Essential role of nitric oxide in descending inhibition in the rat proximal colon.

abstract：:The intrapancreatic neuropeptide galanin has been demonstrated to lower plasma insulin levels in vivo. The effects of this peptide on insulin secretion, cytoplasmic free Ca2+ concentration and membrane potential have now been studied in vitro. Glucose-stimulated insulin secretion was inhibited by galanin under these c...

journal_title：Biochemical and biophysical research communications

authors： Ahrén B,Arkhammar P,Berggren PO,Nilsson T

更新日期：1986-11-14 00:00:00

abstract：:Myxothiazol is a respiratory chain complex III (CIII) inhibitor that binds to the ubiquinol oxidation site Qo of CIII. It blocks electron transfer from ubiquinol to cytochrome b and thus inhibits CIII activity. It has been utilized as a tool in studies of respiratory chain function in in vitro and cell culture models....

journal_title：Biochemical and biophysical research communications

authors： Davoudi M,Kallijärvi J,Marjavaara S,Kotarsky H,Hansson E,Levéen P,Fellman V

更新日期：2014-04-18 00:00:00

abstract：:p202, an interferon (IFN) inducible protein, is a phosphonuclear protein involved in the regulation of cell cycle, apoptosis, and differentiation. E2F1 belongs to the E2F family of proteins that are important cell cycle regulators in promoting cell growth. On the other hand, the deregulated expression of E2F1 also tri...

journal_title：Biochemical and biophysical research communications

authors： Yan DH,Abramian A,Li Z,Ding Y,Wen Y,Liu TJ,Hunt K

更新日期：2003-03-28 00:00:00

abstract：:Transglutaminase inhibitor (1,3,4,5-tetramethyl-2-[(2-oxopropyl)thio]imidazolium chloride or L-682777) affected the appearance of the fertilization envelope (FE) and subsequent development in Sphaerechinus granularis and Arbacia punctulata in a concentration-dependent manner. Abnormalities were first visible in formin...

journal_title：Biochemical and biophysical research communications

authors： Cariello L,Zanetti L,Lorand L

更新日期：1994-11-30 00:00:00

abstract：:Satellite cells that reside on the myofibre surface are crucial for the muscle homeostasis and regeneration. Aging goes along with a less effective regeneration of skeletal muscle tissue mainly due to the decreased myogenic capability of satellite cells. This phenomenon impedes proper maintenance and contributes to th...

journal_title：Biochemical and biophysical research communications

authors： Di Filippo ES,Mancinelli R,Pietrangelo T,La Rovere RM,Quattrocelli M,Sampaolesi M,Fulle S

更新日期：2016-04-29 00:00:00

abstract：:α-Isopropylmalate synthase (α-IPMS) is a multi-domain protein catalysing the condensation of α-ketoisovalerate (α-KIV) and acetyl coenzyme A (AcCoA) to form α-isopropylmalate. This reaction is the first committed step in the leucine biosynthetic pathway in bacteria and plants, and α-IPMS is allosterically regulated by...

journal_title：Biochemical and biophysical research communications

authors： Huisman FH,Squire CJ,Parker EJ

更新日期：2013-04-05 00:00:00

abstract：:SND p102 is a rat liver endoplasmic reticulum cholesterol ester hydrolase recently described as a member of a conserved family of transcriptional coactivators that promotes phospholipid secretion into lipoproteins when overexpressed in hepatocytes. In this work, we report first evidence for a mechanism of transcriptio...

journal_title：Biochemical and biophysical research communications

authors： Rodríguez L,Ochoa B,Martínez MJ

更新日期：2007-04-27 00:00:00

abstract：:The stage V sporulation protein G (SpoVG) homolog of Staphylococcus aureus is a modulator of virulence factor synthesis and antibiotic resistance in this clinically important gram-positive pathogen. Here we demonstrate that SpoVG can be phosphorylated by the staphylococcal Ser/Thr protein kinase Stk1 and that phosphor...

journal_title：Biochemical and biophysical research communications

authors： Bischoff M,Brelle S,Minatelli S,Molle V

更新日期：2016-05-13 00:00:00

abstract：:Engelbreth-Holm-Swarm (EHS) gel has been reported to maintain the mature hepatocyte phenotypes in primary cultured hepatocytes. We investigated the effect of EHS gel on the differentiation of fetal liver cells, which contain stem/progenitor cells. The isolated fetal liver cells cultured on EHS gel formed a spherical s...

journal_title：Biochemical and biophysical research communications

authors： Tsukada Y,Nagaki M,Suetsugu A,Osawa Y,Moriwaki H

更新日期：2009-04-17 00:00:00

abstract：:Exposure of rat atrial slices to 10(-5) M norepinephrine (NE) for 10 minutes increases 45Ca++ accumulation from 1.64 +/- 0.10 to 2.23 +/- 0.06 nmol/mg tissue. In the presence of leucine enkephalin (10(-8) M), NE-stimulated 45Ca++ uptake is reduced to 1.44 +/- 0.10 nmol/mg tissue. The effect of leu-enkephalin is revers...

