Abstract:
:We report the case of an exuberant ulcerative angiomatoid nasal lesion in a cocaine abuser. The lesion was made up of polymorphous endothelial cells with occasional mitoses, arranged in a lobular pattern with infiltrative-looking areas. There were extensive areas of thrombosis with focal recanalization. Intravascular proliferation was not observed. The clinical, radiological, and histological features suggested hemangiosarcoma as the main differential diagnosis, but the lobular architecture of the lesion and the widespread thrombosis favoured the diagnosis of a benign reactive process.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Alameda F,Fontane J,Corominas JM,Lloreta J,Serrano Sdoi
10.1016/s0046-8177(00)80226-9subject
Has Abstractpub_date
2000-02-01 00:00:00pages
239-41issue
2eissn
0046-8177issn
1532-8392pii
S0046-8177(00)80226-9journal_volume
31pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract::This article briefly describes the origin of one of the more common (food-related) pathologic terms--"bread and butter pericarditis." The eminent French physician, Laennec, the inventor of the stethoscope amongst several other important medical contributions, can be credited for having coined the term that is still in...
journal_title:Human pathology
pub_type: 传,历史文章,杂志文章
doi:10.1016/j.humpath.2003.08.029
更新日期:2004-02-01 00:00:00
abstract::Two cystic lesions that were lined by pseudostratified ciliated columnar epithelium containing goblet cells are described. Both lesions were found in the subarachnoid space between the vertebrobasilar arterial system and the brainstem. One cyst was an incidental finding in a patient who died of orbital phycomycosis. T...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80467-1
更新日期:1986-04-01 00:00:00
abstract::Oral contraceptive-associated sinusoidal ectasia is a rare lesion of unknown pathogenesis. We describe the case of a 31-year-old woman who had used oral contraceptives for 10 years and was found to have abnormal liver function tests on "routine" examination. A single 9 x 5 x 4 cm hypervascular lesion was demonstrated ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(92)90411-u
更新日期:1992-08-01 00:00:00
abstract::Deposits found intrauterine contraceptive devices (IUDs) were studied by scanning electron microscopy, x-ray diffraction, and energy dispersive x-ray microanalysis. All seven devices, including five plastic and two copper IUDs, were coated with a crust containing cellular, acellular, and fibrillar material. The cellul...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80160-x
更新日期:1985-07-01 00:00:00
abstract::FoxA1 regulates a variety of tissues during embryogenesis and early life. In thyroid, FoxA1 expression has recently been shown in C cells and medullary thyroid carcinomas but not in follicular cells. FoxA1 has also been proposed as a potential oncogene in anaplastic thyroid carcinomas. However, FoxA1 expression has no...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2017.05.007
更新日期:2017-07-01 00:00:00
abstract::The precise regulation and maintenance of balance between cell proliferation and cell death in multicellular organisms is critical for tissue homeostasis. bcl-2 initiates a new gene family involved in the regulation of cell death and survival without affecting cell proliferation. Expression of Bcl-2 has been reported ...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(96)90362-7
更新日期:1996-02-01 00:00:00
abstract::Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels. The aim of the current study is to identify relationships between VEGF-A and VEGF-C, and their impact in angiogenesis and metastases in thyroid cancers. VEGF-A and VEGF-C mRNA and protein expression was investigated in 136 thyroid...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.04.014
更新日期:2013-10-01 00:00:00
