Development and validation of a new dry weight estimation method using single frequency bioimpedance in hemodialysis patients.

Abstract:

BACKGROUND:We proposed a new method to estimate dry weight (DW) using single frequency bioimpedance. METHODS:We hypothesized that the change in whole body resistance at 50 kHz (R(50)) was proportional to the ultrafiltration volume (UFV) during a hemodialysis (HD) session. When the targeted resistance estimated in healthy subjects was reached, the patient achieved his/her DW. UFV and R(50) were monitored in 40 HD patients. Another 43 HD patients were stratified into 2 groups to validate this method. RESULTS:The change in whole body resistance was proportional to UFV in each of the 40 HD patients. In the DW(decrease) group, pre-dialysis systolic blood pressure (n = 29, 154.5 ± 22.8 vs. 146.9 ± 22.3, p < 0.05) and antihypertensive medicine (4.7 ± 3.6 vs. 3.3 ± 2.2, p < 0.05) decreased without adverse symptoms change. In the DW(increase) group, the number of adverse symptoms in 1 week (n = 14, 26 vs. 6, p < 0.05) decreased without a change in systolic blood pressure. CONCLUSION:This method may become a convenient and cheaper way to estimate DW in HD patients.

journal_name

Blood Purif

journal_title

Blood purification

authors

Dou Y,Cheng X,Liu L,Bai X,Wu L,Guo W,Zhao X,Wang F,Cao L,Zuo L

doi

10.1159/000330337

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

278-85

issue

4

eissn

0253-5068

issn

1421-9735

pii

000330337

journal_volume

32

pub_type

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