows a focal cyst-lining component with benign appearance. Imaging studies and colonoscopy showed no evidence of other suspicious lesions. This tumor resembles morphologically to an intestinal-type ovarian surface epithelial tumor.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Iuga AC,Mull J,Batra R,Miller Wdoi
10.1016/j.humpath.2010.11.021subject
Has Abstractpub_date
2011-09-01 00:00:00pages
1343-7issue
9eissn
0046-8177issn
1532-8392pii
S0046-8177(10)00447-8journal_volume
42pub_type
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