Isolated xanthomatosis of the small bowel.

abstract：:A 15 year old girl presented with a painful desquamative rash, fever, and profound hypotension. Despite antimicrobial therapy and intensive supportive measures, she died 80 hours after admission. The premortem skin biopsy and autopsy findings, which included subepidermal edema and blister formation, subacute vasculiti...

journal_title：Human pathology

authors： Abdul-Karim FW,Lederman MM,Carter JR,Hewlett EL,Newman AJ,Greene BM

更新日期：1981-01-01 00:00:00

abstract：:Fourteen chordomas, five myxoid chondrosarcomas, and 15 chondroid tumors (four mesenchymal and 11 conventional chondrosarcomas) were stained for cytokeratin, S-100 protein, carcinoembryonic antigen (CEA), and vimentin. The epithelial markers stained 93 per cent of the chordomas, whereas none of the tumors of other typ...

journal_title：Human pathology

authors： Abenoza P,Sibley RK

更新日期：1986-07-01 00:00:00

abstract：:Thrombosis of large fetal vessels in the placenta leads to regions of downstream avascular villi (AV). Avascular villi have been associated with adverse outcomes in anecdotal reports, but no controlled study of their significance has been done. We prospectively gathered cases of extensive AV (n = 29) occurring over a ...

journal_title：Human pathology

authors： Redline RW,Pappin A

更新日期：1995-01-01 00:00:00

abstract：:We reviewed open lung biopsies from 35 patients with Wegener's (pathergic) granulomatosis in order to study the histogenesis of the pulmonary lesions and to identify the early lesions. The process of pathergic necrosis is fundamental in the production of extravascular and vascular lesions and was divided into micronec...

journal_title：Human pathology

authors： Mark EJ,Matsubara O,Tan-Liu NS,Fienberg R

更新日期：1988-09-01 00:00:00

abstract：:Extranodal natural killer (NK)/T-cell lymphoma, nasal type, is a predominantly extranodal lymphoma associated with Epstein-Barr virus occurring most frequently in the upper aerodigestive tract. There are limited reports on cellular origin and prognostic factors. We retrospectively investigated 73 cases with a median a...

journal_title：Human pathology

authors： Jhuang JY,Chang ST,Weng SF,Pan ST,Chu PY,Hsieh PP,Wei CH,Chou SC,Koo CL,Chen CJ,Hsu JD,Chuang SS

更新日期：2015-02-01 00:00:00

abstract：:A unique case of primary papillary hyperplasia of the gallbladder and cystic and common bile ducts occurring in a young female without calculi, ulcerative colitis, or primary sclerosing cholangitis is reported. The papillary lesion involved the mucosa of the entire gallbladder and of the cystic and common bile ducts. ...

journal_title：Human pathology

authors： Albores-Saavedra J,Defortuna SM,Smothermon WE

更新日期：1990-02-01 00:00:00

abstract：:The non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) are distinguished from classical papillary thyroid carcinoma with predominantly follicular architecture (CPTCPFA) by distinct histomorphologic and molecu...

journal_title：Human pathology

authors： Johnson DN,Sadow PM

更新日期：2018-12-01 00:00:00

abstract：:Chronic myelogenous leukemia (CML) is associated in 95% of cases with the Philadelphia chromosome (Ph1) by cytogenetic analysis. This acquired karyotypic abnormality is the product of a balanced translocation between the c-abl oncogene on chromosome 9 and the breakpoint cluster region (BCR) gene on chromosome 22. The ...

journal_title：Human pathology

authors： McClure JS,Litz CE

更新日期：1994-06-01 00:00:00

abstract：:Monocytoid B-cell lymphoma (MBCL) is a newly recognized, morphologically and immunologically distinct, low-grade B-cell neoplasm that may exist as a pure morphologic entity or as a component of a composite lymphoma. To determine whether cytogenetic abnormalities exist in cases of MBCL, fresh tissue from four lymphoma ...

journal_title：Human pathology

authors： Slovak ML,Weiss LM,Nathwani BN,Bernstein L,Levine AM

更新日期：1993-10-01 00:00:00

abstract：:Oncogenes, growth factors, cell surface receptors, and cell-cycle and apoptotic regulatory proteins have been implicated in the growth regulation and progression of Barrett's-associated neoplasia. Among these, insulin-like growth factor 1 receptor (IGF1-R) and c-Src are reported to be key regulators of mitogenesis and...

