Abstract：
:Although the term "thyroiditis" suggests inflammation, many disorders of the thyroid that are of unknown etiology are also currently included under this heading. Thus, only infective thyroiditis and subacute thyroiditis are clearly inflammatory; autoimmune thyroiditis is a result of lymphocytic and fibroblastic infiltration secondary to immune processes, and Riedel's struma (a rare disorder) results from a curious form of fibroblastic proliferation of unknown nature. The pathology of infective thyroiditis is that of the particular infective organism. The picture of subacute thyroiditis is that of a unique type of follicular disruption with histiocytes surrounding extravasated colloid masses, producing the appearance of giant cells. Autoimmune thyroiditis is characterized by lymphocytic infiltration, lymphoid follicles. Askanazy cells, and fibrosis, each to a variable degree, with atrophy of follicles. The fibroblastic proliferation in Riedel's struma transcends the thyroid capsule and involves adjacent tissues. The electron microscopic appearance of each form of thyroiditis is also briefly described.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Volpé Rdoi
10.1016/s0046-8177(78)80028-8subject
Has Abstractpub_date
1978-07-01 00:00:00pages
429-38issue
4eissn
0046-8177issn
1532-8392pii
S0046-8177(78)80028-8journal_volume
9pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract：:A primary neoplasm of the proximal humerus in a 68-year-old woman was unique histologically in that it contained both malignant cartilaginous and squamous cell components. The epithelial differentiation was confirmed by the demonstration of keratin by immunohistochemical techniques and of basement membrane, tonofilame...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(83)80227-5
更新日期：1986-03-01 00:00:00
abstract：:Cytochrome P-450 specific for steroid 17 alpha-hydroxylation (P-45017 alpha) was immunolocalized in normal and hyperfunctioning adrenal glands of pigs, bovines, and humans, using a specific IgG fraction raised against the enzyme. P-45017 alpha was present in the zona fasciculata (ZF) and zona reticularis (ZR), but not...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(89)90174-3
更新日期：1989-02-01 00:00:00
abstract：:The clinicopathologic features and immunohistochemical profiles of 14 cases of a distinctive mesenchymal tumor that arises in the superficial lamina propria of the cervix and vagina and is histologically distinguishable from mesodermal (fibroepithelial) stromal polyp, including the cellular (pseudosarcomatous) variant...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1053/hupa.2001.25588
更新日期：2001-07-01 00:00:00
abstract：:The synovium in two well-documented cases of alkaptonuric ochronosis was studied by transmission electron and light microscopy. A feature of alkaptonuria previously unreported in the English-language literature was the presence of phagocytosis of large collagen fibrils by synovial macrophages in both cases. The origin...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(87)80385-4
更新日期：1987-11-01 00:00:00
abstract：:It is currently thought that most clear cell and endometrioid carcinomas arise from ovarian endometriosis. We recently suggested that, besides their origin in the ovary, reduction of CDC42 messenger RNA (a member of the RHO GTPase family) may contribute to explain why clear cell carcinomas are not uncommonly found lim...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.06.020
更新日期：2012-05-01 00:00:00
abstract：:Microsatellite instability (MSI) defines a specific type of genetic instability. Although consensus diagnostic criteria for MSI definition in colorectal cancer have been established, their utility in other tumor types remain to be proven. Previously we developed a mathematical model for MSI definition in colorectal ca...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2003.10.021
更新日期：2004-03-01 00:00:00
abstract：:Langerhans cell histiocytosis (LCH) is a group of granulomatous disorders in which abnormal Langerhans cells proliferate as either a localized lesion in a single bone or disseminated disease involving two or more organs or systems. Because the different LCH forms exhibit significantly elevated levels of inflammatory m...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2013.05.028
更新日期：2014-01-01 00:00:00
abstract：:The Ewing family of tumors (EFT) is characterized by high MIC2/CD99 expression and specific EWS/ETS gene rearrangements, resulting in different chimeric transcripts. Further division into peripheral primitive neuroectodermal tumors and Ewing's sarcoma is still debated and, in the absence of distinct morphological para...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(99)90223-x
