Comprehensive analysis of lncRNA-mRNA regulatory network in BmNPV infected cells treated with Hsp90 inhibitor.

abstract：:Bifunctional antigens composed of one L-tyrosine-p-azobenzenearsonate (Tyr-ABA) carrier epitope and one dinitrophenyl (DNP) haptenic epitope separated by 6-aminocaproyl or polyprolyl spacers induced weak IgM anti-DNP plaque-forming cell (PFC) responses in the spleens of mice immunized intraperitoneally, without detect...

journal_title：Molecular immunology

authors： Kaymakcalan Z,Nitecki DE,Lewis GK,Goodman JW

更新日期：1984-06-01 00:00:00

abstract：:Jackfruit lectin, jacalin, prepared from two batches of jackfruit seeds showed a different specificity in precipitating reaction in Agarose gel with various purified immunoglobulins and secretory components. Jacalin-P, extracted from jackfruit seeds from the Philippines, reacts only with serum IgA and secretory IgA of...

journal_title：Molecular immunology

authors： Kondoh H,Kobayashi K,Hagiwara K

更新日期：1987-11-01 00:00:00

abstract：:The expression and ligand binding activity of Fc receptors for IgG (Fc gamma R) on guinea-pig peripheral blood polymorphonuclear leukocytes (blood PMN) have been compared with those on casein-elicited peritoneal PMN (exudate PMN). Both the PMN were found to express two distinct types of Fc gamma R, one specific for Ig...

journal_title：Molecular immunology

authors： Fukuchi Y,Sato M,Yamashita T,Koyama J

更新日期：1992-05-01 00:00:00

abstract：:The Class II Transactivator (CIITA) is the master regulator of Major Histocompatibility Class II (MHC II) genes. Transcription of CIITA through the IFN-γ inducible CIITA promoter IV (CIITA pIV) during activation is characterized by a decrease in trimethylation of histone H3 lysine 27 (H3K27me3), catalyzed by the histo...

journal_title：Molecular immunology

authors： Boyd NH,Morgan JE,Greer SF

更新日期：2015-10-01 00:00:00

abstract：:Membrane immunoglobulins are integral proteins on B cell surfaces that bind foreign antigens and are critically involved in the regulation of the immune response. Based upon the model of serum IgG, it has been assumed that membrane immunoglobulins are essentially four chain disulfide-linked structures of the form H2L2...

journal_title：Molecular immunology

authors： Alhasan S,Santini R,Li Q,Rosenspire A

更新日期：1993-12-01 00:00:00

abstract：:A recent report indicated that T200 molecules interact with elements of the cytoskeleton in BW5147 T lymphoma cells. We have confirmed the cytoskeletal association of T200 by examining nonionic detergent-soluble and detergent-insoluble fractions of murine T cell tumor cell lines, cloned cytotoxic T lymphocyte lines, a...

journal_title：Molecular immunology

authors： Taffs RE,Ewald SJ

更新日期：1989-10-01 00:00:00

abstract：:The transcription factor NF-kappaB plays critical roles in immune and inflammatory responses. Here we show that filarial parasitic sheath proteins cause activation of NF-kappaB in the airway epithelial HEp-2 cell line. This activation was transient and saturable, and involved degradation of the cytoplasmic inhibitor p...

journal_title：Molecular immunology

authors： Narayanan K,Balakrishnan A,Miyamoto S

更新日期：2000-02-01 00:00:00

abstract：:p38 mitogen-actived protein kinases (MAPKs) broadly exist from yeast to mammals and participate in diverse cellular responses to various stimuli, whose activation can be induced by the MAPK kinase 6 (MKK6). In this study, a novel MKK6 homolog from Litopenaeus vannamei (LvMKK6) was cloned and characterized. The transcr...

journal_title：Molecular immunology

authors： Li H,Wang S,Qian Z,Wu Z,Lǚ K,Weng S,He J,Li C

更新日期：2016-02-01 00:00:00

abstract：:REV1 plays a key role in vertebrate translesion synthesis. Although its deoxycytidyl transferase activity is dispensable for tolerance of DNA damage caused by a number of mutagens, its extreme C terminus, which interacts with other translesion polymerases and PCNA, is essential. By examining immunoglobulin diversifica...

journal_title：Molecular immunology

authors： Ross AL,Sale JE

更新日期：2006-04-01 00:00:00

abstract：:The xenotransplantation research is driven by the shortage of allografts for transplantation of patients with end-stage organ failure and by lack of success in developing suitable artificial organs. Pigs are now generally accepted to be the donor species of choice, although a possible risk for transmission of xenozoon...

journal_title：Molecular immunology

authors： Mollnes TE,Fiane AE

更新日期：1999-03-01 00:00:00

abstract：:The carbohydrate binding properties of a novel member of the subfamily of galactose-specific jacalin-related lectin isolated from the bark of black mulberry (Morus nigra) (Morniga G) was studied in detail by enzyme-linked lectinosorbent and inhibition assays using panels of monomeric saccharides, mammalian polyvalent ...

