Strontium ranelate prevents bone loss in a rat model of localized muscle paralysis.

abstract：:Tumor vasculature damage induced by various thermal treatments has been studied in vivo via laser confocal microscopy. Murine mammary carcinoma 4T1 was implanted in the nude mice dorsal skin fold window chamber. The implanted tumor was treated by alternate cooling and heating. Results showed that the treatment was muc...

journal_title：Annals of biomedical engineering

authors： Shen Y,Liu P,Zhang A,Xu LX

更新日期：2008-08-01 00:00:00

abstract：:The kidney is one of the most radiosensitive organs; it is the primary dose-limiting organ in radiotherapies for upper abdominal cancers. The role of mitochondrial redox state in the development and treatment of renal radiation injury, however, remains ill-defined. This study utilizes 3D optical cryo-imaging to quanti...

journal_title：Annals of biomedical engineering

authors： Mehrvar S,la Cour MF,Medhora M,Camara AKS,Ranji M

更新日期：2019-07-01 00:00:00

abstract：:Modern models of cardiac membranes are often highly complex and computationally expensive, particularly when used in long simulations of spatially extended models of cardiac tissue. Therefore, there is a need for simpler membrane models that preserve the features of the complex models deemed important. This communicat...

journal_title：Annals of biomedical engineering

authors： Oliver RA,Krassowska W

更新日期：2005-07-01 00:00:00

abstract：:This study is aimed at refining our understanding of the role of vortex formation at mitral mechanical heart valve (MHV) closure and its association with the high intensity transient signals (HITS) seen in echocardiographic studies with MHV recipients. Previously reported numerical results described a twofold process ...

journal_title：Annals of biomedical engineering

authors： Rambod E,Beizai M,Sahn DJ,Gharib M

更新日期：2007-07-01 00:00:00

abstract：:Cellular engineering applies the principles and methods of engineering to the problems of cell and molecular biology of both a basic and applied nature. As biomedical engineering has shifted from the organ and tissue level to the cellular and sub-cellular level, cellular engineering has emerged as a new area. A corner...

journal_title：Annals of biomedical engineering

authors： Nerem RM

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Common-mode noise degrades cardiovascular signal quality and diminishes measurement accuracy. Filtering to remove noise components in the frequency domain often distorts the signal. METHOD:Two adaptive noise canceling (ANC) algorithms were tested to adjust weighted reference signals for optimal subtraction ...

journal_title：Annals of biomedical engineering

authors： Ciaccio EJ,Micheli-Tzanakou E

更新日期：2007-07-01 00:00:00

abstract：:Image registration and motion estimation play central roles in many fields, including RADAR, SONAR, light microscopy, and medical imaging. Because of its central significance, estimator accuracy, precision, and computational cost are of critical importance. We have previously presented a highly accurate, spline-based ...

journal_title：Annals of biomedical engineering

authors： Viola F,Coe RL,Owen K,Guenther DA,Walker WF

更新日期：2008-12-01 00:00:00

abstract：:Deep tissue injury (DTI) is a type of pressure ulcer in which tissue breakdown initiates at the bone-muscle interface under intact skin. Excessive deformation in the soft tissue, particularly around bony prominences, is believed to be one of the causes leading to the development of DTI. The main goal of this study was...

journal_title：Annals of biomedical engineering

authors： Solis LR,Liggins AB,Seres P,Uwiera RR,Poppe NR,Pehowich E,Thompson RB,Mushahwar VK

更新日期：2012-08-01 00:00:00

abstract：:The influence of scaffold compliance on blood vessel tissue engineering remains unclear and compliance mismatch issues are important to an in vivo tissue-engineering approach. We have designed and constructed a modular bioreactor system that is capable of imparting pulsatile fluid flow while simultaneously measuring v...

journal_title：Annals of biomedical engineering

authors： Webb AR,Macrie BD,Ray AS,Russo JE,Siegel AM,Glucksberg MR,Ameer GA

更新日期：2007-08-01 00:00:00

abstract：:A multifunctional FePt nanoparticle was developed that targets tumor microvasculature via "radiation-guided" peptides, and is detected by both near-infrared (NIR) fluorescence imaging and analytical mass spectrometry methods. Tumor specific binding was first measured by biotinylated peptide linked to fluorophore-conju...

journal_title：Annals of biomedical engineering

authors： Hariri G,Wellons MS,Morris WH 3rd,Lukehart CM,Hallahan DE

更新日期：2011-03-01 00:00:00

abstract：:Identifying the associations between head impact biomechanics and clinical recovery may inform better head impact monitoring procedures and identify athletes who may benefit from early treatments aimed to enhance recovery. The purpose of this study was to test whether head injury biomechanics are associated with clini...

journal_title：Annals of biomedical engineering

authors： Mihalik JP,Chandran A,Powell JR,Roby PR,Guskiewicz KM,Stemper BD,Shah AS,Rowson S,Duma S,Harezlak J,Riggen L,Broglio SP,McAllister TW,McCrea M,CARE Consortium Investigators.

