Chlamydia trachomatis and Chlamydia pneumoniae bind specifically to phosphatidylethanolamine in HeLa cells and to GalNAc beta 1-4Gal beta 1-4GLC sequences-found in asialo-GM1 and asial-GM2.

abstract：:Alpha-bulnesene is a sesquiterpenoid isolated from the water extract of Pogostemon cablin. It showed a potent and concentration-dependent inhibitory effect on platelet-activating factor (PAF) and arachidonic acid (AA) induced rabbit platelet aggregation. In a radioligand binding assay for the PAF receptor, alpha-bulne...

journal_title：Biochemical and biophysical research communications

authors： Hsu HC,Yang WC,Tsai WJ,Chen CC,Huang HY,Tsai YC

更新日期：2006-07-07 00:00:00

abstract：:Non-lethal hyperthermia is used clinically as adjuvant treatment to radiation, with mixed results. Denaturation of protein during hyperthermia treatment is expected to synergize with radiation damage to cause cell cycle arrest and apoptosis. Alternatively, hyperthermia is known to cause tissue level changes in blood f...

journal_title：Biochemical and biophysical research communications

authors： Kim YS,Lee TH,O'Neill BE

更新日期：2015-08-14 00:00:00

abstract：:Chikungunya is a severe disease that results from infection with the chikungunya virus (CHIKV), an arbovirus. Thus, we (1) explored a new approach to combining previously researched drugs that have shown the potential to inhibit CHIKV infection; and (2) demonstrated the antiviral effects of (-)-Epigallocatechin-3-gall...

journal_title：Biochemical and biophysical research communications

authors： Lu JW,Hsieh PS,Lin CC,Hu MK,Huang SM,Wang YM,Liang CY,Gong Z,Ho YJ

更新日期：2017-09-23 00:00:00

abstract：:Due to the structural and functional importance of tight turns, some methods have been proposed to predict gamma-turns, beta-turns, and alpha-turns in proteins. In the past, studies of pi-turns were made, but not a single prediction approach has been developed so far. It will be useful to develop a method for identify...

journal_title：Biochemical and biophysical research communications

authors： Wang Y,Xue ZD,Shi XH,Xu J

更新日期：2006-09-01 00:00:00

abstract：:Consumption of a single serving of tomatoes by healthy human volunteers was sufficient to alter levels of oxidative DNA base damage in white cell DNA within 24 h. Levels of the mutagenic oxidized purine base 8-hydroxyguanine decreased, especially in those subjects whose initial levels of this base were higher than the...

journal_title：Biochemical and biophysical research communications

authors： Rehman A,Bourne LC,Halliwell B,Rice-Evans CA

更新日期：1999-09-07 00:00:00

abstract：PURPOSE:Cancer stem cells (CSCs), also known as tumor-initiating cells, are involved in tumor progression, metastasis, and drug resistance. Hybrid liposomes (HLs) are nano-sized liposomal particles that can be easily prepared by ultrasonicating a mixture of vesicular and micellar molecules in buffer solutions. In this ...

journal_title：Biochemical and biophysical research communications

authors： Inamura K,Komizu Y,Yamakuchi M,Ishida S,Matsumoto Y,Matsushita T

更新日期：2019-01-29 00:00:00

abstract：:After allylisopropylacetamide-mediated "suicide" destruction of their prosthetic heme moieties, certain rat liver cytochrome P-450 isozymes can be effectively reconstituted by addition of exogenous hemin in vitro. We now report that two of these isozymes will equally accept mesohemin , a 2,4-diethyl heme-analog and re...

journal_title：Biochemical and biophysical research communications

authors： Bornheim LM,Correia MA,Smith KM

更新日期：1984-05-31 00:00:00

abstract：:Slo3 channels (mSlo3) primarily mediate mouse sperm K(+) currents and are essential for the capacitation-associated hyperpolarization (CAH). Whether Slo3 and/or Slo1, two Slo family K(+) channels are functionally expressed in human sperm is controversial. Our recent pharmacological studies of the human sperm CAH sugge...

journal_title：Biochemical and biophysical research communications

authors： Sánchez-Carranza O,Torres-Rodríguez P,Darszon A,Treviño CL,López-González I

更新日期：2015-10-23 00:00:00

abstract：:When the F1-ATPase from the thermophilic bacterium, PS3, was inactivated by 90% with 7-chloro-4-nitro[14C]benzofurazan ([14C]Nbf-Cl) at pH 7.3 and then gel-filtered, 1.25 mols of [14C]Nbf-O-Tyr and less than 0.1 mol of Nbf-N-Lys were formed per mol of enzyme. After adjusting the pH of the gel-filtered, modified enzyme...

journal_title：Biochemical and biophysical research communications

authors： Andrews WW,Yoshida M,Hill FC,Allison WS

更新日期：1984-09-28 00:00:00

abstract：:Lentil seedling amine oxidase catalyzes the oxidation of putrescine and in the presence of tetranitromethane gives rise to the formation of nitroform anion. The initial rate of substrate and enzyme-dependent nitroform production is linearly related to the functional active site content and is proportional to the tetra...

