Abstract:
:Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic, generalized histiocytic proliferation with marked hemophagocytosis associated with a systemic viral infection. Histologic studies of lymph nodes usually show lymphoid depletion and histiocytic proliferation. In this report we describe the case of a patient with Epstein-Barr virus-associated VAHS in which initial lymph node biopsy samples showed an immunoproliferative lesion that preceded the usual generalized histiocytic proliferation. This finding suggests that some cases of VAHS may have an immunoproliferative precursor lesion.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Daum GS,Sullivan JL,Ansell J,Mulder C,Woda BAdoi
10.1016/s0046-8177(87)80225-3subject
Has Abstractpub_date
1987-10-01 00:00:00pages
1071-4issue
10eissn
0046-8177issn
1532-8392pii
S0046-8177(87)80225-3journal_volume
18pub_type
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