Endocardial fibroelastosis and myocardial calcification secondary to an anomalous right coronary artery arising from the pulmonary trunk.

abstract：:Recent studies demonstrated that protease-activated receptor-2 (PAR-2) correlates with tumor progression in various tissues. On the other hand, oxidative stress arising from endometriosis has been considered a cause of carcinogenesis in ovarian clear cell carcinoma (OCCC). We previously demonstrated that oxidative str...

journal_title：Human pathology

authors： Aman M,Ohishi Y,Imamura H,Shinozaki T,Yasutake N,Kato K,Oda Y

更新日期：2017-06-01 00:00:00

abstract：:In a large-scale analysis of gene expression in pancreatic cancer, we isolated the homologue of the mouse Rab20. The mouse protein was previously identified during a search for novel Rab proteins, a family of small GTP-binding proteins involved in the regulation of intracellular vesicular transport. The Rab20 protein ...

journal_title：Human pathology

authors： Amillet JM,Ferbus D,Real FX,Antony C,Muleris M,Gress TM,Goubin G

更新日期：2006-03-01 00:00:00

abstract：:Phyllodes tumors are rare but clinically important fibroepithelial tumors of the breast. Both epithelial and stromal components actively interact with each other to participate in phyllodes tumor development. Accumulated evidence suggests that the Wnt signaling pathway is important in this stromal-epithelial interacti...

journal_title：Human pathology

authors： Tsang JY,Mendoza P,Putti TC,Karim RZ,Scolyer RA,Lee CS,Pang AL,Tse GM

更新日期：2012-12-01 00:00:00

abstract：:Immunoglobulin G4-related sclerosing cholangitis is histologically characterized by the infiltration of immunoglobulin G4-positive plasma cells and sclerosing change. Moreover, several cases of carcinoma accompanied by immunoglobulin G4-positive cells in tissue and increased serum immunoglobulin G4 levels have been re...

journal_title：Human pathology

authors： Kimura Y,Harada K,Nakanuma Y

更新日期：2012-12-01 00:00:00

abstract：:Cribriform and/or papillary prostatic lesions observed on limited tissue, such as needle biopsy, can pose diagnostic dilemmas. One such area of difficulty is the distinction between papillary and/or cribriform prostatic high-grade prostatic intraepithelial neoplasia (HG-PIN) and ductal adenocarcinoma. Over 48 months, ...

journal_title：Human pathology

authors： Rioux-Leclercq N,Leray E,Patard JJ,Lobel B,Guillé F,Jouan F,Bellaud P,Epstein JI

更新日期：2005-05-01 00:00:00

abstract：:Alpha-methyl CoA racemase (AMACR), a new molecular marker for prostate cancer, has been recently reported to be one of the most highly expressed genes in papillary renal cell carcinomas (RCCs). We tested the diagnostic usefulness of AMACR antibody in a series of 110 renal tumors: 53 papillary RCCs (33 type 1, 20 type ...

journal_title：Human pathology

authors： Molinié V,Balaton A,Rotman S,Mansouri D,De Pinieux I,Homsi T,Guillou L

更新日期：2006-06-01 00:00:00

abstract：:Patients with retinoblastoma have an increased risk of developing second primary tumors. Only a few examples of sinonasal small cell neoplasms developing after radiation therapy for retinoblastoma have been reported. We report one such case that developed 18 years after treatment for retinoblastoma. Histologic examina...

journal_title：Human pathology

authors： Saw D,Chan JK,Jagirdar J,Greco MA,Lee M

更新日期：1992-08-01 00:00:00

abstract：:Epidermal growth factor receptor (EGF-r) expression and tumor cell proliferation rate have been proposed as potential prognostic parameters in renal cell carcinoma (RCC). In this study, immunohistochemical stains using antibodies to EGF-r and the cell proliferation marker Ki-67 (MIB-1) were used to study the relations...

journal_title：Human pathology

authors： Moch H,Sauter G,Buchholz N,Gasser TC,Bubendorf L,Waldman FM,Mihatsch MJ

更新日期：1997-11-01 00:00:00

abstract：:Although GATA binding protein 3, a zinc finger transcription factor and an estrogen receptor-regulated gene, has recently been suggested as a marker for urothelium, prognostic significance of GATA binding protein 3 expression in bladder tumor remains unclear. We immunohistochemically stained for GATA binding protein 3...

journal_title：Human pathology

authors： Miyamoto H,Izumi K,Yao JL,Li Y,Yang Q,McMahon LA,Gonzalez-Roibon N,Hicks DG,Tacha D,Netto GJ

