Modeling Human Volunteers in Multidirectional, Uni-axial Sled Tests Using a Finite Element Human Body Model.

abstract：:Previous research in cellular adhesion has focused primarily on studying isolated cells under conditions where cells do not interact with each other. However, in vivo cells form sheets where both cell-substratum and cell-cell interactions contribute to the overall adhesive behavior. Our understanding of how cell-cell ...

journal_title：Annals of biomedical engineering

authors： Peel MM,DiMilla PA

更新日期：1999-03-01 00:00:00

abstract：:Microfluidic devices aim at miniaturizing, automating, and lowering the cost of chemical and biological sample manipulation and detection, hence creating new opportunities for lab-on-a-chip platforms. Recently, optofluidic devices have also emerged where optics is used to enhance the functionality and the performance ...

journal_title：Annals of biomedical engineering

authors： Bishara W,Isikman SO,Ozcan A

更新日期：2012-02-01 00:00:00

abstract：:The strength between the cortical screw and bone following an orthopaedic implant surgery is an important determinant for the success of osteosynthesis. An excessive axial cutting force during drilling produces microcracks in the bone surface, resulting in reduced strength between the screw and bone, resulting in loos...

journal_title：Annals of biomedical engineering

authors： Singh RP,Gupta V,Pandey PM,Mridha AR

更新日期：2021-01-01 00:00:00

abstract：:Mechanical ventilation is a life-support therapy for intensive care patients suffering from respiratory failure. To reduce the current rate of ventilator-induced lung injury requires ventilator settings that are patient-, time-, and disease-specific. A common lung protective strategy is to optimise the level of positi...

journal_title：Annals of biomedical engineering

authors： Morton SE,Knopp JL,Chase JG,Möller K,Docherty P,Shaw GM,Tawhai M

更新日期：2019-07-01 00:00:00

abstract：:A cohesive zone model (CZM) approach is applied to simulate atherosclerotic plaque delamination experiments in mouse abdominal aorta specimens. A three-dimensional finite element model is developed for the experiments. The aortic wall is treated as a fiber-reinforced, highly deformable, incompressible material, and th...

journal_title：Annals of biomedical engineering

authors： Leng X,Chen X,Deng X,Sutton MA,Lessner SM

更新日期：2015-12-01 00:00:00

abstract：:Impedance cardiography has not achieved popularity in the Intensive Care Unit (ICU) to date probably because of the limitations in technique and interpretation associated with the altered physiology of critically ill patients, and also because of interference from other machinery in the ICU. The current climate of que...

journal_title：Annals of biomedical engineering

authors： Fuller H,Raskob G,ter Keurs H,Hull R

更新日期：1989-01-01 00:00:00

abstract：:The geometric and hemodynamic characteristics of the left and right vertebral arteries (LVA, RVA) of six healthy volunteers were investigated for the supine (S) and the prone position (P) a common sleeping posture with head rotation. MRI images were used to reconstruct the subject specific three-dimensional solid mode...

journal_title：Annals of biomedical engineering

authors： Aristokleous N,Seimenis I,Georgiou GC,Nicolaides A,Anayiotos AS

更新日期：2015-06-01 00:00:00

abstract：:The Veterans Health Administration determined that over 250,000 U.S. service members were diagnosed with a traumatic brain injury (TBI) between 2008 and 2018, of which a great proportion were due to blast exposure. Although the penetrating (secondary) and inertia-driven (tertiary) phases of blast-induced TBI (bTBI) ha...

journal_title：Annals of biomedical engineering

authors： Vogel EW 3rd,Panzer MB,Morales FN,Varghese N,Bass CR,Meaney DF,Morrison B 3rd

更新日期：2020-04-01 00:00:00

abstract：:Predictions from biomechanical models of gait may be sensitive to joint center locations. Most often, the hip joint center (HJC) is derived from locations of reflective markers adhered to the skin. Here, predictive techniques use regression equations of pelvic anatomy to estimate the HJC, whereas functional methods tr...

journal_title：Annals of biomedical engineering

authors： Fiorentino NM,Kutschke MJ,Atkins PR,Foreman KB,Kapron AL,Anderson AE

更新日期：2016-07-01 00:00:00

abstract：:Congenital heart disease is the leading cause of infant death in the United States with over 36,000 newborns affected each year. Despite this growing problem there are few mechanical circulatory support devices designed specifically for pediatric and neonate patients. Previous research has been done investigating pedi...

