Significance of Content of the Reticulocyte Hemoglobin in the Management of Renal Anemia.

Abstract:

:Optimal iron level in hemodialysis patients remains a subject of debate. The reticulocyte hemoglobin content (CHr) is believed to reflect the concentration of iron required in the most recent hematopoiesis in the bone marrow. CHr is not influenced by any factors that measure direct hemoglobin (Hb) of reticulocytes and is considered a reliable indicator. The supply of iron for Hb synthesis is regulated by hepcidin-25 (Hep-25). However, CHr and Hep-25 measurements are not covered by the Japanese medical insurance system. Serum ferritin (s-ft) and transferrin saturation (TSAT) are used mainly as indicators of internal iron status. Therefore, we examined the relationships among CHr, s-ft, TSAT, and Hep-25 to determine the optimal iron level. This report presents the clinical significance of CHr, the potential use of CHr for the diagnosis of iron deficiency, and tests for optimal iron level using CHr as performed in our hospital.

journal_name

Blood Purif

journal_title

Blood purification

authors

Ogawa C,Tsuchiya K,Nitta K,Maeda K

doi

10.1159/000496641

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

70-73

eissn

0253-5068

issn

1421-9735

pii

000496641

journal_volume

47 Suppl 2

pub_type

杂志文章
  • Effects of AST-120 on blood concentrations of protein-bound uremic toxins and biomarkers of cardiovascular risk in chronic dialysis patients.

    abstract:BACKGROUND:Removal of protein-bound uremic toxins by dialysis therapy is limited. The effect of oral adsorbent AST-120 in chronic dialysis patients has rarely been investigated. METHODS:AST-120 was administered 6.0 g/day for 3 months in 69 chronic dialysis patients. The blood concentrations of indoxyl sulfate, p-creso...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000357641

    authors: Lee CT,Hsu CY,Tain YL,Ng HY,Cheng BC,Yang CC,Wu CH,Chiou TT,Lee YT,Liao SC

    更新日期:2014-01-01 00:00:00

  • Role of Lipoprotein Apheresis in Cardiovascular Disease Risk Reduction.

    abstract:BACKGROUND AND AIM:Elevated low-density lipoprotein cholesterol and/or lipoprotein(a) are established risk factors for cardiovascular disease (CVD). Management of hypercholesterolemia consists of drug therapies, including statins and proprotein convertase subtilisin/kexin type 9 inhibitors. In patients with familial hy...

    journal_title:Blood purification

    pub_type: 杂志文章,meta分析,评审

    doi:10.1159/000497447

    authors: Raina R,Young C,Krishnappa V,Chanchlani R

    更新日期:2019-01-01 00:00:00

  • Prevention and management of dialysis catheter complications in the intensive care unit.

    abstract::Dialysis dependence at hospital discharge after acute kidney injury (AKI) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) is found in 10-15% of survivors. In case of severe AKI in the ICU, it is necessary to reconcile two objectives: the creation of an adequate temporary angioaccess for RRT ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000341721

    authors: Wilson P,Lertdumrongluk P,Leray-Moragués H,Chenine-Koualef L,Patrier L,Canaud B

    更新日期:2012-01-01 00:00:00

  • Membrane-Based Therapeutic Plasma Exchange in Intensive Care.

    abstract::The principles and use of plasmapheresis are often little understood by intensivists. We propose to review the principles, the main indications, and the methods of using this technique. ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000510983

    authors: Redant S,De Bels D,Ismaili K,Honoré PM

    更新日期:2020-10-22 00:00:00

  • The Effect of Increased Frequency of Hemodialysis on Volume-Related Outcomes: A Secondary Analysis of the Frequent Hemodialysis Network Trials.

    abstract::In previous reports of the Frequent Hemodialysis Network trials, frequent hemodialysis (HD) reduced extracellular fluid (ECF) and left ventricular mass (LVM), with more pronounced effects observed among patients with low urine volume (UVol). We analyzed the effect of frequent HD on interdialytic weight gain (IDWG) and...

    journal_title:Blood purification

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000441966

    authors: Raimann JG,Chan CT,Daugirdas JT,Depner T,Gotch FA,Greene T,Kaysen GA,Kliger AS,Kotanko P,Larive B,Lindsay R,Rocco MV,Chertow GM,Levin NW,Frequent Hemodialysis Network (FHN) Trial Group.