journal_title：Molecular immunology

authors： Singh T,Wu JH,Peumans WJ,Rougé P,Van Damme EJ,Wu AM

更新日期：2007-01-01 00:00:00

abstract：:An antimicrobial polypeptide was purified from an acidified gill extract of Pacific oyster (Crassostrea gigas) by C(18) reversed-phase HPLC. The purified polypeptide had a molecular weight of 8471Da containing 74 amino acid residues. Comparison of the obtained N-terminal sequences with those of others revealed that it...

journal_title：Molecular immunology

authors： Seo JK,Lee MJ,Go HJ,Kim GD,Jeong HD,Nam BH,Park NG

更新日期：2013-01-01 00:00:00

abstract：:Staphylococcus aureus is an etiological agent of human and animal diseases, and it is able to internalize into non-professional phagocytic cells (i.e. bovine mammary epithelial cells, bMECs), which is an event that is related to chronic and recurrent infections. bMECs contribute to host innate immune responses (IIR) t...

journal_title：Molecular immunology

authors： Alva-Murillo N,Medina-Estrada I,Báez-Magaña M,Ochoa-Zarzosa A,López-Meza JE

更新日期：2015-12-01 00:00:00

abstract：:The cell-surface receptor ST2L triggers cytokine release by immune cells upon exposure to its ligand IL-33. To study the effect of ST2L-dependent signaling in different cell types, we generated antagonist antibodies that bind different receptor domains. We sought to characterize their activities in vitro using both tr...

journal_title：Molecular immunology

authors： Fursov N,Lu J,Healy C,Wu SJ,Lacy E,Filer A,Li Y,Liu C,Lamb R,Jones B,Reddy R,Petley T,Duffy K

更新日期：2016-07-01 00:00:00

abstract：:The O-antigen of the gram negative bacteria Brucella is composed of an homopolymer of 4,6-dideoxy-4-formamido-alpha-D-mannopyranosyl (or perosamine). Several mAb interact specifically with only the O-antigen of certain Brucella species. Although, many studies show that this specific recognition results mainly from the...

journal_title：Molecular immunology

authors： Laurent TC,Mertens P,Dierick JF,Letesson JJ,Lambert C,De Bolle X

更新日期：2004-03-01 00:00:00

abstract：:Mycobacterium leprae, the causative agent of leprosy, challenges host defense mechanism by impairing the signal transduction of T cells which leads to downregulation of T cell proliferation, mainly as a consequence of interference with IL-2 production. In this study we sought to identify how soluble forms of M. leprae...

journal_title：Molecular immunology

authors： Chattree V,Khanna N,Rao DN

更新日期：2007-03-01 00:00:00

abstract：:Linear IgE-binding epitopes identified in legumin allergens of peanut (Ara h 3) and other allergenic tree nuts (Jug r 4 of walnut, Cor a 9 of hazelnut, Ana o 2 cashew nut) were mapped on three-dimensional models of the proteins built up by homology modelling. A conformational analysis revealed that consensual surface-...

journal_title：Molecular immunology

authors： Barre A,Jacquet G,Sordet C,Culerrier R,Rougé P

更新日期：2007-05-01 00:00:00

abstract：:It is widely believed that migrating immune cells utilise the intercellular junctions as routes of passage, and in doing so cause the transient disruption of junctional structures. Thus there is much interest in the molecules that have been identified at cell-cell contact points and their potential involvement in the ...

journal_title：Molecular immunology

authors： Williams LA,Martin-Padura I,Dejana E,Hogg N,Simmons DL

更新日期：1999-12-01 00:00:00

abstract：:Complement per se has been shown to play an important role in demyelinating disease but controversy remains regarding the role of C3 in the development and progression of experimental autoimmune encephalomyelitis (EAE), the animal model for multiple sclerosis. In this study, we used C3(-/-) mice to confirm previous fi...

journal_title：Molecular immunology

authors： Szalai AJ,Hu X,Adams JE,Barnum SR

更新日期：2007-05-01 00:00:00

abstract：:Most of the complement proteins in circulation are, by and large, synthesized in the liver. However data accumulated over the past several decades provide incontrovertible evidence that some if not most of the individual complement proteins are also synthesized extrahepatically by activated as well as non-activated ce...

journal_title：Molecular immunology

authors： Ghebrehiwet B,Hosszu KH,Peerschke EI

更新日期：2017-04-01 00:00:00

abstract：:In order to improve our knowledge of the human immunoglobulin variable lambda locus (IGLV), we mapped one cosmid clone (designated as C40.2) isolated by screening a Colo320HSR genomic library. The 34 kb insert of the C40.2 clone was shown to contain six genes. One gene, IGLV2S1, belongs to the V lambda II subgroup. Fo...

