Determination of the distribution of malathion in rats following various routes of administration by whole-body electronic autoradiography.

Abstract:

:The distribution of [14C]-malathion, an organophosphorus pesticide, in rats after intravenous, oral and dermal administration was carried out using electronic autoradiography of whole body sections of treated animals. The study indicated that a major difference in the disposition of [14C]-malathion occurred following various routes of administration to rats. Following intravenous administration, the liver and kidney accumulated extremely high levels of the chemical. After oral administration, [14C]-malathion absorption from the stomach was slow and its excretion followed mostly the fecal route. Dermal application of [14C]-malathion may represent a high risk for exposure to the organophosphorus pesticide where the entire skin, not only the site of application, may act as reservoir for the compound.

journal_name

Toxicol Ind Health

authors

Saleh MA,Ahmed AE,Kamel A,Dary C

doi

10.1177/074823379701300605

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

751-8

issue

6

eissn

0748-2337

issn

1477-0393

journal_volume

13

pub_type

杂志文章
  • Injury and infection in dental clinics: Risk factors and prevention.

    abstract::Needlestick and sharp instrument injuries are common in dental practice and present the risk of direct exposure to blood-borne pathogens, including hepatitis B virus. This cross-sectional study was carried out to determine the risk factors of injury and infection in three types of dental clinic in Riyadh, Saudi Arabia...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233718769553

    authors: Al-Zoughool M,Al-Shehri Z

    更新日期:2018-09-01 00:00:00

  • Method validation for aflatoxin M1 determination in yoghurt using immunoaffinity column clean-up prior to high-performance liquid chromatography.

    abstract::Yoghurt is a popular dairy product in Iran because of its beneficial influence on human health and nutritional value. Aflatoxin M1 (AFM1) is the metabolite of potential carcinogen aflatoxin B1, which can contaminate milk through the feed and is not eliminated by common processing heat treatment. An analytical method u...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233710394236

    authors: Tabari M,Karim G,Ghavami M,Chamani M

    更新日期:2011-08-01 00:00:00

  • Physiological and biochemical mechanisms of allelopathy mediated by the allelochemical extracts of Phytolacca latbenia (Moq.) H. Walter.

    abstract::In allelopathy, one plant suppresses the growth and development of other plant/plants by negatively affecting a variety of physiological and biochemical reactions. We checked the effects of methanolic extracts (allelochemical extracts) of Phytolacca latbenia (Moq.) H. Walter on antioxidant enzyme activities such as pe...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233713483205

    authors: Ullah N,Haq IU,Safdar N,Mirza B

    更新日期:2015-10-01 00:00:00

  • Occupational manganese exposure, reproductive hormones, and semen quality in male workers: A cross-sectional study.

    abstract::It has been found that exposure to manganese (Mn) could induce reproductive dysfunction, but its occupational risk in male workers is unclear. This study aims to assess the association of occupational Mn exposure with reproductive hormones and semen quality in a cross-sectional study. Urinary Mn, semen quality, and re...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233718810109

    authors: Yang H,Wang J,Yang X,Wu F,Qi Z,Xu B,Liu W,Deng Y

    更新日期:2019-01-01 00:00:00

  • Prevention of mobile phone induced skin tissue changes by melatonin in rat: an experimental study.

    abstract::Most of the mobile phones in Turkey emit 900 MHz radiation which is mainly absorbed by the skin and, to a lesser extent, muscle. The aim of this study was to investigate the effects the 900 MHz electromagnetic irradiation emitted by these devices on the induction of histopathologic changes in skin and the effect of me...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1191/0748233704th207oa

    authors: Ozguner F,Aydin G,Mollaoglu H,Gökalp O,Koyu A,Cesur G

    更新日期:2004-09-01 00:00:00

  • Effects of washing, peeling, storage, and fermentation on residue contents of carbaryl and mancozeb in cucumbers grown in greenhouses.

    abstract::Cucumbers grown in two different greenhouses were exposed to mancozeb and carbaryl at different times. The effects of 10-day preharvest period, water and detergent washing, peeling, predetermined storage period at 4°C (refrigeration), and fermentation on the reduction of residue levels in the plant tissues were invest...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233714552295

    authors: Saeedi Saravi SS,Shokrzadeh M

    更新日期:2016-06-01 00:00:00

  • Comparative study of zinc oxide nanoparticles and its bulk form on liver function of Wistar rat.