更新日期：1999-09-01 00:00:00
abstract：:A case of metastatic malignant melanoma simulating a giant cell tumor of bone is reported. This case typifies the diversity of expression of malignant melanoma. Osteoclast-like giant cells were present only in the femoral head metastasis and were not present in the primary lesion. The giant cell component may be refle...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(90)90183-6
更新日期：1990-09-01 00:00:00
abstract：:Benign lymphocytic angiitis and granulomatosis is a T-cell lymphoproliferative disorder confined to the lung and corresponding to a low-grade angiocentric immunoproliferative lesion. Controversy remains as to whether these lesions are lymphomas. We report such a case in an 8-year-old patient with Burkitt's lymphoma in...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(92)90041-z
更新日期：1992-10-01 00:00:00
abstract：:Ovarian ependymomas are rare glial neoplasms that typically occur in women on their third to fourth decades of life. They are histologically similar to ependymomas of the central nervous system but may have a broader immunophenotype. We describe a 27-year-old woman who presented to the emergency department with a 3-we...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.06.019
更新日期：2019-01-01 00:00:00
abstract：:The current World Health Organization classification considers myelodysplastic syndrome with isolated del(5q) a distinct entity owing to its characteristic clinical and pathologic features. Recently, several studies have examined survival, leukemic transformation, and various prognostic factors in these patients. Howe...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2012.05.022
更新日期：2013-03-01 00:00:00
abstract：:Urethral caruncle is a benign polypoid mass of the urethral meatus in primarily postmenopausal women. Although a conclusive association with malignancy, urologic disorder, or systemic disease has not been established, often the lesion carries a challenging clinical differential diagnosis that includes malignancy. Conv...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.10.015
更新日期：2012-09-01 00:00:00
abstract：:Trefoil factors are wound-healing peptides important in protection and healing of the human gastrointestinal tract. Their potential for therapy of gastrointestinal ulcers has been established. This study investigated the hypothesis that trefoil factors are also present in human salivary gland. Tissues from surgical bi...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1053/hp.2000.6549
更新日期：2000-04-01 00:00:00
abstract：:The reticulin stain is a critical diagnostic aide used to differentiate benign hepatocellular proliferations from well differentiated hepatocellular carcinoma (HCC). Rarely, however, hepatocellular carcinomas do not show definitive loss of reticulin in liver biopsy specimens. To study this group of tumors, 11 HCC with...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2020.09.015
更新日期：2021-01-01 00:00:00
abstract：:Lymphocytic colitis (LC) and LC incomplete (LCi) are common causes of chronic watery diarrhea. The diagnosis relies on clinical findings and histopathologic evaluation. The diagnostic criteria of LC are based on hematoxylin and eosin (HE) staining. However, supplementary immunohistochemical staining for highlighting t...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.08.031
更新日期：2019-02-01 00:00:00
abstract：:Blue nevus is an uncommon pigmented tumor of dermal melanocytes that has traditionally been classified into common and cellular variant. It is usually a skin tumor in adults but can become apparent in early childhood or even be present at birth. Malignant blue nevus is a rare melanocytic tumor of the skin arising from...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2004.07.012
更新日期：2004-10-01 00:00:00
abstract：:Seminoma and sarcoidosis do not seem to be associated diseases, judging from epidemiologic data. The presence of these two diseases in the patient whose case is reported may have been coincidental. It was observed, however, that when the testis tumor appeared in this patient, the longstanding sarcoid lesions significa...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(84)80041-6
更新日期：1984-04-01 00:00:00
abstract：:Secretory carcinoma (SC) of the salivary gland is a low-grade malignancy associated with a well-defined clinical, histologic, immunohistochemical, and cytogenetic signature. Although the t(12;15) (p13;q25) translocation resulting in an ETV6-NTRK3 gene fusion is well documented, advances in molecular profiling in saliv...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.08.011
