Correlation of histopathologic evidence of disease activity with the presence of immunoglobulin-containing cells in the colons of patients with inflammatory bowel disease.

abstract：:This report describes a 47-year-old man with Erdheim-Chester disease (EC), the second case reported in Japan. The patient complained of knee pain, and the roentgenogram of the bilateral legs revealed symmetric osteolytic lesions with sclerosis of the metaphyseal regions of the long bones. Histological examination of t...

journal_title：Human pathology

authors： Ono K,Oshiro M,Uemura K,Ota H,Matsushita Y,Ijima S,Iwase T,Uchida M,Katsuyama T

更新日期：1996-01-01 00:00:00

abstract：:Lung cancer has always been the leading cause of death among patients with malignant tumors, and the majority of these patients die because of cancer cell invasion and metastasis. Previous studies have implicated coiled-coil domain-containing protein 8 (CCDC8) as a tumor suppressor in several types of cancer, such as ...

journal_title：Human pathology

authors： Jiang GY,Zhang XP,Zhang Y,Xu HT,Wang L,Li QC,Wang EH

更新日期：2016-10-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is an angiogenic factor that plays important roles in tumor growth. Angiogenesis studies on VEGF deal with various types of malignant tumors, but very little is known about the role or significance of VEGF in human thyroid neo...

journal_title：Human pathology

authors： Katoh R,Miyagi E,Kawaoi A,Hemmi A,Komiyama A,Oyama T,Shibuya M

更新日期：1999-08-01 00:00:00

abstract：:Kearns-Sayre syndrome (KSS) and Pearson's marrow-pancreas syndrome (PMPS) are rare disorders caused by the same molecular defect, one of several deletion mutations in mitochondrial DNA (mtDNA). KSS is an encephalomyopathy with ophthalmoplegia, retinal degeneration, ataxia, and endocrine abnormalities. PMPS is a disord...

journal_title：Human pathology

authors： Becher MW,Wills ML,Noll WW,Hurko O,Price DL

更新日期：1999-05-01 00:00:00

abstract：:The molecular pathology of 20 lymphomas, which presented as testicular masses in patients with no evidence of previous lymphoma, was analyzed. These lymphomas occurred in men with a median age of 69 years (range, 37 to 87 years). Nine of the 14 patients with follow-up died of lymphoma (median survival, 12 months). All...

journal_title：Human pathology

authors： Hyland J,Lasota J,Jasinski M,Petersen RO,Nordling S,Miettinen M

更新日期：1998-11-01 00:00:00

abstract：:Kikuchi's histiocytic necrotizing lymphadenitis is a self-limited disorder that typically involves the cervical lymph nodes of young women. Although a viral etiology has been postulated, a definitive viral agent has not been identified. Recent reports have suggested that human herpesvirus 8 (HHV 8) or Epstein-Barr vir...

journal_title：Human pathology

authors： George TI,Jones CD,Zehnder JL,Warnke RA,Dorfman RF

更新日期：2003-02-01 00:00:00

abstract：:Human immunodeficiency virus-associated nephropathy (HI-VAN) is a common form of nephropathy present in HIV-infected individuals that clinically presents with proteinuria that is frequently in the nephrotic range, less often with hematuria, and with a course that may evolve to irreversible azotemia ultimately resultin...

journal_title：Human pathology

authors： Rey L,Viciana A,Ruiz P

更新日期：1995-04-01 00:00:00

abstract：:Previous studies have found a link between high expression levels of the Deleted in Split hand/Split foot 1 (DSS1) gene and cancer progression. The aim of this study was to examine whether overexpression of DSS1 is a feature of melanoma and squamous cell carcinoma (SCC) and if any epigenetic modifications are involved...

journal_title：Human pathology

authors： Venza M,Visalli M,Catalano T,Beninati C,Teti D,Venza I

更新日期：2017-02-01 00:00:00

abstract：:In order to study the granular transformation of Sertoli cells the following testicular specimens were reviewed: 58 postmortem biopsies from 21 children and 37 young adult males with normal histologic pattern; 165 biopsies from prepubertal cryptorchid testes; 38 biopsies and 18 surgical specimens from postpubertal-cry...

journal_title：Human pathology

authors： Nistal M,Garcia-Rodeja E,Paniagua R

更新日期：1991-02-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a group of granulomatous disorders in which abnormal Langerhans cells proliferate as either a localized lesion in a single bone or disseminated disease involving two or more organs or systems. Because the different LCH forms exhibit significantly elevated levels of inflammatory m...

journal_title：Human pathology

authors： Murakami I,Matsushita M,Iwasaki T,Kuwamoto S,Kato M,Horie Y,Hayashi K,Imamura T,Morimoto A,Imashuku S,Gogusev J,Jaubert F,Takata K,Oka T,Yoshino T