    abstract::Zinc oxide nanoparticles (ZnO NPs) are produced in high tonnage each year; they are widely used in consumer and industrial products, also now finding applications in bioimaging and drug delivery. In the present study, comparison between ZnO NPs (39 nm) and its bulk/micron form (particle size = 5 µm) on liver function ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233719878970

    authors: Moatamed ER,Hussein AA,El-Desoky MM,Khayat ZE

    更新日期:2019-10-01 00:00:00

  • Assessment of exposure to cadmium, lead, manganese, and nickel in workers from foundries.

    abstract:OBJECTIVES:In this study, biological exposure indicators were used to assess the exposure of workers to cadmium (Cd), lead (Pb), manganese (Mn), and nickel (Ni) in nonferrous metal smelters. METHODS:A total of 273 male participants (178 exposed and 95 nonexposed control group), working in nonferrous metal foundries lo...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233715589262

    authors: Dos Santos CR,da Silva CS,Nascimento ES

    更新日期:2016-10-01 00:00:00

  • Detection of macrocyclic trichothecene mycotoxin in a caprine (goat) tracheal instillation model.

    abstract::This study demonstrates the detection and dynamics of macrocyclic trichothecene mycotoxin (MTM) tissue loading using a commercially available assay in a goat model. The detection of MTMs has been difficult and complex due to the uncertainty of what tissues to examine and when to sample. Twelve goats (two groups of eac...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233709348275

    authors: Layton RC,Purdy CW,Jumper CA,Straus DC

    更新日期:2009-10-01 00:00:00

  • Pesticide sorption on geologic material of varying organic carbon content.

    abstract::Sorption of three pesticides on geologic material ranging in organic carbon content from 0.33 to 6.9 g kg-1 was measured in soil columns using a miscible displacement technique. An octanol-water partitioning model was shown to be inappropriate for predicting sorption of the less hydrophobic pesticides on the low organ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823378800400306

    authors: Bouchard DC,Wood AL

    更新日期:1988-09-01 00:00:00

  • Screening of microbial contamination and antimicrobial activity of sea cucumber Holothuria polii.

    abstract::Microbiological studies were carried out on microbial contamination and antimicrobial activity of sea cucumber Holothuria polii collected from Mediterranean Sea at Abu-kir shore of Alexandria, Egypt. The obtained results revealed the presence of isolates of five human Gram-negative pathogenic bacteria, representing fi...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233712448116

    authors: Omran NE,Allam NG

    更新日期:2013-11-01 00:00:00

  • Health effects from hazardous waste incineration facilities: five case studies.

    abstract::Environmental pollution, primarily from industrialization, has caused significant adverse effects to humans, animals, and the ecosystem. Attempts have been made to reduce and prevent these pollutants through better waste management practices. Incineration is one such practice, which seeks to prevent adverse health imp...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章,评审

    doi:

    authors: Pleus RC,Kelly KE

    更新日期:1996-03-01 00:00:00

  • Recent progress in the eye irritation test.

    abstract::The rabbit eye irritation test based on the Draize method is required for the hazard assessment of chemicals and products that may come into contact with the eye. Due to the potential for the suffering of animals and subjectivity of the test, many modifications of the method have been made that involved a reduction in...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章,评审

    doi:10.1177/074823379300900602

    authors: Chu IH,Toft P

    更新日期:1993-11-01 00:00:00

  • Effect of paraoxonase 1 192 Q/R polymorphism on paraoxonase and acetylcholinesterase enzyme activities in a Turkish population exposed to organophosphate.

    abstract::Organophosphate (OP) compounds are the most commonly used pesticide groups and they are commercially used in the market for local and industrial purposes. Paraoxonase 1 (PON1) enzyme plays an important role in biotransformation of OP compounds, which shows toxic effects via inhibiting the acetylcholinesterase (AChE). ...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233713487246

    authors: Sunay SZ,Kayaaltı Z,Bayrak T,Söylemezoğlu T

    更新日期:2015-12-01 00:00:00

  • Effect of nanosilver on blood parameters in chickens having aflatoxicosis.

