The identification of novel protein, brain-derived integrating factor-1 (BDIF1), which interacts with astrocytic gap junctional protein.

abstract：:Ethanol's actions in brain have been suggested to be partially mediated by a mechanism involving the ethanol-induced activation of the endogenous opioid system. Opioid systems, which are closely linked with dopamine transmission, are thought to be affected by ethanol through alterations in the processing, release, and...

journal_title：Neuroscience research

authors： Méndez M,Leriche M,Carlos Calva J

更新日期：2003-10-01 00:00:00

abstract：:We have generated a transgenic mouse model in which astrocytes express an enhanced green fluorescent protein (EGFP) under the control of the mouse glial fibrillary acidic protein (GFAP) promoter. EGFP, which is characteristically found throughout the cell, was expressed in these animals even in astrocytic fine process...

journal_title：Neuroscience research

authors： Suzuki R,Watanabe J,Arata S,Funahashi H,Kikuyama S,Shioda S

更新日期：2003-12-01 00:00:00

abstract：:A mixture of peptidase inhibitors increased the magnitude of the saphenous nerve-evoked slow depolarization of a lumbar ventral root and prolonged the similarly evoked inhibition of monosynaptic reflex (MSR) in the isolated spinal cord of the newborn rat in the presence of naloxone. The saphenous nerve-evoked MSR inhi...

journal_title：Neuroscience research

authors： Yanagisawa M,Yoshioka K,Kurihara T,Saito K,Seno N,Suzuki H,Hosoki R,Otsuka M

更新日期：1992-12-01 00:00:00

abstract：:In the visual system, the afferent axons from the dorsal lateral geniculate nucleus (dLGN) to the primary visual cortex (V1) show significant activity-dependent plasticity in early postnatal life. To determine whether activity-dependent plasticity operates also in feedback projections from V1 to dLGN, we inactivated c...

journal_title：Neuroscience research

authors： Yoshida M,Satoh T,Nakamura KC,Kaneko T,Hata Y

更新日期：2009-05-01 00:00:00

abstract：:Type B neurons of the bullfrog sympathetic ganglia were examined to confirm the existence of axon collaterals and the distribution of synaptic contacts using the intracellular horseradish peroxidase (HRP) labeling method. The mean diameter of the perikarya was 60.8 (+/- 11.5 standard deviation; n = 36) X 43.8 (+/- 11....

journal_title：Neuroscience research

authors： Murata Y,Chiba T,Kumamoto E,Kuba K

更新日期：1989-10-01 00:00:00

abstract：:Using standard intracellular recording techniques 38 nonpyramidal cells or interneurons have been sampled in hippocampal slices of the rat. Among 38 physiologically identified interneurons, all 27 cells labeled with biocytin were morphologically demonstrated to be nonpyramidal and nongranule cells. The vast majority o...

journal_title：Neuroscience research

authors： Han ZS

更新日期：1994-02-01 00:00:00

abstract：:In rats with a unilateral 6-hydroxydopamine (6-OHDA)-induced lesion in the nigrostriatal fibers, methamphetamine (3 mg/kg, i.p.) induced Fos-like immunoreactivity (FLI), which was inhibited by pretreatment with N-methyl-D-aspartate antagonist MK-801 (1 mg/kg, i.p.), not only in the medial striatum contralateral to the...

journal_title：Neuroscience research

authors： Ishida Y,Todaka K,Kuwahara I,Nakane H,Ishizuka Y,Nishimori T,Mitsuyama Y

更新日期：1998-04-01 00:00:00

abstract：:Rhotekin, an effector of Rho, is highly expressed in the brain but its function(s) in neurons is almost unknown. In an attempt to define the properties of Rhotekin in neuronal cells, we focused on its interaction with polarity-related molecules. In the present study, we identified a PDZ protein, Lin-7B, as a binding p...

journal_title：Neuroscience research

authors： Sudo K,Ito H,Iwamoto I,Morishita R,Asano T,Nagata K

更新日期：2006-12-01 00:00:00

abstract：:Mature rat spinal cord cDNA libraries constructed in lambda gt10 and lambda ZAPII were screened with an oligonucleotide probe (39 mer), and 4 clones that possess DNA-inserts encoding a glycine receptor subunit were obtained. The cloned cDNAs were used to reconstruct the nucleotide sequence of the full-length open read...

journal_title：Neuroscience research

authors： Akagi H,Hirai K,Hishinuma F

更新日期：1991-06-01 00:00:00

abstract：:Mutations in the dynamin family GTPase OPA1 are reportedly the cause of autosomal dominant optic atrophy, the most frequently occurring form of hereditary optic neuropathy. But although the involvement of structural abnormalities of the enzyme in this neurodegenerative disease is clear, little is known about the cell ...

