EWSR1-ATF1 chimeric transcript in a myoepithelial tumor of soft tissue: a case report.

abstract：:Clinical stage I seminomas are effectively treated with surgery raising concerns as to when to give adjuvant radiation therapy given the risk of secondary malignancies. A recent randomized trial found tumor size and rete testis invasion to be the strongest predictors of relapse in clinical stage I seminomas. These 2 p...

journal_title：Human pathology

authors： Browne TJ,Richie JP,Gilligan TD,Rubin MA

更新日期：2005-06-01 00:00:00

abstract：:Thirty cases of ductal carcinoma in situ (DCIS) of the breast, showing histological microcalcifications, were studied to clarify their mechanism of formation. Undecalcified sections revealed three types of calcium precipitates: type I and II granular calcifications (GCs) and laminar calcifications (LCs). In type I GCs...

journal_title：Human pathology

authors： Foschini MP,Fornelli A,Peterse JL,Mignani S,Eusebi V

更新日期：1996-02-01 00:00:00

abstract：:Parakeratosis refers to incomplete maturation of epidermal keratinocytes, resulting in abnormal retention of nuclei in the stratum corneum. It occurs in many diseases of the skin, particularly in psoriasis. Down-regulation of inhibitor of differentiation 4 messenger RNA has been demonstrated in psoriatic skin, but the...

journal_title：Human pathology

authors： Ruchusatsawat K,Wongpiyabovorn J,Protjaroen P,Chaipipat M,Shuangshoti S,Thorner PS,Mutirangura A

更新日期：2011-12-01 00:00:00

abstract：:Adamantinoma of the long bones is a rare, typically low-grade malignant tumor that frequently involves the tibia. Radiographically, adamantinoma is characteristically a lytic, intracortical, and expansile lesion with variable margins. Histologically, adamantinoma is a bimorphic neoplasm, composed of epithelial and ost...

journal_title：Human pathology

authors： Dashti NK,Howe BM,Inwards CY,Fritchie KJ,Carter JM

更新日期：2019-09-01 00:00:00

abstract：:Decreases in true expenses in the hospital clinical laboratory consequent to reduced utilization were estimated from four models. Each category of direct expense was adjusted according to projections and confirmed to the extent possible by actual experience. No projections of reductions in indirect expenses were made....

journal_title：Human pathology

authors： Winkelman JW

更新日期：1984-06-01 00:00:00

abstract：:AT-rich interaction domain 4B (ARID4B), which belongs to the ARID family, is heavily involved in cell growth and differentiation and is closely associated with many types of tumors. However, the role of this protein in hepatocellular carcinoma (HCC) remains unknown. In this study, we used data from The Cancer Genome A...

journal_title：Human pathology

authors： Wang R,Yu Z,Chen F,Liao C,Wang Q,Huang X

更新日期：2018-03-01 00:00:00

abstract：:To investigate the possibility of human immunodeficiency virus-(HIV) 1 infection of liver cells, liver samples from 17 patients with either acquired immunodeficiency syndrome (AIDS, 13), AIDS-related complex (ARC, 3), or lymphadenopathy syndrome (LAS, 1) were studied. A monoclonal antibody directed against the p24 gag...

journal_title：Human pathology

authors： Housset C,Boucher O,Girard PM,Leibowitch J,Saimot AG,Bréchot C,Marche C

更新日期：1990-04-01 00:00:00

abstract：:Angiotropic lymphoma (AL) is an unusual variant of extranodal lymphoma, characterized by massive proliferation of neoplastic lymphoid cells almost exclusively within blood vessels. Whereas the lymphoid origin of this disease is widely accepted it still remains unclear whether AL is a distinct entity that originates in...

journal_title：Human pathology

authors： Evert M,Lehringer-Polzin M,Möbius W,Pfeifer U

更新日期：2000-07-01 00:00:00

abstract：:Plasma cells are the hallmark of chronic endometritis but are not specific for upper tract infection. Plasma cells have also been noted in hormonally mediated endometrial disorders in association with gland architectural changes ("disordered proliferative" and "anovulatory" patterns), and stromal breakdown. We reviewe...

journal_title：Human pathology

authors： Gilmore H,Fleischhacker D,Hecht JL

更新日期：2007-04-01 00:00:00

abstract：:Extramammary Paget disease (EMPD) has been known to frequently express androgen receptor (AR). Therefore, androgens could play roles in the biological behavior of Paget cells. 5α-Reductase (5α-red) types 1 and 2 and 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5) are pivotal in situ regulators of androgen productio...

journal_title：Human pathology

authors： Azmahani A,Nakamura Y,Ozawa Y,McNamara KM,Fujimura T,Haga T,Hashimoto A,Aiba S,Sasano H