journal_title：Human pathology

authors： Iravani S,Zhang HQ,Yuan ZQ,Cheng JQ,Karl RC,Jove R,Coppola D

更新日期：2003-10-01 00:00:00

abstract：:IMP3, an oncofetal protein, is a member of the insulin-like growth factor-II (IGF-II) mRNA-binding protein family. Its relevance as a novel biomarker in lung, pancreatic, renal, and cervical adenocarcinoma was recently revealed. However, its role in breast carcinogenesis and tumor progression is not yet established. B...

journal_title：Human pathology

authors： Walter O,Prasad M,Lu S,Quinlan RM,Edmiston KL,Khan A

更新日期：2009-11-01 00:00:00

abstract：:Acute rejection is an extremely common complication of lung transplantation. (1) To appreciate the interobserver variation in the interpretation of histologic findings and (2) to assess the efficacy of transbronchial biopsy (TBB) for acute rejection diagnosis and associated diseases, particularly infection, we perform...

journal_title：Human pathology

authors： Colombat M,Groussard O,Lautrette A,Thabut G,Marrash-Chahla R,Brugière O,Mal H,Lesèche G,Fournier M,Degott C

更新日期：2005-04-01 00:00:00

abstract：:Spindle cell carcinoma (SpCC) is uncommon, with a predilection for the upper aerodigestive tract. Its histogenesis has not been resolved, although most authors support the sarcomatoid carcinoma concept. Ploidy analysis and proliferation indices have not been reported for laryngeal SpCCs. The authors examined the patho...

journal_title：Human pathology

authors： Lewis JE,Olsen KD,Sebo TJ

更新日期：1997-06-01 00:00:00

abstract：:Biopsy specimens of sarcoid skin lesions from nine patients with sarcoidosis were examined for the presence of immunoglobulins, complement (C3 and C4), and fibrinogen. Granulomas in all skin lesions were positive only for fibrinogen. The literature relating to the immunohistochemistry of sarcoidosis is reviewed and it...

journal_title：Human pathology

authors： Kataria YP,Zafranas A,Sharma HM

更新日期：1978-09-01 00:00:00

abstract：:The striking differences in the histological features of gastric cancers in young and old adults have been thought to be related to differences in the biological behavior of these cancers. Recently, a new grading system (Goseki's classification) showed that the prognosis of the patient is particularly related to the m...

journal_title：Human pathology

authors： Sakamoto H,Yonezawa S,Utsunomiya T,Tanaka S,Kim YS,Sato E

更新日期：1997-09-01 00:00:00

abstract：:Oral cancer overexpressed 1 (ORAOV1) has been reported to exhibit high amplification levels in esophageal squamous cell cancer (ESCC) and in premalignant lesions. However, ORAOV1 protein expression levels in ESCC and esophageal squamous intraepithelial neoplasia (ESIN) have not yet been reported. We have explored the ...

journal_title：Human pathology

authors： Li M,Cui X,Shen Y,Dong H,Liang W,Chen Y,Hu J,Li S,Kong J,Li H,Zhao J,Li F

更新日期：2015-05-01 00:00:00

abstract：:We have begun a systematic study of human papillomavirus (HPV) infection in colposcopically and/or morphologically normal epithelium of the uterine cervix. Paired biopsies were taken from the lesions (cervical intraepithelial neoplasia [CIN], condyloma, invasive carcinoma) and from the normal-appearing adjacent epithe...

journal_title：Human pathology

authors： Colgan TJ,Percy ME,Suri M,Shier RM,Andrews DF,Lickrish GM

更新日期：1989-04-01 00:00:00

abstract：:Angiocentric immunoproliferative lesions (AILs) are believed to represent a unique type of extranodal malignant lymphoma on the basis of clinicopathologic and immunophenotypic evidence. However, molecular studies to assess clonality have been performed on a small number of cases. In this study we assessed the clonalit...

journal_title：Human pathology

authors： Medeiros LJ,Peiper SC,Elwood L,Yano T,Raffeld M,Jaffe ES

更新日期：1991-11-01 00:00:00

abstract：:Abnormalities of the cell cycle are present in all neoplasms. Cyclin E, which regulates the G1/S phase transition of the cell cycle, plays an important role in many different cancers. To further investigate the role of cyclin E in invasive breast ductal carcinomas in South African women, representative sections from 1...

journal_title：Human pathology

authors： Donnellan R,Kleinschmidt I,Chetty R

更新日期：2001-01-01 00:00:00

abstract：:A 61-year-old white woman was found to have disseminated abdominal carcinoma at autopsy. The primary site proved to be a bile duct carcinoma arising from ductal epithelium of multiple von Meyenburg complexes of the liver. No other neoplastic lesion was found elsewhere after careful, gross, microscopic examination. Thi...