journal_title：Neuroscience research

authors： Misaka T,Murate M,Fujimoto K,Kubo Y

更新日期：2006-06-01 00:00:00

abstract：:Zinc is one of trace elements that play essential roles in several cell functions, and is unquestionably important to the normal health and function of the central nervous system. Growing evidence suggests that Zn(2+) can become a pathogenic agent in certain neurological disease states, such as ischemia, seizures, and...

journal_title：Neuroscience research

authors： Tian Y,Yang Z,Zhang T

更新日期：2010-11-01 00:00:00

abstract：:In an attempt to test the possibility that sino-aortic baroreceptors may mediate the previously reported stress response in hypothalamic magnocellular neurosecretory cell activity in rats, effects of deafferentation of sino-aortic baroreceptors on plasma levels of vasopressin and oxytocin after fear-related emotional ...

journal_title：Neuroscience research

authors： Onaka T,Yagi K

更新日期：1992-04-01 00:00:00

abstract：:Single units of the adrenal sympathetic nerve (n = 46) were dissected and characterized with respect to tonic discharge and response to cutaneous and baroreceptor stimulation. The frequency of tonic discharge averaged 1.6 Hz and cardiovascular rhythmic modulation was observed in 53% of the units. The stimuli employed ...

journal_title：Neuroscience research

authors： Ito K,Sato A,Shimamura K,Swenson RS

更新日期：1984-04-01 00:00:00

abstract：:RNA editing provides a post-transcriptional mechanism to increase structural heterogeneity of gene products. Recently, the alpha3 subunit of the GABAA receptors has been shown to undergo RNA editing. As a result, a highly conserved isoleucine residue in the third transmembrane domain is replaced with a methionine. To ...

journal_title：Neuroscience research

authors： Nimmich ML,Heidelberg LS,Fisher JL

更新日期：2009-04-01 00:00:00

abstract：:We previously demonstrated that metabotropic glutamate receptor-subtype 1 knockout [mGluR1 (-/-)] mice showed ataxic gait, deficient long-term depression and impaired synapse elimination and these phenotypes were rescued by introduction of an mGluR1 transgene with Purkinje cell-specific promoter (mGluR1-rescue mice). ...

journal_title：Neuroscience research

authors： Nakao H,Nakao K,Kano M,Aiba A

更新日期：2007-04-01 00:00:00

abstract：:Although sleep is strongly implicated in memory consolidation, the molecular basis for the role of sleep in memory is not known. It has been established that the consolidation of hippocampus-dependent memory depends on the activation of the Erk1,2 MAP kinase (MAPK) pathway which activates de novo CRE-mediated transcri...

journal_title：Neuroscience research

authors： Xia Z,Storm D

更新日期：2017-05-01 00:00:00

abstract：:The aim of the present study was to investigate whether increased concentrations of lactic acid and potassium chloride (KCl) in contralateral muscles can influence the sensitivity of primary and secondary muscle spindle afferents (MSAs) from ipsilateral extensor and flexor muscles. The experiments were performed on 7 ...

journal_title：Neuroscience research

authors： Djupsjöbacka M,Johansson H,Bergenheim M,Sjölander P

更新日期：1995-02-01 00:00:00

abstract：:We previously reported that the gamma gamma-isozyme of enolase, NSE), one of the glycolytic enzymes, promoted the survival of embryonic rat neocortical neurons in culture, but alpha alpha-isozyme (non-neuronal enolase) had no effect. In the present study, the neurotrophic effects of NSE on cultured mesencephalic and s...

journal_title：Neuroscience research

authors： Hattori T,Takei N,Mizuno Y,Kato K,Kohsaka S

更新日期：1995-01-01 00:00:00

abstract：:Recently, we reported a profound depletion of cardiac sympathetic nerve fibers in Parkinson's disease (PD). This cardiac sympathetic denervation is a characteristic hallmark of PD. Cardiac sympathetic dysfunction was also observed in 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP)-treated mice, a model of PD. Al...

journal_title：Neuroscience research

authors： Amino T,Uchihara T,Tsunekawa H,Takahata K,Shimazu S,Mizusawa H,Orimo S

更新日期：2008-03-01 00:00:00

abstract：:Bacterial lipopolysaccharide (LPS) is a major component of the cell wall of gram negative bacteria contributing to the pathogenesis of bacterial infection, in particular in those diseases affecting central nervous system and reproductive tissues. The present work is an attempt to study the regulation of steroidogenic ...

