Mathematical simulation of slowing of cardiac conduction velocity by elevated extracellular.

abstract：:Integration of repair tissue is a key indicator of the long-term success of cell-based therapies for cartilage repair. The objective of this study was to compare the in vitro chondrogenic differentiation and integration of agarose hydrogels seeded with either chondrocytes or bone marrow-derived mesenchymal stem cells ...

journal_title：Annals of biomedical engineering

authors： Vinardell T,Thorpe SD,Buckley CT,Kelly DJ

更新日期：2009-12-01 00:00:00

abstract：:The contractile power of the latissimus dorsi muscle (LDM) is used in skeletal muscle cardiac assist (SMCA) to augment the blood pumping ability of a failing heart. The LDM has three anatomically distinct, independently innervate segments-the transverse, oblique, and lateral. There are potential advantages to selectiv...

journal_title：Annals of biomedical engineering

authors： Thompson DR,Michele JJ,Cheever EA,George DT

更新日期：1999-01-01 00:00:00

abstract：:In this paper, an intelligent proportional-integral-derivative (PID) control method is introduced to the robotic testing system for the biomechanical study of human musculoskeletal joints. For the testing system, the robot is a highly nonlinear and heavily coupled complicated system, and the human spinal specimen also...

journal_title：Annals of biomedical engineering

authors： Tian L

更新日期：2004-06-01 00:00:00

abstract：:Recent studies have demonstrated the ability of magnetic resonance imaging (MRI) to provide anatomically realistic boundary conditions for computational fluid dynamics (CFD) simulations of arterial hemodynamics. To date, however, little is known about the overall reproducibility of such image-based CFD techniques. Tow...

journal_title：Annals of biomedical engineering

authors： Thomas JB,Milner JS,Rutt BK,Steinman DA

更新日期：2003-02-01 00:00:00

abstract：:Optimal treatment of proximal humerus fractures remains controversial. Locking plates offer theoretical advantages but are associated with complications in the clinic. This study aimed to perform parametric design optimisation of proximal humerus plates to enhance their mechanical performance. A finite element (FE) mo...

journal_title：Annals of biomedical engineering

authors： Jabran A,Peach C,Zou Z,Ren L

更新日期：2019-02-01 00:00:00

abstract：:We describe the development of experimental platforms to quantify the regeneration of injured central nervous system (CNS) neurons by combining engineering technologies and primary neuronal cultures. Although the regeneration of CNS neurons is an important area of research, there are no currently available methods to ...

journal_title：Annals of biomedical engineering

authors： Kim HJ,Park JW,Byun JH,Vahidi B,Rhee SW,Jeon NL

更新日期：2012-06-01 00:00:00

abstract：:Linear autoregressive (AR) model-based heart rate (HR) spectral analysis has been widely used to study HR dynamics. Owing to system and measurement noise, the parameters of an AR model have intrinsic statistical uncertainty. In this study, we evaluate how this AR parameter uncertainty can translate to uncertainty in H...

journal_title：Annals of biomedical engineering

authors： Christini DJ,Kulkarni A,Rao S,Stutman ER,Bennett FM,Hausdorff JM,Oriol N,Lutchen KR

更新日期：1995-03-01 00:00:00

abstract：:Polycrystalline silicon (poly-Si) micromechanical structures can be made by selectively etching an underlying sacrificial oxide layer. Advantages of this micromachining technique are its simplicity and compatibility with conventional integrated-circuit processing. Compressive internal stress in poly-Si films constrain...

journal_title：Annals of biomedical engineering

authors： Howe RT

更新日期：1986-01-01 00:00:00

abstract：:Concussion tolerance and head impact exposure are highly variable among football players. Recent findings highlight that head impact data analyses need to be performed at the subject level. In this paper, we describe a method of characterizing concussion risk between individuals using a new survival analysis technique...

journal_title：Annals of biomedical engineering

authors： Rowson S,Campolettano ET,Duma SM,Stemper B,Shah A,Harezlak J,Riggen L,Mihalik JP,Brooks A,Cameron KL,Svoboda SJ,Houston MN,McAllister T,Broglio S,McCrea M

更新日期：2020-11-01 00:00:00

abstract：:Magnetic nanoparticle (mNP) based thermal therapies have demonstrated relevance in the clinic, but effective application requires an understanding of both its strengths and limitations. This study explores two critical limitations for clinical use: (1) maximizing localized mNP heating, while avoiding bulk heating due ...

