Measurement of signal and noise characteristics in ongoing auditory brainstem response averaging.

abstract：:A kinetic model based on first principles, for β(2)-microglobulin, is presented to obtain precise parameter estimates for individual patient. To reduce the model complexity, the number of model parameters was reduced using a priori identifiability analysis. The model validity was confirmed with the clinical data of te...

journal_title：Annals of biomedical engineering

authors： Maheshwari V,Samavedham L,Rangaiah GP

更新日期：2011-12-01 00:00:00

abstract：:The identification of the insulin minimal model (MM) for the estimation of insulin secretion rate (ISR) and physiological indexes (e.g. beta-cell sensitivity) requires the knowledge of C-peptide (CP) kinetics. The four parameters of the two-compartment model of CP kinetics in a given individual can be derived either f...

journal_title：Annals of biomedical engineering

authors： Magni P,Sparacino G,Bellazzi R,Toffolo GM,Cobelli C

更新日期：2004-07-01 00:00:00

abstract：:Changes in fetal magnetocardiographic (fMCG) signals are indicators for fetal body movement. We propose a novel approach to reliably extract fetal body movements based on the field strength of the fMCG signal independent of its frequency. After attenuating the maternal MCG, we use a Hilbert transform approach to ident...

journal_title：Annals of biomedical engineering

authors： Govindan RB,Vairavan S,Ulusar UD,Wilson JD,McKelvey SS,Preissl H,Eswaran H

更新日期：2011-03-01 00:00:00

abstract：:Dendritic cell (DC) migration is required for efficient presentation of antigen to T cells and the initiation of an adaptive immune response. In spite of its importance, many aspects of DC migration have not been characterized. DCs encounter a variety of environments with different stiffness and geometry, but the effe...

journal_title：Annals of biomedical engineering

authors： Bendell AC,Anderson N,Blumenthal D,Williamson EK,Chen CS,Burkhardt JK,Hammer DA

更新日期：2018-09-01 00:00:00

abstract：:Conventional nanoporous hydrogels often lead to slow cartilage deposition by MSCs in 3D due to physical constraints and requirement for degradation. Our group has recently reported macroporous gelatin microribbon (μRB) hydrogels, which substantially accelerate MSC-based cartilage formation in vitro compared to convent...

journal_title：Annals of biomedical engineering

authors： Barati D,Gegg C,Yang F

更新日期：2020-07-01 00:00:00

abstract：:Membrane introduction mass spectrometry has been applied to inert gas measurements in blood and tissue, but gases with low blood solubility are associated with reduced sensitivity. Countercurrent extraction of inert gases from a blood sample into a water carrier phase has the potential to extract most of the gas sampl...

journal_title：Annals of biomedical engineering

authors： Baumgardner JE,Neufeld GR

更新日期：1997-09-01 00:00:00

abstract：:Mechanical cues arising from extracellular matrices greatly affect cellular properties, and hence, are of significance in designing biomaterials. In this study, a DNA crosslinked hydrogel was employed to examine cellular responses of spinal cord neurons to substrate compliances. Using DNA as crosslinkers in polymeric ...

journal_title：Annals of biomedical engineering

authors： Jiang FX,Yurke B,Firestein BL,Langrana NA

更新日期：2008-09-01 00:00:00

abstract：:A wide range of length and time scales are relevant to pharmacology, especially in drug development, drug design and drug delivery. Therefore, multiscale computational modeling and simulation methods and paradigms that advance the linkage of phenomena occurring at these multiple scales have become increasingly importa...

journal_title：Annals of biomedical engineering

authors： Clancy CE,An G,Cannon WR,Liu Y,May EE,Ortoleva P,Popel AS,Sluka JP,Su J,Vicini P,Zhou X,Eckmann DM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:We present a fundamental theoretical framework for analysis of energy dissipation in any component of the circulatory system and formulate the full energy budget for both venous and arterial circulations. New indices allowing disease-specific subject-to-subject comparisons and disease-to-disease hemodynamic ...

journal_title：Annals of biomedical engineering

authors： Dasi LP,Pekkan K,de Zelicourt D,Sundareswaran KS,Krishnankutty R,Delnido PJ,Yoganathan AP

更新日期：2009-04-01 00:00:00

abstract：:The nose is the front line defender of the respiratory system. Unsteady simulations in three-dimensional models have been developed to study transport patterns in the human nose and its overall air-conditioning capacity. The results suggested that the healthy nose can efficiently provide about 90% of the heat and the ...

