Role of biopersistence in the pathogenicity of man-made fibers and methods for evaluating biopersistence: a summary of two round-table discussions.

abstract：:Rates of developmental and respiratory diseases are disproportionately high in underserved, minority populations such as those in New York City's Washington Heights, Harlem, and the South Bronx. Blacks and Latinos in these neighborhoods represent high risk groups for asthma, adverse birth outcomes, impaired developmen...

journal_title：Environmental health perspectives

authors： Perera FP,Illman SM,Kinney PL,Whyatt RM,Kelvin EA,Shepard P,Evans D,Fullilove M,Ford J,Miller RL,Meyer IH,Rauh VA

更新日期：2002-02-01 00:00:00

abstract：:Attention has been focussed, both in man and experimental animals, on the effects of inhalation of the gas monomer, vinyl chloride. Recently, note is being taken of the possible effects of the inhalation of the polymer in man. The particles in question are those produced commercially as paste polymer or dispersion pol...

journal_title：Environmental health perspectives

authors： Wagner JC,Johnson NF

更新日期：1981-10-01 00:00:00

abstract：:Collaborative studies were performed to develop a functional assay for fish-killing activity produced by Pfiesteria piscicida. Eight cell lines were used to screen organic fractions and residual water fraction by using a 3-[4, 5-dimethylthiazol-(2-4)]-diphenyltetrazolium bromide cytotoxicity assay. Diethyl ether and a...

journal_title：Environmental health perspectives

authors： Fairey ER,Edmunds JS,Deamer-Melia NJ,Glasgow H Jr,Johnson FM,Moeller PR,Burkholder JM,Ramsdell JS

更新日期：1999-09-01 00:00:00

abstract：:The progression of the cell cycle is controlled by the action of both positive and negative growth regulators. The key players in this activity include a family of cyclins and cyclin-dependent kinases, which are themselves regulated by other kinases and phosphatases. Maintenance of balanced cell cycle controls may be ...

journal_title：Environmental health perspectives

authors： Afshari CA,Barrett JC

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Organophosphates elicit developmental neurotoxicity through multiple mechanisms other than their shared property as cholinesterase inhibitors. Accordingly, these agents may differ in their effects on specific brain circuits. OBJECTIVES:We gave parathion to neonatal rats [postnatal days (PNDs) 1-4], at daily...

journal_title：Environmental health perspectives

authors： Slotkin TA,Bodwell BE,Ryde IT,Levin ED,Seidler FJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Increasing evidence suggests a proatherogenic role for lipoprotein-associated phospholipase A₂ (Lp-PLA2). A meta-analysis of published cohorts has shown that Lp-PLA2 is an independent predictor of coronary heart disease events and stroke. OBJECTIVE:In this study, we investigated whether the association betw...

journal_title：Environmental health perspectives

authors： Brüske I,Hampel R,Baumgärtner Z,Rückerl R,Greven S,Koenig W,Peters A,Schneider A

更新日期：2011-07-01 00:00:00

abstract：:In vitro liver preparations are increasingly used for the study of hepatotoxicity of chemicals. In recent years their actual advantages and limitations have been better defined. The cell models, slices, and mainly primary hepatocyte cultures, appear to be the most powerful in vitro systems, as liver-specific functions...

journal_title：Environmental health perspectives

authors： Guillouzo A

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:The widespread use of organophosphorus (OP) pesticides has led to frequent exposure in adults and children. Because such exposure may cause adverse health effects, particularly in children, the sources and patterns of exposure need to be studied further. OBJECTIVES:We assessed young urban/suburban children'...

journal_title：Environmental health perspectives

authors： Lu C,Barr DB,Pearson MA,Waller LA

更新日期：2008-04-01 00:00:00

abstract：:Examining global effects of toxic metals on gene expression can be useful for elucidating patterns of biological response, discovering underlying mechanisms of toxicity, and identifying candidate metal-specific genetic markers of exposure and response. Using a 1,200 gene nylon array, we examined changes in gene expres...

journal_title：Environmental health perspectives

authors： Andrew AS,Warren AJ,Barchowsky A,Temple KA,Klei L,Soucy NV,O'Hara KA,Hamilton JW

