Non-Hodgkin's lymphoma, multilobated B-cell type: report of nine cases with immunohistochemical and immunoultrastructural evidence for a follicular center cell derivation.

abstract：:Except for post-transfusion hepatitis (PTH), the transmission of disease by blood transfusion appears to be very limited. There are only a few case reports documenting the transmission of malaria and other parasitic diseases, syphilis, or bacterial infections. The ability to eradicate PTH will depend on the developmen...

journal_title：Human pathology

authors： Kahn RA

更新日期：1983-03-01 00:00:00

abstract：:Tumor budding is an acknowledged prognostic marker in colorectal cancer. This study was conducted to investigate the morphology and prognostic significance of budding in rectal cancer after neoadjuvant radiotherapy. Surgical specimens from 96 consecutive patients who underwent neoadjuvant radiotherapy and curative res...

journal_title：Human pathology

authors： Du C,Xue W,Li J,Cai Y,Gu J

更新日期：2012-07-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a rare disease which afflicts young women of childbearing age. Recently, it has been listed as an indication for lung transplantation. We describe a case of recurrent LAM in a 31-year-old woman occurring in the allograft of a male donor after single lung transplantation. Nonisotopic i...

journal_title：Human pathology

authors： Bittmann I,Dose TB,Müller C,Dienemann H,Vogelmeier C,Löhrs U

更新日期：1997-12-01 00:00:00

abstract：:After endoscopic resection of early gastric cancer (EGC), it is imperative to accurately determine whether follow-up surgery is indicated, since this technique is used as a first line of treatment. Herein, we developed a scoring system to indicate the risk of lymph node metastasis in submucosal EGC (smEGC), and presen...

journal_title：Human pathology

authors： Kim JY,Kim WG,Jeon TY,Kim GH,Jeong EH,Kim DH,Park DY,Lauwers GY

更新日期：2013-12-01 00:00:00

abstract：:This study aims to develop a prediction model for spontaneous regression of cervical intraepithelial neoplasia grade 2 (CIN 2) lesions based on simple clinicopathological parameters. The study was conducted at Maastricht University Medical Center, the Netherlands. The prediction model was developed in a retrospective ...

journal_title：Human pathology

authors： Koeneman MM,van Lint FHM,van Kuijk SMJ,Smits LJM,Kooreman LFS,Kruitwagen RFPM,Kruse AJ

更新日期：2017-01-01 00:00:00

abstract：:Immunofluorescence of formalin-fixed, paraffin-embedded tissues was performed to study the plasma cell population in 114 colonic specimens from 58 patients. Correlation of the histopathologic stage of disease activity with the isotypes and numbers of immunoglobulin-containing cells in the lamina propria demonstrated h...

journal_title：Human pathology

authors： Keren DF,Appelman HD,Dobbins WO 3rd,Wells JJ,Whisenant B,Foley J,Dieterle R,Geisinger K

更新日期：1984-08-01 00:00:00

abstract：:Adamantinoma of the long bones is a rare, typically low-grade malignant tumor that frequently involves the tibia. Radiographically, adamantinoma is characteristically a lytic, intracortical, and expansile lesion with variable margins. Histologically, adamantinoma is a bimorphic neoplasm, composed of epithelial and ost...

journal_title：Human pathology

authors： Dashti NK,Howe BM,Inwards CY,Fritchie KJ,Carter JM

更新日期：2019-09-01 00:00:00

abstract：:Adamantinoma of long bones is a rare skeletal tumor of unknown origin with epithelial and fibrous elements. The ill-defined distinction between the two components in some cases earlier led to the assumption that these might be derived from the same (mesenchymal) stem cell. In this study, we investigated the distributi...

journal_title：Human pathology

authors： Hazelbag HM,Van den Broek LJ,Fleuren GJ,Taminiau AH,Hogendoorn PC

更新日期：1997-02-01 00:00:00

abstract：:Histone methyltransferase (HMT), which catalyzes a histone methylation, is frequently altered in cancers at mutation and expression levels. The aims of this study were to explore whether SETD1B, SETDB2, and SETD2, SET domain-containing HMT genes, are mutated and expressionally altered in gastric (GC) and colorectal ca...

journal_title：Human pathology

authors： Choi YJ,Oh HR,Choi MR,Gwak M,An CH,Chung YJ,Yoo NJ,Lee SH

更新日期：2014-08-01 00:00:00

abstract：:We describe a case of simultaneous nodular sclerosing Hodgkin's disease and a granulocytic sarcoma in a cervical lymph node without any previous therapy. The condition evolved into acute myelogenous leukemia approximately 8 months after the initial diagnosis of the granulocytic sarcoma. The unexpected presence of a gr...

