MEG connectivity analysis in patients with Alzheimer's disease using cross mutual information and spectral coherence.

abstract：:Effects of hyperthermia on transport of low-density lipoprotein (LDL) through a stenosed arterial wall are analyzed comprehensively in the present work. The realistic and pertinent aspects of an arterial wall is represented by a multi-layer model, with a proper representation of the thickened intima region due to the ...

journal_title：Annals of biomedical engineering

authors： Iasiello M,Vafai K,Andreozzi A,Bianco N,Tavakkoli F

更新日期：2015-07-01 00:00:00

abstract：:We propose a novel method to reconstruct the hypothetical geometry of the healthy vasculature prior to intracranial aneurysm (IA) formation: a Frenet frame is calculated along the skeletonization of the arterial geometry; upstream and downstream boundaries of the aneurysmal segment are expressed in terms of the local ...

journal_title：Annals of biomedical engineering

authors： Chen H,Selimovic A,Thompson H,Chiarini A,Penrose J,Ventikos Y,Watton PN

更新日期：2013-07-01 00:00:00

abstract：:A search for robust noninvasive methods permitting to discern the respiration subtle peculiarities in mammals is a topical issue. A novel approach called "sorption-enhanced infrared thermography" (SEIRT), helping to solve this problem, is described. Its benefits spring from the integration of the infrared thermography...

journal_title：Annals of biomedical engineering

authors： Vainer BG

更新日期：2018-07-01 00:00:00

abstract：:Step-off edges and tissue interfaces are prevalent in cartilage injury such as after intra-articular fracture and reduction, and in focal defects and surgical repair procedures such as osteochondral graft implantation. It would be useful to assess the function of injured or donor tissues near such step-off edges and t...

journal_title：Annals of biomedical engineering

authors： Bae WC,Law AW,Amiel D,Sah RL

更新日期：2004-03-01 00:00:00

abstract：:Although diagnostic testing with auditory evoked potentials (EPs) has become routine, quantitative measurements of signal and noise are still lacking. In this study, current signal, power, noise power, and signal-to-noise ratio (SNR) estimation formulas are reviewed and applied to auditory brainstem response averaging...

journal_title：Annals of biomedical engineering

authors： Ozdamar O,Delgado RE

更新日期：1996-11-01 00:00:00

abstract：:Biochemical stimulation was applied in combination with cyclic mechanical strain to engineered vascular constructs made of isolated smooth muscle cells in a three-dimensional (3D) collagen type 1 matrix. Platelet-derived growth factor (PDGF) and transforming growth factor beta (TGF-beta) were added exogenously to the ...

journal_title：Annals of biomedical engineering

authors： Stegemann JP,Nerem RM

更新日期：2003-04-01 00:00:00

abstract：:The linear homeomorphic muscle model proposed by Enderle and coworkers for the rectus eye muscle is fitted to reflect the dynamics of muscles in the head-neck complex, specifically in muscles involved in gaze shifts. This parameterization of the model for different muscles in the neck region will serve to drive a 3D d...

journal_title：Annals of biomedical engineering

authors： Sierra DA,Enderle JD

更新日期：2010-02-01 00:00:00

abstract：:Vascular smooth muscle mechanics have been studied in vitro in cylindrical segments of dog carotid artery, human internal mammary artery, and human saphenous vein. Such cylindrical preparations maintain normal vessel geometry and also permit correlation of mechanical phenomena with transmural pressure. These studies s...

journal_title：Annals of biomedical engineering

authors： Dobrin PB

更新日期：1984-01-01 00:00:00

abstract：:To better understand oxygen utilization by the retina, a mathematical model of oxygen diffusion and consumption in the cat outer, avascular retina was developed by analyzing previously recorded profiles of oxygen tension (PO2) as a function of retinal depth. Simple diffusion modelling of the oxygen distribution throug...

journal_title：Annals of biomedical engineering

authors： Haugh LM,Linsenmeier RA,Goldstick TK

更新日期：1990-01-01 00:00:00

abstract：:Uncomplicated acute type B aortic dissections are usually treated medically, but they can become acutely complicated by rapid expansion, rupture and malperfusion syndromes and in the longer term by chronic dilatation and aortic aneurysm formation. The objective of this study is to use computational fluid dynamics reco...