    更新日期:2016-01-01 00:00:00

  • What can we expect from on-line hemodiafiltration?

    abstract::On-line hemodiafiltration (ol-HDF) may improve clinical outcome in ESRD. The supposed mechanism is the improved clearance of uremic toxins by convective transport which is added to the diffusion transport. However, recent marked improvement in the performance of dialyzers has allowed higher removal rate of middle to l...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000346217

    authors: Kawanishi H

    更新日期:2013-01-01 00:00:00

  • Application of speckle-tracking echocardiography in detecting coronary artery disease in patients with maintenance hemodialysis.

    abstract:BACKGROUND:Satisfactory and noninvasive diagnostic tools for coronary artery disease (CAD) are not available in hemodialysis patients. We aimed to elucidate a reliable tool to diagnose CAD in these patients. METHODS:102 hemodialysis patients received 2D speckle-tracking echocardiography with left ventricular (LV) stra...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000323536

    authors: Liu YW,Su CT,Wang SP,Yang CS,Huang JW,Hung KY,Chen JH,Tsai WC

    更新日期:2011-01-01 00:00:00

  • Enhanced functional performance characteristics of a new polysulfone membrane for high-flux hemodialysis.

    abstract::Elimination of uremic solutes with molecular weights up to 60 kD, without significant loss of albumin is an important therapeutic goal to optimize outcomes in chronic hemodialysis patients. To characterize a newly developed polysulfone dialyzer (APS-650) a comparative analysis was performed with a highly advanced poly...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000063099

    authors: Klingel R,Ahrenholz P,Schwarting A,Röckel A

    更新日期:2002-01-01 00:00:00

  • Impact of acute renal failure on the relationship between N-terminal pro-B-type natriuretic peptide and hemodynamic parameters.

    abstract:BACKGROUND:We studied the influence of acute renal failure (ARF) on the relationship between N-terminal pro-B-type natriuretic peptide (NT-proBNP) and hemodynamic parameters. METHODS:The echocardiographic parameters and NT-proBNP levels were compared between 26 mechanically ventilated patients with ARF requiring conti...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000322259

    authors: Balik M,Jabor A,Otahal M,Waldauf P,Pavlisova M

    更新日期:2011-01-01 00:00:00

  • Peritoneal dialysis in Europe: an analysis of its rise and fall.

    abstract::There is a wide variability in the utilization of peritoneal dialysis throughout Europe that cannot be explained by differences in medical factors alone. Over the last years, the utilization of peritoneal dialysis has even changed in individual countries. The main factors of this variation are not medical, but rather ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000089446

    authors: Lameire N,Peeters P,Vanholder R,Van Biesen W

    更新日期:2006-01-01 00:00:00

  • Recovery Time after Hemodialysis Is Inversely Associated with the Ultrafiltration Rate.

    abstract:INTRODUCTION:The present study aimed to determine the variables that are associated with a longer dialysis recovery time (DRT) and to define the relationship that exists between DRT and the ultrafiltration rate (UFR) in prevalent chronic hemodialysis (CHD) patients. METHODS:We studied 210 prevalent CHD of 5 hemodialys...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1159/000492919

    authors: Bossola M,Di Stasio E,Monteburini T,Parodi E,Ippoliti F,Cenerelli S,Santarelli S,Nebiolo PE,Sirolli V,Bonomini M,Antocicco M,Zuccalà G,Laudisio A

    更新日期:2019-01-01 00:00:00

  • When should renal replacement therapy for acute kidney injury be initiated and discontinued?