journal_title：Neuroscience research

authors： Sadasivam M,Ramatchandirin B,Ayyanar A,Prahalathan C

更新日期：2014-06-01 00:00:00

abstract：:Pathological gambling (PG) is a non-substance based addiction that shares many behavioral and neural features with substance based addictions. However, in PG behavioral and neural changes are unlikely to be confounded by effects of acute or chronic drug exposure. Changes in reward based decision-making in particular i...

journal_title：Neuroscience research

authors： Wiehler A,Peters J

更新日期：2015-01-01 00:00:00

abstract：:A disynaptic projection from the spinal cord to the striatum was observed in the rat light and electron microscopically. An anterograde tracer, wheat germ agglutinin conjugated to horseradish peroxidase was injected into the ventral gray matter of the upper cervical spinal cord, and a retrograde tracer, biotinylated d...

journal_title：Neuroscience research

authors： Nakamura Y,Otake K,Tokuno H

更新日期：2006-09-01 00:00:00

abstract：:Light-induced changes in the input resistance (Rin) of external, luminosity (i.e. H1) type horizontal cell (HC) perikarya were studied by the bridge-balance method in light-adapted and dark-adapted retinae of carp. Changes in input resistance (delta Rin) induced by short-(460 nm) and long-wavelength (674 nm) flashes, ...

journal_title：Neuroscience research

authors： Furukawa T,Yamada M,Petruv R,Djamgoz MB,Yasui S

更新日期：1997-01-01 00:00:00

abstract：:Action potentials, when arriving at presynaptic terminals, elicit Ca(2+) influx through voltage-gated Ca(2+) channels. Intracellular [Ca(2+)] elevation around the channels subsequently triggers synaptic vesicle exocytosis and also induces various protein reactions that regulate vesicle endocytosis and recycling to pro...

journal_title：Neuroscience research

authors： Yamashita T

更新日期：2012-05-01 00:00:00

abstract：:Striatonigral axons co-release GABA and substance P (SP) at their target sites, but little is known about the action of SP at nigral level. Therefore, we studied immunohistochemically the cellular and subcellular localization of SP and its high affinity receptors neurokinin-1 (NK-1R) and neurokinin-3 (NK-3R) at nigral...

journal_title：Neuroscience research

authors： Lévesque M,Wallman MJ,Parent R,Sík A,Parent A

更新日期：2007-03-01 00:00:00

abstract：:This paper describes for the first time the phenomenon of spatio-temporal mapping of interchannel temporal coincidences of rapid transition processes (RTPs) in multiple EEG frequencies. It is suggested that RTPs in multiple EEG frequencies found in different EEG channels could reflect the process of switching between ...

journal_title：Neuroscience research

authors： Fingelkurts AA,Fingelkurts AA

更新日期：2010-11-01 00:00:00

abstract：:A time production test was performed in seven normal females and seven females with premenstrual syndrome (PMS). We used a time production test for six time intervals (6, 12, 24, 36, 48, 60 s). Time production tests were performed at 08:00, 14:00 and 20:00 h in the follicular, early luteal and late luteal phases (LLP)...

journal_title：Neuroscience research

authors： Morofushi M,Shinohara K,Kimura F

更新日期：2001-12-01 00:00:00

abstract：:Using immunohistochemistry and retrograde transport techniques, this study demonstrates that serotonin (5-HT) cells in the dorsal tegmental gray of the pons at rostrocaudal from P1 to P6 levels are sources of bilateral serotonergic projections to the gigantocellular tegmental field of the medial pontine and medullary ...

journal_title：Neuroscience research

authors： Kobayashi Y,Matsuyama K,Mori S

更新日期：1994-07-01 00:00:00

abstract：:Event-related potentials (ERPs) during an auditory discrimination task were recorded both on the surface and at a depth of the auditory cortex in rats. Ten-kilohertz rare and 5-kHz frequent tones were used with the probabilities of 0.2 and 0.8. Lever pressing within 2 s, following the onset of the rare tone, was rewar...

journal_title：Neuroscience research

authors： Iwanami A,Shinba T,Sumi M,Ozawa N,Yamamoto K

更新日期：1994-11-01 00:00:00

abstract：:GABAergic neurons in the hippocampus proper are greatly diverse in their morphological and physiological features. In the present study we examined whether or not they are also diverse regarding the density of GABAergic input on their somata. GABAergic neurons were immunocytochemically identified with antibodies again...

journal_title：Neuroscience research

authors： Fukuda T,Aika Y,Heizmann CW,Kosaka T

更新日期：1996-10-01 00:00:00