Abstract：
:Two cystic lesions that were lined by pseudostratified ciliated columnar epithelium containing goblet cells are described. Both lesions were found in the subarachnoid space between the vertebrobasilar arterial system and the brainstem. One cyst was an incidental finding in a patient who died of orbital phycomycosis. The cyst was filled with clear mucinous material. The second cyst presented as a mass adjacent to the brainstem in a woman who had progressive brainstem dysfunction. This lesion showed transition from pseudostratified ciliated columnar epithelium with goblet cells to papillary stratified squamous epithelium, histologic features essentially identical to those of squamous papillomas of the nasal cavity. This lesion was filled with squamous debris. The proposed origin of these lesions is discussed.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Schelper RL,Kagan-Hallet KS,Huntington HWdoi
10.1016/s0046-8177(86)80467-1subject
Has Abstractpub_date
1986-04-01 00:00:00pages
417-22issue
4eissn
0046-8177issn
1532-8392pii
S0046-8177(86)80467-1journal_volume
17pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract：:Topoisomerase IIalpha (topoIIalpha) is an enzyme required for DNA replication and a molecular target for drugs called anthracyclines. The topoIIalpha gene (TOP2A) is located close to the HER-2/neu oncogene (HER2). We assessed gastric cancers to (1) clarify the relationship between gene amplification and protein overex...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2006.05.008
更新日期：2006-10-01 00:00:00
abstract：:Basaloid carcinoma (BC) and large-cell neuroendocrine carcinoma (LCNEC) are 2 recently recognized variants of large-cell lung carcinomas that may overlap in their morphology, and are discriminated by expression of neuroendocrine markers in LCNEC. Because thyroid transcription factor 1 (TTF-1) is expressed in lung aden...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1053/hupa.2001.27110
更新日期：2001-09-01 00:00:00
abstract：:We describe the pathology of 5 patients with germline PRKACA copy number gain and Cushing syndrome: 4 males and 1 female, aged 2 to 43 years, including a mother and son. Imaging showed normal or slightly enlarged adrenal glands in 4 patients and a unilateral mass in the fifth. Biochemically, the patients had corticotr...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2014.09.005
更新日期：2015-01-01 00:00:00
abstract：:We studied the histopathologic, immunohistochemical, and ultrastructural features of the extracellular matrix (ECM) in 20 immunologically defined large-cell lymphomas, including immunoblastic sarcoma of B cells (three patients), peripheral T cell lymphoma (five patients), large non-cleaved follicular center cell (FCC)...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(89)90181-0
更新日期：1989-02-01 00:00:00
abstract：:Recently, we reported 2 mixed endometrioid endometrial carcinomas with a "low-grade serous"-like component, which does not fit into any of the 4 molecular groups described by The Cancer Genome Atlas. To understand the nature of these tumors, we have done an immunohistochemical and molecular genetic study of these 2 ca...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2017.10.016
更新日期：2018-01-01 00:00:00
abstract：:Thirty-nine mammographically detected, (M-detected) small invasive carcinomas of the breast (< or = 5 mm) were compared with 78 consecutive clinical cancers (> or = 10 mm) for a variety of morphological and biological markers of prognostic importance. There were more tubular carcinomas in the M-detected group (12.8% v...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(96)90222-1
更新日期：1996-09-01 00:00:00
abstract：:Monoclonal antibodies to somatostatin receptors 2A (SSTR2A, UMB-1) and 5 (SSTR5, UMB-4) were reported to be highly reliable for immunohistochemical detection of these receptors in neuroendocrine neoplasms. However, the standardization of either the immunohistochemical procedure and the methods of evaluation has yet to...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2017.11.008
更新日期：2018-02-01 00:00:00
abstract：:The case of an infant with endocardial fibroelastosis and a coexistent anomalous right coronary artery that originated from the pulmonary trunk is presented. The causal relation between the two conditions is discussed. ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(85)80138-6
更新日期：1985-09-01 00:00:00
abstract：:Although GATA binding protein 3, a zinc finger transcription factor and an estrogen receptor-regulated gene, has recently been suggested as a marker for urothelium, prognostic significance of GATA binding protein 3 expression in bladder tumor remains unclear. We immunohistochemically stained for GATA binding protein 3...
