Abstract:
:In this study, we aimed to analyze the effects of low-level laser therapy (LLLT; 660 nm) on levels of protein expression of inflammatory mediators after cutting Achilles tendon of rats. Thirty Wistar male rats underwent partial incisions of the left Achilles tendon, and were divided into three groups of 10 animals according to the time of euthanasia after injury: 6, 24 and 72 h. Each group was then divided into control group and LLLT group (treated with 100 mW, 3.57 W cm(-2), 0.028 cm(2), 214 J cm(-2), 6 J, 60 s, single point). In LLLT group, animals were treated once time per day until the time of euthanasia established for each group. The group treated with LLLT showed a significant reduction of IL-1β compared with control groups at three time points (6 h: P=0.0401; 24 h: P=0.0015; 72 h: P=0.0463). The analysis of IL-6 showed significant reduction only in the LLLT group at 72 h compared with control group (P=0.0179), whereas IL-10 showed a significant increase in the treated group compared with control group at three experimental times (6 h: P=0.0007; 24 h: P=0.0256; 72 h: P<0.0001). We conclude that LLLT is an important modulator of inflammatory cytokines release after injury in Achilles tendon.
journal_name
Photochem Photobioljournal_title
Photochemistry and photobiologyauthors
Laraia EM,Silva IS,Pereira DM,dos Reis FA,Albertini R,de Almeida P,Leal Junior EC,de Tarso Camillo de Carvalho Pdoi
10.1111/j.1751-1097.2012.01179.xsubject
Has Abstractpub_date
2012-11-01 00:00:00pages
1546-50issue
6eissn
0031-8655issn
1751-1097journal_volume
88pub_type
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