Stk1-mediated phosphorylation stimulates the DNA-binding properties of the Staphylococcus aureus SpoVG transcriptional factor.

abstract：:Histamine H3 receptor (H3R), one of G protein-coupled receptors (GPCRs), has been known to regulate neurotransmitter release negatively in central and peripheral nervous systems. Recently, a variety of intracellular proteins have been identified to interact with carboxy (C)-termini of GPCRs, and control their intracel...

journal_title：Biochemical and biophysical research communications

authors： Maeda K,Haraguchi M,Kuramasu A,Sato T,Ariake K,Sakagami H,Kondo H,Yanai K,Fukunaga K,Yanagisawa T,Sukegawa J

更新日期：2008-05-02 00:00:00

abstract：:Human lymphoblastoid cell line (LCL) has been used as an in vitro cell model in genetic and pharmacogenomic studies, as well as a good model for studying gene expression regulatory machinery using integrated genomic analyses. In this study, we aimed to identify biological networks of LCL immortalization from transcrip...

journal_title：Biochemical and biophysical research communications

authors： Shim SM,Jung SY,Nam HY,Kim HR,Lee MH,Kim JW,Han BG,Jeon JP

更新日期：2013-11-15 00:00:00

abstract：:Osteoclastogenesis is dependent on distinct stimuli that prime and activate osteoclast differentiation. One cytokine needed to prime monocytes for osteoclastogenesis is TGF-beta, which enables and augments RANKL and TNF-alpha-induced osteoclast differentiation. However, the precise time-period during which this occurs...

journal_title：Biochemical and biophysical research communications

authors： Fox SW,Evans KE,Lovibond AC

更新日期：2008-02-01 00:00:00

abstract：:Dietary phosphate restriction produces an adaptive increase in renal tubular Na/Pi cotransport. A similar adaptation occurs during phosphate depletion in opossum kidney cells, a continuous line of cultured renal epithelial cells. We investigated the cellular changes associated with adaptation to phosphate depletion in...

journal_title：Biochemical and biophysical research communications

authors： Saxena S,Dansby L,Allon M

更新日期：1995-11-02 00:00:00

abstract：:The enzymatic mechanism of a small ribosome-inactivating protein, gamma-momorcharin, purified from the seeds of Momordica charantia, has been characterized. By SDS-polyacrylamide and electrospray ionization mass spectrometry, its molecular weight was measured to be 11,500 daltons which is much lower than other RIPs kn...

journal_title：Biochemical and biophysical research communications

authors： Pu Z,Lu BY,Liu WY,Jin SW

更新日期：1996-12-04 00:00:00

abstract：:Alveolar epithelial type I and type II cells (AEC I and II) are closely aligned in alveolar surface. There is much interest in the precise identification of AEC I and II in order to separate and evaluate functional and other properties of these two cells. This study aims to identify specific AEC I and AEC II cell mark...

journal_title：Biochemical and biophysical research communications

authors： Chen Z,Jin N,Narasaraju T,Chen J,McFarland LR,Scott M,Liu L

更新日期：2004-07-02 00:00:00

abstract：:Treatment of human peripheral blood monocytes with oxidized (oxLDL), minimally modified low-density lipoprotein (mmLDL) or lysophosphatidylcholine (LPC) for 24h was associated with macrophage-like differentiation, as assessed by morphology/CD14 expression. Suppression of these effects by staurosporin (STS) indicated t...

journal_title：Biochemical and biophysical research communications

authors： Weber C,Erl W,Weber PC

更新日期：1995-01-17 00:00:00

abstract：:Full activation of different T cell populations via the TcR/CD3 complex leads to transient expression of lymphokine mRNA and to transient and specific down-modulation of TcR, CD4, CD8 and p56lck mRNA (Multi-Receptor Complex or MRC mRNA). This transient down-modulation is due to both a decrease in transcription and sta...

journal_title：Biochemical and biophysical research communications

authors： Paillard F,Sterkers G,Vaquero C

更新日期：1992-07-31 00:00:00

abstract：:Dexamethasone (Dex) causes osteoblast cell injuries. In the present research, we tested the potential effect of SC79, a novel and specific Akt activator, against Dex in osteoblasts. In primary murine osteoblasts and osteoblastic MC3T3-E1 cells, pretreatment with SC79 significantly attenuated Dex-induced cell death. Fu...

journal_title：Biochemical and biophysical research communications

authors： Li ST,Chen NN,Qiao YB,Zhu WL,Ruan JW,Zhou XZ

更新日期：2016-10-07 00:00:00

abstract：:We have isolated calpromotin, a protein reported abundant in human red cells and shown to be of significance for KCl transport. We show that calpromotin is identical to a radical scavenger protein, thiol-specific antioxidant protein (TSA). Calpromotin is known to exist partially as a large complex of identical subunit...

