Juvenile granulosa cell tumor arising in ovarian adenosarcoma: an unusual form of sarcomatous overgrowth.

abstract：:T-prolymphocytic leukemia (T-PLL) is a rare mature T-cell neoplasm characterized by proliferation of prolymphocytes. Most cases involve the T-cell leukemia-1 (TCL1) gene at 14q11.2 resulting in overexpression of TCL-1, which is helpful for distinguishing T-PLL from other T-cell neoplasms. We report a patient with T-PL...

journal_title：Human pathology

authors： Hu Z,Li S,Medeiros LJ,Sun T

更新日期：2017-07-01 00:00:00

abstract：:A critical area of chromosomal loss at region p16(9p21-22) and p53(17p13) has been implicated in the genesis of malignant melanoma. It is still unclear whether the genetic alterations can be detected in dysplastic nevus, a premalignant lesion of malignant melanoma. We have searched the frequency of p16 and p53 deletio...

journal_title：Human pathology

authors： Park WS,Vortmeyer AO,Pack S,Duray PH,Böni R,Guerami AA,Emmert-Buck MR,Liotta LA,Zhuang Z

更新日期：1998-02-01 00:00:00

abstract：:Mucoepidermoid carcinoma of the breast is a rare entity with specific morphologic and immunohistochemical features similar to its salivary gland counterpart. In the 28 reported cases to date, there has not been a comparison of the molecular characteristics of this tumor with salivary gland mucoepidermoid carcinomas. H...

journal_title：Human pathology

authors： Camelo-Piragua SI,Habib C,Kanumuri P,Lago CE,Mason HS,Otis CN

更新日期：2009-06-01 00:00:00

abstract：:Interferon-induced protein with tetratricopeptide repeat 1 (IFIT1) plays a key role in growth suppression and apoptosis promotion in cancer cells. Interferon was reported to induce the expression of IFIT1 and inhibit the expression of O-6-methylguanine-DNA methyltransferase (MGMT).This study aimed to investigate the e...

journal_title：Human pathology

authors： Zhang JF,Chen Y,Lin GS,Zhang JD,Tang WL,Huang JH,Chen JS,Wang XF,Lin ZX

更新日期：2016-06-01 00:00:00

abstract：:Thoracoamniotic shunting is the treatment of choice for management of the fetus with type 1 congenital pulmonary airway malformation. Thoracoamniotic shunting has been performed to reduce life-threatening risks such as fetal hydrops. However, caution is needed because of possible complications. Here, we report that th...

journal_title：Human pathology

authors： Matsuoka K,Hayashi S,Urano F,Zhu LJ,Okita H,Sago H,Nakazawa A

更新日期：2012-09-01 00:00:00

abstract：:The introduction of next-generation sequencing has broadened the genetic landscape of myeloproliferative neoplasms (MPNs) beyond JAK2, MPL, and CALR. However, the biological role and clinical impact of most other mutations are not well defined. We interrogated 101 genes in 143 BCR-ABL1-negative MPNs in chronic phase f...

journal_title：Human pathology

authors： Boiocchi L,Hasserjian RP,Pozdnyakova O,Wong WJ,Lennerz JK,Le LP,Dias-Santagata D,Iafrate AJ,Hobbs GS,Nardi V

更新日期：2019-04-01 00:00:00

abstract：:This article reviews 281 malignant germ cell tumors of the ovary from the Armed Forces Institute of Pathology and highlights their distinctive clinical and pathologic features. Emphasis is placed on the importance of a combined therapeutic approach utilizing surgery, chemotherapy, and radiation. The rationale for unil...

journal_title：Human pathology

authors： Kurman RJ,Norris HJ

更新日期：1977-09-01 00:00:00

abstract：:Endolymphatic sac tumor (ELST) is a low-grade adenocarcinoma of the temporal bone that is presumed to originate from the endolymphatic system. Although ELSTs are extremely rare in the general population, a significant number of studies have documented the occurrence of ELST among patients with von Hippel-Lindau (VHL) ...

journal_title：Human pathology

authors： Hamazaki S,Yoshida M,Yao M,Nagashima Y,Taguchi K,Nakashima H,Okada S

更新日期：2001-11-01 00:00:00

abstract：:Paracoccidioidomycosis is a systemic mycosis with a geographic distribution that is limited to Central and South America; Brazil has the highest number of cases. Severe disseminated disease caused by paracoccidioidomycosis was observed in acquired immunodeficiency syndrome patients who live or have resided in endemic ...

