Abstract：
:Plasmablastic lymphoma (PBL) of the oral cavity is classified as one subtype of diffuse large B-cell lymphoma that is most commonly seen in patients with human immunodeficiency virus infection. We report a rare case of PBL in the anal canal of a 33-year-old man with human immunodeficiency virus infection. The lymphoma cells were positive for CD138 and weakly positive for CD79a. In addition, these cells were also positive for CD10. The neoplastic cells were positive for Epstein-Barr virus and negative for human herpes virus 8. Review of the English medical literature revealed many more cases of extra-oral PBL. We propose that the term plasmablastic lymphoma of the oral cavity in World Health Organization classification be revised to simply plasmablastic lymphoma, which would include both oral and extra-oral PBLs, and the term to define the primary site of the lymphoma (ie, oral cavity) be dropped from the terminology used in World Health Organization classification.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Tavora F,Gonzalez-Cuyar LF,Sun CC,Burke A,Zhao XFdoi
10.1016/j.humpath.2006.04.009subject
Has Abstractpub_date
2006-09-01 00:00:00pages
1233-6issue
9eissn
0046-8177issn
1532-8392pii
S0046-8177(06)00218-8journal_volume
37pub_type
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