journal_title：Annals of biomedical engineering

authors： Cheng Z,Wood NB,Gibbs RG,Xu XY

更新日期：2015-01-01 00:00:00

abstract：:Despite the use of helmets in American football, brain injuries are still prevalent. To reduce the burden of these injuries, novel impact mitigation systems are needed. The Vicis Zero1 (VZ1) American football helmet is unique in its use of multi-directional buckling structures sandwiched between a deformable outer she...

journal_title：Annals of biomedical engineering

authors： Giudice JS,Caudillo A,Mukherjee S,Kong K,Park G,Kent R,Panzer MB

更新日期：2020-05-01 00:00:00

abstract：:Computing the numerical solution of the bidomain equations is widely accepted to be a significant computational challenge. In this study we extend a previously published semi-implicit numerical scheme with good stability properties that has been used to solve the bidomain equations (Whiteley, J.P. IEEE Trans. Biomed. ...

journal_title：Annals of biomedical engineering

authors： Whiteley JP

更新日期：2008-08-01 00:00:00

abstract：:Blood flow simulations are making their way into the clinic, and much attention is given to estimation of fractional flow reserve in coronary arteries. Intracardiac blood flow simulations also show promising results, and here the flow field is expected to depend on the pulmonary venous (PV) flow rates. In the absence ...

journal_title：Annals of biomedical engineering

authors： Lantz J,Gupta V,Henriksson L,Karlsson M,Persson A,Carlhäll CJ,Ebbers T

更新日期：2019-02-01 00:00:00

abstract：:An intelligent multichannel stimulator (IMS) has been designed and built for use in a cardiac research environment. The device is capable of measuring and responding to cardiac electrophysiological phenomena in real time with carefully timed and placed electrical stimuli. The system consists of 16 channels of sense/st...

journal_title：Annals of biomedical engineering

authors： Johnson PL,Newton JC,Rollins DL,Knisley SB,Ideker RE,Smith WM

更新日期：2002-02-01 00:00:00

abstract：:Continuous measurement of arterial blood density after bolus injection of fluids of different density into the right atrium has been used to measure cardiac output and mean transit time through the central circulation. The transit time distribution for density, however, differs from that for plasma-phase tracers such ...

journal_title：Annals of biomedical engineering

authors： Ligas JR,Moslehi F,Epstein MA

更新日期：1993-07-01 00:00:00

abstract：:Coronary artery bypass graft (CABG) failure has been linked to graft hemodynamics, in particular wall shear stress. This study characterizes the morphology, geometry and wall shear stress patterns in human CABGs. The intimal thickness (IT) in 49 human saphenous vein CABGs was measured by digital light microscopy. The ...

journal_title：Annals of biomedical engineering

authors： Leask RL,Butany J,Johnston KW,Ethier CR,Ojha M

更新日期：2005-03-01 00:00:00

abstract：:The extent to which sensorineural systems such as the auditory system are nonlinear depends on the type of stimulus that is used, and the part of the system from which recordings are made. An estimate of the first-order Wiener kernel of the evoked response from the inferior colliculus to amplitude-modulated tones and ...

journal_title：Annals of biomedical engineering

authors： Møller AR,Angelo RM

更新日期：1988-01-01 00:00:00

abstract：:Recent evidence suggests that energy substrate metabolism forms the link between gene expression and contractile function of the heart. This hypothesis draws on three seemingly unconnected observations, made in 1941 by three different investigators. The first gave rise to the concept of the dynamic nature of body cons...

journal_title：Annals of biomedical engineering

authors： Taegtmeyer H

更新日期：2000-08-01 00:00:00

abstract：:We describe a system for real-time control of biological and other experiments. This device, based around the Real-Time Linux operating system, was tested specifically in the context of dynamic clamping, a demanding real-time task in which a computational system mimics the effects of nonlinear membrane conductances in...

journal_title：Annals of biomedical engineering

authors： Dorval AD,Christini DJ,White JA

更新日期：2001-10-01 00:00:00

abstract：:Cell migration is a fundamental process that is crucial to a variety of physiological events. While traditional approaches have focused on two-dimensional (2D) systems, recent efforts have shifted to studying migration in three-dimensional (3D) matrices. A major distinction that has emerged is the increased importance...

journal_title：Annals of biomedical engineering

authors： Harjanto D,Zaman MH

更新日期：2010-05-01 00:00:00

abstract：:A goal of the Human Research Program at National Aeronautics and Space Administration (NASA) is to analyze and mitigate the risk of occupant injury due to dynamic loads. Experimental tests of human subjects and biofidelic anthropomorphic test devices provide valuable kinematic and kinetic data related to injury risk e...

