Extracellular water/intracellular water is a strong predictor of patient survival in incident peritoneal dialysis patients.

Abstract:

BACKGROUND:The mortality rate of peritoneal dialysis (PD) patients is still high and controversies persist regarding the mortality predictor. This study was designed to identify the predictability of the extracellular water/intracellular water ratio (E/I) on mortality in PD patients. METHODS:227 incident PD patients were included. Time-dependent Cox proportional hazard regression was used to investigate the predictability of E/I on mortality. RESULTS:The 2- and 3-year survival was 74 and 65%, respectively. Univariate Cox proportional hazard regression analysis showed that the significant predictors of mortality were age, sex, Charlson Comorbidity Index, total Kt/V, serum albumin, pulse pressure, presence of malnutrition, and E/I. However, the final Cox proportional hazard models revealed that E/I was the only significant predictor. For every increase of 0.1 in the E/I value, the relative risk of death was 1.368. CONCLUSIONS:E/I is a strong independent predictor of mortality in incident PD patients.

journal_name

Blood Purif

journal_title

Blood purification

authors

Chen W,Guo LJ,Wang T

doi

10.1159/000101699

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

260-6

issue

3

eissn

0253-5068

issn

1421-9735

pii

000101699

journal_volume

25

pub_type

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