更新日期：2019-01-01 00:00:00
abstract：:Digitization of histologic slides is associated with many advantages, and its use in routine diagnosis holds great promise. Nevertheless, few articles evaluate virtual microscopy in routine settings. This study is an evaluation of the validity and diagnostic performance of virtual microscopy in routine histologic diag...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2010.05.015
更新日期：2010-12-01 00:00:00
abstract：:Micropapillary carcinoma is a histologic pattern, rather than an independent entity, that has an aggressive clinical behavior regardless of location. Histologically, it is characterized by papillary cell groups in clear spaces. The micropapillary pattern in the thyroid gland has not been studied until recently but und...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.10.027
更新日期：2012-10-01 00:00:00
abstract：:Disheveled-axin (DIX) domain containing 1 (DIXDC1), a protein containing a coiled-coil domain and a DIX domain, is involved in the progression of multiple cancers. However, the role of DIXDC1 in human pancreatic ductal adenocarcinoma (PDAC) remains unclear. In this study, we investigated the role and prognostic value ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2016.07.015
更新日期：2016-11-01 00:00:00
abstract：:The objective of this study was to compare the expression of the nerve growth factor (NGF) receptors TrkA and p75 in ovarian borderline tumors, International Federation of Gynecology and Obstetrics (FIGO) stage I carcinomas and advanced-stage (FIGO stage III-IV) carcinomas, and to assess a possible association between...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2006.06.027
更新日期：2007-01-01 00:00:00
abstract：:Mesenchymal chondrosarcoma, a rare malignant round cell and hyaline cartilage tumor, is most commonly intraosseous but can occur in extraskeletal sites. We intensively observed the morphology and applied Sox9 (master regulator of chondrogenesis), beta-catenin (involved in bone formation, thought to inhibit chondrogene...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2009.11.006
更新日期：2010-05-01 00:00:00
abstract：:We studied renal tissues from 203 patients with acquired immunodeficiency syndrome (AIDS). Of the 203 patients, 20 showed light-microscopic changes characteristic of AIDS-associated nephropathy (AAN). Fifteen of the 20 (group A) were examined by immunohistochemistry using Mycoplasma fermentans (incognitus strain)-spec...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(91)90063-u
更新日期：1991-01-01 00:00:00
abstract：:Pulmonary vein stenosis (PVS) is a rare disorder. Accurate diagnosis often requires anatomical examination. We report four children with pulmonary vein stenosis. Autopsy showed bilateral lesions in two patients who were thought clinically to have unilateral disease. A diagnosis of PVS was made at autopsy in the third ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(95)90011-x
更新日期：1995-08-01 00:00:00
abstract：:The peroxidase-antiperoxidase immunohistochemical technique was employed to stain formalin fixed, paraffin embedded tissue sections from three cases of encephalitis caused by Toxoplasma gondii. We studied two cases of congenital infection and one case of acquired toxoplasmosis occurring in an immunocompromised host. T...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(81)80170-0
更新日期：1981-08-01 00:00:00
abstract：:Total parenteral nutrition (TPN) therapy is a well-recognized cause of liver injury. The histologic changes attributed to TPN in the literature vary widely. In this study, we describe the histopathologic changes associated with TPN therapy and relate these changes to various clinical parameters. We conducted a retrosp...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.07.008
更新日期：2012-06-01 00:00:00
abstract：:The aim of the study was to evaluate the impact of the updated 2018 American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guideline on human epidermal growth factor receptor 2 (HER2) interpretation in breast cancer compared with that of the previous guidelines and also the significance of...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2020.01.003
更新日期：2020-04-01 00:00:00
abstract：:We report two cases of allergic bronchopulmonary fungal disease (ABPFD) caused by Curvularia sp and associated with allergic fungal sinusitis (AFS). Curvularia lunata was cultured in one case and Curvularia senegalensis was cultured in the other. Based on these cases and a review of the literature, we discuss unusual ...
journal_title：Human pathology
pub_type： 杂志文章,评审
doi：10.1016/0046-8177(91)90106-y
更新日期：1991-12-01 00:00:00
