Effects of inhibiting transglutaminase during egg fertilization and development.

Abstract:

:Transglutaminase inhibitor (1,3,4,5-tetramethyl-2-[(2-oxopropyl)thio]imidazolium chloride or L-682777) affected the appearance of the fertilization envelope (FE) and subsequent development in Sphaerechinus granularis and Arbacia punctulata in a concentration-dependent manner. Abnormalities were first visible in forming FE's at the lowest concentration (0.001 mM) of the inhibitor used. The wrinkled appearance of FE's suggested that the treatment prevented the I-T transition, whereas the finding of numerous denuded cells and empty FE's indicated that the inhibitor acted by rendering the FE's very fragile. Cell division by the 2-cell stage was also affected by this active-site-directed transglutaminase inhibitor. With 0.05 mM of the inhibitor, about 50% of all cells were polynucleated. In view of earlier findings that other transglutaminase inhibitors can produce abnormalities with regard to FE wrinkling and deranged cell division, it can be suggested that different forms of transglutaminases might be involved at various stages in embryonic development.

authors

Cariello L,Zanetti L,Lorand L

doi

10.1006/bbrc.1994.2702

subject

Has Abstract

pub_date

1994-11-30 00:00:00

pages

565-9

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(84)72702-1

journal_volume

205

pub_type

杂志文章
  • Preparation of amyloid-like fibrils containing magnetic iron oxide nanoparticles: effect of protein aggregation on proton relaxivity.

    abstract::A method to prepare amyloid-like fibrils functionalized with magnetic nanoparticles has been developed. The amyloid-like fibrils are prepared in a two step procedure, where insulin and magnetic nanoparticles are mixed simply by grinding in the solid state, resulting in a water soluble hybrid material. When the hybrid ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2012.02.077

    authors: Andersson BV,Skoglund C,Uvdal K,Solin N

    更新日期:2012-03-23 00:00:00

  • Affinity of 22-oxa-1,25(OH)2D3 for 1,25-dihydroxyvitamin D receptor and its effects on the synthesis of osteocalcin in human osteosarcoma cells.

    abstract::A new 1,25-dihydroxyvitamin D3 analog, 22-oxa-1,25(OH)2D3, which may have pharmaceutical use, e.g., in the treatment of psoriasis, was studied using cultured MG-63 human osteosarcoma cells. We found that the new compound binds to 1,25-dihydroxyvitamin D receptors and regulates receptor mRNA levels like the natural lig...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(90)90377-y

    authors: Valaja T,Mahonen A,Pirskanen A,Mäenpää PH

    更新日期:1990-06-15 00:00:00

  • Minimal translation of the tmRNA tag-coding region is required for ribosome release.

    abstract::The trans-translation system in bacteria promotes recycling of stalled ribosomes and targets incomplete peptides for proteolysis. In Escherichia coli, loss of trans-translation function has little effect on growth under normal laboratory conditions. Among the subtle phenotypes of tmRNA-deficient mutants is the inabili...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2007.03.142

    authors: O'Connor M

    更新日期:2007-05-25 00:00:00

  • Inactivation of regulatory volume decrease in human peripheral blood lymphocytes by N-ethylmaleimide.

    abstract::The sulfhydryl group reagent N-ethylmaleimide was found to inhibit in a dose dependent manner regulatory volume decrease of human peripheral lymphocytes swollen in buffered hyposmotic NaCl media. In hyposmotic KCl media NEM treated lymphocytes prevented an additional secondary swelling seen in control lymphocytes. The...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(83)91554-1

    authors: Bauer J,Lauf PK

    更新日期:1983-11-30 00:00:00

  • A method for determining the intracellular distribution of enzymes in yeast provides no evidence for the association of hexokinase with mitochondria.

    abstract::A simple procedure based upon the principle discovered by Dürr et al. (Arch. Microbiol. (1975) 105, 319-327) was used to measure the intracellular distribution of enzymes in S. cerevisiae grown under both glucose repression and derepression. No substantial hexokinase activity was found to be associated with cellular o...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(86)90560-7

    authors: Kovác L,Nelson BD,Ernster L

    更新日期:1986-01-14 00:00:00

  • Functional studies of human GLUT5: effect of pH on substrate selection and an analysis of substrate interactions.

    abstract::The adsorption of D-fructose within the lumen of the human small intestine is thought to be mediated by the GLUT5 isoform of the human facilitative sugar transporter family. This isoform has been expressed in oocytes and shown to be capable of D-fructose transport. Some debate remains regarding the absolute substrate ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1997.7204

    authors: Kane S,Seatter MJ,Gould GW

    更新日期:1997-09-18 00:00:00

  • HeLa cells contain the atrial natriuretic peptide receptor with guanylate cyclase activity.

