Electrocorticography links human temporoparietal junction to visual perception.

abstract：:In the version of this article initially published online, the accession code was given as GSE1000333. The correct code is GSE100033. The error has been corrected in the print, HTML and PDF versions of the article. ...

journal_title：Nature neuroscience

authors： Preissl S,Fang R,Huang H,Zhao Y,Raviram R,Gorkin DU,Zhang Y,Sos BC,Afzal V,Dickel DE,Kuan S,Visel A,Pennacchio LA,Zhang K,Ren B

更新日期：2018-07-01 00:00:00

abstract：:Neuronal migration disorders such as lissencephaly and subcortical band heterotopia are associated with epilepsy and intellectual disability. DCX, PAFAH1B1 and TUBA1A are mutated in these disorders; however, corresponding mouse mutants do not show heterotopic neurons in the neocortex. In contrast, spontaneously arisen...

journal_title：Nature neuroscience

authors： Kielar M,Tuy FP,Bizzotto S,Lebrand C,de Juan Romero C,Poirier K,Oegema R,Mancini GM,Bahi-Buisson N,Olaso R,Le Moing AG,Boutourlinsky K,Boucher D,Carpentier W,Berquin P,Deleuze JF,Belvindrah R,Borrell V,Welker E,Chel

更新日期：2014-07-01 00:00:00

abstract：:Midbrain ventral tegmental neurons project to the prefrontal cortex and modulate cognitive functions. Using viral tracing, optogenetics and electrophysiology, we found that mesocortical neurons in the mouse ventrotegmental area provide fast glutamatergic excitation of GABAergic interneurons in the prefrontal cortex an...

journal_title：Nature neuroscience

authors： Kabanova A,Pabst M,Lorkowski M,Braganza O,Boehlen A,Nikbakht N,Pothmann L,Vaswani AR,Musgrove R,Di Monte DA,Sauvage M,Beck H,Blaess S

更新日期：2015-06-01 00:00:00

abstract：:Nucleus accumbens (NAc) dopamine is widely implicated in mediating the reinforcing effects of drugs of abuse. However, the precise function of the NAc itself in drug self-administration has been difficult to establish. Here we show a neural double-dissociation of the behavioral processes that underlie cocaine self-adm...

journal_title：Nature neuroscience

authors： Ito R,Robbins TW,Everitt BJ

更新日期：2004-04-01 00:00:00

abstract：:Most neurons in macaque area MT are selective for the direction of stimulus motion. By comparing direction selectivity for gratings and plaids, we classified MT neurons as pattern direction selective (PDS) or component direction selective (CDS). We compared the time course of responses in CDS and PDS neurons in opiate...

journal_title：Nature neuroscience

authors： Smith MA,Majaj NJ,Movshon JA

更新日期：2005-02-01 00:00:00

abstract：:The precise period when experience shapes neural circuits in the mouse visual system is unknown. We used Arc induction to monitor the functional pattern of ipsilateral eye representation in cortex during normal development and after visual deprivation. After monocular deprivation during the critical period, Arc induct...

journal_title：Nature neuroscience

authors： Tagawa Y,Kanold PO,Majdan M,Shatz CJ

更新日期：2005-03-01 00:00:00

abstract：:Visual information is delivered to the brain by >40 types of retinal ganglion cells (RGCs). Diversity in this representation arises within the inner plexiform layer (IPL), where dendrites of each RGC type are restricted to specific sublaminae, limiting the interneuronal types that can innervate them. How such dendriti...

journal_title：Nature neuroscience

authors： Liu J,Reggiani JDS,Laboulaye MA,Pandey S,Chen B,Rubenstein JLR,Krishnaswamy A,Sanes JR

更新日期：2018-05-01 00:00:00

abstract：:The growth of neurites (axon and dendrite) should be appropriately regulated by their interactions in the development of nervous systems where a myriad of neurons and their neurites are tightly packed. We show here that mammalian seven-pass transmembrane cadherins Celsr2 and Celsr3 are activated by their homophilic in...

journal_title：Nature neuroscience

authors： Shima Y,Kawaguchi SY,Kosaka K,Nakayama M,Hoshino M,Nabeshima Y,Hirano T,Uemura T

更新日期：2007-08-01 00:00:00

abstract：:The ventral intraparietal area (VIP) receives converging inputs from visual, somatosensory, auditory and vestibular systems that use diverse reference frames to encode sensory information. A key issue is how VIP combines those inputs together. We mapped the visual and tactile receptive fields of multimodal VIP neurons...

journal_title：Nature neuroscience

authors： Avillac M,Denève S,Olivier E,Pouget A,Duhamel JR

更新日期：2005-07-01 00:00:00

abstract：:Many neural signaling receptors are regulated by endocytosis, but little is known about receptor insertion into the plasma membrane. Time-lapse imaging of the beta2 adrenergic receptor expressed in cultured rat hippocampal neurons, using pH-sensitive green fluorescent protein tagging and total internal reflection fluo...