journal_title：Molecular immunology

authors： Frippiat JP,Lefranc MP

更新日期：1994-06-01 00:00:00

abstract：:Endogenous mouse mammary tumor proviruses (MMTV; Mtv loci) deletes Vbeta6 expressing T cells in the thymus of Mtv-7(+) DBA/2 (H2(d)) mice through negative selection. We found that in Mtv-7(-) BALB/c (H2(d)) mice, Vbeta6 is a dominant V gene used in T cell responses to an 18 amino acid long peptide antigen: EYKEYAEYAEY...

journal_title：Molecular immunology

authors： Kilgannon P,Novak Z,Fotedar A,Singh B

更新日期：2010-02-01 00:00:00

abstract：:Crotoxin (Ctx) is the main lethal component of Crotalus durissus terrificus venom. It is a neurotoxin, composed of two subunits associated by noncovalent interactions, the non-toxic acid subunit (CA), named Crotapotin, and the basic subunit (CB), with phospholipase A2 (PLA2) activity. Employing the SPOT synthesis tech...

journal_title：Molecular immunology

authors： Molina Molina DA,Guerra-Duarte C,Costal-Oliveira F,Almeida Rocha E,Rego Rodrigues C,Machado-de-Ávila RA,Soccol VT,Chávez-Olórtegui C

更新日期：2020-03-01 00:00:00

abstract：:Mannose-binding lectin (MBL) and the ficolins (Ficolin-1, Ficolin-2 and Ficolin-3) are soluble collagen-like proteins that are involved in innate immune defence. They bind sugar structures or acetylated compounds present on microorganisms and on dying host cells and they initiate activation of the lectin complement pa...

journal_title：Molecular immunology

authors： Garred P,Honoré C,Ma YJ,Munthe-Fog L,Hummelshøj T

更新日期：2009-09-01 00:00:00

abstract：:Dendritic cells (DCs) are the professional antigen-presenting cells (APC) which efficiently prime the immune response or induce tolerance. We recently identified Dendritic Cell Specific TrAnsMembrane Protein (DC-STAMP), a novel 470 amino acid protein preferentially expressed by dendritic cells. Previously we demonstra...

journal_title：Molecular immunology

authors： Eleveld-Trancikova D,Sanecka A,van Hout-Kuijer MA,Looman MW,Hendriks IA,Jansen BJ,Adema GJ

更新日期：2010-07-01 00:00:00

abstract：:The site of the murine IgG1 molecule that regulates catabolism has recently been shown to encompass amino acids that are located at the CH2-CH3 domain interface. The CH2 and CH3 domains are connected to each other by a relatively flexible "mini-hinge" region, and flexibility in this region could clearly affect the ori...

journal_title：Molecular immunology

authors： Kim JK,Tsen MF,Ghetie V,Ward ES

更新日期：1995-05-01 00:00:00

abstract：:The pentacyclic triterpene α,β-amyrin has been previously reported as an effective compound in the treatment of several inflammatory conditions. Recent evidence indicates that α,β-amyrin displayed its effects through interaction with the cannabinoid pathway. We assessed the anti-inflammatory effects of the α,β-amyrin ...

journal_title：Molecular immunology

authors： Matos I,Bento AF,Marcon R,Claudino RF,Calixto JB

更新日期：2013-07-01 00:00:00

abstract：:Signal transduction by the B cell receptor (BCR) is an absolute requirement for the selection and development of B lymphocytes at multiple checkpoints. Binding to antigen via the BCR is complemented by a co-stimulus delivered through accessory and co-stimulatory cell surface molecules that regulate the signalling thre...

journal_title：Molecular immunology

authors： Galloway TS,Ray K,Malhotra R

更新日期：2003-01-01 00:00:00

abstract：:It has been developed an HIV type 1 transgenic rat model (HIV-1 Tg Rat) which contains a gag-pol-deleted HIV-1 provirus regulated by the viral LTR promoter. Although it harbors a non infectious provirus, efficient viral expression occurs in different tissues and disease manifestations as well as immune-response altera...

journal_title：Molecular immunology

authors： Mazzucchelli R,Amadio M,Curreli S,Denaro F,Bemis K,Reid W,Bryant J,Riva A,Galli M,Zella D

更新日期：2004-08-01 00:00:00

abstract：:A Brucella abortus protein with a molecular weight of 50 kDa has been shown to bind bovine immunoglobulin G from healthy, brucellosis-free animals. The Brucella immunoglobulin G binding molecule appears to be a protein, since it is susceptible to proteolysis. The protein is presumed to be located on the cell surface, ...

journal_title：Molecular immunology

authors： Bricker BJ,Tabatabai LB,Mayfield JE

更新日期：1991-01-01 00:00:00