更新日期：2015-11-01 00:00:00

abstract：:This report describes a 47-year-old man with Erdheim-Chester disease (EC), the second case reported in Japan. The patient complained of knee pain, and the roentgenogram of the bilateral legs revealed symmetric osteolytic lesions with sclerosis of the metaphyseal regions of the long bones. Histological examination of t...

journal_title：Human pathology

authors： Ono K,Oshiro M,Uemura K,Ota H,Matsushita Y,Ijima S,Iwase T,Uchida M,Katsuyama T

更新日期：1996-01-01 00:00:00

abstract：:Invasive mammary carcinoma with neuroendocrine differentiation has been controversial in terms of its definition and clinical outcome. In 2003, the World Health Organization histologic classification of tumors designated this entity as neuroendocrine carcinoma of the breast and defined mammary neuroendocrine carcinoma...

journal_title：Human pathology

authors： Tian Z,Wei B,Tang F,Wei W,Gilcrease MZ,Huo L,Albarracin CT,Resetkova E,Middleton L,Sahin A,Xing Y,Hunt KK,Chen J,Bu H,Rashid A,Abraham SC,Wu Y

更新日期：2011-08-01 00:00:00

abstract：:Micropapillary carcinoma of the breast is associated with increased rates of lymph node metastasis and lymphovascular invasion. While activating point mutations in PIK3CA (encoding phosphatidylinositol-3-kinase catalytic subunit) or AKT1 are found in 25% to 30% of invasive ductal carcinomas, the mutational profile of ...

journal_title：Human pathology

authors： Flatley E,Ang D,Warrick A,Beadling C,Corless CL,Troxell ML

更新日期：2013-07-01 00:00:00

abstract：:T-lymphocyte subsets in peripheral blood, bronchoalveolar lavage fluid, and prescalenic lymph nodes from eight patients with sarcoidosis were evaluated with monoclonal antibodies. Both in lung and lymph nodes significant increases in helper T cells were demonstrated, except in patients with stage III pulmonary disease...

journal_title：Human pathology

authors： Viale G,Codecasa L,Bulgheroni P,Giobbi A,Madonini E,Dell'Orto P,Coggi G

更新日期：1986-05-01 00:00:00

abstract：:GAEC1 is a novel gene located at 7q22.1 that was detected in our previous work in esophageal cancer. The aims of the present study are to identify the copy number of GAEC1 in different colorectal tissues including carcinomas, adenomas, and nonneoplastic tissues and characterize any links to pathologic factors. The cop...

journal_title：Human pathology

authors： Gopalan V,Smith RA,Nassiri MR,Yasuda K,Salajegheh A,Kim SY,Ho YH,Weinstein S,Tang JC,Lam AK

更新日期：2010-07-01 00:00:00

abstract：:To elucidate the pathogenesis of aging changes and their relation to age associated calcification, a morphological study of 27 human aortic valves was carried out. Nine valves were obtained from immediate autopsies and 18 valves from routine autopsies done within four hours after death. Calcium deposition was present ...

journal_title：Human pathology

authors： Kim KM,Valigorsky JM,Mergner WJ,Jones RT,Pendergrass RF,Trump BF

更新日期：1976-01-01 00:00:00

abstract：:The aim of the study was to evaluate the impact of the updated 2018 American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guideline on human epidermal growth factor receptor 2 (HER2) interpretation in breast cancer compared with that of the previous guidelines and also the significance of...

journal_title：Human pathology

authors： Woo JW,Lee K,Chung YR,Jang MH,Ahn S,Park SY

更新日期：2020-04-01 00:00:00

abstract：:Monocytoid B-cell lymphoma (MBCL) is a newly recognized, morphologically and immunologically distinct, low-grade B-cell neoplasm that may exist as a pure morphologic entity or as a component of a composite lymphoma. To determine whether cytogenetic abnormalities exist in cases of MBCL, fresh tissue from four lymphoma ...

journal_title：Human pathology

authors： Slovak ML,Weiss LM,Nathwani BN,Bernstein L,Levine AM

更新日期：1993-10-01 00:00:00

abstract：:The reticulin stain is a critical diagnostic aide used to differentiate benign hepatocellular proliferations from well differentiated hepatocellular carcinoma (HCC). Rarely, however, hepatocellular carcinomas do not show definitive loss of reticulin in liver biopsy specimens. To study this group of tumors, 11 HCC with...

journal_title：Human pathology

authors： Yasir S,Chen ZE,Said S,Wu TT,Torbenson M

更新日期：2021-01-01 00:00:00

abstract：:Desmoplastic infantile astrocytoma/ganglioglioma (DIA/DIG) are rare primary glioneuronal tumors that comprise 0.5% to 1.0% of all intracranial tumors. While BRAF mutation is found in up to 50% of pediatric gangliogliomas, data for DIA/DIGs is limited. This study was carried out to evaluate the frequency of BRAF V600E ...