更新日期：2014-01-01 00:00:00

abstract：:Malignant peripheral nerve sheath tumor is a malignant tumor showing nerve sheath differentiation. Approximately one-half of malignant peripheral nerve sheath tumors arise from a benign peripheral nerve sheath tumor, which is commonly a neurofibroma in patients with neurofibromatosis type 1. Malignant peripheral nerve...

journal_title：Human pathology

authors： Endo M,Yamamoto H,Harimaya K,Kohashi K,Ishii T,Setsu N,Iwamoto Y,Oda Y

更新日期：2013-12-01 00:00:00

abstract：:ATP-binding cassette (ABC) multidrug transporters have been associated with chemoresistance, which is a major obstacle in attempts to improve clinical outcome of patients with nasopharyngeal carcinoma (NPC). In this study, we investigated 3 ABC multidrug transporters including MDR1, MRP1, and BCRP for their potential ...

journal_title：Human pathology

authors： Larbcharoensub N,Leopairat J,Sirachainan E,Narkwong L,Bhongmakapat T,Rasmeepaisarn K,Janvilisri T

更新日期：2008-06-01 00:00:00

abstract：:Digitization of histologic slides is associated with many advantages, and its use in routine diagnosis holds great promise. Nevertheless, few articles evaluate virtual microscopy in routine settings. This study is an evaluation of the validity and diagnostic performance of virtual microscopy in routine histologic diag...

journal_title：Human pathology

authors： Nielsen PS,Lindebjerg J,Rasmussen J,Starklint H,Waldstrøm M,Nielsen B

更新日期：2010-12-01 00:00:00

abstract：:The histone methyltransferase G9a (EHMT2) is a key enzyme for dimethylation of lysine 9 at histone 3 (H3K9me2), a suppressive epigenetic mark. G9a is over-expressed in tumor cells and contributes to cancer aggressiveness. Biliary tract cancer (BTC) is a rare cancer with dismal prognosis due to a lack of effective ther...

journal_title：Human pathology

authors： Mayr C,Helm K,Jakab M,Ritter M,Shrestha R,Makaju R,Wagner A,Pichler M,Beyreis M,Staettner S,Jaeger T,Klieser E,Kiesslich T,Neureiter D

更新日期：2018-02-01 00:00:00

abstract：:Insulin-like growth factor-II messenger RNA-binding protein 3 (IGF2BP3 or IMP3) is a biomarker whose expression has been found to be a negative prognostic factor in several neoplasms including ovarian clear cell carcinoma (CCC). In this study, we analyzed the frequency and clinicopathologic significance of IMP3 expres...

journal_title：Human pathology

authors： Fadare O,Liang SX,Crispens MA,Jones HW 3rd,Khabele D,Gwin K,Zheng W,Mohammed K,Parkash V,Hecht JL,Desouki MM

更新日期：2013-08-01 00:00:00

abstract：:Among 448 malignant epithelial tumors of the gallbladder, 19 were classified as oat cell carcinomas. Seventeen cases occurred in elderly women. Eighteen of the patients had cholelithiasis. The neoplasms were highly lethal, metastasizing early and causing death shortly after diagnosis. All 19 patients died as a direct ...

journal_title：Human pathology

authors： Albores-Saavedra J,Soriano J,Larraza-Hernandez O,Aguirre J,Henson DE

更新日期：1984-07-01 00:00:00

abstract：:Colonic adenocarcinomas are among the most common type of tumors. In this report, we present the morphologic, immunohistochemical, and microsatellite findings of 2 cases with a distinct invasive papillary component. Both tumors arose from polyps in middle-aged patients, followed an aggressive course, and showed a supe...

journal_title：Human pathology

authors： Palazzo JP,Edmonston TB,Chaille-Arnold LM,Burkholder S

更新日期：2002-03-01 00:00:00

abstract：:Nested urothelial carcinoma (UC) is a rare histologic variant of UC, characterized by deceptively bland histologic features resembling von Brunn's nests but usually with a poor outcome. In our experience, this variant is frequently misclassified or underrecognized as its clinicopathologic spectrum is not well defined....

journal_title：Human pathology

authors： Wasco MJ,Daignault S,Bradley D,Shah RB

更新日期：2010-02-01 00:00:00

abstract：:Pityriasis lichenoides (PL) is a papulosquamous disorder often considered a form of reactive dermatosis and classified with small plaque parapsoriasis (digitate dermatosis). However, some patients with PL have developed large plaque parapsoriasis (LPP) and mycosis fungoides (MF), and lymphoid atypia and T-cell clonali...