journal_title：Annals of biomedical engineering

authors： Etheridge ML,Bischof JC

更新日期：2013-01-01 00:00:00

abstract：:The advantages of photoacoustic (PA) imaging, including low cost, non-ionizing operation, and sub-mm spatial resolution at centimeters depth, make it a promising modality to probe nanoparticle-targeted abnormalities in real time at cellular and molecular levels. However, detecting rare cell types in a heterogeneous ba...

journal_title：Annals of biomedical engineering

authors： O'Donnell M,Wei CW,Xia J,Pelivanov I,Jia C,Huang SW,Hu X,Gao X

更新日期：2013-11-01 00:00:00

abstract：:Due to its unique non-invasive microstructure probing capabilities, diffusion tensor imaging (DTI) constitutes a valuable tool in the study of fiber orientation in skeletal muscles. By implementing a DTI sequence with judiciously chosen directional encoding to quantify in vivo the microarchitectural properties in the ...

journal_title：Annals of biomedical engineering

authors： Karampinos DC,King KF,Sutton BP,Georgiadis JG

更新日期：2009-12-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is caused by extensive pulmonary vascular remodeling that increases right ventricular (RV) afterload and leads to RV failure. PAH predominantly affects women; paradoxically, female PAH patients have better outcomes than men. The roles of estrogen in PAH remain controversial, which...

journal_title：Annals of biomedical engineering

authors： Liu A,Hacker T,Eickhoff JC,Chesler NC

更新日期：2017-03-01 00:00:00

abstract：:A method of investigating head acceleration and intracranial dynamics from stick impacts in girls' and women's lacrosse was developed using headform impact experiments and a finite element head model. Assessing the likelihood of head injury due to stick-head impacts is of interest in girls' and women's lacrosse due to...

journal_title：Annals of biomedical engineering

authors： Morse JD,Franck JA,Wilcox BJ,Crisco JJ,Franck C

更新日期：2014-12-01 00:00:00

abstract：:We propose a novel method to reconstruct the hypothetical geometry of the healthy vasculature prior to intracranial aneurysm (IA) formation: a Frenet frame is calculated along the skeletonization of the arterial geometry; upstream and downstream boundaries of the aneurysmal segment are expressed in terms of the local ...

journal_title：Annals of biomedical engineering

authors： Chen H,Selimovic A,Thompson H,Chiarini A,Penrose J,Ventikos Y,Watton PN

更新日期：2013-07-01 00:00:00

abstract：:Phospholipids have been identified by thin-layer chromatography in appreciable quantities in pericardial fluid taken from 12 dogs and found to include sphingomyelin and phosphatidylcholines, -ethanolamines, -inositols and -serines--the cholines predominating. The extracts, the synthetic surfactants and a mixture of sy...

journal_title：Annals of biomedical engineering

authors： Hills BA,Butler BD

更新日期：1985-01-01 00:00:00

abstract：:Most non-invasive blood pressure measurements are based on either the auscultatory or the oscillometric technique. In this study, we performed an extensive analysis of the signals, i.e., responses of a microphone implanted in the cuff and pressure changes in the cuff, which can be recorded during such measurements. We...

journal_title：Annals of biomedical engineering

authors： Jazbinsek V,Luznik J,Mieke S,Trontelj Z

更新日期：2010-03-01 00:00:00

abstract：:Basic fibroblast growth factor (FGF-2) is a potent angiogenic growth factor involved in the development of diseases such as cancer, atherosclerosis, and heart and limb ischemia, as well as normal wound healing and tissue development. Despite being one of the most heavily studied angiogenic growth factors, the binding ...

journal_title：Annals of biomedical engineering

authors： Filion RJ,Popel AS

更新日期：2004-05-01 00:00:00

abstract：:High-frequency ventilation (HFV) has not one but several histories. Proceeding along largely independent pathways are techniques using frequencies of 1-5 Hz and techniques using 10-40 Hz, the former being introduced by Sjostrand in 1971, the latter by Lunkenheimer in 1972. It was nearly ten years before it was recogni...

journal_title：Annals of biomedical engineering

authors： Bryan AC

更新日期：1984-01-01 00:00:00

abstract：:Numerical models of the mitral valve have been used to elucidate mitral valve function and mechanics. These models have evolved from simple two-dimensional approximations to complex three-dimensional fully coupled fluid structure interaction models. However, to date these models lack direct one-to-one experimental val...