更新日期：2020-11-01 00:00:00

abstract：:The induction of angiogenesis is a promising therapeutic strategy for the amelioration of peripheral arterial disease (PAD). This occlusive disease results in muscle ischemia, and neovascularization is a route to increasing the perfusion in the tissue. The vascular endothelial growth factor (VEGF) family of potent pro...

journal_title：Annals of biomedical engineering

authors： Mac Gabhann F,Ji JW,Popel AS

更新日期：2007-06-01 00:00:00

abstract：:Although diagnostic testing with auditory evoked potentials (EPs) has become routine, quantitative measurements of signal and noise are still lacking. In this study, current signal, power, noise power, and signal-to-noise ratio (SNR) estimation formulas are reviewed and applied to auditory brainstem response averaging...

journal_title：Annals of biomedical engineering

authors： Ozdamar O,Delgado RE

更新日期：1996-11-01 00:00:00

abstract：:In uniaxial tensile testing, load preconditioning is used to generate repeatable load/elongation curves and set a "reference state" for subsequent tensile tests. We have observed however, that for porcine aortic valve (PAV) tissues, preconditioning does not lead to repeatable stress relaxation curves. We thus investig...

journal_title：Annals of biomedical engineering

authors： Carew EO,Garg A,Barber JE,Vesely I

更新日期：2004-04-01 00:00:00

abstract：:We develop a mathematical model of nanoparticles depositing onto and penetrating into a biofilm grown in a parallel-plate flow cell. We carry out deposition experiments in a flow cell to support the modeling. The modeling and the experiments are motivated by the potential use of polymer nanoparticles as part of a trea...

journal_title：Annals of biomedical engineering

authors： Miller JK,Neubig R,Clemons CB,Kreider KL,Wilber JP,Young GW,Ditto AJ,Yun YH,Milsted A,Badawy HT,Panzner MJ,Youngs WJ,Cannon CL

更新日期：2013-01-01 00:00:00

abstract：:The efforts to develop structural materials for biodegradable metal implants have lately shifted their focus from Magnesium and Iron base alloys towards Zinc. This was mainly due to the accelerated corrosion rate of Mg that is accompanied by hydrogen gas evolution, formation of voluminous iron oxide products with redu...

journal_title：Annals of biomedical engineering

authors： Kafri A,Ovadia S,Yosafovich-Doitch G,Aghion E

更新日期：2019-06-01 00:00:00

abstract：:The function of a chamber depends on its hydrodynamic properties: isometric pressures it can exert in the operating range of distensions, compliances in the operating range of distensions, and wall-displacement resistances in the operating range of distensions. Wall-displacement resistance is the departure of pressure...

journal_title：Annals of biomedical engineering

authors： Regen DM

更新日期：1988-01-01 00:00:00

abstract：:Electrospinning was used in innovative electrospinning rigs to obtain tubular and flat fibrous structures with controlled fiber orientation with the aim to be used as scaffolds for biomedical applications, more specifically in the tissue engineering of vascular and orthopedic grafts. Gelatine and hydroxyapatite (HA)-g...

journal_title：Annals of biomedical engineering

authors： Salifu AA,Nury BD,Lekakou C

更新日期：2011-10-01 00:00:00

abstract：:Collagen, the most commonly used extra-cellular matrix protein for tissue engineering applications, displays poor mechanical properties. Here, we report on the preparation and characterization of novel multi-component composite systems that incorporate a genetically engineered, biocompatible polymer (elastin-like poly...

journal_title：Annals of biomedical engineering

authors： Wheeler TS,Sbravati ND,Janorkar AV

更新日期：2013-10-01 00:00:00

abstract：:Viscous shear stress and Reynolds stress are often used to predict hemolysis and thrombosis due to flow-induced stress on blood elements in cardiovascular devices. These macroscopic stresses are distinct from the true stress on an individual cell, which is determined by the local microscale flow field. In this paper t...