abstract::Dysplastic nevi are an important indicator of risk of cutaneous malignant melanoma. The study of and, particularly, international communication regarding this group of lesions have been hindered by a lack of precision in diagnosis. In an effort to broaden understanding, a panel of pathologists agreed upon a set of cri...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(91)90078-4
更新日期:1991-04-01 00:00:00
abstract::Alterations in the Notch signaling pathway play a role in colorectal cancer (CRC). Hes1, a Notch-induced transcription factor, has recently been reported to show decreased expression by immunohistochemistry in sessile serrated adenomas. Variable staining patterns have been reported in tubular adenomas, and existing da...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2016.07.010
更新日期:2016-11-01 00:00:00
abstract::A case of hemangiopericytoma arising in the esophagus is described. The light microscopic features were typical, and ultrastructural examination confirmed the presence of pericyte-like cells and excluded smooth muscle and fibroblastic differentiation. Areas of necrosis and a focus of mitotic activity within the tumor ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80248-1
更新日期:1981-01-01 00:00:00
abstract::(90)Yttrium (Therasphere) microspheres administered via hepatic artery are a valuable option for treatment of hepatocellular carcinoma. This therapy targets tumor nodules while largely sparing hepatic parenchyma. This retrospective study examines liver explants from 13 adult patients with hepatocellular carcinoma who ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2008.06.024
更新日期:2009-01-01 00:00:00
abstract::Fetal vessels in the placentas of 11 of 15 infants with cerebral palsy contained thrombi. An alternate basis for the injury was identified in the four placentas without thrombi. Autopsy findings in one infant who died at age 1 month confirmed the presence of cerebral thrombi and infarcts. It is concluded that thrombot...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(97)90114-3
更新日期:1997-02-01 00:00:00
abstract::This study tested whether concordance could be achieved for abnormal inflammation in the basal decidua of placental specimens among 6 pathologists experienced in placental pathology. Thirty microscope slides were evaluated by the pathologists for chronic deciduitis. They also scored the severity and extent of inflamma...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(00)80241-5
更新日期:2000-03-01 00:00:00
abstract::Endothelial cell injury may contribute to the progression of various glomerular diseases. In the present study, we examined glomerular capillary injury in acute and chronic glomerular lesions in patients with Immunoglobulin A nephropathy (IgAN). We selected renal biopsy samples of IgAN (n = 200), and glomerular capill...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2015.10.013
更新日期:2016-03-01 00:00:00
abstract::An unusual case of multiple myeloma in an 88-year-old patient is described. Besides skeletal involvement, there was myeloma of the thoracic and abdominal lymph nodes and of the liver and pancreas. In the pancreas, the myeloma extensively involved the head and body, and on computerized tomography scan was suggestive of...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80057-9
更新日期:1982-10-01 00:00:00
abstract::Benign lymphocytic angiitis and granulomatosis is a T-cell lymphoproliferative disorder confined to the lung and corresponding to a low-grade angiocentric immunoproliferative lesion. Controversy remains as to whether these lesions are lymphomas. We report such a case in an 8-year-old patient with Burkitt's lymphoma in...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(92)90041-z
更新日期:1992-10-01 00:00:00
abstract::Decreases in true expenses in the hospital clinical laboratory consequent to reduced utilization were estimated from four models. Each category of direct expense was adjusted according to projections and confirmed to the extent possible by actual experience. No projections of reductions in indirect expenses were made....