journal_title：Annals of biomedical engineering

authors： Rabbah JP,Saikrishnan N,Yoganathan AP

更新日期：2013-02-01 00:00:00

abstract：:During the fetal-to-neonatal transition, transvalvular pressures (TVPs) on the aortic and pulmonary valves change dramatically-but differently for each valve. We have examined changes in the molecular stability and crosslinking of collagen during this transition. Aortic and pulmonary valves were harvested from fetal a...

journal_title：Annals of biomedical engineering

authors： Aldous IG,Lee JM,Wells SM

更新日期：2010-09-01 00:00:00

abstract：:We attempted to estimate in living adherent epithelial alveolar cells, the degree of structural and mechanical heterogeneity by considering two individualized cytoskeleton components, i.e., a submembranous "cortical" cytoskeleton and a "deep" cytoskeleton (CSK). F-actin structure characterizing each CSK component was ...

journal_title：Annals of biomedical engineering

authors： Laurent VM,Fodil R,Cañadas P,Féréol S,Louis B,Planus E,Isabey D

更新日期：2003-11-01 00:00:00

abstract：:The traditional auscultatory technique and current methodologies for measuring human blood pressure are limited when used in situations where extreme vibration or acoustic noise is present. In this study, human subjects were used to establish the effectiveness of a novel adaptive blood pressure monitoring (ABPM) syste...

journal_title：Annals of biomedical engineering

authors： Pinto L,Dhanantwari A,Wong W,Stergiopoulos S,Maris M

更新日期：2002-05-01 00:00:00

abstract：:The linear homeomorphic muscle model proposed by Enderle and coworkers for the rectus eye muscle is fitted to reflect the dynamics of muscles in the head-neck complex, specifically in muscles involved in gaze shifts. This parameterization of the model for different muscles in the neck region will serve to drive a 3D d...

journal_title：Annals of biomedical engineering

authors： Sierra DA,Enderle JD

更新日期：2010-02-01 00:00:00

abstract：:Therapeutic irradiation is commonly used in the treatment of malignant brain tumors and has the potential to cause severe injury to normal tissues adjacent to a lesion. Computed tomography (CT) can be used not only to visualize tissue damage but to monitor the development of a lesion using advanced quantitative CT tec...

journal_title：Annals of biomedical engineering

authors： Russell LB,Fike JR,Cann CE,Süsskind C

更新日期：1984-01-01 00:00:00

abstract：:Transient homotypic adhesions between flowing leukocytes and those previously adherent on the vessel wall has been proposed to amplify the accumulation of leukocytes at sites of inflammation. While adhesion of leukocytes to the vessel wall (primary capture) is mediated primarily by P-selectin on the endothelium and P-...

journal_title：Annals of biomedical engineering

authors： Paschall CD,Lawrence MB

更新日期：2008-04-01 00:00:00

abstract：:Asymmetric 75% and 95% area reduction, transparent Sylgard stenotic models were operated under internal carotid artery (ICA) [Womersley parameter, alpha=5.36, Re(mean) =213 and 180, respectively, and Re(peak)=734 and 410, respectively] and left anterior descending coronary artery (LAD) flow wave forms (alpha=2.65, Re(...

journal_title：Annals of biomedical engineering

authors： Cao J,Rittgers SE

更新日期：1998-03-01 00:00:00

abstract：:The measurement of CO2 volume exhaled per breath (VCO2.br) can be determined during anesthesia by the multiplication and integration of tidal flow (V) and PCO2. During side-stream capnometry, PCO2 must be advanced in time by transport delay (TD), the time to suction gas through the sampling tube. During ventilation, T...

journal_title：Annals of biomedical engineering

authors： Breen PH,Serina ER

更新日期：1997-01-01 00:00:00

abstract：:Hemodynamic parameters play an important role in regulating vascular remodeling in arterio-venous fistula (AVF) maturation. Investigating the changes in hemodynamic parameters during AVF maturation is expected to improve our understanding of fistula failure, but very little data on actual temporal changes in human AVF...

journal_title：Annals of biomedical engineering

authors： Sigovan M,Rayz V,Gasper W,Alley HF,Owens CD,Saloner D

更新日期：2013-04-01 00:00:00

abstract：:The nonlinear diffusion-reaction equations describing the nonequilibrium transport of CO2 through flat layers of complex but homogeneous aqueous media were solved by an approximate analytical method called the "Combined Damköhler Number" (CDN) technique. Unlike other approximate analytical solutions, the CDN technique...

journal_title：Annals of biomedical engineering

authors： Hoofd LJ,Tong RR,Stroeve P

更新日期：1986-01-01 00:00:00