journal_title：Nature neuroscience

authors： Yudowski GA,Puthenveedu MA,von Zastrow M

更新日期：2006-05-01 00:00:00

abstract：:Repeated cocaine administration increases the dendritic arborization of nucleus accumbens neurons, but the underlying signaling events remain unknown. Here we show that repeated exposure to cocaine negatively regulates the active form of Rac1, a small GTPase that controls actin remodeling in other systems. Further, we...

journal_title：Nature neuroscience

authors： Dietz DM,Sun H,Lobo MK,Cahill ME,Chadwick B,Gao V,Koo JW,Mazei-Robison MS,Dias C,Maze I,Damez-Werno D,Dietz KC,Scobie KN,Ferguson D,Christoffel D,Ohnishi Y,Hodes GE,Zheng Y,Neve RL,Hahn KM,Russo SJ,Nestler EJ

更新日期：2012-06-01 00:00:00

abstract：:The melanocortin system provides a conceptual blueprint for the central control of energetic state. Defined by four principal molecular components--two antagonistically acting ligands and two cognate receptors--this phylogenetically conserved system serves as a prototype for hierarchical energy balance regulation. Ove...

journal_title：Nature neuroscience

authors： Krashes MJ,Lowell BB,Garfield AS

更新日期：2016-02-01 00:00:00

abstract：:Cuing covert spatial attention can increase spatial resolution. Here we pinpointed the specific locus of this effect using texture segmentation. At the level of visual cortex, texture segmentation theoretically involves passage of visual input through two layers of spatial linear filters separated by a pointwise nonli...

journal_title：Nature neuroscience

authors： Yeshurun Y,Carrasco M

更新日期：2000-06-01 00:00:00

abstract：:In Huntington's disease (HD), expansion of CAG codons in the huntingtin gene (HTT) leads to the aberrant formation of protein aggregates and the differential degeneration of striatal medium spiny neurons (MSNs). Modeling HD using patient-specific MSNs has been challenging, as neurons differentiated from induced plurip...

journal_title：Nature neuroscience

authors： Victor MB,Richner M,Olsen HE,Lee SW,Monteys AM,Ma C,Huh CJ,Zhang B,Davidson BL,Yang XW,Yoo AS

更新日期：2018-03-01 00:00:00

abstract：:An action may lead to either a reward or a punishment. Therefore, an appropriate action needs to be chosen on the basis of the values of both expected rewards and expected punishments. To understand the underlying neural mechanisms, we conditioned monkeys using a Pavlovian procedure with two distinct contexts: one in ...

journal_title：Nature neuroscience

authors： Matsumoto M,Hikosaka O

更新日期：2009-01-01 00:00:00

abstract：:Processing of rapidly successive acoustic stimuli can be markedly improved by sensory training. To investigate the cortical mechanisms underlying such temporal plasticity, we trained rats in a 'sound maze' in which navigation using only auditory cues led to a target location paired with food reward. In this task, the ...

journal_title：Nature neuroscience

authors： Bao S,Chang EF,Woods J,Merzenich MM

更新日期：2004-09-01 00:00:00

abstract：:We examined enhancement of synaptic transmission by neurotrophins at the presynaptic level. In a synaptosomal preparation, brain-derived neurotrophic factor (BDNF) increased mitogen-activated protein (MAP) kinase-dependent synapsin I phosphorylation and acutely facilitated evoked glutamate release. PD98059, used to in...

journal_title：Nature neuroscience

authors： Jovanovic JN,Czernik AJ,Fienberg AA,Greengard P,Sihra TS

更新日期：2000-04-01 00:00:00

abstract：:Cue-triggered recall of learned temporal sequences is an important cognitive function that has been attributed to higher brain areas. Here recordings in both anesthetized and awake rats demonstrate that after repeated stimulation with a moving spot that evoked sequential firing of an ensemble of primary visual cortex ...

journal_title：Nature neuroscience

authors： Xu S,Jiang W,Poo MM,Dan Y

更新日期：2012-01-22 00:00:00

abstract：:Microglia, the brain's intrinsic immune cells, rapidly sense brain injury and help clear cellular debris. Haynes et al. now show that P2Y12 receptors are critical for activating microglia and directing them to the site of injury. ...

journal_title：Nature neuroscience

authors： Kettenmann H

更新日期：2006-12-01 00:00:00

abstract：:Active sensation requires the convergence of external stimuli with representations of body movements. We used mouse behavior, electrophysiology and optogenetics to dissect the temporal interactions among whisker movement, neural activity and sensation of touch. We photostimulated layer 4 activity in single barrels in ...

journal_title：Nature neuroscience

authors： O'Connor DH,Hires SA,Guo ZV,Li N,Yu J,Sun QQ,Huber D,Svoboda K

更新日期：2013-07-01 00:00:00

abstract：:The painful sensations produced by a laceration, freeze, burn, muscle strain or internal injury are readily distinguishable because each is characterized by a particular sensory quality such as sharp, aching, burning or prickling. We propose that there are specific neural correlates of each pain quality, and here we u...