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(84)80002-7
更新日期:1984-06-01 00:00:00
abstract::Insulin-like growth factor-II messenger RNA-binding protein 3 (IGF2BP3 or IMP3) is a biomarker whose expression has been found to be a negative prognostic factor in several neoplasms including ovarian clear cell carcinoma (CCC). In this study, we analyzed the frequency and clinicopathologic significance of IMP3 expres...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2012.12.003
更新日期:2013-08-01 00:00:00
abstract::Primary dermal melanoma (PDM) is a rare variant of melanoma which simulates metastatic melanoma to the skin. Diagnosis of PDM cannot be established on histologic grounds alone but requires absence of evidence of melanoma elsewhere by clinical history and/or imaging studies. Despite this entity being clinically well do...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2020.09.002
更新日期:2020-12-01 00:00:00
abstract::Topoisomerase IIalpha (topoIIalpha) is an enzyme required for DNA replication and a molecular target for drugs called anthracyclines. The topoIIalpha gene (TOP2A) is located close to the HER-2/neu oncogene (HER2). We assessed gastric cancers to (1) clarify the relationship between gene amplification and protein overex...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.05.008
更新日期:2006-10-01 00:00:00
abstract::We applied a panel of antibodies to formalin-fixed, paraffin-embedded sections of 55 renal cell carcinomas using a three-stage immunoperoxidase technique. The antibody panel included two anti-keratins, AE1 and CAM5.2, anti-epithelial membrane antigen (EMA), anti-vimentin, anti-S100 protein, and the anti-leukocyte mark...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(88)80016-9
更新日期:1988-08-01 00:00:00
abstract::Yes-associated protein, a downstream effector of the Hippo signaling pathway, has been linked to progression of non-small-cell lung carcinoma. The aim of this study was to investigate expression of Yes-associated protein in lung adenocarcinoma and squamous cell carcinoma. Associations of Yes-associated protein express...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2010.08.003
更新日期:2011-03-01 00:00:00
abstract::An accurate diagnosis between leiomyoma and leiomyosarcoma is essential for patient management. IMP3 is a member of the insulin-like growth factor (IGF-II) mRNA binding protein (IMP) family that consist of IMP1, IMP2, and IMP3. IMP3 is an oncofetal protein associated with aggressive and advanced tumors and is specific...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2011.12.020
更新日期:2012-10-01 00:00:00
abstract::Demonstration of identical allelic loss on chromosome 11q13 in synchronous in situ (DCIS) and invasive ductal (IDC) breast carcinoma has provided molecular evidence of the progression of DCIS to IDC. We investigated loss of heterozygosity (LOH) at chromosome 11q13 in the spectrum of "marker/premalignant" and "malignan...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(97)90124-6
更新日期:1997-03-01 00:00:00
abstract::Nonsteroidal anti-inflammatory drug (NSAID) use is a common cause of peptic ulcer. This study investigated the nature, frequency, and topographic distribution of histological abnormalities of the gastric mucosa associated with chronic NSAID use. A set of 3 to 11 mapped gastric biopsy specimens were obtained from 108 c...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(96)90349-4
更新日期:1996-12-01 00:00:00
abstract::A subset of endometrial polyps recurs after resection. The clinicopathologic significance of the phenomenon is evaluated herein. Consecutive cases of recurrent polyps (index polyp removed by hysteroscopy-directed polypectomy or by curettage; at least one more polyp diagnosed ≤12 months after) were compared with an age...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2020.03.005
更新日期:2020-06-01 00:00:00
abstract::Congenital cystic adenomatoid malformation (CCAM) of the lung is a congenital lesion that is sometimes complicated by bronchioloalveolar adenocarcinoma (BAC). In some cases foci of atypical goblet cell hyperplasia (AGCH) can be found within the cysts. It has been proposed that CCAM and AGCH predispose to the developme...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2004.01.008
更新日期:2004-05-01 00:00:00
abstract::Activating transcription factor 2 (ATF2) is a member of activator protein 1 superfamily, which can heterodimerize with other transcription factors regulating cell differentiation and survival. ATF2 assembles into a complex with the synovial sarcoma translocation, chromosome 18 (SS18)-synovial sarcoma, X breakpoint (SS...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.09.003
更新日期:2014-02-01 00:00:00
abstract::There is limited published data regarding the significance of the number or position of nucleoli and the presence of apoptotic bodies in diagnostically challenging cases of adenocarcinoma of the prostate on needle biopsy material. One hundred consecutive prostate cancers on needle biopsy were sent because of diagnosti...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2005.09.001
更新日期:2005-11-01 00:00:00
abstract::Grade Group (GG) 4 prostate cancer includes Gleason scores (GS) 3 + 5 = 8, 4 + 4 = 8, and 5 + 3 = 8. Some studies without pathology re-review of historical cohorts proposed that the presence of pattern 5 worsens prognosis compared to GS 4 + 4 = 8 cancer. We assessed how often historically graded GS 5 + 3 = 8 cancers r...
journal_title:Human pathology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.humpath.2019.11.002
更新日期:2020-03-01 00:00:00