journal_title：Human pathology

authors： Suh YK,Shin SS,Koo CH

更新日期：1996-10-01 00:00:00

abstract：:The clinical spectrum of coronavirus disease 2019 is getting wider with the exponential increase of patients worldwide. Initially described with flu-like symptoms, variable cutaneous manifestations have been reported, with only few histopathological descriptions. Detection of the virus in cutaneous samples has been as...

journal_title：Human pathology

authors： Fattori A,Cribier B,Chenard MP,Mitcov M,Mayeur S,Weingertner N

更新日期：2021-01-01 00:00:00

abstract：:Overexpression of mitotic arrest deficient 2 (MAD2) and/or cell division cycle 20 (CDC20) in the spindle assembly checkpoint leads to chromosomal instability and aneuploidy. Cell-in-cell (CIC) structures are formed by the process where cancer or immune cells are internalized into adjacent host cancer cells. Here, we i...

journal_title：Human pathology

authors： Kim Y,Choi JW,Lee JH,Kim YS

更新日期：2019-03-01 00:00:00

abstract：:Bioassay of hormones has a small but important role in defining the physiologic status of selected patients in whom immunoassay results do not correlate with clinical signs and symptoms. This article reviews three sensitive bioassays for hormones, which are based on 1) stimulation of adenylate cyclase in membrane prep...

journal_title：Human pathology

authors： Klee GG

更新日期：1984-02-01 00:00:00

abstract：:A 61-year-old white woman was found to have disseminated abdominal carcinoma at autopsy. The primary site proved to be a bile duct carcinoma arising from ductal epithelium of multiple von Meyenburg complexes of the liver. No other neoplastic lesion was found elsewhere after careful, gross, microscopic examination. Thi...

journal_title：Human pathology

authors： Honda N,Cobb C,Lechago J

更新日期：1986-12-01 00:00:00

abstract：:Viruses and other possible causative agents should be sought light and electron microscopically in all cases of ill-defined diseases including "sarcoid." Ideally, tissue should be prepared for electron microscopic examination as soon as a specimen is obtained; however, when this has not been done, tissue preserved in ...

journal_title：Human pathology

authors： Wang NS

更新日期：1983-10-01 00:00:00

abstract：:Glypican 3 is a heparin sulfate proteoglycan bound to the cell surface that is theorized to participate in cell signaling, resulting in embryonic cell growth and differentiation. The GPC3 gene is mutated in Simpson-Golabi-Behmel syndrome, whose features include numerous developmental abnormalities, tissue overgrowth, ...

journal_title：Human pathology

authors： Zynger DL,Gupta A,Luan C,Chou PM,Yang GY,Yang XJ

更新日期：2008-02-01 00:00:00

abstract：:In 1999, the World Health Organization (WHO) published a new classification of papillary urothelial tumors of the urinary bladder. Intended to represent a reproducible, easy-to-use classification system that better separates patients with true malignancies (bladder cancer) from those patients who are at an increased r...

journal_title：Human pathology

authors： Helpap B,Köllermann J

更新日期：2000-06-01 00:00:00

abstract：:The pathogenesis of lacaziosis continues to be obscure, and works have investigated the blood systemic immune response or the dermal immune response in restricted lesions in different body regions. Some authors describe that the inflammatory infiltrate in lacaziosis lesions showed a predominance of macrophages followe...

journal_title：Human pathology

authors： Oliveira Carneiro FR,da Cunha Fischer TR,Brandão CM,Pagliari C,Duarte MI,Quaresma JA

更新日期：2015-02-01 00:00:00

abstract：:In a prior study we reported that monotypic immunoglobulin expression significantly correlated with an increased risk of dissemination by small lymphocytic infiltrates (SLIs) of the orbit and conjunctiva. However, less than half of all monotypic SLIs disseminated. In this study, we applied a large panel of monoclonal ...

journal_title：Human pathology

authors： Medeiros LJ,Harris NL

更新日期：1990-11-01 00:00:00

abstract：:In the past few years many clinically significant new glomerular lesions have been reported from observations made on renal biopsy specimens by electron microscopy. The clinical applicability of electron microscopy is illustrated by examples of specific ultrastructural patterns of glomerular reaction making possible a...

journal_title：Human pathology

authors： Spargo BH

更新日期：1975-07-01 00:00:00

abstract：:Inflammatory bowel disease-associated colorectal carcinomas (IBD-CRCs) develop in a background of chronic inflammation, and thus, the molecular landscape of these tumors likely differs from that of sporadic colorectal cancer. To add to emerging data on molecular alterations present in these tumors, we analyzed our ins...

