Application of speckle-tracking echocardiography in detecting coronary artery disease in patients with maintenance hemodialysis.

Abstract:

BACKGROUND:Satisfactory and noninvasive diagnostic tools for coronary artery disease (CAD) are not available in hemodialysis patients. We aimed to elucidate a reliable tool to diagnose CAD in these patients. METHODS:102 hemodialysis patients received 2D speckle-tracking echocardiography with left ventricular (LV) strain analysis and blood tests for cardiac troponin T, high-sensitive C-reactive protein, interleukin (IL)-6, and IL-18. RESULTS:The levels of biomarkers did not differ between patients with and without CAD. The factors associated with CAD were decreased circumferential strain, decreased global longitudinal strain, and the number of LV segments with decreased longitudinal strain. Logistic regression analyses showed that the number of LV segments with decreased longitudinal strain, over 6 segments, was strongly associated with CAD in hemodialysis patients (OR 12.08, 95% CI 3.724-39.209). CONCLUSIONS:The noninvasive modality of speckle-tracking echocardiography with strain analysis is efficient and objective for identifying CAD in hemodialysis patients.

journal_name

Blood Purif

journal_title

Blood purification

authors

Liu YW,Su CT,Wang SP,Yang CS,Huang JW,Hung KY,Chen JH,Tsai WC

doi

10.1159/000323536

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

38-42

issue

1

eissn

0253-5068

issn

1421-9735

pii

000323536

journal_volume

32

pub_type

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