journal_title：Human pathology

authors： Magro C,Crowson AN,Kovatich A,Burns F

更新日期：2002-08-01 00:00:00

abstract：:Autopsy studies of three premature siblings who died soon after birth with the neonatal myotonic dystrophy syndrome revealed pulmonary hypoplasia and congenital pleural effusions. Neither of these findings has been described previously in this condition. New ultrastructural findings include focal diaphragmatic myofibe...

journal_title：Human pathology

authors： Silver MM,Vilos GA,Silver MD,Shaheed WS,Turner KL

更新日期：1984-12-01 00:00:00

abstract：:Pulmonary inflammatory pseudotumors (IP) are rare mesenchymal proliferations that have a polymorphic histology and an unpredictable biologic behavior. The histologic spectrum of IP has led to uncertainty as to whether this tumor has a reactive or neoplastic pathogenesis. Reports of extrapulmonary IP have identified cl...

journal_title：Human pathology

authors： Yousem SA,Shaw H,Cieply K

更新日期：2001-04-01 00:00:00

abstract：:The authors report an unusual case of in situ follicular lymphoma associated with progressive transformation of the germinal centers. The patient was a 74-year-old Chinese woman with sequential lymphadenopathy in the right and left cervical regions over a period of 2 months. The first biopsy revealed in situ follicula...

journal_title：Human pathology

authors： Li JN,Zhang WY,Tang Y,Li GD,Dong DD

更新日期：2012-01-01 00:00:00

abstract：:Women with breast cancer have an increased risk of developing primary ovarian tumors. Because a differential diagnosis between primary and metastatic tumors may be difficult in poorly differentiated ovarian neoplasms, breast carcinoma markers may be helpful in establishing the primary site of origin. Gross cystic dise...

journal_title：Human pathology

authors： Monteagudo C,Merino MJ,LaPorte N,Neumann RD

更新日期：1991-04-01 00:00:00

abstract：:Glomerulonephritis (GN) characterized by immune complex deposits typical of postinfectious GN but with a paucity or absence of overt clinical symptoms and/or urinary abnormalities may occur after a group A streptococcus infection. The overall incidence of this type of subclinical GN is not known. To address this quest...

journal_title：Human pathology

authors： Haas M

更新日期：2003-01-01 00:00:00

abstract：:Isolated submandibular adenopathy developed in a patient who had subacute erythroleukemia. Lymph node biopsy revealed a proliferation of immature cells and scattered foci of dyserythropoietic normoblasts. Since a review of the literature revealed no detailed description of an erythroleukemic lymph node infiltrate, a h...

journal_title：Human pathology

authors： Keifer J,Zaino R,Ballard JO

更新日期：1984-11-01 00:00:00

abstract：:Histopathologic lesions in the central nervous system (CNS) of 400 autopsy cases of the acquired immunodeficiency syndrome (AIDS) collected from 1982 to 1990 were studied. Lesions most closely associated with human immunodeficiency virus (HIV) infection in the CNS (perivascular macrophages, nodular encephalomyelitis, ...

journal_title：Human pathology

authors： Rhodes RH

更新日期：1993-11-01 00:00:00

abstract：:Most ovarian sex cord-stromal tumors (SCSTs) can be categorized on the basis of conventional histology, but approximately 10% of cases are unclassified because they present indeterminate or overlapping morphologic features. Immunohistochemical and molecular studies of unclassified ovarian SCST are very limited, but re...

journal_title：Human pathology

authors： Stewart CJ,Alexiadis M,Crook ML,Fuller PJ

更新日期：2013-12-01 00:00:00

abstract：:Hemangiopericytoma and fibrosarcoma represented at one time two of the most common diagnoses in soft tissue pathology. Both terms are now largely extinct. This article will review the clinicopathologic, immunohistochemical and molecular genetic advances that have led to these changes, and review the pathologic feature...

journal_title：Human pathology

authors： Folpe AL

更新日期：2020-01-01 00:00:00

abstract：:Neuronal intranuclear inclusion disease (NIID) is a progressive, usually fatal degenerative neurologic condition characterized by eosinophilic, intranuclear inclusions in neurons of the central and peripheral nervous system. We report a boy with onset of disease manifestations at age 3 and death at age 9, who showed c...

journal_title：Human pathology

authors： Oyer CE,Cortez S,O'Shea P,Popovic M

更新日期：1991-07-01 00:00:00

abstract：:We examined the infection of herpes simplex virus (HSV), human cytomegalovirus (HCMV), and Epstein-Barr virus (EBV) in 61 autopsy cases with secondary diffuse interstitial pneumonia (SDIP) by immunohistochemistry and compared our findings with those in 46 individuals without lung complications. There was no significan...

journal_title：Human pathology

authors： Oda Y,Okada Y,Katsuda S,Nakanishi I

更新日期：1994-10-01 00:00:00