    abstract::Receptors for atrial natriuretic peptide (ANP) are heterogeneous: an approximately 140-kDa receptor exhibits ANP-stimulated guanylate cyclase activity whereas an approximately 65-kDa receptor is thought to act only as a clearance-storage protein. We have used photoaffinity labeling techniques to show that the human ce...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(89)91512-x

    authors: Watt VM,Yip CC

    更新日期:1989-10-31 00:00:00

  • HDC gene polymorphisms are associated with age at natural menopause in Caucasian women.

    abstract::Histidine decarboxylase gene (HDC) encodes histidine decarboxylase which is the crucial enzyme for the biosynthesis of histidine. Studies have shown that histamine is likely to be involved in the regulation of reproduction system. To find the possible correlation between HDC gene and AANM (age at natural menopause), w...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2006.08.008

    authors: Zhang F,Xiong DH,Wang W,Shen H,Xiao P,Yang F,Recker RR,Deng HW

    更新日期:2006-10-06 00:00:00

  • Reduction of Cripto-1 expression by a hammerhead-shaped RNA molecule results from inhibition of translation rather than mRNA cleavage.

    abstract::Cripto-1 (CR-1) is a transforming growth factor which has been associated with breast, colon, and pancreatic cancer. Overexpression of CR-1 in non-tumorigenic mouse mammary epithelial cells and fibroblasts results in an increase in anchorage-dependent and -independent growth in vitro. Reduction of CR-1 expression in h...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1998.8517

    authors: Kintner RL,Hosick HL

    更新日期:1998-04-28 00:00:00

  • Dolichol-sugar derivative synthesis in human breast cancer cell line (T47D). Effects of estrogens and antiestrogens.

    abstract::In the present paper we report evidence about the formation of polyprenyl-phosphate monosaccharides, their elongation products and the assembly of dolichyl-diphosphate-oligosaccharide to endogenous T47D clone 11 proteins upon incubation with [14C]glucose. The influence of estradiol and two nonesteroidal antiestrogens ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(85)90617-5

    authors: Santa Cruz AR,Medrano EE,Baldi A

    更新日期:1985-01-16 00:00:00

  • The carbohydrate structures of Trypanosoma brucei brucei MITat 1.6 variant surface glycoprotein. A re-investigation of the C-terminal glycan.

    abstract::We have studied the oligosaccharide chains of the variant surface glycoprotein (VSG) of Trypanosoma brucei brucei MITat 1.6. Glycopeptides were generated by Pronase digestion, purified by gel permeation and ion-exchange chromatography, and structurally characterized by 1H and 31P NMR spectroscopy in combination with c...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1993.2412

    authors: Strang AM,Allen AK,Holder AA,van Halbeek H

    更新日期:1993-11-15 00:00:00

  • The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice.

    abstract::Gastric inhibitory polypeptide (GIP) is released from the small intestine upon meal ingestion and increases insulin secretion from pancreatic β cells. Although the GIP receptor is known to be expressed in small intestine, the effects of GIP in small intestine are not fully understood. This study was designed to clarif...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2010.11.077

    authors: Ogawa E,Hosokawa M,Harada N,Yamane S,Hamasaki A,Toyoda K,Fujimoto S,Fujita Y,Fukuda K,Tsukiyama K,Yamada Y,Seino Y,Inagaki N

    更新日期:2011-01-07 00:00:00

  • Regulation of stretch-activated intracellular calcium transients by actin filaments.

    abstract::Stretch activation of cation-permeable channels may be an important proximal sensory mechanism in mechanotransduction. As actin filaments may mediate cellular responses to changes of the mechanical properties of the substrate and regulate stretch-induced calcium transients, we examined the role of actin filaments and ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1999.1057

    authors: Wu Z,Wong K,Glogauer M,Ellen RP,McCulloch CA

    更新日期:1999-08-02 00:00:00

  • The kinetics and magnesium requirements for the folding of antigenomic delta ribozymes.

    abstract::Using an oligonucleotide hybridization assay to gain insight into the folding of delta ribozymes, we demonstrate a correlation between their folding and catalytic behavior. Together with recent structural information on the crystal structure of self-cleaved genomic delta ribozyme, in which the L3 loop interacts with J...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.2000.2465

    authors: Ananvoranich S,Perreault JP

    更新日期:2000-04-13 00:00:00

  • The imidazoline RX871024 stimulates insulin secretion in pancreatic beta-cells from mice deficient in K(ATP) channel function.

