Abstract:
:Fourteen chordomas, five myxoid chondrosarcomas, and 15 chondroid tumors (four mesenchymal and 11 conventional chondrosarcomas) were stained for cytokeratin, S-100 protein, carcinoembryonic antigen (CEA), and vimentin. The epithelial markers stained 93 per cent of the chordomas, whereas none of the tumors of other types showed any staining. Sixty-four per cent of the chordomas, 20 per cent of the myxoid chondrosarcomas, and 87 per cent of the other chondroid tumors were positive for S-100 protein. All of the tumors were positive for vimentin. Three of the 14 chordomas were positive for CEA. The present study confirms the utility of these markers in the differential diagnosis of chordoma and tumors with similar histologic characteristics.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Abenoza P,Sibley RKdoi
10.1016/s0046-8177(86)80185-xsubject
Has Abstractpub_date
1986-07-01 00:00:00pages
744-7issue
7eissn
0046-8177issn
1532-8392pii
S0046-8177(86)80185-Xjournal_volume
17pub_type
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