journal_title：Biochemical and biophysical research communications

authors： Medda R,Padiglia A,Pedersen JZ,Floris G

更新日期：1993-11-15 00:00:00

abstract：:The Frizzled-type cysteine-rich domain (CRD) is a binding motif for soluble-type glycoprotein WNTs, which play key roles in embryogenesis and carcinogenesis. Here, we have cloned and characterized a novel gene MFRP, encoding a type II transmembrane protein with CRD. In addition to CRD, two tandem-repeats containing th...

journal_title：Biochemical and biophysical research communications

authors： Katoh M

更新日期：2001-03-23 00:00:00

abstract：:The chaperonin containing t-complex polypeptide 1 (CCT) is a heterooligomeric molecular chaperone that assists in the folding of actin, tubulin, and other cytosolic proteins. We show here that degradation of CCT in mammalian cells is inhibited by a proteasome-specific inhibitor, lactacystin. When CCT synthesis was inh...

journal_title：Biochemical and biophysical research communications

authors： Yokota S,Kayano T,Ohta T,Kurimoto M,Yanagi H,Yura T,Kubota H

更新日期：2000-12-20 00:00:00

abstract：:This study investigated the effects of shear stress on gene expression of prostacyclin synthesis-related enzymes cyclooxygenases (COX-1 and COX-2), prostacyclin synthase (PGS), and thromboxane synthase (TXS) and their metabolites prostaglandin (PGI(2)) and thromboxane A(2) (TXA(2)) in endothelium of intact conduit ves...

journal_title：Biochemical and biophysical research communications

authors： Doroudi R,Gan LM,Selin Sjögren L,Jern S

更新日期：2000-03-05 00:00:00

abstract：:A common cause for pharmacogenetic alteration in drug response is genetic variation in encoded amino acid sequence. We have used the catecholamine and drug-metabolizing enzyme sulfotransferase (SULT)1A3 to create an artificial model system to study mechanisms-especially possible aggresome formation-by which genetic al...

journal_title：Biochemical and biophysical research communications

authors： Wang L,Yee VC,Weinshilboum RM

更新日期：2004-12-10 00:00:00

abstract：:Loss of CRY2 confers aggressive phenotypes to breast cancer. However, the mechanism of its downregulation and its prognostic value in breast cancer are still not clear. Our data mining in TCGA breast cancer cohort (TCGA-BRCA) showed that the luminal A subtype of breast cancer had the highest CRY2 expression, while the...

journal_title：Biochemical and biophysical research communications

authors： Liu L,Shen H,Wang Y

更新日期：2017-08-12 00:00:00

abstract：:Antitrypsin was resolved into two pools by ion-exchange chromatography. Pool 2 contained three anodal isoinhibitors and an N-terminal sequence identical with the one found by others. Pool 1 contained, in addition to the anodal ones two cathodal isoinhibitors as well. The sequencing data of Pool 1 indicate that the cat...

journal_title：Biochemical and biophysical research communications

authors： Hercz A

更新日期：1985-04-16 00:00:00

abstract：:Activins, TGF-beta superfamily members, have multiple functions in a variety of cells and tissues. Recently, additional activin beta subunit genes, betaC and betaE, have been identified. To explore the role of activin E, we created transgenic mice overexpressing human activin betaE subunit. There were pronounced diffe...

journal_title：Biochemical and biophysical research communications

authors： Hashimoto O,Ushiro Y,Sekiyama K,Yamaguchi O,Yoshioka K,Mutoh K,Hasegawa Y

更新日期：2006-03-10 00:00:00

abstract：:The proteins belonging to SWI2/SNF2 family of DNA dependent ATPases are important members of the chromatin remodeling complexes that are implicated in epigenetic control of gene expression. We have identified a human gene with a putative DNA binding domain, which belongs to the INO80 subfamily of SWI2/SNF2 proteins. H...

journal_title：Biochemical and biophysical research communications

authors： Bakshi R,Mehta AK,Sharma R,Maiti S,Pasha S,Brahmachari V

更新日期：2006-01-06 00:00:00

abstract：:Viral vectors displaying specific ligand binding moieties have raised an increasing interest in the area of targeted gene therapy. In this report, we describe baculovirus vectors displaying either a functional single chain antibody fragment (scFv) specific for the carcinoembryonic antigen (CEA) or the synthetic IgG bi...

journal_title：Biochemical and biophysical research communications

authors： Ojala K,Mottershead DG,Suokko A,Oker-Blom C

更新日期：2001-06-15 00:00:00

abstract：:Cytoplasmic polyadenylation element binding (CPEB) proteins are RNA-binding proteins involved in translational regulation of the specific target mRNAs and control function of various organs including brain, liver and hematopoietic system. However, the role of CPEB proteins during osteoclast differentiation remains unc...