journal_title：Annals of biomedical engineering

authors： Gaewsky JP,Jones DA,Ye X,Koya B,McNamara KP,Gayzik FS,Weaver AA,Putnam JB,Somers JT,Stitzel JD

更新日期：2019-02-01 00:00:00

abstract：:Recent advances in fluorescence confocal endomicroscopy have allowed real-time identification of residual tumour cells on the walls of the cavity left by breast conserving surgery. However, it is difficult to systematically survey the surgical site because of the small imaging field-of-view of these probes, compounded...

journal_title：Annals of biomedical engineering

authors： Zuo S,Hughes M,Yang GZ

更新日期：2016-07-01 00:00:00

abstract：:Acute cerebral ischemic events and thrombosis are associated with the rupture/erosion of carotid atherosclerotic plaques. The aim of the present study was to determine the impact of calcification deposition on the wall shear stress (WSS) and stresses within the plaques using 3D fluid-structure interaction (FSI) models...

journal_title：Annals of biomedical engineering

authors： Benitez J,Fontanarosa D,Wang J,Paritala PK,McGahan T,Lloyd T,Li Z

更新日期：2020-10-20 00:00:00

abstract：:Arterial tissue is commonly assumed to be incompressible. While this assumption is convenient for both experimentalists and theorists, the compressibility of arterial tissue has not been rigorously investigated. In the current study we present an experimental-computational methodology to determine the compressibility ...

journal_title：Annals of biomedical engineering

authors： Nolan DR,McGarry JP

更新日期：2016-04-01 00:00:00

abstract：:As a human grows from birth to adulthood, both airway anatomy and breathing conditions vary, altering the deposition rate and pattern of inhaled aerosols. However, deposition studies have typically focused on adult subjects, results of which may not be readily extrapolated to children. This study numerically evaluated...

journal_title：Annals of biomedical engineering

authors： Xi J,Berlinski A,Zhou Y,Greenberg B,Ou X

更新日期：2012-12-01 00:00:00

abstract：:For treatment of complex congenital heart disease, computer simulation using a three-dimensional heart model may help to improve outcomes by enabling detailed preoperative evaluations. However, no highly integrated model that accurately reproduces a patient's pathophysiology, which is required for this simulation has ...

journal_title：Annals of biomedical engineering

authors： Kariya T,Washio T,Okada JI,Nakagawa M,Watanabe M,Kadooka Y,Sano S,Nagai R,Sugiura S,Hisada T

更新日期：2020-06-01 00:00:00

abstract：:The toxic or therapeutic effect of an inhaled aerosol is highly dependent upon the site and extent of deposition in the lung. A novel MRI-based method was used to quantify the spatial distribution of particles in the rat lung. Rats were exposed to 0.95 μm-diameter iron oxide particles in a controlled manner (N = 6) or...

journal_title：Annals of biomedical engineering

authors： Oakes JM,Scadeng M,Breen EC,Prisk GK,Darquenne C

更新日期：2013-05-01 00:00:00

abstract：:A limitation of current tissue engineering vascular graft technology is the provision of an expandable, autologous cell source. By harnessing the multipotency of mesenchymal stem cells (MSC), it is hoped that functional vascular cells can be produced. To date, a range of 2D and 3D environments have been investigated f...

journal_title：Annals of biomedical engineering

authors： O'Cearbhaill ED,Murphy M,Barry F,McHugh PE,Barron V

更新日期：2010-03-01 00:00:00

abstract：:Percutaneous stent implantation has revolutionized the clinical treatment of occluded arteries. Nevertheless, there is still a large unmet need to prevent re-occlusion after implantation. Consequently, a niche exists for a cost-effective pre-clinical method of evaluating novel interventional devices in human models. T...

journal_title：Annals of biomedical engineering

authors： Punchard MA,O'Cearbhaill ED,Mackle JN,McHugh PE,Smith TJ,Stenson-Cox C,Barron V

更新日期：2009-07-01 00:00:00

abstract：:In this study, cell-material adhesive strength and cellular mechanical properties were measured using atomic force microscopy (AFM) to track cell attachment and osteogenic differentiation. First, chitosan substrates were treated with simulated body fluid (SBF) for various periods, resulting in substrates with differen...

journal_title：Annals of biomedical engineering

authors： Ho MH,Li CH,Hsiao SW,Thien DV

更新日期：2015-04-01 00:00:00