journal_title：Human pathology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.humpath.2012.02.011
更新日期：2012-11-01 00:00:00
abstract：:We have previously reported that the drs gene has the ability to suppress transformation by v-src and v-K-ras in the rat cell line F2808. We have also shown that the expression of drs mRNA is markedly reduced in a variety of human cancer cell lines, suggesting that down-regulation of drs mRNA is correlated with the de...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(03)00240-5
更新日期：2003-07-01 00:00:00
abstract：:A case of hemangiopericytoma arising in the esophagus is described. The light microscopic features were typical, and ultrastructural examination confirmed the presence of pericyte-like cells and excluded smooth muscle and fibroblastic differentiation. Areas of necrosis and a focus of mitotic activity within the tumor ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(81)80248-1
更新日期：1981-01-01 00:00:00
abstract：:Alterations in the Notch signaling pathway play a role in colorectal cancer (CRC). Hes1, a Notch-induced transcription factor, has recently been reported to show decreased expression by immunohistochemistry in sessile serrated adenomas. Variable staining patterns have been reported in tubular adenomas, and existing da...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2016.07.010
更新日期：2016-11-01 00:00:00
abstract：:A 39-year-old female patient was admitted to explore chronic renal failure. Clinical history included silicone breast implants. Clinical examination was normal. Urinalysis revealed tubular proteinuria with Bence-Jones κ protein. Monoclonal immunoglobulin G κ and free monoclonal κ-light chains (LCs) were revealed by se...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2014.10.008
更新日期：2015-01-01 00:00:00
abstract：:Thrombosis of large fetal vessels in the placenta leads to regions of downstream avascular villi (AV). Avascular villi have been associated with adverse outcomes in anecdotal reports, but no controlled study of their significance has been done. We prospectively gathered cases of extensive AV (n = 29) occurring over a ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(95)90118-3
更新日期：1995-01-01 00:00:00
abstract：:The introduction of next-generation sequencing has broadened the genetic landscape of myeloproliferative neoplasms (MPNs) beyond JAK2, MPL, and CALR. However, the biological role and clinical impact of most other mutations are not well defined. We interrogated 101 genes in 143 BCR-ABL1-negative MPNs in chronic phase f...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.11.022
更新日期：2019-04-01 00:00:00
abstract：:A 57 year old man presented with a two week history of right sided chest pain. An admission chest x-ray examination revealed a 2 by 1 cm. lytic lesion of the ninth right rib and right sided pleural effusion. The patient underwent a right thoracotomy during which 700 cc. of blood tinged pleural fluid was drained and a ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(80)80080-3
更新日期：1980-11-01 00:00:00
abstract：:We report novel renal histopathologic features in a patient with hemolytic uremic syndrome after allogeneic bone marrow transplantation who survived with plasma exchange therapy. This distribution of vascular lesions within the kidney differed from previously described cases, which were uniformly fatal, in that there ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(89)90210-4
更新日期：1989-01-01 00:00:00
abstract：:The Association of Directors of Anatomic and Surgical Pathology have developed recommendations for the surgical pathology report for common malignant tumors. The recommendations for carcinomas of the large intestine are reported herein. ...
