当前位置： SCI文献检索 > BLOOD PURIFICATION期刊下所有文献 > Recovery Time after Hemodialysis Is Inversely Associated with the Ultrafiltration Rate.

Recovery Time after Hemodialysis Is Inversely Associated with the Ultrafiltration Rate.

Abstract：

INTRODUCTION:The present study aimed to determine the variables that are associated with a longer dialysis recovery time (DRT) and to define the relationship that exists between DRT and the ultrafiltration rate (UFR) in prevalent chronic hemodialysis (CHD) patients. METHODS:We studied 210 prevalent CHD of 5 hemodialysis units in Central Italy. Patients were invited to answer to the question: "How long does it take you to recover from a dialysis session?" Answers to this question were subsequently converted into minutes. Demographic, clinical and laboratory parameters were recorded for each patient as well as the UFR (mL/kg/h), the dialysate sodium concentration and temperature. RESULTS:Median DRT was 180 min (60-420). Ninety five (45%) patients had a DRT ≥ the median value. Mean UFR was 9.2 ± 3.0 mL/kg/h. Patients with a lower DRT had a less prevalent disability in the instrumental activities daily living, had a higher UFR, and a lower dialysate temperature, as compared with subjects with higher DRT. According to the logistic regression model, UFR was associated with a DRT below the median (i.e., 180) in the unadjusted model (OR 1.12; 95% CI 1.02-1.23; p = 0.019), after adjusting for age and sex (OR 1.11; 95% CI 1.01-1.22; p = 0.025), and in the fully adjusted model (OR 1.11; 95% CI 1.04-1.22; p = 0.040). UFR increase was associated with increasing probability of DRT below the median (p for trend = 0.035). The highest tertile of DRT was associated with UFR below the mean value (i.e., 9.2 mL/kg/h) in multinomial logistic regression having the lowest DRT tertile as reference. DRT was significantly lower in patients with UFR > 13 mL/kg/h than in patients with UFR 10-13 or < 10 mL/kg/h. CONCLUSION:DRT is inversely associated with UFR in CHD patients. Whether a high UFR should be recommended to reduce the DRT needs to be elucidated through an adequate prospective randomized study.

journal_name

Blood Purif

journal_title

Blood purification

authors

Bossola M,Di Stasio E,Monteburini T,Parodi E,Ippoliti F,Cenerelli S,Santarelli S,Nebiolo PE,Sirolli V,Bonomini M,Antocicco M,Zuccalà G,Laudisio A

doi

10.1159/000492919

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

45-51

issue

1-3

eissn

0253-5068

issn

1421-9735

pii

000492919

journal_volume

pub_type

临床试验,杂志文章,多中心研究

在线工具

Recovery Time after Hemodialysis Is Inversely Associated with the Ultrafiltration Rate.