    abstract::Effects of the imidazoline compound RX871024 on cytosolic free Ca(2+) concentration ([Ca(2+)]i) and insulin secretion in pancreatic beta-cells from SUR1 deficient mice have been studied. In beta-cells from wild-type mice RX871024 increased [Ca(2+)]i by blocking ATP-dependent K(+)-current (K(ATP)) and inducing membrane...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.2001.5068

    authors: Efanov AM,Høy M,Bränström R,Zaitsev SV,Magnuson MA,Efendic S,Gromada J,Berggren PO

    更新日期:2001-06-22 00:00:00

  • Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment.

    abstract::Voltage-gated potassium (K+) channel sub-family B member 1 (KCNB1, Kv2.1) is known to undergo oxidation-induced oligomerization during aging but whether this process affects brain's physiology was not known. Here, we used 10, 16 and 22 month-old transgenic mice overexpressing a KCNB1 variant that does not oligomerize ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2019.03.130

    authors: Yu W,Zhang H,Shin MR,Sesti F

    更新日期:2019-05-14 00:00:00

  • Differential expression of two forms of annexin 3 in human neutrophils and monocytes and along their differentiation.

    abstract::A variant of annexin 3 (AX3) of apparent mass 36 kD has been detected in human monocytes using a specific immune serum directed against the original 33-kD form of AX3 purified from human placenta. This protein is not a phosphorylated or a glycosylated form of the 33-kD AX3 and its expression increased along monocytic ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(92)90240-l

    authors: Le Cabec V,Russo-Marie F,Maridonneau-Parini I

    更新日期:1992-12-30 00:00:00

  • Modulation of in vitro kidney cell growth by hepatic transfer RNAs.

    abstract::The quiescent and proliferating status of the cell appears characterized by two different tRNA populations. The tRNA species changed both as relative percentage of total tRNA and in absolute concentration. The changes seem causally related to the proliferation status of the cell as tRNAs from proliferating hepatocytes...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1996.0665

    authors: Kanduc D

    更新日期:1996-04-25 00:00:00

  • Proinsulin maturation disorder is a contributor to the defect of subsequent conversion to insulin in β-cells.

    abstract::Disproportionate hyperproinsulinemia is an indicator of β-cell dysfunction in diabetes and the basis underlying this abnormality remains obscure. Recently, we have found proinsulin is an aggregation-prone molecule inherent with a low relative folding rate and maintains a homeostatic balance of natively and plentiful n...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2011.06.119

    authors: Wang J,Osei K

    更新日期:2011-07-22 00:00:00

  • The presence of free D-aspartic acid in rodents and man.

    abstract::Free D-aspartic acid is present in appreciable quantities in the brain and other tissues of rodents and in human blood. In the newborn rat, the highest concentration of D-aspartic acid was found in cerebral hemispheres, where, at 164 nmol/g (8.4% of the total aspartic acid), the level of D-aspartic acid exceeds that o...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/s0006-291x(86)80329-1

    authors: Dunlop DS,Neidle A,McHale D,Dunlop DM,Lajtha A

    更新日期:1986-11-26 00:00:00

  • Effects of recombinant human osteogenic protein-1 on the differentiation of osteoclast-like cells and bone resorption.

    abstract::Recombinant human OP-1 stimulated the formation of tartrate-resistant acid phosphatase (TRAP)-positive multinucleated cells (MNCs) significantly and in a dose-dependent manner in rat bone marrow cell culture. Newly formed MNCs either induced by hOP-1 alone or with 1,25(OH)2D3 were also positive for vitronectin recepto...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1995.1521

    authors: Hentunen TA,Lakkakorpi PT,Tuukkanen J,Lehenkari PP,Sampath TK,Väänänen HK

    更新日期:1995-04-17 00:00:00

  • PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.

    abstract::PES1 (also known as Pescadillo), a nucleolar protein, was involved in biogenesis of ribosomal RNA. Up-regulation of PES1 has been documented in some human cancers, indicating that PES1 may play some crucial roles in tumorigenesis. In our previous study, it was found that silencing of PES1 resulted in decreased prolife...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2012.12.145

    authors: Xie W,Qu L,Meng L,Liu C,Wu J,Shou C

    更新日期:2013-02-15 00:00:00

  • The isoforms of α-actin and myosin affect the Ca2+ regulation of the actin-myosin interaction in the heart.

    abstract::Myocardium of mammals contains a wide range of isoforms of proteins that provides contractile function of the heart. These are two isoforms of ventricular and two of atrial myosin, α- and β-tropomyosin, and two isoforms of α-actin: cardiac and skeletal. We believe that the difference in the amino acid sequence of α-ac...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2017.06.043

    authors: Shchepkin DV,Nikitina LV,Bershitsky SY,Kopylova GV

    更新日期:2017-08-19 00:00:00

  • Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.