journal_title：Biochemical and biophysical research communications

authors： Ruth JA,Cuizon JV,Eiden LE

更新日期：1983-12-16 00:00:00

abstract：:Pyrene, a structural analog of benzo[a]pyrene, is an effective competing ligand for high affinity carcinogen binding proteins in mouse liver. A pyrene-derivatized Sepharose gel was prepared for affinity chromatography purification of these proteins, and adsorbs all detectable [3H]B[a]P-binding activity from hepatic cy...

journal_title：Biochemical and biophysical research communications

authors： Collins S,Altman JD,Marletta MA

更新日期：1985-05-31 00:00:00

abstract：:Spontaneous Arg- mutants arose at high frequencies in Streptomyces lividans. Exposure to ethidium bromide increased the frequency of arg instability. In Pro+ strains the induced arg mutants were mainly argG, but in the proB mutants, a new mutation, argJ, prevailed which lacked ornithine acetyltransferase activity and ...

journal_title：Biochemical and biophysical research communications

authors： Chou CF,Chen CW

更新日期：1992-12-15 00:00:00

abstract：:While recent insights indicate that the transcription factor Krüppel-like factor 4 (KLF4) is indispensable for vascular homeostasis, its exact role in proliferation and angiogenesis and how it functions remain unresolved. Thus, the aim of the present study was to evaluate the role of KLF4 in the proliferations of endo...

journal_title：Biochemical and biophysical research communications

authors： Zheng X,Li A,Zhao L,Zhou T,Shen Q,Cui Q,Qin X

更新日期：2013-08-09 00:00:00

abstract：:To examine the possible role of lipids as adhesion receptors for infection, Chlamydia trachomatis and Chlamydia pneumoniae were labeled with 125I and layered on thin-layer chromatograms (tlc) of separated lipids isolated from target cells, and bound bacteria were detected by autoradiography. Elementary bodies from bot...

journal_title：Biochemical and biophysical research communications

authors： Krivan HC,Nilsson B,Lingwood CA,Ryu H

更新日期：1991-03-29 00:00:00

abstract：:RNA extracts from the isthmus of laying hen oviduct contain truncated 5S RNA molecules that were found to be shorter at their 5' terminus as compared to native 5S RNA I and II. Moreover one of the truncated species differs from 5S RNA I by the absence of the 3' end nucleotide. The truncated forms increase of about 70%...

journal_title：Biochemical and biophysical research communications

authors： Keith G,Nys Y,Fix C,Heyman T

更新日期：1986-08-14 00:00:00

abstract：:We describe a new method for multi-wavelength immunoassays using surface plasmon-coupled emission (SPCE). This phenomenon is coupling of excited fluorophores with a nearby thin metal film, in our case silver, resulting in strongly directional emission into the underlying glass substrate. The angle at which the radiati...

journal_title：Biochemical and biophysical research communications

authors： Matveeva E,Malicka J,Gryczynski I,Gryczynski Z,Lakowicz JR

更新日期：2004-01-16 00:00:00

abstract：:The distribution and intracellular translocation of AFB1 in various subcellular fractions was investigated in isolated hepatocytes by pulse-chase experiments. After labeling the hepatocytes with [3H]-AFB1 (14.5 nM) for 15 min, the highest concentration of [3H]-AFB1 was found in the cytosolic fraction where 66% was bou...

journal_title：Biochemical and biophysical research communications

authors： Ch'ih JJ,Devlin TM

更新日期：1984-07-18 00:00:00

abstract：:Alzheimer's disease is a neurodegenerative disorder characterised by extracellular accumulation of the Abeta peptide, derived from the amyloid precursor protein (APP). The function of APP as a cell surface receptor was examined by ligand-mimicking using an antibody against the APP extracellular domain. Alterations in ...

journal_title：Biochemical and biophysical research communications

authors： Nilsson T,Malkiewicz K,Gabrielsson M,Folkesson R,Winblad B,Benedikz E

更新日期：2006-03-24 00:00:00

abstract：:Hepatocyte Growth Factor (HGF) was originally identified as hepatotrophic factor for liver regeneration. More recently, HGF was revealed to stimulate proliferation of various epithelial cells. At present study, we have investigated the mitogenic effect of HGF on gastric epithelial cells in the primary culture system. ...

journal_title：Biochemical and biophysical research communications

authors： Takahashi M,Ota S,Terano A,Yoshiura K,Matsumura M,Niwa Y,Kawabe T,Nakamura T,Omata M

更新日期：1993-03-15 00:00:00

abstract：:Thioredoxin (TRX) is one of major components of thiol reducing systems. To investigate the molecular mechanism of TRX function in the lung tissue, we screened a human lung epithelial cell cDNA library for TRX-binding protein by yeast two-hybrid systems. We isolated a plasmid containing C-propeptide region of human pro...