journal_title：Annals of biomedical engineering

authors： Naftali S,Rosenfeld M,Wolf M,Elad D

更新日期：2005-04-01 00:00:00

abstract：:In this study, we introduce the fast wavelet transform as a method for characterizing maturational changes in electrocortical activity, respiratory activity, and blood pressure in fetal lambs in early (110-122 days), mid (123-135 days), and late (136-144 days) third trimester (term 145 days). Each recording was 2 hr i...

journal_title：Annals of biomedical engineering

authors： Akay M,Szeto HH

更新日期：1995-09-01 00:00:00

abstract：:Registration of bone structures is a common problem in medical research as well as in clinical applications. Intrasubject rigid 3D monomodality registration of segmented bone structures of CT images and multimodality registration of muMR and segmented muCT bone images were performed with the multiresolution intensity-...

journal_title：Annals of biomedical engineering

authors： Museyko O,Eisa F,Hess A,Schett G,Kalender WA,Engelke K

更新日期：2010-07-01 00:00:00

abstract：:The development of prevention strategies is critical to address the rising prevalence of sport-related concussions. Visual and sensory performance may influence an individual's ability to interpret environmental cues, anticipate opponents' actions, and create appropriate motor responses limiting the severity of an imp...

journal_title：Annals of biomedical engineering

authors： Harpham JA,Mihalik JP,Littleton AC,Frank BS,Guskiewicz KM

更新日期：2014-01-01 00:00:00

abstract：:We have studied the dependence of conduction velocity (theta) on extracellular potassium concentration ([K+]o) in a model of one-dimensional conduction using an idealized strand of human atrial cells. Elevated [K+]o in the 5-20 mM range shifts the resting potential (Vrest) in the depolarizing direction and reduces inp...

journal_title：Annals of biomedical engineering

authors： Nygren A,Giles WR

更新日期：2000-08-01 00:00:00

abstract：:Arterial responses to diverse pathologies and insults likely occur via similar mechanisms. For example, many studies suggest that the natural process of aging and isolated systolic hypertension share many characteristics in arteries, including loss of functional elastin, decreased smooth muscle tone, and altered rates...

journal_title：Annals of biomedical engineering

authors： Valentín A,Humphrey JD,Holzapfel GA

更新日期：2011-07-01 00:00:00

abstract：:We developed muscle-tendon models incorporating Hill-type structure and length-dependent coupling between activation and velocity. The models were evaluated in electrically stimulated cat soleus muscles. Dynamic model parameters were estimated by a nonlinear parameter estimation algorithm from input-output data obtain...

journal_title：Annals of biomedical engineering

authors： Shue GH,Crago PE

更新日期：1998-05-01 00:00:00

abstract：:A novel electrocardiogram (ECG) electrode film is developed by mixing carbon black powder and a quaternary salt with a visco-elastic polymeric adhesive. Unlike traditional wet gel-based electrodes, carbon/salt/adhesive (CSA) electrodes should theoretically have an infinite shelf life as they do not dehydrate even afte...

journal_title：Annals of biomedical engineering

authors： Posada-Quintero HF,Reyes BA,Burnham K,Pennace J,Chon KH

更新日期：2015-10-01 00:00:00

abstract：:The nonlinear dynamic properties of action potential encoding were studied in mechanosensory neurons innervating the slits of a slit-sense organ in the tropical wandering spider, Cupiennius salei. The organ contains two types of neurons that are morphologically similar but have different dynamic properties. Type A neu...

journal_title：Annals of biomedical engineering

authors： French AS,Sekizawa SI,Höger U,Torkkeli PH

更新日期：2001-03-01 00:00:00

abstract：:Normalized maximal ventricular power (nPWRmax) is an index of cardiac function which measures the innate blood pumping ability, or contractility, of the left ventricle (LV), and its noninvasive assessment could prove useful in a variety of patients. nPWRmax is defined as the maximum instantaneous product of LV pressur...

journal_title：Annals of biomedical engineering

authors： Setser RM,Sayre K,Flacke S,Chia J,Lunn K,Lorenz CH

更新日期：2001-11-01 00:00:00

abstract：:To study pulsatile pressure-flow rate relationships in the intact pulmonary vascular network of mice, we developed a protocol for measuring pulmonary vascular resistance and impedance in isolated, ventilated, and perfused mouse lungs. We used pulmonary emboli to validate the effect of vascular obstruction on resistanc...

