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Tomato consumption modulates oxidative DNA damage in humans.

Abstract：

:Consumption of a single serving of tomatoes by healthy human volunteers was sufficient to alter levels of oxidative DNA base damage in white cell DNA within 24 h. Levels of the mutagenic oxidized purine base 8-hydroxyguanine decreased, especially in those subjects whose initial levels of this base were higher than the mean. However, total DNA base damage remained unchanged since levels of 8-hydroxyadenine rose. The ability of tomato consumption to modulate oxidative DNA damage in the short term may indicate why daily consumption of fruits and vegetables is beneficial in decreasing cancer incidence.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Rehman A,Bourne LC,Halliwell B,Rice-Evans CA

doi

10.1006/bbrc.1999.1235

subject

Has Abstract

pub_date

1999-09-07 00:00:00

pages

828-31

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(99)91235-4

journal_volume

262

pub_type

杂志文章

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