Effects of AST-120 on blood concentrations of protein-bound uremic toxins and biomarkers of cardiovascular risk in chronic dialysis patients.

abstract：:Therapeutic plasma exchange (TPE) in neonates and small infants is a treatment method at the forefront that may become a potentially life-saving procedure in a wide array of severe conditions. Indications for TPE in the pediatric population have been mainly derived from adult literature, with neonatal hyperbilirubinem...

journal_title：Blood purification

authors： Vidal E,Garzotto F,Parolin M,Manenti C,Zanin A,Bellettato M,Remuzzi G,Goldstein SL,Murer L,Ronco C

更新日期：2017-01-01 00:00:00

abstract：:In hemodialysis patients, C-reactive protein (CRP), an acute-phase reactant, is a sensitive and independent marker of malnutrition, anemia, and amyloidosis. The aim of the present studies was to evaluate CRP and interleukin 6 levels in plasma samples from long-term hemodialysis patients on different extracorporeal mod...

journal_title：Blood purification

authors： Panichi V,Migliori M,De Pietro S,Metelli MR,Taccola D,Perez R,Palla R,Rindi P,Cristofani R,Tetta C

更新日期：2000-01-01 00:00:00

abstract：:Cuprophane hemodialysis is associated with an early fall of leukocyte counts and an intradialytic rise in serum beta 2-microglobulin (beta 2M), in contrast to dialysis with more compatible dialyzers. It has been suggested that these two phenomena may be related. This study sets out to verify this hypothesis by compari...

journal_title：Blood purification

authors： Vanholder RC,Ringoir SM

更新日期：1990-01-01 00:00:00

abstract：:We report the clinical course of 29 patients with Wegener's granulomatosis (WG) treated with plasma exchange (PE) in Norway in the period from 1988 to 1999. Median follow-up was 41.5 months. The mean number of exchanges was 8.5 +/- 5.8 (range 2-32). Median serum creatinine concentration was 400 micromol/l (range 90-1,...

journal_title：Blood purification

authors： Aasarød K,Iversen BM,Hammerstrøm J,Bostad L,Jørstad S

更新日期：2002-01-01 00:00:00

abstract：:A review is given of the conditions associated with peritoneal membrane failure, and the possible causes. Ultrafiltration failure is the most important manifestation. It is mostly associated with high transport rates of low molecular weight solutes suggesting the presence of a large vascular surface area. Enlargement ...

journal_title：Blood purification

authors： Krediet RT,Van Esch S,Smit W,Michels WM,Zweers MM,Ho-Dac-Pannekeet MM,Struijk DG

更新日期：2002-01-01 00:00:00

abstract：:Renal anemia is the result of reduced erythropoietin (EPO) biosynthesis in the diseased kidney and also in part the result of a reduced life span of red blood cells (RBCs). An increase in density and a decrease in enzyme equipment (aspartate aminotransferase; GOT) of RBCs reflect cell age. In the following study, the ...

journal_title：Blood purification

authors： Hampl H,Riedel E,Wendel G,Scigalla P

更新日期：1990-01-01 00:00:00

abstract：:Numerous experimental and clinical studies suggest that uric acid might have pathobiologic implications in the development and progression of hypertension, kidney disease, and coronary heart disease, among others, resulting in renewed interest in uric acid as a potential pathogenic mediator in these clinical condition...

journal_title：Blood purification

authors： Kanbay M,Solak Y,Gaipov A,Takir M,Weiner DE

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Anticoagulation in hemodialysis (HD) patients at high risk of bleeding remains an intractable problem. Simulating endothelial cells by releasing anticoagulant on the membrane may be a promising alternative. METHODS:We modified a polyacrylonitrile (PAN) dialyzer by loading argatroban into its membrane a...

journal_title：Blood purification

authors： Zhang Y,Ning J,Veeraragoo P,Li Y,Dai S

更新日期：2012-01-01 00:00:00

abstract：AIMS:To study incidence, clinical features, and outcome of critically ill patients with end-stage renal failure (ESRF) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) and to test the validity of severity scoring systems for these patients. METHODS:Data for ESRF patients treated with RRT were...

journal_title：Blood purification

authors： Uchino S,Morimatsu H,Bellomo R,Silvester W,Cole L

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Calcium (Ca) is an essential element that plays a critical role in many biological processes. In dialysis patients, the regulation of Ca balance is highly complex, given the absence of kidney function, endocrine disturbances and the use of drugs such as phosphate binders, vitamin D analogues, and calcimimeti...