journal_title：Human pathology
pub_type： 指南,杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Cytogenetic analysis of short-term cultures from 34 benign colorectal polyps, all histologically verified as adenomas, revealed clonal chromosome aberrations in 21 of them. Eight polyps had structural rearrangements, whereas only numerical changes were found in 13. A combination of structural and numerical chromosomal...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(96)90314-7
更新日期：1996-11-01 00:00:00
abstract：:SPARC (secreted protein acidic and rich in cysteine, also called osteonectin, BM-40, and 43K protein) is a matricellular protein and is associated with cell-matrix interactions during cell proliferation and extracellular remodeling. It is also implicated in the neovascularization, invasion, and metastasis of human mal...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1053/hupa.2001.28244
更新日期：2001-10-01 00:00:00
abstract：:Three cases of giant cell carcinoma of lung and six other lung carcinomas with large atypical cell formation were studied by both light and electron microscopy. The giant cell carcinomas showed unique light and electron microscopic features, whereas large atypical cells from other lung carcinomas usually retained some...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(76)80003-2
更新日期：1976-01-01 00:00:00
abstract：:Calcitonin and calcitonin gene-related peptide (CGRP) have been localized immunohistochemically in neuroendocrine cells of normal and diseased human lungs. Cells immunoreactive for calcitonin and CGRP first appeared in immature bronchi in the 27th gestational week. Thereafter, both peptides were found in the same bron...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(89)90103-2
更新日期：1989-09-01 00:00:00
abstract：:Seminoma and sarcoidosis do not seem to be associated diseases, judging from epidemiologic data. The presence of these two diseases in the patient whose case is reported may have been coincidental. It was observed, however, that when the testis tumor appeared in this patient, the longstanding sarcoid lesions significa...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(84)80041-6
更新日期：1984-04-01 00:00:00
abstract：:K homology domain containing protein overexpressed in cancer (KOC) is a member of the insulin-like growth factor (IGF) messenger RNA-binding protein family and is expressed during embryogenesis and in certain malignancies. KOC, known as L523S and IGF messenger RNA-binding protein 3, was shown to be frequently expresse...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2006.11.011
更新日期：2007-04-01 00:00:00
abstract：:Extramammary Paget disease (EMPD) has been known to frequently express androgen receptor (AR). Therefore, androgens could play roles in the biological behavior of Paget cells. 5α-Reductase (5α-red) types 1 and 2 and 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5) are pivotal in situ regulators of androgen productio...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2015.07.007
更新日期：2015-11-01 00:00:00
abstract：:The concurrent presence of JAK2 V617F, monocytosis, and bone marrow fibrosis can be observed in both chronic myelomonocytic leukemia (CMML) and primary myelofibrosis (PMF). It can be challenging to distinguish CMML with JAK2 mutation and fibrosis from other myeloid neoplasms, particularly PMF. To identify key features...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.10.026
更新日期：2019-03-01 00:00:00
abstract：:The pathogenesis of lacaziosis continues to be obscure, and works have investigated the blood systemic immune response or the dermal immune response in restricted lesions in different body regions. Some authors describe that the inflammatory infiltrate in lacaziosis lesions showed a predominance of macrophages followe...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2014.10.016
更新日期：2015-02-01 00:00:00
abstract：:The histologic findings in lymph nodes were used to identify eight patients, who are not in a high-risk group, with human immunodeficiency virus (HIV) infection. In order to determine the specificity of these findings, the histologic and clinical findings in these patients were compared with the histologic and clinica...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(88)80269-7
更新日期：1988-07-01 00:00:00
abstract：:Abnormal nuclear megakaryocytic staining for phospho-STAT5 (pSTAT5) correlates with JAK2 V617F mutational status in non-chronic myelogenous leukemia chronic myeloproliferative disorders. However, a proportion of wild-type JAK2 non-chronic myelogenous leukemia chronic myeloproliferative disorders cases also demonstrate...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2007.10.034
更新日期：2008-07-01 00:00:00
abstract：:Hepatitis C virus (HCV) infection is frequent in human immunodeficiency virus (HIV)-infected patients. It is known to have an aggressive course in significantly immunosuppressed patients, and cirrhosis C has become one of the main causes of mortality in HIV-HCV coinfected patients since the improvement of antiretrovir...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2004.05.009
更新日期：2004-09-01 00:00:00