    abstract::This experiment is designed to investigate the positive effects of commercial nanosilver compound on blood parameters in experimental aflatoxicosis in broiler chickens. For this, 270 one-day-old broiler chickens were randomly divided into six treatment groups with three replicates. The experimental groups were group A...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233712452611

    authors: Gholami-Ahangaran M,Zia-Jahromi N

    更新日期:2014-03-01 00:00:00

  • Prediction of lung cancer risk using circulating pro-surfactant protein B and high-sensitivity C-reactive protein among Egyptian workers in the rubber industry.

    abstract:OBJECTIVE:For several decades, there has been increasing evidence for excess incidence of lung cancer among workers in the rubber industry. The purpose of this study was to assess the risk of lung cancer occurrence among Egyptian workers involved in the rubber industry using two circulating protein biomarkers. METHODS...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233720923504

    authors: Mourad BH

    更新日期:2020-04-01 00:00:00

  • Lys- and Leu-aminopeptidase activity after acute toluene exposure in the rat brain.

    abstract::Changes in Lys- and Leu-aminopeptidase activities in several brain regions of the rat, after acute toluene administration, are described in this research. Aminopeptidase activity has been suggested as a candidate regulator of the degradation of several neuroactive peptides. Lys-aminopeptidase activity was significantl...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823379300900310

    authors: De Gandarias JM,Echevarria E,Irazusta J,Casis E,Casis L

    更新日期:1993-05-01 00:00:00

  • Psychological bases of symptom reporting: perceptual and emotional aspects of chemical sensitivity.

    abstract::The reporting of physical symptoms is influenced to a large degree by psychological processes. Individuals are more likely to notice subtle sensations in environments lacking in stimulation than those demanding external attention. The beliefs or schemas that people hold dictate where and how they attend to their bodie...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章,评审

    doi:

    authors: Pennebaker JW

    更新日期:1994-07-01 00:00:00

  • Hypolipidemic effect of fruit fibers in rats fed with high dietary fat.

    abstract::The hypolipidemic effect of 10% fruit fibers in rats fed with high-fat diet (HFD) was evaluated. This study was conducted on a total of 50 male Albino rats divided into 10 equal groups fed with different types of dietary fruits. The feeding period lasted for 24 weeks. Fasting blood samples were collected and sera sepa...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233712472526

    authors: Esmael OA,Sonbul SN,Kumosani TA,Moselhy SS

    更新日期:2015-03-01 00:00:00

  • Thrombocytosis induced in mice after subacute and subchronic V2O5 inhalation.

    abstract::Reports about vanadium (V) inhalation toxicity on the hematopoietic system, specifically about coagulation are limited. Therefore, we decided to evaluate the effects of V with a complete blood count and morphologic analysis of platelets on blood smears. CD-1 male mice inhaled V2O5 0.02 M 1 h twice weekly over 12 weeks...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1191/0748233706th250oa

    authors: González-Villalva A,Fortoul TI,Avila-Costa MR,Piñón-Zarate G,Rodriguez-Laraa V,Martínez-Levy G,Rojas-Lemus M,Bizarro-Nevarez P,Díaz-Bech P,Mussali-Galante P,Colin-Barenque L

    更新日期:2006-04-01 00:00:00

  • The accumulation of pyrophosphate by rat hepatocytes.

    abstract::Hepatocytes that were isolated from 48 hr starved rats and incubated in Krebs-Henseleit bicarbonate buffer containing 10 microM A23187, 10mM l-lactate, 1mM pyruvate and 2mM l-lysine were found to contain 0.064 mumol of inorganic pyrophosphate/g wet wgt cells. Addition of either 20mM acetate or butyrate, which caused t...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823378600200308

    authors: Gitomer WL,Veech RL

    更新日期:1986-09-01 00:00:00

  • Inhalation toxicity study of methanol, toluene, and methanol/toluene mixtures in rats: effects of 28-day exposure.

    abstract::The inhalation toxicity of methanol and toluene was investigated in rats. Young Sprague Dawley rats of both sexes were exposed to vapors of methanol (300 ppm, 3000 ppm), toluene (30 ppm, 300 ppm) or methanol/toluene (300/30 ppm, 300/300 ppm, 3000/30 ppm, and 3000/300 ppm) six hrs per day, five days/week for four weeks...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823379401000310

    authors: Poon R,Chu I,Bjarnason S,Potvin M,Vincent R,Miller RB,Valli VE

    更新日期:1994-05-01 00:00:00

  • Cancer incidence among male military and civil pilots and flight attendants: an analysis on published data.