journal_title：Human pathology

authors： de Freitas RS,Dantas KC,Garcia RS,Magri MM,de Andrade HF Jr

更新日期：2010-09-01 00:00:00

abstract：:The pathology of cytomegalovirus (CMV) encephalitis was studied at autopsy in thirty patients with acquired immunodeficiency syndrome. Lesions could be segregated into five major categories: microglial nodules, isolated inclusion-bearing cells, focal parenchymal necrosis, necrotizing ventriculo-encephalitis, and necro...

journal_title：Human pathology

authors： Morgello S,Cho ES,Nielsen S,Devinsky O,Petito CK

更新日期：1987-03-01 00:00:00

abstract：:In primary lung adenocarcinoma, EGFR and KRAS mutations are found in approximately 10% to 20% and 20% to 30%, respectively. Few studies have investigated these mutations in metastases. Patients with EGFR mutations have a 70% to 80% response rate to tyrosine-kinase inhibitors therapy and a longer progression-free survi...

journal_title：Human pathology

authors： Munfus-McCray D,Harada S,Adams C,Askin F,Clark D,Gabrielson E,Li QK

更新日期：2011-10-01 00:00:00

abstract：:The non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) are distinguished from classical papillary thyroid carcinoma with predominantly follicular architecture (CPTCPFA) by distinct histomorphologic and molecu...

journal_title：Human pathology

authors： Johnson DN,Sadow PM

更新日期：2018-12-01 00:00:00

abstract：:The epicardium contributes to cardiac formation, particularly during embryogenesis. It remains to be seen if it is also involved in postnatal myocardial homeostasis. This study evaluates the topographic distribution of stem cells (c-Kit) and extracardiac progenitor cells (CXCR4+) and their contribution to ventricular ...

journal_title：Human pathology

authors： Castellani C,Padalino M,China P,Fedrigo M,Frescura C,Milanesi O,Stellin G,Thiene G,Angelini A

更新日期：2010-11-01 00:00:00

abstract：:Sneddon's syndrome is a potentially fatal arterio-occlusive disorder characterized by generalized livedo racemosa and cerebrovascular lesions. Skin biopsies often fail to yield diagnostic arterial lesions. In the present series, affected vessels were found in skin biopsies from 12 of 15 patients with Sneddon's syndrom...

journal_title：Human pathology

authors： Zelger B,Sepp N,Schmid KW,Hintner H,Klein G,Fritsch PO

更新日期：1992-06-01 00:00:00

abstract：:Literature on BRCA1-associated protein 1 (BAP1) expression status in well-differentiated papillary mesothelioma (WDPM) is limited. In the present study, we examined the prevalence of BAP1 loss in WDPM by immunohistochemistry with clinical correlation, along with CDKN2A deletion status by fluorescence in situ hybridiza...

journal_title：Human pathology

authors： Lee HE,Molina JR,Sukov WR,Roden AC,Yi ES

更新日期：2018-09-01 00:00:00

abstract：:An increase in S100 protein-positive cells has been reported in inflammatory bowel diseases, mainly Crohn disease. These cells were interpreted as myeloid-derived dendritic cells, chiefly in follicular areas. We were prompted to assess the nature of these cells in interfollicular areas of inflamed colonic mucosa in ul...

journal_title：Human pathology

authors： Mosnier JF,Jarry A,Camdessanché JP,Antoine JC,Laboisse CL

更新日期：2009-08-01 00:00:00

abstract：:CD44 is an integral membrane glycoprotein that is a principal receptor for hyaluronan and plays a role in cell-extracellular matrix interactions. Recent studies of melanomas in mouse models have suggested that increased CD44 expression by these tumors may relate to metastatic potential. Immunohistochemical expression ...

journal_title：Human pathology

authors： Leigh CJ,Palechek PL,Knutson JR,McCarthy JB,Cohen MB,Argenyi ZB

更新日期：1996-12-01 00:00:00

abstract：:Clinicopathological studies of 181 patients with liver cirrhosis undergoing autopsy in the pathology department of a municipal hospital between 1973 and 1976 are reported. The main etiological types were alcoholic (25.4 per cent), HBsAg positive (14.9 per cent), and cryptogenic cirrhosis (54.7 per cent). Four patients...

journal_title：Human pathology

authors： Bartók I,Remenár,Tóth J,Duschanek P,Kanyár B

更新日期：1981-09-01 00:00:00

abstract：:The presence and morphology of high-grade prostatic intraepithelial neoplasia (H-PIN) was blindly evaluated in 40 totally embedded radical prostatectomy specimens of patients with prostate cancer randomized to either a 3 (n = 18) or 6 months (n = 22) combined androgen blockade regimen before surgery. In 5 cases, neo-a...

