Alkali-labile photolesions mapping to purine sites in ultraviolet-irradiated DNA.

abstract：:Targeted mutagenesis and gene knock-out can be mediated by triple helix-forming oligonucleotides (TFO) linked to mutagenic agents, such as psoralen. However, this strategy is limited by the availability of homopurine/homopyrimidine stretches at or near the target site because such sequences are required for high-affin...

journal_title：Photochemistry and photobiology

authors： Raha M,Lacroix L,Glazer PM

更新日期：1998-03-01 00:00:00

abstract：:This study outlines the potential for Computational Fluid Dynamics (CFD) simulation to be used to predict upper-room ultraviolet germicidal irradiation (UVGI) effectiveness to aid system design and the development of future guidance. A numerical study of two wall-mounted UVGI lamps in a mechanically ventilated test ch...

journal_title：Photochemistry and photobiology

authors： Gilkeson CA,Noakes C

更新日期：2013-07-01 00:00:00

abstract：:Ultraviolet radiation (UVR) is hazardous to patients with photosensitive skin disorders, such as lupus erythematosus, xeroderma pigmentosum and skin cancer. As such, these patients are advised to minimize their exposure to UVR. Classically, this is accomplished through careful avoidance of sun exposure and artificial ...

journal_title：Photochemistry and photobiology

authors： Klein RS,Werth VP,Dowdy JC,Sayre RM

更新日期：2009-07-01 00:00:00

abstract：:The distribution of anthocyanins in grape (Vitis vinifera L.) bunches from the Sangiovese cultivar was measured nondestructively by chlorophyll fluorescence imaging using two excitation light bands at 550 and 650 nm in sequence. The pixel intensity in the derived logarithm of the fluorescence excitation ratio image wa...

journal_title：Photochemistry and photobiology

authors： Agati G,Traversi ML,Cerovic ZG

更新日期：2008-11-01 00:00:00

abstract：:Using information on solar irradiance at different latitudes derived from a radiative transfer model and a detailed in vivo action spectrum for immune suppression in a murine system, we report here calculations of the "biologically effective" irradiance of sunlight for immune suppression. From 40 degrees N to 40 degre...

journal_title：Photochemistry and photobiology

authors： De Fabo EC,Noonan FP,Frederick JE

更新日期：1990-10-01 00:00:00

abstract：:The cellular uptake of Photofrin II (PII) was studied using fluorescence imaging and chemical extraction. The influence of serum and low density lipoproteins (LDL) was examined under a variety of experimental conditions employing cultured human cells of different origins as well as a subcutaneously SMT-F tumor implant...

journal_title：Photochemistry and photobiology

authors： Korbelik M,Hung J,Lam S,Palcic B

更新日期：1990-02-01 00:00:00

abstract：:Chlorprothixene (CPTX, Taractan) is a low potency antipsychotic mainly used for the treatment of psychotic disorders (e.g. schizophrenia) and acute mania occurring as part of bipolar disorders. As in the case of other numerous drugs used in the treatment of psychiatric disorders, CPTX presents geometric isomerism. The...

journal_title：Photochemistry and photobiology

authors： Piñero LE,García C,Lhiaubet-Vallet V,Oyola R,Miranda MA

更新日期：2009-07-01 00:00:00

abstract：:Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA...

journal_title：Photochemistry and photobiology

authors： Park CJ,Lee JH,Choi BS

更新日期：2007-01-01 00:00:00

abstract：:The design, synthesis and application of a new fluorescent-labeling reagent for collagen has been developed as a prerequisite for the design of a photoactivated collagen-crosslinking compound for surgical wound closure. The amine groups in collagen are the targets of a rational design for a new fluorophore because nat...

journal_title：Photochemistry and photobiology

authors： Timberlake GT,Reddy GK,Stehno-Bittel L,Weber JF,Amslinger S,Givens RS

更新日期：2002-11-01 00:00:00

abstract：:Pyocyanin (PyO-) (1-hydroxy-5-methylphenazine) is a cytotoxic compound secreted by Pseudomonas aeruginosa, an omnipresent bacterium and a human pathogen. We report that visible light illumination in the presence of rose bengal, or riboflavin, in aerated solutions (pH 7.0-7.2) induces irreversible loss of the pigment's...

journal_title：Photochemistry and photobiology

authors： Reszka KJ,Denning GM,Britigan BE

更新日期：2006-03-01 00:00:00

abstract：:UV-induced toxicity is characterized by marked oxidative stress, accompanied by the depletion of key cellular antioxidants, particularly glutathione (GSH). Replenishing cellular GSH may represent a means of counteracting UV-induced toxicity: however, treatment with free GSH is not therapeutically effective due to its ...