journal_title：Blood purification

authors： van der Sande FM,Ter Meulen KJA,Kotanko P,Kooman JP

更新日期：2019-01-01 00:00:00

abstract：:Conventional treatment of acute and chronic renal diseases has focused on solute removal. Novel strategies aim to treat the multifactorial disease states of acute kidney injury and chronic kidney disease by mitigating inflammation. Cell-based technologies for the treatment of kidney dysfunction fall under two broad ca...

journal_title：Blood purification

authors： Pino CJ,Yevzlin AS,Tumlin J,Humes HD

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Peritoneal dialysis (PD) may be a feasible and safe alternative to haemodialysis not only in the chronic but also in the acute setting. It was previously widely accepted as a modality for acute kidney injury (AKI) treatment, but its practice declined in favor of other types of extracorporeal therapies. SUMM...

journal_title：Blood purification

authors： Ponce D,Gobo-Oliveira M,Balbi AL

更新日期：2017-01-01 00:00:00

abstract：:Reprocessing of used dialyzers with chemical disinfectants is practiced commonly in the United States and in some areas of Western Europe. Concern over residual toxic or allergenic agents has encouraged the search for other practical methods to disinfect or sterilize used hemodialyzers. The use of moist heat has been ...

journal_title：Blood purification

authors： Holmes CJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND/AIMS:Secondary hyperparathyroidism (SHP) is characterized by high bone turnover and elevated serum bone remodeling markers. Elevation of serum interleukin-6 (IL-6) levels is also characteristic of end-stage renal disease. This study investigates the effects of intravenous calcitriol on serum bone resorptive ...

journal_title：Blood purification

authors： Lu KC,Tseng CF,Wu CC,Yeung LK,Chen JS,Chao TY,Janckila AJ,Yam LT,Chu P

更新日期：2006-01-01 00:00:00

abstract：:Hypertension is present in most patients with end-stage renal disease and likely contributes to the premature cardiovascular disease in dialysis patients. Previous practice guidelines have recommended that, in patients on chronic dialysis, blood pressure (BP) should be reduced below 130/80 mm Hg. This is based on opin...

journal_title：Blood purification

authors： Redon J,Martinez F,Cheung AK

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The number of patients receiving renal replacement therapy (RRT) increases annually and worldwide. Differences in the RRT incidence, prevalence, and modality vary between regions and countries for reasons yet to be clarified. AIMS:Gain a better understanding of the association between hemodialysis (HD)-rela...

journal_title：Blood purification

authors： Calice-Silva V,Hussein R,Yousif D,Zhang H,Usvyat L,Campos LG,von Gersdorff G,Schaller M,Marcelli D,Grassman A,Etter M,Xu X,Kotanko P,Pecoits-Filho R

更新日期：2015-01-01 00:00:00

abstract：:For maintenance hemodialysis (MHD) patients, the blood is in low hypercoagulable state due to the use of heparin or low molecular weight heparin during dialysis. It is not rare to see hematoma in the puncture site. In recent years, several cases have been reported of spontaneous kidney rupture, but no hip hematoma, le...

journal_title：Blood purification

authors： Ye M,Liu Y,Zhou L,Wang C,Fu X,Peng Y,Liu H

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:Elevated low-density lipoprotein cholesterol and/or lipoprotein(a) are established risk factors for cardiovascular disease (CVD). Management of hypercholesterolemia consists of drug therapies, including statins and proprotein convertase subtilisin/kexin type 9 inhibitors. In patients with familial hy...

journal_title：Blood purification

authors： Raina R,Young C,Krishnappa V,Chanchlani R

更新日期：2019-01-01 00:00:00

abstract：:Critically ill COVID-19 patients are generally admitted to the ICU for respiratory insufficiency which can evolve into a multiple-organ dysfunction syndrome requiring extracorporeal organ support. Ongoing advances in technology and science and progress in information technology support the development of integrated mu...

journal_title：Blood purification

authors： Ronco C,Bagshaw SM,Bellomo R,Clark WR,Husain-Syed F,Kellum JA,Ricci Z,Rimmelé T,Reis T,Ostermann M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND/AIMS:To test the safety and efficacy of the Aethlon Hemopurifier, a lectin affinity cartridge, in clearing hepatitis C virus (HCV) from the blood of HCV-positive end-stage renal disease patients undergoing dialysis. Viral RNA was measured using real-time quantitative reverse transcriptase polymerase chain re...