journal_title：Annals of biomedical engineering

authors： Tuchscherer HA,Webster EB,Chesler NC

更新日期：2006-04-01 00:00:00

abstract：:Dendritic cells (DCs) are crucial components of the immune response, strategically positioned as immune sentinels. Complex trafficking and accurate positioning of DCs are indispensable for both immunity and tolerance. This is particularly evident for their therapeutic application where an unmet clinical need exists fo...

journal_title：Annals of biomedical engineering

authors： Silva Z,Konstantopoulos K,Videira PA

更新日期：2012-04-01 00:00:00

abstract：:We present here the first quantitative correlation for cell contact guidance in an oriented fibrillar network in terms of biased cell migration. The correlation is between the anisotropic cell diffusion parameter, DA = Dx/Dy, and the collagen gel birefringence, delta n, a measure of axially biased collagen fibril orie...

journal_title：Annals of biomedical engineering

authors： Dickinson RB,Guido S,Tranquillo RT

更新日期：1994-07-01 00:00:00

abstract：:We propose a multiphysical mathematical model by fully coupling lipid deposition, monocytes/macrophages recruitment and angiogenesis to investigate the pathophysiological responses of an atherosclerotic plaque to the dynamic changes in the microenvironment. The time evolutions of cellular (endothelial cells, macrophag...

journal_title：Annals of biomedical engineering

authors： Guo M,Cai Y,He C,Li Z

更新日期：2019-02-01 00:00:00

abstract：:Analysis and classification of esophageal motility records were investigated using signal processing and fuzzy-set pattern recognition techniques. A set of parameters has been extracted from the raw records and has previously been used as characterizing features. Improvements to these procedures were obtained by extra...

journal_title：Annals of biomedical engineering

authors： Abou-Chadi FE,Ezzat FA,Sif el-Din AA

更新日期：1994-01-01 00:00:00

abstract：:Adherence of a biological graft to the wound surface is the most important factor influencing the ultimate success of graft viability. A machine has been developed to test the adherence of biological graft materials to a substrate such as a wound surface. The peeling mode, which yields reproducible quantitative measur...

journal_title：Annals of biomedical engineering

authors： Dong C,Mead E,Skalak R,Fung YC,Debes JC,Zapata-Sirvent RL,Andree C,Greenleaf G,Cooper M,Hansbrough JF

更新日期：1993-01-01 00:00:00

abstract：:Millions of people worldwide are diagnosed each year with valvular heart disease, resulting in hundreds of thousands of valve replacement operations. Prosthetic valve replacements are designed to correct narrowing or backflow through the valvular orifice. Although commonly used, these therapies have serious disadvanta...

journal_title：Annals of biomedical engineering

authors： Berry JL,Steen JA,Koudy Williams J,Jordan JE,Atala A,Yoo JJ

更新日期：2010-11-01 00:00:00

abstract：:Asymmetric 75% and 95% area reduction, transparent Sylgard stenotic models were operated under internal carotid artery (ICA) [Womersley parameter, alpha=5.36, Re(mean) =213 and 180, respectively, and Re(peak)=734 and 410, respectively] and left anterior descending coronary artery (LAD) flow wave forms (alpha=2.65, Re(...

journal_title：Annals of biomedical engineering

authors： Cao J,Rittgers SE

更新日期：1998-03-01 00:00:00

abstract：:An MR image-based computational model of a murine KHT sarcoma is presented that allows the calculation of plasma fluid and solute transport within tissue. Such image-based models of solid tumors may be used to optimize patient-specific therapies. This model incorporates heterogeneous vasculature and tissue porosity to...

journal_title：Annals of biomedical engineering

authors： Pishko GL,Astary GW,Mareci TH,Sarntinoranont M

更新日期：2011-09-01 00:00:00

abstract：:A modified conductance method to determine the cross-sectional areas (CSAs) of arteries in piglets was evaluated in vivo. The method utilized a conductance catheter having four electrodes. Between the outer electrodes an alternating current was applied and between the inner electrodes the induced voltage difference wa...

journal_title：Annals of biomedical engineering

authors： Kornet L,Jansen JR,Gussenhoven EJ,Hardeman MR,Hoeks AP,Versprille A

更新日期：1999-03-01 00:00:00

abstract：:Blood flow simulations are making their way into the clinic, and much attention is given to estimation of fractional flow reserve in coronary arteries. Intracardiac blood flow simulations also show promising results, and here the flow field is expected to depend on the pulmonary venous (PV) flow rates. In the absence ...

journal_title：Annals of biomedical engineering

authors： Lantz J,Gupta V,Henriksson L,Karlsson M,Persson A,Carlhäll CJ,Ebbers T

更新日期：2019-02-01 00:00:00