Novel insights into the pathobiology of the vascular access - do they translate into improved care?

abstract：:The number of geriatric patients on dialysis is increasing. This is due to demographic factors, a wider acceptance of elderly patients on dialysis, and an earlier start of dialysis in this patient group. Recent studies have questioned the effect of dialysis on quality of life in elderly patients with severe comorbidit...

journal_title：Blood purification

authors： Kooman JP,Cornelis T,van der Sande FM,Leunissen KM

更新日期：2012-01-01 00:00:00

abstract：:Kidney transplantation (KT) is considered an optimal treatment strategy for end-stage renal disease. But human leukocyte antigen-sensitized, ABO-incompatible and antibody-mediated rejection might be the alarming hurdles in KT. Therapeutic plasma exchange is the mainstay of the antibody reduction therapy for reducing a...

journal_title：Blood purification

authors： Xie P,Tao M,Peng K,Zhao H,Zhang K,Sheng Y,Ankawi G,Ronco C

更新日期：2019-01-01 00:00:00

abstract：:Pathophysiological aspects of plasma volume preservation and cardiovascular reactivity are reviewed, comparing combined ultrafiltration-hemodialysis with isolated ultrafiltration and hemofiltration. The role of different factors in the disparity in cardiovascular reactivity between these treatments is discussed. ...

journal_title：Blood purification

authors： Hendrikus W,van Kuijk M,Leunissen KM

更新日期：1996-01-01 00:00:00

abstract：:Guidelines have been developed in nephrology and medicine developed to assist practitioners and patients in making decisions about healthcare for specific clinical circumstances. There has been a proliferation of guidelines over the last decade in all areas of medicine, including nephrology. Many of the nephrology gui...

journal_title：Blood purification

authors： Levin A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Frequent hemodialysis (HD) may be associated with an increased risk of vascular access complications. Studies addressing vascular access outcomes in frequent HD show conflicting results. METHODS:We searched Medline for trials looking at vascular access outcomes in frequent HD. RESULTS:Nineteen studies met ...

journal_title：Blood purification

authors： Cornelis T,Usvyat LA,Tordoir JH,Wang Y,Wong M,Leunissen KM,van der Sande FM,Kotanko P,Kooman JP

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Hemoadsorption may improve outcomes for sepsis by removing circulating cytokines. We tested a new sorbent used for hemoadsorption. METHODS:CTR sorbent beads were filled into columns of three sizes: CTR0.5 (0.5 ml), CTR1 (1.0 ml) and CTR2 (2.0 ml) and tested using IL-6 capture in vitro. Next, rats were ...

journal_title：Blood purification

authors： Zhang J,Peng Z,Maberry D,Volpe J,Kimmel JD,Federspiel WJ,Kellum JA

更新日期：2015-01-01 00:00:00

abstract：:There is a wide variability in the utilization of peritoneal dialysis throughout Europe that cannot be explained by differences in medical factors alone. Over the last years, the utilization of peritoneal dialysis has even changed in individual countries. The main factors of this variation are not medical, but rather ...

journal_title：Blood purification

authors： Lameire N,Peeters P,Vanholder R,Van Biesen W

更新日期：2006-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is a common complication in pediatric and neonatal intensive care units (ICU). Renal replacement therapy (RRT) is frequently needed in children in whom supportive therapy is not enough to satisfy their metabolic demands or to be able to provide adequate nutrition. The decision to begin dialys...

journal_title：Blood purification

authors： Bonilla-Félix M

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:This study was aimed at evaluating the efficacy and safety of regional citrate anticoagulation (RCA) versus no-anticoagulation continuous venovenous hemofiltration (CVVH) in acute severe hypernatremia patients with increased bleeding risk. MATERIALS AND METHODS:Acute severe hypernatremia patients with high ble...

journal_title：Blood purification

authors： Zhao L,Ma F,Yu Y,Li Y,Wang Y,He L,Zhou M,Tian X,Jing R,Li L,Li L,Huang C,Bai M,Sun S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND AIM:Elevated low-density lipoprotein cholesterol and/or lipoprotein(a) are established risk factors for cardiovascular disease (CVD). Management of hypercholesterolemia consists of drug therapies, including statins and proprotein convertase subtilisin/kexin type 9 inhibitors. In patients with familial hy...

journal_title：Blood purification

authors： Raina R,Young C,Krishnappa V,Chanchlani R

更新日期：2019-01-01 00:00:00

abstract：:Conventional treatment of acute and chronic renal diseases has focused on solute removal. Novel strategies aim to treat the multifactorial disease states of acute kidney injury and chronic kidney disease by mitigating inflammation. Cell-based technologies for the treatment of kidney dysfunction fall under two broad ca...

