Epidemiology of acute renal failure in ICUs: a multi-center prospective study.

Abstract:

BACKGROUND AND AIM:Acute kidney injury (AKI) is a common complication in intensive care units (ICUs). However, its incidence and outcome vary in several studies depending on definitions used or even the geographic origin of the study. We aimed to evaluate the epidemiology of AKI in ICUs in Greece. METHOD:Prospective multicenter study of ICU patients presented with AKI during a 3-month period. RESULTS:One-hundred and seventy patients presented with AKI (16% of total admissions in 23 ICUs). The most common contributing factor to AKI was sepsis (45%). Half of the patients required renal replacement therapy, which was mainly managed by ICU clinicians. Nearly 65% of the AKI patients died, whereas 15% were discharged with renal impairment. Age (RR 1.01, p = 0.046), sepsis (RR 1.62, p = 0.015) and urine output (RR 0.99, p = 0.009) were independently associated with outcome. CONCLUSION:AKI involves a large number of patients in Greek ICUs and is associated with adverse outcomes.

journal_name

Blood Purif

journal_title

Blood purification

authors

Andrikos E,Tseke P,Balafa O,Cruz DN,Tsinta A,Androulaki M,Pappas M,Ronco C

doi

10.1159/000231986

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

239-44

issue

3

eissn

0253-5068

issn

1421-9735

pii

000231986

journal_volume

28

pub_type

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