The Microcirculation Physiome Project.

abstract：:Viscous shear stress and Reynolds stress are often used to predict hemolysis and thrombosis due to flow-induced stress on blood elements in cardiovascular devices. These macroscopic stresses are distinct from the true stress on an individual cell, which is determined by the local microscale flow field. In this paper t...

journal_title：Annals of biomedical engineering

authors： Quinlan NJ,Dooley PN

更新日期：2007-08-01 00:00:00

abstract：:Classically, the primary tool for quantifying the dynamics of vergence and other eye movements has been the main sequence. The main sequence is a plot of peak velocity versus response amplitude and is particularly useful for comparing the dynamics of a large number of eye movements over a range of response amplitudes....

journal_title：Annals of biomedical engineering

authors： Alvarez TL,Semmlow JL,Yuan W,Munoz P

更新日期：1999-05-01 00:00:00

abstract：:We have developed poly(L: -lactide-co-glycolide) (PLGA) based composites using sol-gel derived bioactive glasses (S-BG), previously described by our group, as composite components. Two different composite types were manufactured that contained either S2-high content silica S-BG, or A2-high content lime S-BG. The compo...

journal_title：Annals of biomedical engineering

authors： Pamula E,Kokoszka J,Cholewa-Kowalska K,Laczka M,Kantor L,Niedzwiedzki L,Reilly GC,Filipowska J,Madej W,Kolodziejczyk M,Tylko G,Osyczka AM

更新日期：2011-08-01 00:00:00

abstract：:Radiation applied for therapy and diagnostics damages molecular/atomic couples of biotissues, bones being among them. As a result, electron peculiarities and mechanical behavior of the latter are altered. Correlation between strength of the irradiated bone and its electron features explored due to photo- and exoelectr...

journal_title：Annals of biomedical engineering

authors： Dekhtyar Y

更新日期：2001-12-01 00:00:00

abstract：:In this study, we have developed an integrated microfluidic platform for actively patterning mammalian cells, where poly(ethylene glycol) (PEG) hydrogels play two important roles as a non-fouling layer and a dielectric structure. The developed system has an embedded array of PEG microwells fabricated on a planar indiu...

journal_title：Annals of biomedical engineering

authors： Tsutsui H,Yu E,Marquina S,Valamehr B,Wong I,Wu H,Ho CM

更新日期：2010-12-01 00:00:00

abstract：:This paper reviews the applications of accelerometers on the detection of physiological acoustic signals such as heart sounds, respiratory sounds, and gastrointestinal sounds. These acoustic signals contain a rich reservoir of vital physiological and pathological information. Accelerometer-based systems enable continu...

journal_title：Annals of biomedical engineering

authors： Hu Y,Kim EG,Cao G,Liu S,Xu Y

更新日期：2014-11-01 00:00:00

abstract：:Twenty-one 3.5-month-old female Sprague-Dawley rats were randomly assigned to three groups: BTX group, in which each rat received a single intramuscular injection of 2 U of Clostridium botulinum toxin (BTX) in the quadriceps femoris muscle of the right hind limb; BTX + SR group, in which each rat received a BTX inject...

journal_title：Annals of biomedical engineering

authors： Sheng ZF,Ma YL,Tong D,Fang DY,Liang QC,Liu LH,Zhang J,Liao EY

更新日期：2012-03-01 00:00:00

abstract：:The local dilation of the infrarenal abdominal aorta, termed an abdominal aortic aneurysm (AAA), is often times asymptomatic and may eventually result in rupture-an event associated with a significant mortality rate. The estimation of in-vivo stresses within AAAs has been proposed as a useful tool to predict the likel...

journal_title：Annals of biomedical engineering

authors： Vande Geest JP,Schmidt DE,Sacks MS,Vorp DA

更新日期：2008-06-01 00:00:00

abstract：:Changes in fetal magnetocardiographic (fMCG) signals are indicators for fetal body movement. We propose a novel approach to reliably extract fetal body movements based on the field strength of the fMCG signal independent of its frequency. After attenuating the maternal MCG, we use a Hilbert transform approach to ident...

journal_title：Annals of biomedical engineering

authors： Govindan RB,Vairavan S,Ulusar UD,Wilson JD,McKelvey SS,Preissl H,Eswaran H

更新日期：2011-03-01 00:00:00

abstract：:Past literature has provided evidence that a normal mechanical force environment of blood flow may guide normal development while an abnormal environment can lead to congenital malformations, thus warranting further studies on embryonic cardiovascular flow dynamics. In the current study, we developed a non-invasive 4D...