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Assessing cumulative effects of the multiple environmental factors influencing mortality remains a challenging task. OBJECTIVES:This study aimed to examine the associations between cumulative environmental quality and all-cause and leading cause-specific (heart disease, cancer, and stroke) mortality rates. ...

journal_title：Environmental health perspectives

authors： Jian Y,Messer LC,Jagai JS,Rappazzo KM,Gray CL,Grabich SC,Lobdell DT

更新日期：2017-03-01 00:00:00

abstract：:A wide variety of behavioral methods has been employed with animals to assess visual changes induced by drugs or toxicants. The methods range from simple to complex, from broad screening devices to narrowly focused techniques. Their relative advantages for the environmental toxicologist are discussed. Manipulation of ...

journal_title：Environmental health perspectives

authors： Evans HL

更新日期：1978-10-01 00:00:00

abstract：:To further the development and application of exposure markers in field investigations in reproductive epidemiology, we have synthesized recent examinations of the issues surrounding exposure measurements in reproductive epidemiology. The specific goals of this paper are to define exposure biomarkers and explore their...

journal_title：Environmental health perspectives

authors： Hogue CJ,Brewster MA

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Due to the large number of chemicals not yet tested for carcinogenicity but to which people are exposed, the limited number of human and animal cancer studies conducted each year, and the frequent need for a timely response, mechanistic data are playing an increasingly important role in carcinogen hazard ide...

journal_title：Environmental health perspectives

authors： Atwood ST,Lunn RM,Garner SC,Jahnke GD

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:In a 1994 Ninth Circuit decision on the remand of Daubert v. Merrell Dow Pharmaceuticals, Inc., Judge Alex Kosinski wrote that science done for the purpose of litigation should be subject to more stringent standards of admissibility than other science. OBJECTIVES:We analyze this proposition by considering l...

journal_title：Environmental health perspectives

authors： Boden LI,Ozonoff D

更新日期：2008-01-01 00:00:00

abstract：:We studied peripheral lymphocyte HPRT variant frequency and endogenous nitrosation in human populations exposed to various nitrate levels in their drinking water. Four test populations of women volunteers were compared. Low and medium tap water nitrate exposure groups (14 and 21 subjects) were using public water suppl...

journal_title：Environmental health perspectives

authors： van Maanen JM,Welle IJ,Hageman G,Dallinga JW,Mertens PL,Kleinjans JC

更新日期：1996-05-01 00:00:00

abstract：:Along the Texas-Mexico border, the prevalence of neural tube defects (NTDs) among Mexican-American women doubled during 1990-1991. The human outbreak began during the same crop year as epizootics attributed to exposure to fumonisin, a mycotoxin that often contaminates corn. Because Mexican Americans in Texas consume l...

journal_title：Environmental health perspectives

authors： Missmer SA,Suarez L,Felkner M,Wang E,Merrill AH Jr,Rothman KJ,Hendricks KA

更新日期：2006-02-01 00:00:00

abstract：:The 26th annual conference of the International Society for Environmental Epidemiology was held 24-28 August 2014 in Seattle, Washington. The conference theme was "From Local to Global: Advancing Science for Policy in Environmental Health." Sessions highlighted results assessing the burden of diseases from environment...

journal_title：Environmental health perspectives

authors：

更新日期：2014-10-30 00:00:00

abstract：:The association of malignant mesothelioma (MM) and nonoccupational asbestos exposure is currently debated. Our study investigates environmental and domestic asbestos exposure in the city where the largest Italian asbestos cement (AC) factory was located. This population-based case-control study included pleural MM (hi...

journal_title：Environmental health perspectives

authors： Magnani C,Dalmasso P,Biggeri A,Ivaldi C,Mirabelli D,Terracini B

更新日期：2001-09-01 00:00:00

abstract：:I examined non-Hispanic Black and non-Hispanic White differences in exposure to noncriteria air pollutants in 44 U.S. Census Bureau-defined metropolitan areas with populations greater than one million, using data on air toxics concentrations prepared for the U.S. Environmental Protection Agency as part of its Cumulati...

journal_title：Environmental health perspectives

authors： Lopez R

更新日期：2002-04-01 00:00:00

abstract：:The Children's Post-Pesticide Application Exposure Study (CPPAES) was conducted to look at the distribution of chlorpyrifos within a home environment for 2 weeks after a routine professional crack-and-crevice application and to determine the amount of the chlorpyrifos that is absorbed by a child living within the home...

