Abstract：
:Blue nevus is an uncommon pigmented tumor of dermal melanocytes that has traditionally been classified into common and cellular variant. It is usually a skin tumor in adults but can become apparent in early childhood or even be present at birth. Malignant blue nevus is a rare melanocytic tumor of the skin arising from a preexisting cellular blue nevus. We report a multinodular blue nevus of the left ear in an 11-year-old girl who also had 2 intracranial melanocytic lesions. Differential diagnosis between metastases from malignant blue nevus and neurocutaneous melanosis is discussed.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Popović M,Dolenc-Strazar Z,Anzic J,Luzar Bdoi
10.1016/j.humpath.2004.07.012subject
Has Abstractpub_date
2004-10-01 00:00:00pages
1292-6issue
10eissn
0046-8177issn
1532-8392pii
S0046817704004150journal_volume
35pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract：:DNA methyltransferase 1, 3a, and 3b affect DNA methylation, and it is thought that they play an important role in the malignant transformation of various cancers. The current study was designed to analyze DNA methyltransferase expression by immunohistochemistry in a series of 94 Tunisian sporadic breast carcinomas. Re...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.12.022
更新日期：2012-10-01 00:00:00
abstract：:Liver involvement in amyloidosis is rarely associated with intrahepatic cholestasis. The cases recorded in the literature indicate that there is a tendency toward periportal deposition, leading to centrilobular cholestasis. Our case was most interesting in that the amyloid deposition was most severe in the centrilobul...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(81)80029-9
更新日期：1981-05-01 00:00:00
abstract：:Plasmablastic lymphoma (PBL) of the oral cavity is classified as one subtype of diffuse large B-cell lymphoma that is most commonly seen in patients with human immunodeficiency virus infection. We report a rare case of PBL in the anal canal of a 33-year-old man with human immunodeficiency virus infection. The lymphoma...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2006.04.009
更新日期：2006-09-01 00:00:00
abstract：:Alterations of the epidermal growth factor receptor (EGFR) can be observed in a significant subset of esophageal adenocarcinomas (EACs), and targeted therapy against EGFR may become an interesting approach for the treatment of these tumors. Mutations of KRAS, NRAS, BRAF, and phosphatidylinositol-3-kinase catalytic sub...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2012.08.005
更新日期：2013-05-01 00:00:00
abstract：:Chondroblastoma (CBL) is a benign neoplasm of bone for which the genomic characteristics remain unclear. We compared the status of allelic losses of CBL with that seen in a set of chondrosarcomas (CS) to determine whether differences in their natural history and behavior are also reflected genetically. Eleven cases of...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2006.02.014
更新日期：2006-07-01 00:00:00
abstract：:Activated leukocyte cell adhesion molecule (CD166) is a member of the immunoglobulin superfamily and is aberrantly expressed in different tumors, including prostate cancer. To learn more on the prevalence and clinical significance of activated leukocyte cell adhesion molecule expression in prostate cancer, a tissue mi...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.02.017
更新日期：2011-12-01 00:00:00
abstract：:The cell of origin of parafollicular (monocytoid) B cell lymphoma (PBCL), splenic marginal zone lymphoma (SMZL), and hairy cell leukemia (HCL) is controversial. To better understand the relationship between these low-grade B-cell neoplasms, we analyzed the nucleotide sequences of the rearranged immunoglobulin heavy (I...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(99)90010-2
更新日期：1999-03-01 00:00:00
abstract：:Secretory carcinoma (SC) of the salivary gland is a low-grade malignancy associated with a well-defined clinical, histologic, immunohistochemical, and cytogenetic signature. Although the t(12;15) (p13;q25) translocation resulting in an ETV6-NTRK3 gene fusion is well documented, advances in molecular profiling in saliv...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.08.011
更新日期：2019-01-01 00:00:00
abstract：:Total parenteral nutrition (TPN) therapy is a well-recognized cause of liver injury. The histologic changes attributed to TPN in the literature vary widely. In this study, we describe the histopathologic changes associated with TPN therapy and relate these changes to various clinical parameters. We conducted a retrosp...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.07.008