journal_title：Photochemistry and photobiology

authors： Wright D,Zampagni M,Evangelisti E,Conti S,D'Adamio G,Goti A,Becatti M,Fiorillo C,Taddei N,Cecchi C,Liguri G

更新日期：2013-03-01 00:00:00

abstract：:We report the spectroscopic properties of fluorescein, x-rhodamine, tetramethyl-rhodamine, attached to single strand, duplex DNA, and to the digestion products by DNAse I. The properties reported include: molar absorptivity, quantum yield, absorbance and fluorescence spectra, fluorescence lifetime, intrinsic lifetime ...

journal_title：Photochemistry and photobiology

authors： Delgadillo RF,Parkhurst LJ

更新日期：2010-03-01 00:00:00

abstract：:Phototherapy with broadband UVB is an effective treatment for inflammatory dermatoses. A newly developed fluorescent UVB lamp (Philips TL01) that emits a narrowband UVB around 311 nm was shown to be superior for the phototherapy of psoriasis. In order to contribute to the knowledge about the carcinogenic potential of ...

journal_title：Photochemistry and photobiology

authors： Tzung TY,Rünger TM

更新日期：1998-06-01 00:00:00

abstract：:In this study, we aimed to analyze the effects of low-level laser therapy (LLLT; 660 nm) on levels of protein expression of inflammatory mediators after cutting Achilles tendon of rats. Thirty Wistar male rats underwent partial incisions of the left Achilles tendon, and were divided into three groups of 10 animals acc...

journal_title：Photochemistry and photobiology

authors： Laraia EM,Silva IS,Pereira DM,dos Reis FA,Albertini R,de Almeida P,Leal Junior EC,de Tarso Camillo de Carvalho P

更新日期：2012-11-01 00:00:00

abstract：:A major difficulty in photodynamic therapy is the poor solubility of the photosensitizer (PS) under physiological conditions which correlates with low bioavailability. PS aggregation leads to a decrease in the photodynamic efficiency and a more limited activity in vitro and in vivo. To improve the aqueous solubility a...

journal_title：Photochemistry and photobiology

authors： García Vior MC,Marino J,Roguin LP,Sosnik A,Awruch J

更新日期：2013-03-01 00:00:00

abstract：:Many biomolecules contain photoactive reducing agents, such as reduced nicotinamide adenine dinucleotide (NADH) and 6-thioguanine (6-TG) incorporated into DNA through drug metabolism. These reducing agents may produce reactive oxygen species under UVA irradiation or act as electron donors in various media. The interac...

journal_title：Photochemistry and photobiology

authors： Quinones M,Zhang Y,Riascos P,Hwang HM,Aker WG,He X,Gao R

更新日期：2014-03-01 00:00:00

abstract：:Exposure of solutions containing both tryptophan and hydrogen peroxide to a pulsed ( approximately 180 fs) laser beam at 750 nm induces luminescence characteristic of 5-hydroxytryptophan. The results indicate that 3-photon excitation of tryptophan results in photoionization within the focal volume of the laser beam. T...

journal_title：Photochemistry and photobiology

authors： Bisby RH,Crisostomo AG,Botchway SW,Parker AW

更新日期：2009-01-01 00:00:00

abstract：:Phototropin is a blue light-activated photoreceptor that plays a dominant role in the phototropism of plants. The protein contains two subunits that bind flavin mononucleotide (FMN), which are responsible for the initial steps of the light-induced reaction. It has been proposed that the photoexcited flavin molecule ad...

journal_title：Photochemistry and photobiology

authors： Neiss C,Saalfrank P

更新日期：2003-01-01 00:00:00

abstract：:Many viral infections reach clinical significance in winter, when it is cold, relative humidity is lowest and vitamin D production from solar ultraviolet-B irradiation is at its nadir. Several autoimmune diseases, such as multiple sclerosis, type 1 diabetes mellitus and asthma, are linked to viral infections. Vitamin ...

journal_title：Photochemistry and photobiology

authors： Grant WB

更新日期：2008-03-01 00:00:00

abstract：:Three substituted tetraazaporphyrins, octa-(4-tert-butylphenyl)-tetrapyrazinoporphyrazine, tetra-(4-tert-butyl)phthalocyanine and tetra-(4-tert-butyl)phthalocyanatomagnesium(t4-PcMg), were spectroscopically checked in solutions and liposomes with respect to suitability as potential sensitizers of a possible new start ...

journal_title：Photochemistry and photobiology

authors： Teuchner K,Pfarrherr A,Stiel H,Freyer W,Leupold D

更新日期：1993-03-01 00:00:00

abstract：:A novel Cs0.33 WO3 /LDHs (CWLDH) composite was synthesized by simple two steps solvothermal method and first investigated as the photocatalyst for tetracycline (TC) and Congo red (CR) degradation under visible light irradiation. The CWLDH heterostructures catalysts were characterized by XRD, UV-Vis, SEM, XPS and BET. ...