journal_title：Biochemical and biophysical research communications

authors： Arasaki Y,Li M,Akiya T,Nozawa I,Ezura Y,Hayata T

更新日期：2020-08-06 00:00:00

abstract：:Dexamethasone (DEX) induces apoptosis in lymphocytes, while protecting some cancer cells from apoptosis, by a poorly understood mechanism. In this study, we examined the potential role of the forkhead transcription factor (FOXO3A) in DEX-induced apoptosis. Unphosphorylated FOXO3A, the active form of FOXO3A, can transl...

journal_title：Biochemical and biophysical research communications

authors： Ma J,Xie Y,Shi Y,Qin W,Zhao B,Jin Y

更新日期：2008-12-19 00:00:00

abstract：:Ceramide, the backbone of sphingolipids, has been reported to be involved in various cellular responses including apoptosis. We recently established and characterized a C2-ceramide-resistant HL-60 subline designated HL-CR. HL-CR cells were resistant to not only ceramide but also anti-cancer drugs including daunorubici...

journal_title：Biochemical and biophysical research communications

authors： Sawai H,Kawai S,Domae N

更新日期：2004-06-18 00:00:00

abstract：:The yeast transcriptional regulator Hap1 promotes both transcriptional activation and repression. Previous studies have shown that Hap1 binds to the promoter of its own gene and represses its transcription. In this report, we identified the DNA site that allows Hap1-binding with high affinity. This Hap1-binding site c...

journal_title：Biochemical and biophysical research communications

authors： Xin X,Lan C,Lee HC,Zhang L

更新日期：2007-10-12 00:00:00

abstract：:Tri-iodothyronine stimulates neurotensin secretion from rat hypothalami in vitro. Propylthiouracil treatment of rats is associated with a decrease in anterior pituitary neurotensin content, an increase in hypothalamic content and an impaired release of peptide from hypothalami in vitro. In addition neurotensin has a d...

journal_title：Biochemical and biophysical research communications

authors： Sheppard MC,Askew RD,Shennan KI,Franks S,Ramsden DB

更新日期：1983-05-31 00:00:00

abstract：:PICOT is a ubiquitous protein that has no functional redundant ortholog and is critical for mouse embryonic development. It is involved in the regulation of signal transduction in T lymphocytes and cardiac muscle, and in cellular iron metabolism and biogenesis of Fe/S proteins. However, very little is known about the ...

journal_title：Biochemical and biophysical research communications

authors： Pandya P,Pasvolsky R,Babichev Y,Braiman A,Witte S,Altman A,Isakov N

更新日期：2019-02-05 00:00:00

abstract：:In a number of cell lines responsive to basic fibroblast growth factor (bFGF), two major tyrosine phosphorylated proteins, of molecular weights around 120kDa and 90kDa, are precipitated along with the tyrosine phosphatase SHP2 from the lysates of stimulated cells. The docker protein Gab-1 represents at least part of t...

journal_title：Biochemical and biophysical research communications

authors： Ong SH,Lim YP,Low BC,Guy GR

更新日期：1997-09-08 00:00:00

abstract：:Epidemiological data have shown that stress and other psychological factors might influence cancer onset and progression. However, to date, the mechanisms are not well understood. In the present study, we used chronic exposure to a scream as a novel form of sound stress to explore the influence of the chronic stress b...

journal_title：Biochemical and biophysical research communications

authors： Hou N,Zhang X,Zhao L,Zhao X,Li Z,Song T,Huang C

更新日期：2013-10-04 00:00:00

abstract：BACKGROUND:Resistin is associated with insulin resistance, and determining its developmental and molecular mechanisms may help the development of novel treatments. MicroRNAs (miRNAs) are involved in many physiological and pathological processes as negative regulators. However, it remains unclear whether miRNAs play a r...

journal_title：Biochemical and biophysical research communications

authors： Wen F,Yang Y,Jin D,Sun J,Yu X,Yang Z

更新日期：2014-03-07 00:00:00

abstract：:GV1001, a synthetic peptide derived from human telomerase, has a range of diverse biological activities, including an antioxidant function. Here, we investigated the role of GV1001 in hepatitis C virus (HCV)-infected Huh7.5 (JFH-1) cells. We showed that GV1001 inhibited the production of ROS with decreased MAP kinase ...

journal_title：Biochemical and biophysical research communications

authors： Lee SA,Kim J,Sim J,Kim SG,Kook YH,Park CG,Kim HR,Kim BJ

更新日期：2016-02-26 00:00:00

abstract：:The homeodomain transcription factor Phox2b is one of the key determinants involved in the development of noradrenergic (NA) neurons in both the central nervous system (CNS) and the peripheral nervous system (PNS). Using yeast two-hybrid screening, we isolated a Phox2b interacting protein, Trim11, which belongs to TRI...

journal_title：Biochemical and biophysical research communications

authors： Hong SJ,Chae H,Lardaro T,Hong S,Kim KS

更新日期：2008-04-11 00:00:00