journal_title：Annals of biomedical engineering

authors： Ho S,Tan GXY,Foo TJ,Phan-Thien N,Yap CH

更新日期：2017-10-01 00:00:00

abstract：:The bioinspired, microscale tissue engineering approach has emerged in recent years as a promising alternative to preformed scaffolds. Using this approach, complex tissues and organs can be efficiently engineered from microscale modules to replicate the intricate architecture and physiology of vascularized organs and ...

journal_title：Annals of biomedical engineering

authors： Annamalai RT,Matthew HWT

更新日期：2019-05-01 00:00:00

abstract：:In this study, cell-material adhesive strength and cellular mechanical properties were measured using atomic force microscopy (AFM) to track cell attachment and osteogenic differentiation. First, chitosan substrates were treated with simulated body fluid (SBF) for various periods, resulting in substrates with differen...

journal_title：Annals of biomedical engineering

authors： Ho MH,Li CH,Hsiao SW,Thien DV

更新日期：2015-04-01 00:00:00

abstract：:Hemodynamic parameters play an important role in regulating vascular remodeling in arterio-venous fistula (AVF) maturation. Investigating the changes in hemodynamic parameters during AVF maturation is expected to improve our understanding of fistula failure, but very little data on actual temporal changes in human AVF...

journal_title：Annals of biomedical engineering

authors： Sigovan M,Rayz V,Gasper W,Alley HF,Owens CD,Saloner D

更新日期：2013-04-01 00:00:00

abstract：:In an ovine femur model, proliferative woven bone fills critically sized defects enveloped by periosteum within 2 weeks of treatment with the one-stage bone-transport surgery. We hypothesize that mechanical loading modulates this process. Using high-definition optical strain measurements we determined prevailing perio...

journal_title：Annals of biomedical engineering

authors： McBride SH,Dolejs S,Brianza S,Knothe U,Knothe Tate ML

更新日期：2011-05-01 00:00:00

abstract：:A modified conductance method to determine the cross-sectional areas (CSAs) of arteries in piglets was evaluated in vivo. The method utilized a conductance catheter having four electrodes. Between the outer electrodes an alternating current was applied and between the inner electrodes the induced voltage difference wa...

journal_title：Annals of biomedical engineering

authors： Kornet L,Jansen JR,Gussenhoven EJ,Hardeman MR,Hoeks AP,Versprille A

更新日期：1999-03-01 00:00:00

abstract：:The geometric and hemodynamic characteristics of the left and right vertebral arteries (LVA, RVA) of six healthy volunteers were investigated for the supine (S) and the prone position (P) a common sleeping posture with head rotation. MRI images were used to reconstruct the subject specific three-dimensional solid mode...

journal_title：Annals of biomedical engineering

authors： Aristokleous N,Seimenis I,Georgiou GC,Nicolaides A,Anayiotos AS

更新日期：2015-06-01 00:00:00

abstract：:Rod photoreceptors express a unique type of noninactivating potassium channels, Kx channels, which play an important role in setting the dark potential and participate in shaping the light response. Biophysical studies of Kx channels are limited. For example, the effects of a conventional blocker of potassium channels...

journal_title：Annals of biomedical engineering

authors： Liu XD,Kourennyi DE

更新日期：2004-10-01 00:00:00

abstract：:Parameters of physiological models are commonly associated in an input-output experiment with a specific pattern of the system response. This association is often made on an intuitive basis by traditional sensitivity analysis, i.e., by inspecting the variations of model output trajectories with respect to parameter va...

journal_title：Annals of biomedical engineering

authors： Thomaseth K,Cobelli C

更新日期：1999-09-01 00:00:00

abstract：:A number of human head finite element (FE) models have been developed from different research groups over the years to study the mechanisms of traumatic brain injury. These models can vary substantially in model features and parameters, making it important to evaluate whether simulation results from one model are read...

journal_title：Annals of biomedical engineering

authors： Ji S,Ghadyani H,Bolander RP,Beckwith JG,Ford JC,McAllister TW,Flashman LA,Paulsen KD,Ernstrom K,Jain S,Raman R,Zhang L,Greenwald RM

更新日期：2014-01-01 00:00:00

abstract：:Optimal treatment of proximal humerus fractures remains controversial. Locking plates offer theoretical advantages but are associated with complications in the clinic. This study aimed to perform parametric design optimisation of proximal humerus plates to enhance their mechanical performance. A finite element (FE) mo...