journal_title：Environmental health perspectives

authors： Hore P,Robson M,Freeman N,Zhang J,Wartenberg D,Ozkaynak H,Tulve N,Sheldon L,Needham L,Barr D,Lioy PJ

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Modern toxicology is shifting from an observational to a mechanistic science. As part of this shift, high-throughput toxicity assays are being developed using alternative, nonmammalian species to prioritize chemicals and develop prediction models of human toxicity. METHODS:The nematode Caenorhabditis elegan...

journal_title：Environmental health perspectives

authors： Boyd WA,Smith MV,Co CA,Pirone JR,Rice JR,Shockley KR,Freedman JH

更新日期：2016-05-01 00:00:00

abstract：:The populations of the developed nations of the world exhibit an increase in blood pressure with age, while in primitive societies blood pressure remains relatively constant throughout adult life. Hypertension may be a complex of diseases all having the same clinical manifestations but not being caused necessarily by ...

journal_title：Environmental health perspectives

authors： Tuthill RW,Calabrese EJ

更新日期：1979-04-01 00:00:00

abstract：:Martineau et al. (2002) reported that St. Lawrence beluga (SLB) have high cancer rates. Unfortunately, errors in their interpretation of the data have led them to overstate the importance of cancer and its links to environmental sources. ...

journal_title：Environmental health perspectives

authors： Hammill MO,Lesage V,Kingsley MC

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Global climate change is anticipated to reduce future cereal yields and threaten food security, thus potentially increasing the risk of undernutrition. The causation of undernutrition is complex, and there is a need to develop models that better quantify the potential impacts of climate change on population ...

journal_title：Environmental health perspectives

authors： Lloyd SJ,Kovats RS,Chalabi Z

更新日期：2011-12-01 00:00:00

abstract：:The spatial and temporal regulation of intracellular free Ca2+ serves as a modulator of signal transduction pathways involved in cell growth and differentiation. Thus, interference of metals with intracellular Ca2+ homeostasis has been considered as a target of toxic action. We used the fluorescence indicator fura-2 t...

journal_title：Environmental health perspectives

authors： Hechtenberg S,Beyersmann D

更新日期：1994-09-01 00:00:00

abstract：:Soil samples were collected from 28 fields which had received manure from Michigan's most highly contaminated dairy herds. The number of fields in each concentration range of PBB in soil were: 2, not detectable; 15, 0.0 to 8.0 ppb; 6, 14-102 ppb, and 5, 153 to 371 ppb. Plant tissue sampled from the 10 most highly cont...

journal_title：Environmental health perspectives

authors： Jacobs LW,Chou SF,Tiedje JM

更新日期：1978-04-01 00:00:00

abstract：OBJECTIVE:We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water. DATA SOURCES AND EXTRACTION:The initial starting point was the background document for the development of the WHO's guideline value for manganese in drinking wat...

journal_title：Environmental health perspectives

authors： Ljung K,Vahter M

更新日期：2007-11-01 00:00:00

abstract：:A review of the present understanding of asthma leads to the following conclusions: an elevated IgE is the principal risk factor in the development of childhood asthma; secondary exposure to a wide range of environmental agents (including indoor bioallergens) accounts for the variations in prevalence; prevalence (defi...

journal_title：Environmental health perspectives

authors： Bates DV

更新日期：1995-09-01 00:00:00

abstract：:A wide range of chemicals with diverse structures derived from plant and environmental origins are reported to have hormonal activity. The potential for appreciable exposure of humans to such substances prompts the need to develop sensitive screening methods to quantitate and evaluate the risk to the public. Yeast cel...

journal_title：Environmental health perspectives

authors： Coldham NG,Dave M,Sivapathasundaram S,McDonnell DP,Connor C,Sauer MJ

更新日期：1997-07-01 00:00:00

abstract：:Striking similarities have been observed in a number of extrapulmonary responses of rodents to seemingly disparate ambient pollutants. These responses are often characterized by primary decreases in important indices of cardiac and thermoregulatory function, along with secondary decreases in associated parameters. For...

journal_title：Environmental health perspectives

authors： Watkinson WP,Campen MJ,Nolan JP,Costa DL

更新日期：2001-08-01 00:00:00