journal_title：Annals of biomedical engineering

authors： Good BC,Deutsch S,Manning KB

更新日期：2016-04-01 00:00:00

abstract：:Irreversible electroporation (IRE), is a new non-thermal tissue ablation technology in which brief high electric field pulses are delivered across the target tissue to induce cell death by irreversible permeabilization of the cell membrane. A deficiency of conventional IRE is that the ablation zone is relatively small...

journal_title：Annals of biomedical engineering

authors： Lv Y,Yao C,Rubinsky B

更新日期：2019-07-01 00:00:00

abstract：:This project was undertaken to establish if the integral circulation had any effects upon the mechanical behavior of bone. The influence of blood flow in the rabbit tibia on the strain induced at the bone surface when under load was assessed. Recordings were taken from three adult and three immature New Zealand White ...

journal_title：Annals of biomedical engineering

authors： McDonald F,Pitt Ford TR

更新日期：1994-03-01 00:00:00

abstract：:It is proposed that the maximum in cuff pressure oscillations during oscillometry is due to the buckling of the brachial artery under a cuff. This theory is investigated by means of a mathematical model of oscillatometry that includes the mechanics of the occlusive arm cuff, the arterial pressure pulse waveform, and t...

journal_title：Annals of biomedical engineering

authors： Drzewiecki G,Hood R,Apple H

更新日期：1994-01-01 00:00:00

abstract：:Pressure ulcer risk assessment might be optimized by incorporating the soft tissue reaction to mechanical loading in the currently used risk assessment scales. Cytokines, like IL-1alpha, IL-1RA, IL-8, and TNF-alpha, might be used to determine this tissue reaction, since they are released after 24 h of mechanical loadi...

journal_title：Annals of biomedical engineering

authors： Cornelissen LH,Bronneberg D,Bader DL,Baaijens FP,Oomens CW

更新日期：2009-05-01 00:00:00

abstract：:Recent studies suggest that vortex ring formation during left ventricular (LV) rapid filling is an optimized mechanism for blood transport, and that the volume of the vortex ring is an important measure. However, due to lack of quantitative methods, the volume of the vortex ring has not previously been studied. Lagran...

journal_title：Annals of biomedical engineering

authors： Töger J,Kanski M,Carlsson M,Kovács SJ,Söderlind G,Arheden H,Heiberg E

更新日期：2012-12-01 00:00:00

abstract：:Calcium phosphate ceramics have been widely used for filling bone defects to aid in the regeneration of new bone tissue. Addition of osteogenic cells to porous ceramic scaffolds may accelerate the bone repair process. This study demonstrates the feasibility of culturing marrow stromal cells (MSCs) on porous biphasic c...

journal_title：Annals of biomedical engineering

authors： Holtorf HL,Sheffield TL,Ambrose CG,Jansen JA,Mikos AG

更新日期：2005-09-01 00:00:00

abstract：:The kidney is one of the most radiosensitive organs; it is the primary dose-limiting organ in radiotherapies for upper abdominal cancers. The role of mitochondrial redox state in the development and treatment of renal radiation injury, however, remains ill-defined. This study utilizes 3D optical cryo-imaging to quanti...

journal_title：Annals of biomedical engineering

authors： Mehrvar S,la Cour MF,Medhora M,Camara AKS,Ranji M

更新日期：2019-07-01 00:00:00

abstract：:A kinematic analysis of the temporomandibular joint (TMJ) is developed to determine the range of motion of the mandible during normal opening and during special motions required for arthroscopic surgery. The translation of the mandible is restricted by the constraint of the ligaments. By accounting for the maximum all...

journal_title：Annals of biomedical engineering

authors： Kang QS,Updike DP,Salathe EP

更新日期：1993-11-01 00:00:00

abstract：:Step-off edges and tissue interfaces are prevalent in cartilage injury such as after intra-articular fracture and reduction, and in focal defects and surgical repair procedures such as osteochondral graft implantation. It would be useful to assess the function of injured or donor tissues near such step-off edges and t...

journal_title：Annals of biomedical engineering

authors： Bae WC,Law AW,Amiel D,Sah RL

更新日期：2004-03-01 00:00:00

abstract：:In order to obtain the first quantitative measurements of the in vivo stresses in early-stage amphibian embryos, we developed a novel instrument that uses a pair of parallel wires that are glued to the surface of an embryo normal to the direction in which the stress is to be determined. When a slit is made parallel to...