journal_title：Biochemical and biophysical research communications

authors： Kristensen P,Rasmussen DE,Kristensen BI

更新日期：1999-08-19 00:00:00

abstract：:Previous genetic evidence led to the conclusion that proteinase B of yeast was not involved in the function of chitin synthetase 1 (Chs1), based on the demonstration of normal septum formation, cell division and chitin deposition in mutants devoid of the proteinase (Zubenko, G.S., Mitchell, A.P., and Jones, E.W. (1979...

journal_title：Biochemical and biophysical research communications

authors： Silverman SJ,Shaw JA,Cabib E

更新日期：1991-01-15 00:00:00

abstract：:A decline in intracellular nicotinamide adenine mononucleotide (NAD+) causes adipose tissue dysfunction. Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the rate-limiting step in the NAD+ biosynthesis pathway. However, the molecular mechanism that mediates regulation of NAMPT expression in adipocytes is yet t...

journal_title：Biochemical and biophysical research communications

authors： Mitani T,Watanabe S,Wada K,Fujii H,Nakamura S,Katayama S

更新日期：2020-02-12 00:00:00

abstract：:Recent research has revealed a role for Ambra1, an autophagy-related gene-related (ATG) protein, in the autophagic pro-survival response, and Ambra1 has been shown to regulate Beclin1 and Beclin1-dependent autophagy in embryonic stem cells and cancer cells. However, whether Ambra1 plays an important role in the autoph...

journal_title：Biochemical and biophysical research communications

authors： Shi C,Wu J,Fu M,Zhang B,Wang J,Yang X,Chi Y

更新日期：2014-09-26 00:00:00

abstract：:F(ab')2 fragments of anti-CD9 mAb aggregate platelets by a thromboxane-dependent pathway implicating CD9 as signal initiating molecule. We demonstrate that mAbs directed against CD9, but not against GPIIb/IIIa specifically immunoprecipitate, from detergent lysates of human platelets, proteins of 25 and 26 kDa which bi...

journal_title：Biochemical and biophysical research communications

authors： Seehafer JG,Shaw AR

更新日期：1991-08-30 00:00:00

abstract：:P53 is renowned as a cellular tumor suppressor poised to instigate remedial responses to various stress insults that threaten DNA integrity. P53 levels and activities are kept under tight regulation involving a complex network of activators and inhibitors, which determine the type and extent of p53 growth inhibitory s...

journal_title：Biochemical and biophysical research communications

authors： Levav-Cohen Y,Goldberg Z,Zuckerman V,Grossman T,Haupt S,Haupt Y

更新日期：2005-06-10 00:00:00

abstract：:Lafora disease, a progressive myoclonus epilepsy, is an autosomal recessive disease caused in approximately 80% of cases by mutation of the EPM2A gene, which encodes a dual specificity protein phosphatase called laforin. In addition to its phosphatase domain, laforin contains an N-terminal carbohydrate-binding domain ...

journal_title：Biochemical and biophysical research communications

authors： Wang W,Roach PJ

更新日期：2004-12-17 00:00:00

abstract：:Interactions between genes and environment play a critical role in the pathogenesis of type 2 diabetes. Low birth weight, due to genetic and environmental variables affecting fetal growth, is associated with increased susceptibility to the development of type 2 diabetes and metabolic disorders in adulthood. Clinical s...

journal_title：Biochemical and biophysical research communications

authors： Garg N,Thakur S,McMahan CA,Adamo ML

更新日期：2011-09-30 00:00:00

abstract：:We have characterized genomic structure and transcription of a murine odorant receptor (OR) gene, MOR23. This gene has two distinct transcriptional initiation regions, which are differentially utilized in the olfactory and testicular cells. We have found that the MOR23 gene has an intron within the 5'-untranslated reg...

journal_title：Biochemical and biophysical research communications

authors： Asai H,Kasai H,Matsuda Y,Yamazaki N,Nagawa F,Sakano H,Tsuboi A

更新日期：1996-04-16 00:00:00

abstract：:The cytoplasmic domain of the neural cell adhesion molecule (NCAM) contains multiple phosphorylation sites. We report here that in addition to serine and threonine residues a tyrosine of the NCAM180 isoform is phosphorylated as shown by phosphoamino acid analysis. Exchange of the only cytoplasmic tyrosine at position ...

journal_title：Biochemical and biophysical research communications

authors： Diestel S,Laurini C,Traub O,Schmitz B

更新日期：2004-09-10 00:00:00

abstract：:Protein L7 is associated with the large subunit of eukaryotic ribosomes that can act as a co-regulator of nuclear receptor-mediated transcription. In this study we show that L7 carries in addition to the known N-terminal nucleic acid-binding domain (NBD 1) a second one (NBD 2) which maps to the 50 C-terminal amino aci...