更新日期：2012-06-01 00:00:00
abstract：:Recently, the fusion gene EML4-ALK was identified in non-small cell lung carcinoma, which could be a potential therapeutic target. We investigated the prevalence of anaplastic lymphoma kinase protein expression in these tumors by immunohistochemistry and correlated the results with data from ALK molecular studies. Gen...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2009.01.012
更新日期：2009-08-01 00:00:00
abstract：:Four human fetuses with the limb body wall malformation complex, also known as the amniotic band syndrome, were examined. Besides malformations of the body wall and the limb(s), anomalies of the internal organs were found in three fetuses, suggesting a disturbance of normal morphogenesis before the fifth week of devel...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(89)90225-6
更新日期：1989-11-01 00:00:00
abstract：:It has been proposed that an epithelial injury may be one of the multiple primary events in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The aim of this study was to characterize the tight junction and adherens junction proteins in normal human lung, IPF, cryptogenic organizing pneumonia, and asbestosis. W...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2012.08.016
更新日期：2013-05-01 00:00:00
abstract：:Five hundred eighty renal biopsies from a pool of 27850 archived cases were identified in which a myoglobin stain was performed because of atypical casts. Two hundred and thirty-eight (41%) of these biopsies were found to be positive for myoglobin casts. The morphology of the myoglobin casts ranged from light, almost ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2016.02.026
更新日期：2016-08-01 00:00:00
abstract：:We have previously reported that the drs gene has the ability to suppress transformation by v-src and v-K-ras in the rat cell line F2808. We have also shown that the expression of drs mRNA is markedly reduced in a variety of human cancer cell lines, suggesting that down-regulation of drs mRNA is correlated with the de...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(03)00240-5
更新日期：2003-07-01 00:00:00
abstract：:Epithelial-mesenchymal transition (EMT) plays a pivotal role in tumor invasion and metastasis in various malignancies. ZEB2/SIP1 is an important EMT regulator and down-regulates E-cadherin expression. The present study was planned to explore status of EMT-associated markers ZEB2/SIP1 and E-cadherin in eyelid sebaceous...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2015.05.026
更新日期：2015-10-01 00:00:00
abstract：:The diagnosis of metastatic adenocarcinoma to the brain of unknown primary is problematic, and the role of immunohistochemistry in identifying a source has not been fully characterized. Sixty-eight metastatic adenocarcinomas of the brain with known primaries were immunostained with antibodies to cytokeratin 7 (CK7), c...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(97)90009-5
更新日期：1997-08-01 00:00:00
abstract：:Twenty-one childhood rhabdomyosarcomas were divided into three groups on the basis of cytologic composition. The tumors in group P consisted entirely of primitive mesenchymal cells, whereas those in groups M and W were characterized by the additional presence of numerous round rhabdomyoblasts and strap cells, respecti...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(85)80256-2
更新日期：1985-08-01 00:00:00
abstract：:Three cases of primary thymic neuroendocrine tumors characterized by prominent angiomatoid features that resembled a vascular neoplasm are presented. The patients were all men between 52 and 59 years of age who presented with chest pain and shortness of breath attributable to a large anterior mediastinal mass. The les...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(99)90087-4
更新日期：1999-06-01 00:00:00
abstract：:Improved graft survival was observed in cadaver-kidney recipients prepared with random donor blood transfusions and in selected living-related-kidney recipients primed with transfusions from the kidney donor. This seems to justify a purposeful transfusion policy in these patients. ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(83)80031-8
更新日期：1983-03-01 00:00:00
abstract：:Pleomorphic adenomas of the breast (PAB) are uncommon tumors. We studied the clinicopathologic features of 10 cases of PAB, seven of which were assessed immunohistochemically. Nine patients were women, with a median age at diagnosis of 65 years. Eight patients presented with a palpable mass; two had a nipple discharge...