journal_title：Blood purification

authors： Pino CJ,Yevzlin AS,Tumlin J,Humes HD

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Abnormalities in fluid status in hemodialysis (HD) patients are highly prevalent and are related to adverse outcomes. SUMMARY:The inherent discontinuity of the HD procedure in combination with an often compromised cardiovascular response is a major contributor to this phenomenon. In addition, systemic infla...

journal_title：Blood purification

authors： Kooman JP,van der Sande FM

更新日期：2019-01-01 00:00:00

abstract：:Heart failure results in significant morbidity and mortality in the United States. Chronic heart failure is often complicated by renal insufficiency. Further, acute decompensated heart failure is often complicated by worsening renal function or the development of diuretic resistance. Heart failure complicated by renal...

journal_title：Blood purification

authors： Kociol R,Rogers J,Shaw A

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Removal of protein-bound uremic toxins by dialysis therapy is limited. The effect of oral adsorbent AST-120 in chronic dialysis patients has rarely been investigated. METHODS:AST-120 was administered 6.0 g/day for 3 months in 69 chronic dialysis patients. The blood concentrations of indoxyl sulfate, p-creso...

journal_title：Blood purification

authors： Lee CT,Hsu CY,Tain YL,Ng HY,Cheng BC,Yang CC,Wu CH,Chiou TT,Lee YT,Liao SC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:To determine adsorption and transmembrane clearances (CLTM) of rezafungin, a novel long-acting echinocandin, in continuous venovenous hemofiltration (CVVH). METHODS:A validated ex vivo bovine blood CVVH model using polysulfone and AN69 hemodiafilters was used to evaluate urea and rezafungin CLTM at 3 d...

journal_title：Blood purification

authors： Jang SM,Hough G,Mueller BA

更新日期：2018-01-01 00:00:00

abstract：:Several strategies have been proposed to increase dialysis efficiency in order to reduce dialysis treatment time. Paired filtration dialysis (two-chamber technique) is a new technique combining the advantages of highly permeable membranes and convective transport with the high depurative efficacy of diffusion. The sys...

journal_title：Blood purification

authors： Ronco C,Feriani M,Brendolan A,Chiaramonte S,Milan M,Dell'Aquila R,Scabardi M,Bragantini L,Conz P,La Greca G

更新日期：1990-01-01 00:00:00

abstract：:In 5 uremic patients the role of opioid peptides in dialysis-induced hypotension was investigated through the administration of naloxone. An intravenous bolus injection of 1 mg of naloxone was administered immediately before starting a routine hemodialysis session and was repeated when the patients' systolic arterial ...

journal_title：Blood purification

authors： Sturani A,Degli Esposti E,Chiarini C,Spongano M,Santoro A,Zucchelli P

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND/AIMS:The objective of this study is to evaluate the relation between sclerostin, arterial stiffness, and cardiovascular events (CVE) in hemodialysis patients (HD). METHODS:Sclerostin level and carotid-femoral pulse wave velocity (PWV) in 97 HD patients and sclerostin level in 40 controls were measured. RES...

journal_title：Blood purification

authors： Kundakci Gelir G,Sengul S,Nergizoglu G,Ertürk S,Duman N,Kutlay S

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Plastic cannulas have been used to cannulate arteriovenous fistulas (AVFs) for hemodialysis (HD) in Japan for many years. However, the effect of early cannulation with plastic cannulas on AVF patency is not known. OBJECTIVE:We analyzed the relationship between first cannulation time (FCT) and patency rate...

journal_title：Blood purification

authors： Shi K,Jiang H,Wakabayashi M

更新日期：2020-01-01 00:00:00

abstract：:In this work we investigated the acute effects of hemodiafiltration with endogenous reinfusion (HFR therapy) on the removal of free immunoglobulin light chains (FIgLCs), which may be considered members of the family of uremic toxins. In two groups of patients - group 1 (polyclonal FIgLCs production) and group 2 (monoc...

journal_title：Blood purification

authors： Testa A,Dejoie T,Lecarrer D,Wratten M,Sereni L,Renaux JL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Dialysis membrane has been implicated in selenium (Se) deficiency in hemodialysis (HD). Intradialytic Se removal into dialysate through different membranes was investigated. METHODS:We studied 19 patients on standard HD with low-flux polysulfone membrane (group A), 10 patients on standard HD with ethyl...