journal_title：Annals of biomedical engineering

authors： Jabran A,Peach C,Zou Z,Ren L

更新日期：2019-02-01 00:00:00

abstract：:Collagen is known to be a viscoelastic material and therefore is an important source of time dependent behavior in soft tissue. Though there are material models for soft tissue that rely on properties and structure of constituent collagen fibers, such models generally utilize only the elastic properties of collagen, a...

journal_title：Annals of biomedical engineering

authors： Bischoff JE

更新日期：2006-07-01 00:00:00

abstract：:Accurate identification of contracting muscles can help us to understand the muscle function in both physiological and pathological conditions. Conventional electromyography (EMG) have limited access to deep muscles, crosstalk, or instability in the recordings. Accordingly, a novel framework was developed to detect co...

journal_title：Annals of biomedical engineering

authors： Zheng Y,Shin H,Kamper DG,Hu X

更新日期：2021-01-01 00:00:00

abstract：:Continuous measurement of arterial blood density after bolus injection of fluids of different density into the right atrium has been used to measure cardiac output and mean transit time through the central circulation. The transit time distribution for density, however, differs from that for plasma-phase tracers such ...

journal_title：Annals of biomedical engineering

authors： Ligas JR,Moslehi F,Epstein MA

更新日期：1993-07-01 00:00:00

abstract：:Image registration and motion estimation play central roles in many fields, including RADAR, SONAR, light microscopy, and medical imaging. Because of its central significance, estimator accuracy, precision, and computational cost are of critical importance. We have previously presented a highly accurate, spline-based ...

journal_title：Annals of biomedical engineering

authors： Viola F,Coe RL,Owen K,Guenther DA,Walker WF

更新日期：2008-12-01 00:00:00

abstract：:Currently, autologous cartilage provides the gold standard for auricular reconstruction. However, synthetic biomaterials offer a number of advantages for ear reconstruction including decreased donor site morbidity and earlier surgery. Critical to implant success is the material's mechanical properties as this affects ...

journal_title：Annals of biomedical engineering

authors： Griffin MF,Premakumar Y,Seifalian AM,Szarko M,Butler PE

更新日期：2016-12-01 00:00:00

abstract：:In this paper, a new method for quantification of rigidity in elbow joint of Parkinsonian patients is introduced. One of the most known syndromes in Parkinson's disease (PD) is increased passive stiffness in muscles, which leads to rigidity in joints. Clinical evaluation of stiffness in wrist and/or elbow, commonly us...

journal_title：Annals of biomedical engineering

authors： Sepehri B,Esteki A,Ebrahimi-Takamjani E,Shahidi GA,Khamseh F,Moinodin M

更新日期：2007-12-01 00:00:00

abstract：:Neuromuscular impairment associated with cerebral palsy (CP) often leads to life-long walking deficits. Our goal was to evaluate the ability of a novel untethered wearable ankle exoskeleton to reduce the severity of gait pathology from CP. In this clinical feasibility study of five individuals with CP, we used instrum...

journal_title：Annals of biomedical engineering

authors： Lerner ZF,Harvey TA,Lawson JL

更新日期：2019-06-01 00:00:00

abstract：:This work presents a method to unequivocally detect urine sample tampering in cases where integrity of the sample needs to be verified prior to urinalysis. The technique involves the detection of distinct patterns of a triplex short tandem repeats system in DNA extracted from human urine. The analysis is realized with...

journal_title：Annals of biomedical engineering

authors： Pires NMM,Dong T,Yang Z,Santos SMB

更新日期：2020-02-01 00:00:00

abstract：:Alzheimer's disease (AD) is an irreversible brain disorder which represents the most common form of dementia in western countries. An early and accurate diagnosis of AD would enable to develop new strategies for managing the disease; however, nowadays there is no single test that can accurately predict the development...

journal_title：Annals of biomedical engineering

authors： Alonso JF,Poza J,Mañanas MA,Romero S,Fernández A,Hornero R

更新日期：2011-01-01 00:00:00

abstract：:Numerical models of the mitral valve have been used to elucidate mitral valve function and mechanics. These models have evolved from simple two-dimensional approximations to complex three-dimensional fully coupled fluid structure interaction models. However, to date these models lack direct one-to-one experimental val...

journal_title：Annals of biomedical engineering

authors： Rabbah JP,Saikrishnan N,Yoganathan AP

更新日期：2013-02-01 00:00:00