journal_title：Blood purification

authors： Tullis RH,Duffin RP,Handley HH,Sodhi P,Menon J,Joyce JA,Kher V

更新日期：2009-01-01 00:00:00

abstract：:The EUPHRATES trial (Evaluating Use of Polymyxin B Hemoperfusion in a Randomized Controlled Trial of Adults Treated for Endotoxemia and Septic Shock) is the first biomarker-driven trial in sepsis. This unique trial is being run in a blinded manner, further contributing to the robustness of its design. This paper will ...

journal_title：Blood purification

authors： Foster D,Klein DJ,Guadagni G,Walker PM

更新日期：2014-01-01 00:00:00

abstract：:Heart failure (HF) is a chronic disease process associated with significant morbidity and mortality. Hospitalizations for acute decompensation may be frequent and herald a downward trajectory for the underlying disease state and overall poor prognosis for the patient. While significant advances have been made in the r...

journal_title：Blood purification

authors： Virani SA

更新日期：2008-01-01 00:00:00

abstract：:Backgound: This study was aimed at evaluating the presepsin and procalcitonin levels to predict adverse postoperative complications and mortality in cardiac surgery patients. METHODS:A total of 122 cardiac surgery patients were enrolled for the study. Presepsin and procalcitonin levels were measured 48 h after the pr...

journal_title：Blood purification

authors： Clementi A,Virzì GM,Muciño-Bermejo MJ,Nalesso F,Giavarina D,Carta M,Brocca A,de Cal M,Hinna Danesi T,Zanella M,Marchionna N,Brendolan A,Battaglia GG,Salvador L,Ronco C

更新日期：2019-01-01 00:00:00

abstract：:The greatest benefit of PD ist the continuous maintenance of a stable electrolyte and acid-base balance, as well as a continuous solute, sodium and water removal. Moreover, PD is effective in preserving residual renal function (RRF). However, when RRF declines, complications will occur if not compensated for by an inc...

journal_title：Blood purification

authors： Kawanishi H

更新日期：2004-01-01 00:00:00

abstract：:A strict control of secondary hyperparathyroidism in patients with chronic kidney disease (CKD) is indicated to avoid serious complications linked to osteitis fibrosa and other parathyroid-hormone (PTH)-related bodily disturbances. However, such a control is often achieved only at the price of unacceptably high plasma...

journal_title：Blood purification

authors： Drüeke TB

更新日期：2004-01-01 00:00:00

abstract：:Long-term dialysis in children with multiple handicaps has become easier with the advent of continuous ambulatory peritoneal dialysis (PD). Due to the widespread use of PD and the long survival of patients with spina bifida, an increasing number of patients with spina bifida are on PD. The viability and safety of PD i...

journal_title：Blood purification

authors： Ram Prabahar M,Sivakumar M,Chandrasekaran V,Indhumathi E,Soundararajan P

更新日期：2008-01-01 00:00:00

abstract：:Plasma exchange (PE) is an effective therapeutic method used in patients with myasthenia gravis (MG) refractory to common therapy and/or with life-threatening respiratory complications. Except for acetylcholine receptor antibodies (AChRAbs), some other inflammatory mediators possibly activated in MG may also be remove...

journal_title：Blood purification

authors： Tesar V,Jelínková E,Jirsa M Jr,Bakosová M,Pitha P,Chábová V

更新日期：2000-01-01 00:00:00

abstract：:Continuous arteriovenous hemofiltration requires continuous anticoagulation to prevent early hemofilter clotting. We used heparin given continuously in the arterial line of the extracorporeal circuit as anticoagulant in children with initially normal coagulation status, and heparin and/or prostacyclin in high-risk ble...

journal_title：Blood purification

authors： Zobel G,Trop M,Muntean W,Ring E,Gleispach H

更新日期：1988-01-01 00:00:00

abstract：:In patients with chronic kidney disease (CKD), peptides and proteins circulate at altered concentrations versus in healthy individuals. We have characterized proteome samples from 7 pooled CKD stage 5 patients not yet on dialysis and with no known co-morbidities. We also analyzed pooled plasma samples from 7 healthy a...

journal_title：Blood purification

authors： Naseeb U,Shafqat J,Jägerbrink T,Zarina S,Alvestrand A,Jörnvall H,Axelsson J

更新日期：2008-01-01 00:00:00

abstract：:Cardiovascular disease (CVD) remains the major cause of morbidity and mortality in end-stage renal disease (ESRD) patients. As traditional risk factors cannot alone explain the unacceptable high prevalence and incidence of CVD in this population, inflammation (a common phenomenon in ESRD), and other non-traditional ri...

journal_title：Blood purification

authors： Stenvinkel P,Lindholm B

更新日期：2005-01-01 00:00:00