journal_title：Human pathology

authors： Chatterjee D,Garg C,Singla N,Radotra BD

更新日期：2018-10-01 00:00:00

abstract：:Ground-glass hepatocytes are seen in chronic hepatitis B virus (HBV) infection and are known to harbor pre-S mutants, which are implicated in the pathogenesis of hepatocellular carcinoma (HCC). However, the association between ground-glass hepatocytes and HCC has yet to be clearly elucidated. The aim in the present st...

journal_title：Human pathology

authors： Mathai AM,Alexander J,Kuo FY,Torbenson M,Swanson PE,Yeh MM

更新日期：2013-08-01 00:00:00

abstract：:Pleomorphic adenomas of the breast (PAB) are uncommon tumors. We studied the clinicopathologic features of 10 cases of PAB, seven of which were assessed immunohistochemically. Nine patients were women, with a median age at diagnosis of 65 years. Eight patients presented with a palpable mass; two had a nipple discharge...

journal_title：Human pathology

authors： Diaz NM,McDivitt RW,Wick MR

更新日期：1991-12-01 00:00:00

abstract：:Differentiation features and proliferation activity of 67 gastric microleiomyomas (microLMs) and 53 clinical gastrointestinal stromal tumors (GISTs) of the stomach were compared. The 67 microLMs were divided into two categories on the basis of cellularity: 53 hypocellular and 14 hypercellular types, and the 39 GISTs w...

journal_title：Human pathology

authors： Mikami T,Terada T,Nakamura K,Okayasu I

更新日期：1997-12-01 00:00:00

abstract：:The assessment of hormone receptors, including estrogen receptor and progesterone receptor, has become a standard practice in breast cancer management. However, the need for multiple sections to evaluate each receptor individually by conventional immunohistochemistry may preclude the analysis on some core biopsies wit...

journal_title：Human pathology

authors： Yu J,Monaco SE,Onisko A,Bhargava R,Dabbs DJ,Cieply KM,Fine JL

更新日期：2013-03-01 00:00:00

abstract：:The aim of this study was to examine the relation between cofilin 1 expression and progression-free survival in advanced epithelial ovarian cancer. We performed quantitative reverse transcriptase polymerase chain reaction and immunohistochemical analysis in 78 patients with advanced epithelial ovarian cancer (excludin...

journal_title：Human pathology

authors： Nishimura S,Tsuda H,Kataoka F,Arao T,Nomura H,Chiyoda T,Susumu N,Nishio K,Aoki D

更新日期：2011-04-01 00:00:00

abstract：:Two patients, 14 and 46 years of age, presented with diffuse, rapidly growing intracerebral tumors leading to death 6 1/2 and 9 1/2 months, respectively, after diagnosis. Histological examination showed sheets of moderate-sized tumor cells with clear cytoplasm and central nuclei interrupted by delicate arciform vascul...

journal_title：Human pathology

authors： Mrak RE

更新日期：1994-08-01 00:00:00

abstract：:A solitary fibrous tumor (SFT) is a rare, NAB2-STAT6 fusion gene-associated mesenchymal neoplasm. It most commonly arises in the pleural site, but it can occur at many other sites, and rarely also in the head and neck (H&N) region. STFs may show many growth patterns and therefore can be easily mistaken for other more ...

journal_title：Human pathology

authors： Baněčková M,Martínek P,Skálová A,Mezencev R,Hadravský L,Michal M,Švajdler M

更新日期：2020-05-01 00:00:00

abstract：:Cancer-related axonogenesis and neurogenesis are recently described biologic phenomena. Our previously published data showed that nerve density and the number of neurons in the parasympathetic ganglia are increased in prostate cancer (PCa) and associated with aggressive disease. Tissue microarrays were constructed fro...

journal_title：Human pathology

authors： Olar A,He D,Florentin D,Ding Y,Ayala G

更新日期：2014-07-01 00:00:00

abstract：:It has been proposed that an epithelial injury may be one of the multiple primary events in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The aim of this study was to characterize the tight junction and adherens junction proteins in normal human lung, IPF, cryptogenic organizing pneumonia, and asbestosis. W...

journal_title：Human pathology

authors： Lappi-Blanco E,Lehtonen ST,Sormunen R,Merikallio HM,Soini Y,Kaarteenaho RL

更新日期：2013-05-01 00:00:00

abstract：:Nested urothelial carcinoma (UC) is a rare histologic variant of UC, characterized by deceptively bland histologic features resembling von Brunn's nests but usually with a poor outcome. In our experience, this variant is frequently misclassified or underrecognized as its clinicopathologic spectrum is not well defined....

journal_title：Human pathology

authors： Wasco MJ,Daignault S,Bradley D,Shah RB

更新日期：2010-02-01 00:00:00