Chordoma: an immunohistologic study.

Abstract:

:Fourteen chordomas, five myxoid chondrosarcomas, and 15 chondroid tumors (four mesenchymal and 11 conventional chondrosarcomas) were stained for cytokeratin, S-100 protein, carcinoembryonic antigen (CEA), and vimentin. The epithelial markers stained 93 per cent of the chordomas, whereas none of the tumors of other types showed any staining. Sixty-four per cent of the chordomas, 20 per cent of the myxoid chondrosarcomas, and 87 per cent of the other chondroid tumors were positive for S-100 protein. All of the tumors were positive for vimentin. Three of the 14 chordomas were positive for CEA. The present study confirms the utility of these markers in the differential diagnosis of chordoma and tumors with similar histologic characteristics.

journal_name

Hum Pathol

journal_title

Human pathology

authors

Abenoza P,Sibley RK

doi

10.1016/s0046-8177(86)80185-x

subject

Has Abstract

pub_date

1986-07-01 00:00:00

pages

744-7

issue

7

eissn

0046-8177

issn

1532-8392

pii

S0046-8177(86)80185-X

journal_volume

17

pub_type

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