Abstract：
:Most failures of bioprosthetic heart valves in children are due to stenosis secondary to thrombus, calcific deposits, or tissue ingrowth. Valve failures due to regurgitation typically involve cuspal detachment, tears, or perforations. We present four cases of prosthetic valve regurgitation in children caused by cuspal retraction without stenosis and describe the morphologic findings related to the valves at autopsy or explantation. A mononuclear cell and giant cell response to the cusps of the valve was a striking finding in one patient.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Murphy SK,Rogler WC,Fleming WH,McManus BMdoi
10.1016/s0046-8177(88)80341-1subject
Has Abstractpub_date
1988-02-01 00:00:00pages
140-7issue
2eissn
0046-8177issn
1532-8392pii
S0046-8177(88)80341-1journal_volume
19pub_type
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