journal_title：Blood purification

authors： Sonikian M,Dona A,Skarakis J,Trompouki S,Miha T,Karatzas I,Spiliopoulou C

更新日期：2016-01-01 00:00:00

abstract：AIMS:To assess whether kidney transplantation improves sleep-related breathing disorders associated with hemodialysis. METHODS:A prospective study was carried out using full-night polysomnography. Nine hemodialysis patients (7 men and 2 women, aged 42 +/- 16.2 years, BMI 26 +/- 3.7) who later received a successful kid...

journal_title：Blood purification

authors： Jurado-Gámez B,Martin-Malo A,Rodriguez-Benot A,Muñoz-Cabrera L,Cosano Povedano A,Aljama P

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Standard low-flux haemodialysis (HD) is not very efficacious, and patient morbidity and mortality rates are still very high. According to the initial study design, the MPO study reported that high-flux HD (hf-HD) showed a significant 37% relative risk reduction of mortality in patients with serum albumin ≤4 ...

journal_title：Blood purification

authors： Locatelli F,Violo L,Longhi S,Del Vecchio L

更新日期：2015-01-01 00:00:00

abstract：:In previous reports of the Frequent Hemodialysis Network trials, frequent hemodialysis (HD) reduced extracellular fluid (ECF) and left ventricular mass (LVM), with more pronounced effects observed among patients with low urine volume (UVol). We analyzed the effect of frequent HD on interdialytic weight gain (IDWG) and...

journal_title：Blood purification

authors： Raimann JG,Chan CT,Daugirdas JT,Depner T,Gotch FA,Greene T,Kaysen GA,Kliger AS,Kotanko P,Larive B,Lindsay R,Rocco MV,Chertow GM,Levin NW,Frequent Hemodialysis Network (FHN) Trial Group.

更新日期：2016-01-01 00:00:00

abstract：:The evidence concerning online hemodiafiltration (HDF) includes the following: (1) the increase of removal of uremic toxin, (2) the prevention of dialysis rerated hypotension, (3) the recovery of survival, and (4) the recovery of dialysis related uncertain symptoms. Although clinical evidence has been noted, the hypot...

journal_title：Blood purification

authors： Kawanishi H

更新日期：2018-01-01 00:00:00

abstract：UNLABELLED:Hyperhomocysteinemia (HH), a known risk factor for vascular diseases, is a frequent condition in hemodialysis (HD) patients. HH induces an oxidant stress to the vascular endothelium, causing a failure of vasodilation and an impairment of the antithrombotic properties. Vitamins B(6), B(12) and folic acid are ...

journal_title：Blood purification

authors： Biasioli S,Schiavon R

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:N-Terminal pro-brain natriuretic peptide (NT-proBNP) is a predictor of cardiac events and death in the general population and in chronic kidney disease. There is limited information on how natriuretic peptides vary in dialysis patients. The aim of this study was to analyze NT-proBNP variability, factors...

journal_title：Blood purification

authors： Snaedal S,Qureshi AR,Carrero JJ,Heimbürger O,Stenvinkel P,Bárány P

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The present study aimed to determine the variables that are associated with a longer dialysis recovery time (DRT) and to define the relationship that exists between DRT and the ultrafiltration rate (UFR) in prevalent chronic hemodialysis (CHD) patients. METHODS:We studied 210 prevalent CHD of 5 hemodialys...

journal_title：Blood purification

authors： Bossola M,Di Stasio E,Monteburini T,Parodi E,Ippoliti F,Cenerelli S,Santarelli S,Nebiolo PE,Sirolli V,Bonomini M,Antocicco M,Zuccalà G,Laudisio A

更新日期：2019-01-01 00:00:00

abstract：:Endothelial dysfunction of the optic microcirculation is considered to be the main pathogenetic mechanism in nonarteritic ischemic optic neuropathy. The aim of the present work was to assess whether a clinical improvement is correlated with a reduction in the endothelial activation markers by means of LDL apheresis (L...

journal_title：Blood purification

authors： Ramunni A,Ranieri G,Giancipoli G,Guerriero S,Ria R,Saliani MT,Sborgia L,Ranieri P,Coratelli P

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Glucose absorbed from conventional peritoneal dialysis (PD) solutions contributes to unfavorable metabolic effects. Its replacement with a glucose-free osmotic agent such as icodextrin (ID) or amino acids (AA) may have some benefit on glucose and lipid metabolism. METHODS:Serum lipids, insulin sensitivity a...

journal_title：Blood purification

authors： Martikainen T,Teppo AM,Gronhagen-Riska C,Ekstrand A

更新日期：2005-01-01 00:00:00