journal_title：Annals of biomedical engineering

authors： Quinlan NJ,Dooley PN

更新日期：2007-08-01 00:00:00

abstract：:It is well known that neutrophils take much longer to traverse the pulmonary capillary bed than erythrocytes, and this is likely due to differences in the structure and rheology of the cells. In this study, we simulate the transit of a neutrophil in a capillary using a Newtonian drop model and a viscoelastic drop mode...

journal_title：Annals of biomedical engineering

authors： Zhou C,Yue P,Feng JJ

更新日期：2007-05-01 00:00:00

abstract：:One goal of large scale clinical trials is to determine how a drug is processed by, and cleared from, the human body [i.e., its pharmacokinetic (PK) properties] and how these PK properties differ between individuals in a population (i.e., its population PK properties). Due to the high cost of these studies and the lim...

journal_title：Annals of biomedical engineering

authors： Hooker AC,Foracchia M,Dodds MG,Vicini P

更新日期：2003-01-01 00:00:00

abstract：:Articular cartilage is an avascular connective tissue responsible for bearing loads. Cell signaling plays a central role in cartilage homeostasis and tissue engineering by directing chondrocytes to synthesize/degrade the extracellular matrix or promote inflammatory responses. The aim of this paper was to investigate a...

journal_title：Annals of biomedical engineering

authors： Neidlin M,Korcari A,Macheras G,Alexopoulos LG

更新日期：2018-02-01 00:00:00

abstract：:Defibrillation efficacy testing is a common procedure at defibrillator implantation, with the objective to ensure that each patient receives a system with adequate shock efficacy. In this study, defibrillation shock efficacy as a function of shock energy was modeled by a dose response relationship. The frequency distr...

journal_title：Annals of biomedical engineering

authors： Smits K,Virag N

更新日期：2010-04-01 00:00:00

abstract：:Therapeutic irradiation is commonly used in the treatment of malignant brain tumors and has the potential to cause severe injury to normal tissues adjacent to a lesion. Computed tomography (CT) can be used not only to visualize tissue damage but to monitor the development of a lesion using advanced quantitative CT tec...

journal_title：Annals of biomedical engineering

authors： Russell LB,Fike JR,Cann CE,Süsskind C

更新日期：1984-01-01 00:00:00

abstract：:Naphthalene is a toxicant with unusual species and tissue specificity that has been the subject of in vitro studies. We describe a preliminary physiologically based pharmacokinetic (PBPK) model for naphthalene constructed solely from in vitro data for comparison to animal data without the use of adjustable parameters....

journal_title：Annals of biomedical engineering

authors： Sweeney LM,Shuler ML,Quick DJ,Babish JG

更新日期：1996-03-01 00:00:00

abstract：:In an effort to share best practices in undergraduate engineering design education, we describe the origin, evolution and the current status of the undergraduate biomedical engineering design team program at Johns Hopkins University. Specifically, we describe the program and judge the quality of the pedagogy by relati...

journal_title：Annals of biomedical engineering

authors： Allen RH,Acharya S,Jancuk C,Shoukas AA

更新日期：2013-09-01 00:00:00

abstract：:Classically, the primary tool for quantifying the dynamics of vergence and other eye movements has been the main sequence. The main sequence is a plot of peak velocity versus response amplitude and is particularly useful for comparing the dynamics of a large number of eye movements over a range of response amplitudes....

journal_title：Annals of biomedical engineering

authors： Alvarez TL,Semmlow JL,Yuan W,Munoz P

更新日期：1999-05-01 00:00:00

abstract：:Coronary artery bypass graft (CABG) failure has been linked to graft hemodynamics, in particular wall shear stress. This study characterizes the morphology, geometry and wall shear stress patterns in human CABGs. The intimal thickness (IT) in 49 human saphenous vein CABGs was measured by digital light microscopy. The ...

journal_title：Annals of biomedical engineering

authors： Leask RL,Butany J,Johnston KW,Ethier CR,Ojha M

更新日期：2005-03-01 00:00:00

abstract：:Microfluidic devices aim at miniaturizing, automating, and lowering the cost of chemical and biological sample manipulation and detection, hence creating new opportunities for lab-on-a-chip platforms. Recently, optofluidic devices have also emerged where optics is used to enhance the functionality and the performance ...

journal_title：Annals of biomedical engineering

authors： Bishara W,Isikman SO,Ozcan A

更新日期：2012-02-01 00:00:00