journal_title：Human pathology

authors： Honda N,Cobb C,Lechago J

更新日期：1986-12-01 00:00:00

abstract：:Five hundred eighty renal biopsies from a pool of 27850 archived cases were identified in which a myoglobin stain was performed because of atypical casts. Two hundred and thirty-eight (41%) of these biopsies were found to be positive for myoglobin casts. The morphology of the myoglobin casts ranged from light, almost ...

journal_title：Human pathology

authors： Liapis H,Boils C,Hennigar R,Silva F

更新日期：2016-08-01 00:00:00

abstract：:Pleomorphic adenomas of the breast (PAB) are uncommon tumors. We studied the clinicopathologic features of 10 cases of PAB, seven of which were assessed immunohistochemically. Nine patients were women, with a median age at diagnosis of 65 years. Eight patients presented with a palpable mass; two had a nipple discharge...

journal_title：Human pathology

authors： Diaz NM,McDivitt RW,Wick MR

更新日期：1991-12-01 00:00:00

abstract：:We describe a patient with adenosquamous carcinoma of the prostate. His history suggests a common histogenesis of the glandular and squamous elements of the tumor. A 60-year-old white man had adenocarcinoma of the prostate diagnosed by biopsy and then underwent radical prostatectomy, which showed adenosquamous carcino...

journal_title：Human pathology

authors： Gattuso P,Carson HJ,Candel A,Castelli MJ

更新日期：1995-01-01 00:00:00

abstract：:The present report is a neuropathologic study of three patients who died from a severe form of necrotizing encephalopathy following intrathecal methotrexate therapy and craniospinal irradiation for acute lymphoblastic leukemia. During the early phase the lesion presented as multifocal coalescing areas of coagulation n...

journal_title：Human pathology

authors： Liu HM,Maurer HS,Vongsvivut S,Conway JJ

更新日期：1978-11-01 00:00:00

abstract：:The Mix1 homeobox-like (MIXL1) gene encodes a paired class homeobox transcription factor that is involved in embryogenesis. Previous studies have shown that the MIXL1 gene product is expressed in B- and T-cell progenitors of normal bone marrow and, in some cell lines derived from hematopoietic neoplasms. The status of...

journal_title：Human pathology

authors： Drakos E,Rassidakis GZ,Leventaki V,Guo W,Medeiros LJ,Nagarajan L

更新日期：2007-03-01 00:00:00

abstract：:The types of collagen present in a case of elastofibroma dorsi were determined using type specific, characterized collagen antibodies. The presence of type II collagen (normally present only in articular cartilage and in selected ocular structures) is discussed with regard to the pathogenesis of this lesion, and the u...

journal_title：Human pathology

authors： Madri JA,Dise CA,LiVolsi VA,Merino MJ,Bibro MC

更新日期：1981-02-01 00:00:00

abstract：:Automatic quantification of cardinal histologic features of nonalcoholic fatty liver disease (NAFLD) may reduce human variability and allow continuous rather than semiquantitative assessment of injury. We recently developed an automated classifier that can detect and quantify macrosteatosis with greater than or equal ...

journal_title：Human pathology

authors： Vanderbeck S,Bockhorst J,Kleiner D,Komorowski R,Chalasani N,Gawrieh S

更新日期：2015-05-01 00:00:00

abstract：:A rare example of melanoma arising in carcinoma ex pleomorphic adenoma is presented. The diagnosis, differential diagnosis, and putative histogenesis of the melanoma component are discussed. ...

journal_title：Human pathology

authors： Karpowicz MK,Shalmon B,Molberg KH,El-Naggar AK

更新日期：2011-09-01 00:00:00

abstract：:Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic, generalized histiocytic proliferation with marked hemophagocytosis associated with a systemic viral infection. Histologic studies of lymph nodes usually show lymphoid depletion and histiocytic proliferation. In this report we describe the case of a pa...

journal_title：Human pathology

authors： Daum GS,Sullivan JL,Ansell J,Mulder C,Woda BA

更新日期：1987-10-01 00:00:00

abstract：:Most human papillomavirus-associated squamous intraepithelial lesions of the uterine cervix are flat; some have papillary architecture that shows a spectrum of differentiation from low-grade squamous intraepithelial lesions to high-grade squamous intraepithelial lesions. For this subset of lesions, there are few data ...

journal_title：Human pathology

authors： Liang CW,Lin MC,Hsiao CH,Lin YT,Kuo KT

更新日期：2010-03-01 00:00:00