journal_title：Human pathology

authors： van der Kwast TH,Labrie F,Tetu B

更新日期：1999-12-01 00:00:00

abstract：:Four cases of radiation cystitis that caused diagnostic difficulty because of an epithelial proliferation with architectural complexity and reactive cytologic atypia are described. The patients, 2 male, 2 female, were from 43 to 77 years of age. Two presented with hematuria. Cystoscopy disclosed abnormalities in 3 pat...

journal_title：Human pathology

authors： Baker PM,Young RH

更新日期：2000-06-01 00:00:00

abstract：:Adamantinoma of the long bones is a rare, typically low-grade malignant tumor that frequently involves the tibia. Radiographically, adamantinoma is characteristically a lytic, intracortical, and expansile lesion with variable margins. Histologically, adamantinoma is a bimorphic neoplasm, composed of epithelial and ost...

journal_title：Human pathology

authors： Dashti NK,Howe BM,Inwards CY,Fritchie KJ,Carter JM

更新日期：2019-09-01 00:00:00

abstract：:Fibrillar proteins with a role in cellular shape and motility are present in the cytoplasm of most animal cells. They vary greatly in size, organization, and reactivity according to cell type and can be separately identified by the use of recently developed monospecific antisera and indirect immunofluorescence stainin...

journal_title：Human pathology

authors： Sieinski W,Dorsett B,Ioachim HL

更新日期：1981-05-01 00:00:00

abstract：:Current regulations require that departments of pathology have a structured and active program of quality assurance (QA) and quality improvement (QI), with the goals of enhancing patient safety, minimizing error, ensuring timely delivery of reports, and monitoring physician competence. Types of potential error may evo...

journal_title：Human pathology

authors： Association Of Directors Of Anatomic And Surgical Pathology.,Nakhleh R,Coffin C,Cooper K

更新日期：2006-08-01 00:00:00

abstract：:Clinicopathologic records and neuropathologic tissues of 109 patients who underwent necropsy after treatment with bone marrow transplantation (BMT) were examined. Underlying disorders included leukemia (70), aplastic anemia (25), solid tumors (7), lymphoma (5), Hodgkin's disease (1) and Wiskott-Aldrich syndrome (1). T...

journal_title：Human pathology

authors： Mohrmann RL,Mah V,Vinters HV

更新日期：1990-06-01 00:00:00

abstract：:The synovium in two well-documented cases of alkaptonuric ochronosis was studied by transmission electron and light microscopy. A feature of alkaptonuria previously unreported in the English-language literature was the presence of phagocytosis of large collagen fibrils by synovial macrophages in both cases. The origin...

journal_title：Human pathology

authors： Gaines JJ Jr,Tom GD,Khankhanian N

更新日期：1987-11-01 00:00:00

abstract：:Activating transcription factor 3, a member of the activating transcription factor/cyclic adenosine monophosphate response element-binding family of transcription factors, is an adaptive response gene that plays an oncogenic role in the development of various cancers. To our knowledge, few information are available on...

journal_title：Human pathology

authors： Kim MS,In SG,Park OJ,Won CH,Lee MW,Choi JH,Kim CW,Kim SE,Moon KC,Chang S

更新日期：2011-07-01 00:00:00

abstract：:Five hundred consecutive breast carcinomas from the first screening round of the Breast Cancer Detection Demonstration Project were studied quantitatively and semiquantitatively for features relevant to the diagnosis of tubular carcinoma. Tubularity was defined as the proportion of tumor cells that were adjacent to an...

journal_title：Human pathology

authors： Stalsberg H,Hartmann WH

更新日期：2000-05-01 00:00:00

abstract：:Four surgically resected cardiac valves received from three female patients showed the presence of acute and chronic rheumatic valvulitis. The material was studied by means of transmission and scanning electron microscopy. This is the first time that there has been an investigation of the ultrastructure in acute rheum...

journal_title：Human pathology

authors： Siew S

更新日期：1980-01-01 00:00:00

abstract：:Endometrial carcinoma is the most common invasive malignancy of the female genital tract, and it exists as two different clinicopathologic forms: an estrogen-dependent, "usual" type and an estrogen-independent "special variant" type. Despite the frequency of endometrial cancer, little is known about the molecular gene...

journal_title：Human pathology

authors： Tritz D,Pieretti M,Turner S,Powell D

更新日期：1997-05-01 00:00:00

abstract：:We have previously reported that the drs gene has the ability to suppress transformation by v-src and v-K-ras in the rat cell line F2808. We have also shown that the expression of drs mRNA is markedly reduced in a variety of human cancer cell lines, suggesting that down-regulation of drs mRNA is correlated with the de...

journal_title：Human pathology

authors： Kim CJ,Shimakage M,Kushima R,Mukaisho K,Shinka T,Okada Y,Inoue H

更新日期：2003-07-01 00:00:00