journal_title：Nature neuroscience

authors： Davis KD,Pope GE,Crawley AP,Mikulis DJ

更新日期：2002-11-01 00:00:00

abstract：:Autism spectrum disorder (ASD) is genetically heterogeneous with convergent symptomatology, suggesting common dysregulated pathways. In this study, we analyzed brain transcriptional changes in five mouse models of Pitt-Hopkins syndrome (PTHS), a syndromic form of ASD caused by mutations in the TCF4 gene, but not the T...

journal_title：Nature neuroscience

authors： Phan BN,Bohlen JF,Davis BA,Ye Z,Chen HY,Mayfield B,Sripathy SR,Cerceo Page S,Campbell MN,Smith HL,Gallop D,Kim H,Thaxton CL,Simon JM,Burke EE,Shin JH,Kennedy AJ,Sweatt JD,Philpot BD,Jaffe AE,Maher BJ

更新日期：2020-03-01 00:00:00

abstract：:Hippocampal long-term potentiation (LTP) induced by theta-burst pairing of Schaffer collateral inputs and postsynaptic firing is associated with localized increases in synaptic strength and dendritic excitability. Using the same protocol, we now demonstrate a decrease in cellular excitability that was blocked by the h...

journal_title：Nature neuroscience

authors： Fan Y,Fricker D,Brager DH,Chen X,Lu HC,Chitwood RA,Johnston D

更新日期：2005-11-01 00:00:00

abstract：:Synaptic stimulation activates signal transduction pathways, producing persistently active protein kinases. PKMzeta is a truncated, persistently active isoform of atypical protein kinase C-zeta (aPKCzeta), which lacks the N-terminal pseudosubstrate regulatory domain. Using a Pavlovian olfactory learning task in Drosop...

journal_title：Nature neuroscience

authors： Drier EA,Tello MK,Cowan M,Wu P,Blace N,Sacktor TC,Yin JC

更新日期：2002-04-01 00:00:00

abstract：:The cortical nucleus LMAN (lateral magnocellular nucleus of the anterior nidopallium) provides the output of a basal ganglia pathway that is necessary for vocal learning in juvenile songbirds. The shell subregion of LMAN (LMAN(shell)) gives rise to recurrent loops that may subserve specific learning-related functions....

journal_title：Nature neuroscience

authors： Bottjer SW,Altenau B

更新日期：2010-02-01 00:00:00

abstract：:Tumor-associated macrophages (TAMs) play an important role in the immune response to cancer, but the mechanisms by which the tumor microenvironment controls TAMs and T cell immunity are not completely understood. Here we report that kynurenine produced by glioblastoma cells activates aryl hydrocarbon receptor (AHR) in...

journal_title：Nature neuroscience

authors： Takenaka MC,Gabriely G,Rothhammer V,Mascanfroni ID,Wheeler MA,Chao CC,Gutiérrez-Vázquez C,Kenison J,Tjon EC,Barroso A,Vandeventer T,de Lima KA,Rothweiler S,Mayo L,Ghannam S,Zandee S,Healy L,Sherr D,Farez MF,Prat A,

更新日期：2019-05-01 00:00:00

abstract：:Sharp wave-ripple (SPW-R) complexes in the hippocampus-entorhinal cortex are believed to be important for transferring labile memories from the hippocampus to the neocortex for long-term storage. We found that selective elimination of SPW-Rs during post-training consolidation periods resulted in performance impairment...

journal_title：Nature neuroscience

authors： Girardeau G,Benchenane K,Wiener SI,Buzsáki G,Zugaro MB

更新日期：2009-10-01 00:00:00

abstract：:The weight of synaptic connections, which is controlled not only postsynaptically but also presynaptically, is a key determinant in neuronal network dynamics. The mechanisms controlling synaptic weight, especially on the presynaptic side, remain elusive. Using single-synapse imaging of the neurotransmitter glutamate c...

journal_title：Nature neuroscience

authors： Sakamoto H,Ariyoshi T,Kimpara N,Sugao K,Taiko I,Takikawa K,Asanuma D,Namiki S,Hirose K

更新日期：2018-01-01 00:00:00

abstract：:In the version of this article initially published, the traces in Fig. 1j and in Fig. 1k, right, were duplicated from the corresponding traces in Fig. 1c, bottom, and Fig. 1d, bottom right. The error has been corrected in the HTML and PDF versions of the article. ...

journal_title：Nature neuroscience

authors： Marek R,Jin J,Goode TD,Giustino TF,Wang Q,Acca GM,Holehonnur R,Ploski JE,Fitzgerald PJ,Lynagh T,Lynch JW,Maren S,Sah P

更新日期：2018-09-01 00:00:00

abstract：:Class I histone deacetylases (HDACs) Hdac1 and Hdac2 can associate together in protein complexes with transcriptional factors such as methyl-CpG-binding protein 2 (MeCP2). Given their high degree of sequence identity, we examined whether Hdac1 and Hdac2 were functionally redundant in mature mouse brain. We demonstrate...

journal_title：Nature neuroscience

authors： Mahgoub M,Adachi M,Suzuki K,Liu X,Kavalali ET,Chahrour MH,Monteggia LM

更新日期：2016-11-01 00:00:00