    abstract::Flight personnel are exposed to cosmic ionizing radiation, chemicals (fuel, jet engine exhausts, cabin air pollutants), electromagnetic fields from cockpit instruments, and disrupted sleep patterns. Only recently has cancer risk among these workers been investigated. With the aim of increasing the precision of risk es...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章,meta分析

    doi:10.1191/0748233705th238oa

    authors: Buja A,Lange JH,Perissinotto E,Rausa G,Grigoletto F,Canova C,Mastrangelo G

    更新日期:2005-11-01 00:00:00

  • Low concentrations of copper in drinking water increase AP-1 binding in the brain.

    abstract::Copper (Cu) in trace amounts is essential for biological organisms. However, dysregulation of the redox-active metal has been implicated in different neurological disorders such as Wilson's, Menkes', Alzheimer's, and Parkinson's diseases. Since many households use Cu tubing in the plumbing system, and corrosion causes...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233713491805

    authors: Lung S,Li H,Bondy SC,Campbell A

    更新日期:2015-12-01 00:00:00

  • Subchronic toxicity studies indicate that tris(2-chloroethyl)phosphate administration results in lesions in the rat hippocampus.

    abstract::Tris(2-chloroethyl)phosphate (TRCP), a flame-retardant plasticizer used in plastics, polymeric foams and synthetic fibers, was studied as part of the National Toxicology Program's class study of phosphate flame-retardants. TRCP was administered at 0, 22, 44, 88, 175 and 350 mg/kg to both sexes of rats and 0, 44, 88, 1...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/074823379000600101

    authors: Matthews HB,Dixon D,Herr DW,Tilson H

    更新日期:1990-01-01 00:00:00

  • Asthma from hair straightening treatment containing formaldehyde: Two cases and a review of the literature.

    abstract::We report two cases of formaldehyde-containing hair straighteners causing new onset asthma. Formaldehyde has been reported to cause asthma in other settings. The purpose of this article is to examine two cases of asthma in hairdressers exposed to hair smoothing products and to review the relevant literature on formald...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233717750982

    authors: Dahlgren JG,Talbott PJ

    更新日期:2018-04-01 00:00:00

  • Extrapulmonary effects of temporal exposure to cigarette smoke.

    abstract::This study aimed to evaluate the extrapulmonary effects of exposure to cigarette smoke (CS) through the analysis of blood components and histopathological examinations of the trachea and diaphragm muscle (DM) in C57BL/6 mice. Thirty-six animals were exposed to six cigarettes per day for 5 days. The mice were divided i...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233717715187

    authors: Martins TL,Campos KKD,Araújo NPDS,Machado DF,Bezerra FS

    更新日期:2017-09-01 00:00:00

  • Fluoride and endosulfan together potentiate cytogenetic effects in Swiss albino mice bone marrow cells.

    abstract::In this study, the cytotoxic potential of fluoride and endosulfan in combination was investigated in Swiss albino mice bone marrow cells using the chromosomal aberration (CA) and micronucleus (MN) test systems. Fluoride (25.1 mg kg-1 body weight [bw] in water) and endosulfan (1.8 mg kg-1 bw by oral intubation) were ad...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233720979423

    authors: Sharma A,John P,Bhatnagar P

    更新日期:2020-12-16 00:00:00

  • Bioantioxidants: the systems reliability standpoint.

    abstract::The antioxidant power of the so-called antioxidants is negligible because their rate constants and concentrations are too small to compete with the specialized defense enzymes, like superoxide dismutase (SOD), for the reactive oxygen species. In this short review, we present a number of experimental data of our group,...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章,评审

    doi:10.1177/0748233709103029

    authors: Koltover VK

    更新日期:2009-05-01 00:00:00

  • Beneficial influence of topical extra virgin olive oil application on an experimental model of penile fracture in rats.

    abstract::Penile fracture (PF) is known as a traumatic rupture of the tunica albuginea of corpus cavernosum. In this study, we aimed to investigate the healing influence of topical extra virgin olive oil (EVOO) on PF through evaluating levels of some oxidative stress biomarkers for the first time. Histopathological evaluation w...

    journal_title:Toxicology and industrial health

    pub_type: 杂志文章

    doi:10.1177/0748233713483191

    authors: Gunes M,Ozkol H,Pirincci N,Gecit I,Bilici S,Yildirim S

    更新日期:2015-08-01 00:00:00