Abstract：
:In an attempt to test the possibility that sino-aortic baroreceptors may mediate the previously reported stress response in hypothalamic magnocellular neurosecretory cell activity in rats, effects of deafferentation of sino-aortic baroreceptors on plasma levels of vasopressin and oxytocin after fear-related emotional stress were studied in male rats 28-33 days after the surgery. An alpha 1-adrenergic receptor agonist, phenylephrine (1 mg/kg) injected i.p. under anesthesia increased arterial blood pressure in the rats that had received surgical operation of sino-aortic denervation (SAD) and in the rats of sham-operation control (SHAM). Reflex bradycardia after phenylephrine occurred in the SHAM but not in the SAD group. These results indicate that afferent signals originating from sino-aortic baroreceptors were effectively blocked by the SAD surgery. In the similarly prepared SAD group, plasma level of vasopressin was decreased and plasma level of oxytocin was increased significantly to the same extent as in the SHAM group after low-frequency shocks (0.05 Hz, 5 min) or environmental cue signals previously paired with shocks. It is therefore suggested that afferent neural signals originating from sino-aortic baroreceptors are not primarily involved in the suppressive vasopressin or the facilitatory oxytocin response to fear-related emotional stress in rats.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Onaka T,Yagi Kdoi
10.1016/0168-0102(92)90059-lsubject
Has Abstractpub_date
1992-04-01 00:00:00pages
199-206issue
3eissn
0168-0102issn
1872-8111pii
0168-0102(92)90059-Ljournal_volume
13pub_type
杂志文章abstract：:The aim of this study was to investigate the differences between children and adults in recognizing facial expressions of simple line drawings of "Chernoff's face". First, the angles of the eyebrows and mouth of Chernoff's face were changed in a stepwise way with a personal computer, and the emotional response of the ...
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更新日期：2018-04-01 00:00:00
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更新日期：1992-02-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：1993-03-01 00:00:00
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journal_title：Neuroscience research
pub_type： 杂志文章
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更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Global field synchronization (GFS) has recently been introduced to measure functional synchronization in frequency-domain EEG data. This study explored GFS values and its clinical significance in patients with Alzheimer's disease (AD). METHOD:EEGs were recorded from 22 AD patients and 23 age-matched healthy...
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pub_type： 杂志文章
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