更新日期：2012-11-01 00:00:00

abstract：:The clinicopathologic features and immunohistochemical profiles of 14 cases of a distinctive mesenchymal tumor that arises in the superficial lamina propria of the cervix and vagina and is histologically distinguishable from mesodermal (fibroepithelial) stromal polyp, including the cellular (pseudosarcomatous) variant...

journal_title：Human pathology

authors： Laskin WB,Fetsch JF,Tavassoli FA

更新日期：2001-07-01 00:00:00

abstract：:Increasing differentiation in the human endometrium is associated with an apparent decrease in intercellular contacts between endometrial stromal cells ...

journal_title：Human pathology

authors： Parmley TH,Roberts DK,Emsa NJ,Horbelt DV

更新日期：1990-10-01 00:00:00

abstract：:There is no consensus regarding biomarker testing on the ipsilateral breast carcinomas present in separate biopsies, irrespective of whether the biopsies are performed concurrently or consecutively. We aimed to investigate estrogen receptor (ER), progesterone receptor (PR) and HER2 concordance in ipsilateral concurren...

journal_title：Human pathology

authors： Singh K,Wang Y,Marketkar S,Kalife ET,Steinhoff MM

更新日期：2017-07-01 00:00:00

abstract：:Esophageal adenocarcinoma often presents at an advanced stage and has a dismal prognosis. Current prognostic markers have limited utility. ARID1A is implicated as a tumor suppressor gene in esophageal adenocarcinoma. Loss of ARID1A expression correlates with DNA mismatch repair (MMR) protein deficiency in other tumors...

journal_title：Human pathology

authors： Lowenthal BM,Nason KS,Pennathur A,Luketich JD,Pai RK,Davison JM,Ma C

更新日期：2019-12-01 00:00:00

abstract：:Nuclear pore complexes (NPCs) are elaborate macromolecular structures that regulate the bidirectional nucleocytoplasmic traffic system. In vertebrate cells, NPCs include a family of 50 to 100 proteins termed nucleoporins (Nups). The 88-kD Nup has been found to be linked in a dynamic subcomplex with the oncogenic CAN/N...

journal_title：Human pathology

authors： Gould VE,Orucevic A,Zentgraf H,Gattuso P,Martinez N,Alonso A

更新日期：2002-05-01 00:00:00

abstract：:The relationship between higher total lymph node resection number in colorectal cancer resection specimens and improved overall survival is well known. Recent studies describe an association between a high rate of microsatellite instability and a high total lymph node count in colorectal cancer. Higher lymph node retr...

journal_title：Human pathology

authors： MacQuarrie E,Arnason T,Gruchy J,Yan S,Drucker A,Huang WY

更新日期：2012-08-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) typically affects male smokers older than 55 years. Recently, an increase in the incidence of HNSCC in young adults has been recognized, many of them nonsmokers and females. Functional inactivation of p16 is known to be a common event in HNSCC, mainly by either deletion or...

journal_title：Human pathology

authors： O'Regan EM,Toner ME,Finn SP,Fan CY,Ring M,Hagmar B,Timon C,Smyth P,Cahill S,Flavin R,Sheils OM,O'Leary JJ

更新日期：2008-03-01 00:00:00

abstract：:Yes-associated protein, a downstream effector of the Hippo signaling pathway, has been linked to progression of non-small-cell lung carcinoma. The aim of this study was to investigate expression of Yes-associated protein in lung adenocarcinoma and squamous cell carcinoma. Associations of Yes-associated protein express...

journal_title：Human pathology

authors： Kim JM,Kang DW,Long LZ,Huang SM,Yeo MK,Yi ES,Kim KH

更新日期：2011-03-01 00:00:00

abstract：:The very late antigens (VLAs) are alpha beta-heterodimeric transmembrane proteins that include surface cell receptors for laminin (VLA-6) and collagen (VLA-2), which mediate cell-matrix and cell-cell adhesion. We investigated the distribution of VLA-6 (alpha 6, beta 1) and VLA-2 (alpha 2, beta 1) proteins in normal, h...

journal_title：Human pathology

authors： Bonkhoff H,Stein U,Remberger K

更新日期：1993-03-01 00:00:00

abstract：:Four surgically resected cardiac valves received from three female patients showed the presence of acute and chronic rheumatic valvulitis. The material was studied by means of transmission and scanning electron microscopy. This is the first time that there has been an investigation of the ultrastructure in acute rheum...

journal_title：Human pathology

authors： Siew S

更新日期：1980-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a commonly occurring tumor in southern China. Although several causative factors have now been recognized, the genetic basis underlying its tumorigenesis is still unclear. To identify potential chromosomal aberrations for further investigations, comparative genomic hybridization (CGH)...