journal_title：Human pathology
pub_type： 杂志文章,评审
doi：10.1016/0046-8177(91)90102-u
更新日期：1991-12-01 00:00:00
abstract：:In retinoblastoma, genetic alteration of N-myc amplification different from the alteration of the RB1 gene on chromosome 13q14 has been described. This study is to determine the frequency of N-myc amplification by fluorescence in situ hybridization method in retinoblastoma. This study was prospectively derived from 26...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2007.12.008
更新日期：2008-08-01 00:00:00
abstract：:Nephronophthisis is an autosomal recessive tubulointerstitial nephropathy that is a leading genetic etiology of end-stage renal disease in children and young adults. Approximately 60% of patients with a known genetic etiology of nephronophthisis are due to homozygous deletion of the NPHP1 gene. We identified a total o...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.06.021
更新日期：2018-11-01 00:00:00
abstract：:Glial tumors of the retina are rare. Most are syndrome associated and include pilocytic astrocytoma in neurofibromatosis type 1 and subependymal giant cell astrocytoma in tuberous sclerosis complex. Acquired, more conventional, diffuse astrocytomas are less frequent. Ependymoma is exquisitely rare. Herein, we report t...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2008.06.028
更新日期：2009-04-01 00:00:00
abstract：:Malignant mixed tumors of the parotid gland are rare. Metastasizing lesions are even more rare. To the best of our knowledge, this is the first case reported in the English literature in which the scalp nodule was the primary manifestation of the malignant nature of the parotid tumor. ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(77)80100-7
更新日期：1977-11-01 00:00:00
abstract：:Epithelial inclusions in the axillary lymph nodes are very rare and have even less commonly been reported with either benign or malignant changes. We present a case of synchronous high-grade micropapillary ductal carcinoma in situ arising in the breast and in an epithelial inclusion in an ipsilateral sentinel lymph no...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2012.07.012
更新日期：2013-01-01 00:00:00
abstract：:A case of a tail in a 2-week-old infant is reported, and findings from a review of 33 previously reported cases of true tails and pseudotails are summarized. The true, or persistent, vestigial tail of humans arises from the most distal remnant of the embryonic tail. It contains adipose and connective tissue, central b...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(84)80079-9
更新日期：1984-05-01 00:00:00
abstract：:Acute myeloid leukemia is a heterogeneous group of diseases. Mutations of the isocitrate dehydrogenase (IDH) genes represent a novel class of point mutations in acute myeloid leukemia. These mutations prevent oxidative decarboxylation of isocitrate to α-ketoglutarate and confer novel enzymatic activity, facilitating t...
journal_title：Human pathology
pub_type： 杂志文章,评审
doi：10.1016/j.humpath.2012.05.003
更新日期：2012-10-01 00:00:00
abstract：:A rare example of melanoma arising in carcinoma ex pleomorphic adenoma is presented. The diagnosis, differential diagnosis, and putative histogenesis of the melanoma component are discussed. ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2010.12.002
更新日期：2011-09-01 00:00:00
abstract：:Peritoneal involvement in colorectal cancer (CRC) has prognostic significance and is an important parameter in pathologic tumor staging. Restaging of tumors based on peritoneal elastic lamina invasion (ELI) has prognostic significance in CRCs classified as pathologic stage 3 tumors without regional lymph node metastas...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.10.019
更新日期：2019-03-01 00:00:00
abstract：:Acute rejection is an extremely common complication of lung transplantation. (1) To appreciate the interobserver variation in the interpretation of histologic findings and (2) to assess the efficacy of transbronchial biopsy (TBB) for acute rejection diagnosis and associated diseases, particularly infection, we perform...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2005.01.022
更新日期：2005-04-01 00:00:00
