Abstract:
:Structurally diverse dextrans from Leuconostoc mesenteroides and related bacteria have been used extensively in fundamental immunochemical studies such as induction and characterization of anti-dextran antibodies, as well as in studies of their interaction with pneumococcal antisera, normal bovine serum, concanavalin A, dextran-binding myeloma immunoglobulins and hybridoma antibodies. The inherent lack of specificity of structural data obtained by POSA and general lack of insight into other limitations of these analyses has often led to inaccurate and superficial interpretations. Proper interpretation of past and future studies necessitates pointing out previous inadequacies of dextran structural data and detailing more recently acquired structural information on the dextrans. Unambiguous terminology has been achieved by a new system of linkage symbols that includes the designation of structural positions, such as (1----3; l)- and (1----3; b) as linear-chain and branch-point positions, respectively. Results of immunological studies are reviewed. Improved interpretations and correlations are made on the basis of structural data from MSA and several other techniques which have become available on the dextrans.
journal_name
Mol Immunoljournal_title
Molecular immunologyauthors
Jeanes Adoi
10.1016/0161-5890(86)90131-8subject
Has Abstractpub_date
1986-09-01 00:00:00pages
999-1028issue
9eissn
0161-5890issn
1872-9142journal_volume
23pub_type
杂志文章,评审abstract::We designed the peptide (C3) mimetic carboxyl-terminus (Cterminus) of capsid protein of porcine circovirus type 2b (PCV2b-1A/1B) inducing humoral immunity and generating hybridomas. The positive reactivity of the mAbs to PCV2 capsid protein was demonstrated by Western blot assay. Those mAbs also showed positive signal...
journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2017.02.001
更新日期:2017-05-01 00:00:00
abstract::Hyperimmune absorbed rabbit antisera which were reactive with epitopes specific for individual variants of human placental alkaline phosphatase were tested for their reactivity with primate placental alkaline phosphatases. Using the three epitope-specific reactivities defined previously, we found that: epitope I is pr...
journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(84)90074-9
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abstract::TRIMCyp generated by retrotransposition of a cyclophilin A inserting into TRIM5 locus, has been identified in owl monkey and most of Old World monkeys (OWM). Owl monkey TRIMCyp (omTRIMCyp) inhibits HIV-1 infection by direct interaction with viral capsid and indirect innate immune induction, whereas most of TRIMCyps fr...
journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2018.08.001
更新日期:2018-09-01 00:00:00
abstract::The immune system protects from infections primarily by detecting and eliminating invading pathogens. This is predominantly mediated by innate immune cells like neutrophils, monocytes and dendritic cells (DCs) expressing specific receptors recognizing pathogen-associated molecular patterns. DC activation by pathogens ...
journal_title:Molecular immunology
pub_type: 杂志文章,评审
doi:10.1016/j.molimm.2020.02.015
更新日期:2020-05-01 00:00:00
abstract::A variety of important cellular functions are regulated by cytokines. The Jak-STAT pathway is one of the important signaling pathways downstream of cytokine receptors. Following binding of a ligand to its cognate receptor, receptor-associated Jaks are activated. STAT proteins are then in turn activated by tyrosine pho...
journal_title:Molecular immunology
pub_type: 杂志文章,评审
doi:10.1016/s0161-5890(00)00018-3
更新日期:2000-01-01 00:00:00
abstract::Bombyx mori nucleopolyhedrovirus (BmNPV) is one of the main pathogens that seriously affect the sustainable development of sericulture industry. Inhibition of Hsp90 by Hsp90 inhibitor, geldanamycin (GA) significantly suppresses BmNPV proliferation in Bombyx mori, while the functional mechanism is not clear. LncRNA has...
journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2020.09.014
更新日期:2020-11-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/s0161-5890(97)00109-0
更新日期:1997-08-01 00:00:00
abstract::A cDNA clone, designated sbIL-6 (seabream interleukin-6), was obtained from a cDNA library of enriched immune-stimulated sequences from gilthead seabream. The deduced sbIL-6 protein corresponds to a 225-amino acid protein with a putative 24-amino acid signal peptide, four conserved alpha helices and one N-linked glyco...
journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2008.04.012
更新日期:2008-07-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2008.02.020
更新日期:2008-06-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2013.05.004
更新日期:2013-12-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2009.04.023
更新日期:2009-07-01 00:00:00
abstract::Chlorophyllin (CHL) was earlier shown to reduce the level of intracellular ROS and apoptosis induced by ionizing radiation and 2,2'-azobis(2-propionimidinedihydrochloride) (AAPH). In the present studies, the effect of CHL on radiation-induced immunosuppression and modulation of immune responses in mice was examined. C...
journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2006.02.031
更新日期:2007-01-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2005.10.005
更新日期:2006-04-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2012.07.001
更新日期:2013-01-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2016.12.005
更新日期:2017-01-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2016.12.021
更新日期:2017-02-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2016.09.005
更新日期:2016-11-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2016.09.006
更新日期:2016-10-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章,评审
doi:10.1016/j.molimm.2020.02.019
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2017.01.008
更新日期:2017-03-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2008.09.024
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(93)90125-u
更新日期:1993-08-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2017.01.027
更新日期:2017-05-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2010.01.026
更新日期:2010-04-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(85)90007-0
更新日期:1985-10-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(91)90134-6
更新日期:1991-06-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2014.06.028
更新日期:2014-11-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2014.01.015
更新日期:2014-06-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2011.03.018
更新日期:2011-07-01 00:00:00
abstract::In human peripheral blood, most of the CD3+ cells express the alpha/beta T cell receptor. A smaller fraction of CD3+ T cells express the gamma/delta T cell receptor (from 1 to 10% depending the individuals, with an average of 3-5%). Interestingly, although the alpha/beta + T cells never express the gamma chain at the ...
journal_title:Molecular immunology
pub_type: 杂志文章,评审
doi:10.1016/0161-5890(92)90001-e
更新日期:1992-04-01 00:00:00