    abstract::ABCG2 (also called MXR (3), BCRP (4), or ABCP (5) is a recently-identified ABC half-transporter, which causes multidrug resistance in cancer. Here we report that the expression of the ABCG2 protein in Sf9 insect cells resulted in a high-capacity, vanadate-sensitive ATPase activity in isolated membrane preparations. AB...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.2001.5130

    authors: Ozvegy C,Litman T,Szakács G,Nagy Z,Bates S,Váradi A,Sarkadi B

    更新日期:2001-07-06 00:00:00

  • Identification and physical organization of the gene cluster involved in the biosynthesis of Burkholderia cepacia complex exopolysaccharide.

    abstract::Bacteria belonging to the Burkholderia cepacia complex (BCC) are important opportunistic pathogens in patients with cystic fibrosis (CF). Since approximately 80% of the CF isolates examined produce exopolysaccharide (EPS), it was hypothesized that this EPS may play a role in the colonization and persistence of these b...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/j.bbrc.2003.10.118

    authors: Moreira LM,Videira PA,Sousa SA,Leitão JH,Cunha MV,Sá-Correia I

    更新日期:2003-12-12 00:00:00

  • Nuclear and cytoplasmic localization of the beta-amyloid peptide (1-43) in transfected 293 cells.

    abstract::Cultures of transformed human embryonic kidney 293 cells were transiently transfected with minigene constructs coding for the Abeta peptide (1-43). The Abeta minigene used in this study consisted of exons 16 and 17 of the amyloid precursor protein gene, including the 6000+ bp intronic region. Two of the constructs use...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1996.0469

    authors: Johnstone EM,Babbey LE,Stephenson D,Paul DC,Santerre RF,Clemens JA,Williams DC,Little SP

    更新日期:1996-03-27 00:00:00

  • Thromboxane A2 receptor linked with the Ca2+ pathway in rat colonic crypt cells.

    abstract::To clarify the presence of thromboxane A2 (TXA2) receptor in the colonic epithelium, we examined the effect of 9,11-epithio-11, 12-methano-thromboxane A2 (STA2), a stable analogue of TXA2, on intracellular free Ca2+ concentration ([Ca2+]i) of indo-1-loaded single cells in isolated rat colonic crypts by laser confocal ...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1999.0674

    authors: Ikari A,Sakai H,Sato T,Takeguchi N

    更新日期:1999-05-19 00:00:00

  • No evidence for mutations in a putative subunit of the beta-cell ATP-sensitive potassium channel (K-ATP channel) in Japanese NIDDM patients.

    abstract::The ATP-sensitive K channel (K-ATP channel) in pancreatic beta cells is believed to play a crucial role in glucose-stimulated insulin release. We investigated whether defects in the recently cloned gene for a putative subunit of this channel (KATP-2) could be a cause of diabetes in Japanese patients. The coding region...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1006/bbrc.1995.1915

    authors: Yasuda K,Sakura H,Mori Y,Iwamoto K,Shimokawa K,Kadowaki H,Hagura R,Akanuma Y,Adelman JP,Yazaki Y

    更新日期:1995-06-26 00:00:00

  • Microinjection of vesicular stomatitis virus ribonucleoprotein into animal cells yields infectious virus.

    abstract::Microinjection of purified transcriptionally active ribonucleoprotein (RNP) complex of vesicular stomatitis virus in vero cells resulted in the production and release of virus. Compared to the release of virus by cells treated with RNP in the presence of DEAE-dextran, the microinjection technique was highly efficient....

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/s0006-291x(83)80264-2

    authors: Thornton GB,Kopchick JJ,Stacey DW,Banerjee AK

    更新日期:1983-11-15 00:00:00

  • Synthesis and in vitro bioactivity of C-terminal deleted analogs of human growth hormone-releasing factor.

    abstract::A series of C-terminal deleted analogs of human growth hormone-releasing factor (hGRF) with either an amidated or a free carboxylic acid C-terminus were synthesized by solid phase methodology. Their capacity to release growth hormone was tested on rat anterior pituitary cells in monolayer culture. A gradual decrease o...

    journal_title:Biochemical and biophysical research communications

    pub_type: 杂志文章

    doi:10.1016/0006-291x(84)90309-7

    authors: Ling N,Baird A,Wehrenberg WB,Ueno N,Munegumi T,Brazeau P

    更新日期:1984-09-17 00:00:00