journal_title：Human pathology

authors： Alpert L,Yassan L,Poon R,Kadri S,Niu N,Patil SA,Mujacic I,Montes D,Galbo F,Wurst MN,Zhen CJ,Cohen RD,Rubin DT,Pekow JR,Weber CR,Xiao SY,Hart J,Segal J,Setia N

更新日期：2019-07-01 00:00:00

abstract：:GATA-3 and estrogen receptor (ER) are involved in a positive cross-regulatory loop and are frequently coexpressed in breast cancers. GATA-3 expression was shown to be an independent predictor of overall and disease-free survival in some studies, whereas others showed no difference. However, the studies used different ...

journal_title：Human pathology

authors： Gulbahce HE,Sweeney C,Surowiecka M,Knapp D,Varghese L,Blair CK

更新日期：2013-11-01 00:00:00

abstract：:A solitary fibrous tumor (SFT) is a rare, NAB2-STAT6 fusion gene-associated mesenchymal neoplasm. It most commonly arises in the pleural site, but it can occur at many other sites, and rarely also in the head and neck (H&N) region. STFs may show many growth patterns and therefore can be easily mistaken for other more ...

journal_title：Human pathology

authors： Baněčková M,Martínek P,Skálová A,Mezencev R,Hadravský L,Michal M,Švajdler M

更新日期：2020-05-01 00:00:00

abstract：:The very late antigens (VLAs) are alpha beta-heterodimeric transmembrane proteins that include surface cell receptors for laminin (VLA-6) and collagen (VLA-2), which mediate cell-matrix and cell-cell adhesion. We investigated the distribution of VLA-6 (alpha 6, beta 1) and VLA-2 (alpha 2, beta 1) proteins in normal, h...

journal_title：Human pathology

authors： Bonkhoff H,Stein U,Remberger K

更新日期：1993-03-01 00:00:00

abstract：:The SHH signaling pathway is critical for gastrointestinal development and organic patterning, and dysregulation of SHH pathway molecules has been detected in multiple gastrointestinal neoplasms. This study investigated the role of the SHH signaling pathway in PJS. Expression of SHH, PTCH, and GLI1 was examined by rea...

journal_title：Human pathology

authors： Xu X,Su J,Li R,Wang Y,Zeng D,Wu B

更新日期：2016-04-01 00:00:00

abstract：:Glial tumors of the retina are rare. Most are syndrome associated and include pilocytic astrocytoma in neurofibromatosis type 1 and subependymal giant cell astrocytoma in tuberous sclerosis complex. Acquired, more conventional, diffuse astrocytomas are less frequent. Ependymoma is exquisitely rare. Herein, we report t...

journal_title：Human pathology

authors： Tay A,Scheithauer BW,Cameron JD,Myhre MJ,Boerner MJ

更新日期：2009-04-01 00:00:00

abstract：:Endometrioid endometrial carcinomas (EECs) are correlated with high serum levels of androgens and estrogen. We hypothesized that Leydig cells and ovarian stromal hyperplasia contribute to postmenopausal ovarian androgen production and are observed more frequently in EEC patients. Ovaries of postmenopausal women with E...

journal_title：Human pathology

authors： Reijnen C,Küsters-Vandevelde HVN,Abbink K,Zusterzeel PLM,van Herwaarden AE,van der Laak JAWM,Massuger LFAG,Snijders MPLM,Pijnenborg JMA,Bulten J

更新日期：2019-03-01 00:00:00

abstract：:Esophageal cancer is one of the most fatal cancers worldwide and is characterized by great variation in rates among different populations. Linxian, a county in Henan Province, located in north-central China, has one of the highest rates of esophageal squamous cell carcinoma in the world. Most squamous cell carcinomas ...

journal_title：Human pathology

authors： Roth MJ,Guo-Qing W,Lewin KJ,Ning L,Dawsey SM,Wesley MN,Giffen C,Yong-Qiang X,Maher MM,Taylor PR

更新日期：1998-11-01 00:00:00

abstract：:Differentiation features and proliferation activity of 67 gastric microleiomyomas (microLMs) and 53 clinical gastrointestinal stromal tumors (GISTs) of the stomach were compared. The 67 microLMs were divided into two categories on the basis of cellularity: 53 hypocellular and 14 hypercellular types, and the 39 GISTs w...

journal_title：Human pathology

authors： Mikami T,Terada T,Nakamura K,Okayasu I

更新日期：1997-12-01 00:00:00

abstract：:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) generally confers poor prognosis; however, the clinical outcome remains heterogeneous. We sought to further stratify this subentity of AML by performing a retrospective analysis of 179 adult patients with AML-MRC diagnosed at our institution. Based o...

journal_title：Human pathology

authors： Jiang G,Capo-Chichi JM,Liu A,Atenafu EG,Guo R,Tierens A,Minden MD,Chang H

更新日期：2020-10-01 00:00:00