journal_title：Photochemistry and photobiology

authors： Zhang D,Ji T,Yu J,Jiang X,Jiao F

更新日期：2018-03-01 00:00:00

abstract：:Central venous catheters (CVC) are widely used in the United States and are associated with 250,000 to 500,000 CVC-related infections in hospitals annually. We used a catheter made from ultraviolet-C (UVC) transmissive material to test whether delivery of UVC from the lumen would allow inactivation of microorganisms o...

journal_title：Photochemistry and photobiology

authors： Dai T,Tegos GP,St Denis TG,Anderson D,Sinofsky E,Hamblin MR

更新日期：2011-01-01 00:00:00

abstract：:Ultraviolet radiation can inhibit immune responses locally as well as systemically. Such effects have been measured in animals and humans exposed to ultraviolet B (wavelength 280-315 nm) (UVB) and ultraviolet A (315-400 nm) (UVA). The precise wavelength dependence is important for the identification of possible molecu...

journal_title：Photochemistry and photobiology

authors： Garssen J,de Gruijl F,Mol D,de Klerk A,Roholl P,Van Loveren H

更新日期：2001-04-01 00:00:00

abstract：:The pharmacokinetics of Zn phthalocyanine (ZnPc) encapsulated in dipalmitoyl-phosphatidylcholine (DPPC) liposomes, injected intravenously in Skh:HR-1 nude mice, was monitored by two in vitro techniques and one in vivo technique, all based on fluorescence spectroscopy. The in vitro methods involve either fluorescence m...

journal_title：Photochemistry and photobiology

authors： Biolo R,Jori G,Kennedy JC,Nadeau P,Pottier R,Reddi E,Weagle G

更新日期：1991-01-01 00:00:00

abstract：:Low-level light therapy has been used in health care as a therapeutic strategy for different diseases. However, its effects on cancer are controversial. This work evaluated the effects of three energies on breast cancer-bearing mice after a single red light-emitting diode (LED) irradiation. 4T1 cells were inoculated i...

journal_title：Photochemistry and photobiology

authors： Pereira ST,Silva CR,Nuñez SC,Ribeiro MS

更新日期：2020-10-03 00:00:00

abstract：:The recently discovered photo-activated adenylyl cyclase (mPAC from Microcoleus chthonoplastes) is the first PAC that owes a light-, oxygen- and voltage-sensitive (LOV) domain for blue-light sensing. The photoreaction of the mPAC receptor was studied by time-resolved UV/vis and light-induced Fourier transform infrared...

journal_title：Photochemistry and photobiology

authors： Kerruth S,Langner P,Raffelberg S,Gärtner W,Heberle J

更新日期：2017-05-01 00:00:00

abstract：:We have investigated the factors that affect the virucidal activity of methylene blue (MB) photosensitization. The M13 bacteriophage was more rapidly inactivated at higher temperatures (6 degrees C < 24 degrees C < 38 degrees C). Rate constants for inactivation were 0.072, 0.139 and 0.260 (log10 inactivation)/ (J/cm2)...

journal_title：Photochemistry and photobiology

authors： Abe H,Wagner SJ,Kuwabara M,Kamo N,Ikebuchi K,Sekiguchi S

更新日期：1997-05-01 00:00:00

abstract：:The red-shift of furocoumarin action spectra, compared with their absorption spectra, has been investigated. An action spectrum for 8-methoxypsoralen (8-MOP) monoadduct formation in the yeast Candida albicans has been determined. The yeast cells were initially exposed to sublethal doses of monochromatic UVA at differe...

journal_title：Photochemistry and photobiology

authors： Baydoun SA,Gibbs NK,Young AR

更新日期：1989-12-01 00:00:00

abstract：:The retinal protonated Schiff base of bacteriorhodopsin is photoreactive to reducing agents such as NaBH4. In the present work we have studied the effect of different protein hydration levels on the photoreductive reaction, as well as the consequences of preventing isomerization around the critical C13=C14 retinal dou...

journal_title：Photochemistry and photobiology

authors： Aharoni A,Ottolenghi M,Sheves M

更新日期：2002-06-01 00:00:00

abstract：:Under physiological conditions B-form DNA is an exceedingly stable structure. However, experimental evidences obtained through nuclear magnetic resonance and fluorescence anisotropy suggest that the structure of the double helix fluctuates substantially. We describe photoacoustic phase modulation frequency measurement...

journal_title：Photochemistry and photobiology

authors： Bugs MR,Cornélio ML

更新日期：2001-10-01 00:00:00