journal_title：Biochemical and biophysical research communications

authors： von Mikecz A,Neu E,Krawinkel U,Hemmerich P

更新日期：1999-05-19 00:00:00

abstract：:We report on a system to improve expression of mature c-type cytochromes in Escherichia coli. It is based on the use of plasmid pEC86 that expresses the E. coli cytochrome c maturation genes ccmABCDEFGH constitutively, whereby the production of both endogenous and foreign c-type cytochromes was increased substantially...

journal_title：Biochemical and biophysical research communications

authors： Arslan E,Schulz H,Zufferey R,Künzler P,Thöny-Meyer L

更新日期：1998-10-29 00:00:00

abstract：:Recent progress in human pluripotent stem cell (hPSC) and genome editing technologies has opened up new avenues for the investigation of human biology in health and disease as well as the development of therapeutic applications. Gene editing approaches with programmable nucleases have been successfully established in ...

journal_title：Biochemical and biophysical research communications

authors： Deleidi M,Yu C

更新日期：2016-05-06 00:00:00

abstract：:The bacterioferritin-associated ferredoxin (Bfd) of Escherichia coli is a 64-residue polypeptide encoded by the bfd gene located upstream of the gene (bfr) encoding the iron-storage haemoprotein, bacterioferritin. The Bfd sequence resembles those of the approximately 60-residue domains found in NifU proteins (required...

journal_title：Biochemical and biophysical research communications

authors： Quail MA,Jordan P,Grogan JM,Butt JN,Lutz M,Thomson AJ,Andrews SC,Guest JR

更新日期：1996-12-13 00:00:00

abstract：:Three amino-terminal-specific peptidic antibodies against cathepsin L were generated. These antibodies recognize in vitro processing products of procathepsin L in time-course-dependent fashion. Immunoblot analyses with these antibodies followed by immunoprecipitation with anti-cathepsin L antibody showed that the amin...

journal_title：Biochemical and biophysical research communications

authors： Ishidoh K,Saido TC,Kawashima S,Hirose M,Watanabe S,Sato N,Kominami E

更新日期：1998-11-09 00:00:00

abstract：:A subclone termed as HSG-S8 was previously isolated from human salivary adenocarcinoma cell line, HSG, and proliferated in a serum-free culture. When HSG-S8 and parental HSG cells were transplanted into nude mice i.m. or s.c., both cells reproducibly induced adenocarcinoma. Furthermore, injection of HSG-S8 consistentl...

journal_title：Biochemical and biophysical research communications

authors： Hatakeyama S,Ohara-Nemoto Y,Kyakumoto S,Satoh M

更新日期：1993-02-15 00:00:00

abstract：:Perforin, a potent pore-forming protein, plays an important role in killer lymphocyte-mediated cytolysis. The studies on perforin, although already extensive, have been hampered by the limited amount of perforin naturally available from killer lymphocytes. In the present study, a full-length mouse perforin was express...

journal_title：Biochemical and biophysical research communications

authors： Liu CC,Persechini PM,Young JD

更新日期：1994-05-30 00:00:00

abstract：:Glycogen phosphorylase (a or b) binds 125I-calmodulin in a Ca2+-dependent manner, in the 125I-calmodulin overlay technique. This binding is quantitatively identical to 125I-calmodulin binding to myosin light chain kinase. In an in vitro assay, calmodulin stimulates phosphorylase activity at limiting concentrations of ...

journal_title：Biochemical and biophysical research communications

authors： Slaughter GR,Means AR

更新日期：1985-01-16 00:00:00

abstract：:Diethanolamine (DEA), an alkanolamine used widely in industry, is hepatocarcinogenic in mice. The goal of this work was to determine whether DEA altered choline homeostasis in cultured cells, so as to ascertain whether the liver tumor response may be related to choline deficiency. CHO cells were cultured in Ham's F-12...

journal_title：Biochemical and biophysical research communications

authors： Lehman-McKeeman LD,Gamsky EA

更新日期：1999-09-07 00:00:00

abstract：:Thyroglobulin of very low iodine content has been prepared from a single non-toxic human goitre. The initial iodine content of the protein (0.038%) has been increased to levels of 0.16% and 0.85% by in vitro treatment with thyroid peroxidase and the resulting proteins studied with respect to their intrinsic fluorescen...

journal_title：Biochemical and biophysical research communications

authors： Zabel KM,Rawitch AB

更新日期：1984-05-31 00:00:00

abstract：:Rosiglitazone is a ligand of peroxisome proliferation-activated receptor gamma (PPARγ). However, it exerts biological activities and therapeutic effects through both PPARγ-dependent and independent mechanisms. In this study, we defined that rosiglitazone was also a ligand of retinoid X receptor alpha (RXRα) and displa...

journal_title：Biochemical and biophysical research communications

authors： Huang F,Li Y,Chen J,Zhang XK,Zhou H

更新日期：2020-09-10 00:00:00