journal_title：Biochemical and biophysical research communications

authors： Matsumoto K,Masutani H,Nishiyama A,Hashimoto S,Gon Y,Horie T,Yodoi J

更新日期：2002-07-19 00:00:00

abstract：:Surgery and chemotherapy are the gold-standard treatments for ovarian cancer. The major cause of treatment failure in patients with ovarian cancer is tumoral heterogeneity and drug resistance. Paclitaxel (PTX) is one of the most commonly used first-line drugs for ovarian cancer chemotherapy. Unfortunately, the mechani...

journal_title：Biochemical and biophysical research communications

authors： Hong X,Li S,Li W,Xie M,Wei Z,Guo H,Wei W,Zhang S

更新日期：2019-01-15 00:00:00

abstract：:As part of an effort to identify genes potentially involved in the Down Syndrome pathogenesis, in this paper we report the identification and characterization of a new human gene (named SH3BGRL), which shows a high homology to the SH3BGR gene, previously mapped to the Down Syndrome region of chromosome 21. The SH3BGRL...

journal_title：Biochemical and biophysical research communications

authors： Egeo A,Mazzocco M,Arrigo P,Vidal-Taboada JM,Oliva R,Pirola B,Giglio S,Rasore-Quartino A,Scartezzini P

更新日期：1998-06-18 00:00:00

abstract：:WRKY transcription factors act as positive regulators in abiotic stress responses by activation of the cellular antioxidant systems. However, there are few reports on the response of WRKY genes to cadmium (Cd) stress. In this study, the role of maize ZmWRKY4 in regulating antioxidant enzymes in Cd stress was investiga...

journal_title：Biochemical and biophysical research communications

authors： Hong C,Cheng D,Zhang G,Zhu D,Chen Y,Tan M

更新日期：2017-01-22 00:00:00

abstract：:F(ab')2 fragments of anti-CD9 mAb aggregate platelets by a thromboxane-dependent pathway implicating CD9 as signal initiating molecule. We demonstrate that mAbs directed against CD9, but not against GPIIb/IIIa specifically immunoprecipitate, from detergent lysates of human platelets, proteins of 25 and 26 kDa which bi...

journal_title：Biochemical and biophysical research communications

authors： Seehafer JG,Shaw AR

更新日期：1991-08-30 00:00:00

abstract：:Endothelin (200 nM) evoked a rapid rise in [Ca2+]i which was then followed by a maintained elevation of [Ca2+]i. The initial transient can be explained by the release of stored Ca2+ whilst the maintained plateau is likely to be an influx of Ca2+ as it was partially inhibited by nifedipine (5 microM) and the remaining ...

journal_title：Biochemical and biophysical research communications

authors： Simpson AW,Ashley CC

更新日期：1989-09-29 00:00:00

abstract：:A series of C-terminal deleted analogs of human growth hormone-releasing factor (hGRF) with either an amidated or a free carboxylic acid C-terminus were synthesized by solid phase methodology. Their capacity to release growth hormone was tested on rat anterior pituitary cells in monolayer culture. A gradual decrease o...

journal_title：Biochemical and biophysical research communications

authors： Ling N,Baird A,Wehrenberg WB,Ueno N,Munegumi T,Brazeau P

更新日期：1984-09-17 00:00:00

abstract：:The 5'-untranslated sequence of tobacco mosaic virus RNA--the so called omega leader--is a well-known translational enhancer. The structure of the omega RNA has unusual features. Despite the absence of extensive secondary structure of the Watson-Crick type, the omega RNA possesses a stable compact conformation. The ce...

journal_title：Biochemical and biophysical research communications

authors： Agalarov SC,Sogorin EA,Shirokikh NE,Spirin AS

更新日期：2011-01-07 00:00:00

abstract：:Physically linked Dlx5 and Dlx6 paralogs are co-expressed in vertebrates and various combinations of null alleles in mice demonstrate not only functional redundancy between the paralogous factors but a similar quantitative contribution to craniofacial functions during development. While it is not possible to rule out ...

journal_title：Biochemical and biophysical research communications

authors： Quach A,MacKenzie RK,Bendall AJ

更新日期：2016-09-09 00:00:00

abstract：:To improve the expression of the genes transduced by retroviral vectors, we have constructed a U3-based retroviral vector and evaluated its effect on the expression of an insert from the internal promoter. The unique feature of the vector is that the transduced gene is inserted at the U3 region of the 3' long terminal...

journal_title：Biochemical and biophysical research communications

authors： Chen BF,Hsieh CL,Chen DS,Hwang LH

更新日期：1992-04-15 00:00:00

abstract：:Transient receptor potential canonical (TRPC) family contains a non-selective cation channel, and four TRPC subunits form a functional tetrameric channel. TRPC4/5 channels form not only the homotetrameric channel but also a heterotetrameric channel with TRPC1. We investigated the interaction domain required for TRPC1/...

journal_title：Biochemical and biophysical research communications

authors： Myeong J,Ko J,Hong C,Yang D,Lee KP,Jeon JH,So I

更新日期：2016-06-03 00:00:00