journal_title：Human pathology

authors： Fan CS,Wong N,Leung SF,To KF,Lo KW,Lee SW,Mok TS,Johnson PJ,Huang DP

更新日期：2000-02-01 00:00:00

abstract：:Most failures of bioprosthetic heart valves in children are due to stenosis secondary to thrombus, calcific deposits, or tissue ingrowth. Valve failures due to regurgitation typically involve cuspal detachment, tears, or perforations. We present four cases of prosthetic valve regurgitation in children caused by cuspal...

journal_title：Human pathology

authors： Murphy SK,Rogler WC,Fleming WH,McManus BM

更新日期：1988-02-01 00:00:00

abstract：:To investigate the expression and clinical significance of long noncoding RNA (lncRNA) in gastric cancer, we applied microarray analysis to obtain expression profiles of protein-coding genes and lncRNAs in tumor and paired adjacent nontumor tissues. We found that 41 lncRNAs were up-regulated and 31 lncRNAs were down-r...

journal_title：Human pathology

authors： Li L,Wang YY,Mou XZ,Ye ZY,Zhao ZS

更新日期：2018-08-01 00:00:00

abstract：:High bone marrow mast cell counts before and after marrow transplantation have been reported to predict graft rejection in aplastic anemia. We tested this association by studying marrow specimens from 73 consecutive patients allografted for severe aplastic anemia, 21 of whom rejected. Mast cell counts per unit area we...

journal_title：Human pathology

authors： Sale GE,Marmont P

更新日期：1981-07-01 00:00:00

abstract：:Histological criteria for the diagnosis of reflux esophagitis include basal zone hyperplasia, stromal papillae elongation, and inflammatory infiltrate. However, endoscopic esophageal biopsy specimens may include little or no lamina propria. Intraepithelial T lymphocytes, seen in hematoxylin and eosin-stained sections ...

journal_title：Human pathology

authors： Esposito S,Valente G,Zavallone A,Guidali P,Rapa A,Oderda G

更新日期：2004-01-01 00:00:00

abstract：:Biopsy specimens of sarcoid skin lesions from nine patients with sarcoidosis were examined for the presence of immunoglobulins, complement (C3 and C4), and fibrinogen. Granulomas in all skin lesions were positive only for fibrinogen. The literature relating to the immunohistochemistry of sarcoidosis is reviewed and it...

journal_title：Human pathology

authors： Kataria YP,Zafranas A,Sharma HM

更新日期：1978-09-01 00:00:00

abstract：:Recently, the fusion gene EML4-ALK was identified in non-small cell lung carcinoma, which could be a potential therapeutic target. We investigated the prevalence of anaplastic lymphoma kinase protein expression in these tumors by immunohistochemistry and correlated the results with data from ALK molecular studies. Gen...

journal_title：Human pathology

authors： Boland JM,Erdogan S,Vasmatzis G,Yang P,Tillmans LS,Johnson MR,Wang X,Peterson LM,Halling KC,Oliveira AM,Aubry MC,Yi ES

更新日期：2009-08-01 00:00:00

abstract：:We evaluated 173 consecutive breast carcinomas for c-erbB-2 using a combination of immunohistochemistry (IHC) with a commercial polyclonal antibody (Nitirei) and dual-color fluorescence in situ hybridization (FISH) using the c-erbB-2-specific probe and the chromosome 17 centromere-specific probe from Vysis (Downers Gr...

journal_title：Human pathology

authors： Kobayashi M,Ooi A,Oda Y,Nakanishi I

更新日期：2002-01-01 00:00:00

abstract：:An accurate diagnosis between leiomyoma and leiomyosarcoma is essential for patient management. IMP3 is a member of the insulin-like growth factor (IGF-II) mRNA binding protein (IMP) family that consist of IMP1, IMP2, and IMP3. IMP3 is an oncofetal protein associated with aggressive and advanced tumors and is specific...

journal_title：Human pathology

authors： Cornejo K,Shi M,Jiang Z

更新日期：2012-10-01 00:00:00

abstract：:Twenty-two consecutive cases of adenoma in acromegalic patients were studied immunohistochemically. All the tumors contained prolactin (PRL)-reactive cells (3% to 53% of the total number of tumor cells) as well as growth hormone (GH)-reactive cells (4% to 74% of the total number of tumor cells). All acromegalic cases ...

journal_title：Human pathology

authors： Furuhata S,Kameya T,Otani M,Toya S

更新日期：1993-01-01 00:00:00

abstract：:Cholangiocarcinoma of intrahepatic and extrahepatic bile ducts has a multistep carcinogenesis. Two premalignant lesions have been suggested for invasive cholangiocarcinoma: biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct. How the carcinogenetic process differs between biliary intr...

journal_title：Human pathology

authors： Nakanishi Y,Zen Y,Kondo S,Itoh T,Itatsu K,Nakanuma Y

更新日期：2008-08-01 00:00:00