journal_title：Annals of biomedical engineering

authors： Benko R,Brodland GW

更新日期：2007-04-01 00:00:00

abstract：:Finite element analysis is a powerful tool for investigating the biomechanics of atherosclerosis and has thereby provided an improved understanding of acute myocardial infarction. Structural analysis of arterial walls is traditionally performed using geometry contours derived from histology. In this paper we demonstra...

journal_title：Annals of biomedical engineering

authors： Chau AH,Chan RC,Shishkov M,MacNeill B,Iftimia N,Tearney GJ,Kamm RD,Bouma BE,Kaazempur-Mofrad MR

更新日期：2004-11-01 00:00:00

abstract：:Biomaterial-based tissue engineering strategies hold great promise for osteochondral tissue repair. Yet significant challenges remain in joining highly dissimilar materials to achieve a biomimetic, mechanically robust design for repairing interfaces between soft tissue and bone. This study sought to improve interfacia...

journal_title：Annals of biomedical engineering

authors： Kinneberg KR,Nelson A,Stender ME,Aziz AH,Mozdzen LC,Harley BA,Bryant SJ,Ferguson VL

更新日期：2015-11-01 00:00:00

abstract：:Dendritic cells (DCs) are crucial components of the immune response, strategically positioned as immune sentinels. Complex trafficking and accurate positioning of DCs are indispensable for both immunity and tolerance. This is particularly evident for their therapeutic application where an unmet clinical need exists fo...

journal_title：Annals of biomedical engineering

authors： Silva Z,Konstantopoulos K,Videira PA

更新日期：2012-04-01 00:00:00

abstract：:In vitro stent-induced thromboembolism was altered by the presence of residual stenoses placed upstream or placed upstream and downstream of the stent. Heparinized (3 micro/ml) bovine blood was gravity fed through a conduit with a deployed coronary stent. Embolism was continuously monitored using a light-scattering mi...

journal_title：Annals of biomedical engineering

authors： Sukavaneshvar S,Rosa GM,Solen KA

更新日期：2000-02-01 00:00:00

abstract：:Parameters of physiological models are commonly associated in an input-output experiment with a specific pattern of the system response. This association is often made on an intuitive basis by traditional sensitivity analysis, i.e., by inspecting the variations of model output trajectories with respect to parameter va...

journal_title：Annals of biomedical engineering

authors： Thomaseth K,Cobelli C

更新日期：1999-09-01 00:00:00

abstract：:The human thorax is commonly injured in motor vehicle crashes, and despite advancements in occupant safety rib fractures are highly prevalent. The objective of this study was to quantify the ability of gross and cross-sectional geometry, separately and in combination, to explain variation of human rib structural prope...

journal_title：Annals of biomedical engineering

authors： Murach MM,Kang YS,Goldman SD,Schafman MA,Schlecht SH,Moorhouse K,Bolte JH 4th,Agnew AM

更新日期：2017-09-01 00:00:00

abstract：:Continuous measurement of arterial blood density after bolus injection of fluids of different density into the right atrium has been used to measure cardiac output and mean transit time through the central circulation. The transit time distribution for density, however, differs from that for plasma-phase tracers such ...

journal_title：Annals of biomedical engineering

authors： Ligas JR,Moslehi F,Epstein MA

更新日期：1993-07-01 00:00:00

abstract：:Viscous shear stress and Reynolds stress are often used to predict hemolysis and thrombosis due to flow-induced stress on blood elements in cardiovascular devices. These macroscopic stresses are distinct from the true stress on an individual cell, which is determined by the local microscale flow field. In this paper t...

journal_title：Annals of biomedical engineering

authors： Quinlan NJ,Dooley PN

更新日期：2007-08-01 00:00:00

abstract：:Rapid screening of biomarkers, with high specificity and accuracy, is critical for many point-of-care diagnostics. Microfluidics, the use of microscale channels to manipulate small liquid samples and carry reactions in parallel, offers tremendous opportunities to address fundamental questions in biology and provide a ...

journal_title：Annals of biomedical engineering

authors： Ng E,Chen K,Hang A,Syed A,Zhang JX

更新日期：2016-04-01 00:00:00

abstract：:This paper reviews the applications of accelerometers on the detection of physiological acoustic signals such as heart sounds, respiratory sounds, and gastrointestinal sounds. These acoustic signals contain a rich reservoir of vital physiological and pathological information. Accelerometer-based systems enable continu...

journal_title：Annals of biomedical engineering

authors： Hu Y,Kim EG,Cao G,Liu S,Xu Y

更新日期：2014-11-01 00:00:00