    abstract:BACKGROUND:Critically ill patients with acute kidney injury (AKI) are at high risk for death and frequently require initiation of renal replacement therapy (RRT). There is wide variation in clinical practice on the indications for and timing of initiation and discontinuation of RRT. Numerous clinical and biochemical fa...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000157325

    authors: Gibney RT,Bagshaw SM,Kutsogiannis DJ,Johnston C

    更新日期:2008-01-01 00:00:00

  • Strategies for the Super-Aged Dialysis Population: Survival Benefits or Alternative Goals?

    abstract:BACKGROUND/AIMS:Japan's aging population has prominent epidemiological and patient characteristics. The number of hemodialysis patients aged ≥70 years is increasing. Age-adjusted mortality is improving, but some cause-specific mortalities remain unchanged, including infectious disease and malignancy, requiring combativ...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000496660

    authors: Sakurai S,Hanafusa N,Nomura T,Tsuchiya K,Nitta K,Nangaku M

    更新日期:2019-01-01 00:00:00

  • Anorexia and malnutrition in hemodialysis patients.

    abstract::Malnutrition, which is common in maintenance hemodialysis (HD) patients, is strongly associated with increased morbidity and mortality. Protein requirements in HD patients are increased twice or more compared to those of healthy subjects. Underdialysis leads to anorexia with low protein and energy intake in relation t...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000170072

    authors: Bergström J

    更新日期:1992-01-01 00:00:00

  • Plasma dimethylarginine levels in chronic hemodialysis patients are independent of the type of dialyzer applied.

    abstract:BACKGROUND:Asymmetric dimethylarginine (ADMA) levels are increased in hemodialysis (HD) patients. Reports on the effect of various dialysis strategies on ADMA, symmetric dimethylarginine (SDMA) and L-arginine levels are inconclusive. PATIENTS/METHODS:In this randomized crossover study, 15 patients were dialyzed for 4 ...

    journal_title:Blood purification

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000104868

    authors: Grooteman MP,Wauters IM,Teerlink T,Twisk JW,Nubé MJ

    更新日期:2007-01-01 00:00:00

  • Soluble adhesion molecules and cytokines in patients with myasthenia gravis treated by plasma exchange.

    abstract::Plasma exchange (PE) is an effective therapeutic method used in patients with myasthenia gravis (MG) refractory to common therapy and/or with life-threatening respiratory complications. Except for acetylcholine receptor antibodies (AChRAbs), some other inflammatory mediators possibly activated in MG may also be remove...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000014434

    authors: Tesar V,Jelínková E,Jirsa M Jr,Bakosová M,Pitha P,Chábová V

    更新日期:2000-01-01 00:00:00

  • Alleviation of cisplatin nephrotoxicity: efficacy of local intra-arterial injection concomitant with hemodialysis.

    abstract::Although cis-diamminedichloroplatinum (cisplatin) is widely used in the treatment of malignant tumors, the dose administered is limited because of side effects such as nephrotoxicity. The plasma levels of non-protein-bound platinum, which can be removed by dialysis, play an important role in the antitumor effects and ...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章

    doi:10.1159/000170256

    authors: Yura T,Badr KF,Yuasa S,Kurose T,Ohkawa M,Hando T,Fukunaga M,Matsuo H

    更新日期:1996-01-01 00:00:00

  • Effect of Sedative-Hypnotic Medicines on Mortality in Peritoneal Dialysis Patients with Sleep Disorders: A Retrospective Cohort Study.

    abstract:BACKGROUND:Sedative-hypnotic medication is widely used among continuous ambulatory peritoneal dialysis (CAPD) patients with sleep disorders; however, its effect on mortality has rarely been investigated. METHODS:Logistic regression was employed to identify factors associated with sedative-hypnotic medication, whose ef...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章

    doi:10.1159/000484922

    authors: Zhou Y,Yin P,Li B,Li J,Huang N,Wu H,Ullah H,Yang X,Yu X

    更新日期:2018-01-01 00:00:00

  • Microcirculation: Physiology, Pathophysiology, and Clinical Application.

    abstract::This paper briefly reviews the physiological components of the microcirculation, focusing on its function in homeostasis and its central function in the realization of oxygen transport to tissue cells. Its pivotal role in the understanding of circulatory compromise in states of shock and renal compromise is discussed....

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000503775

    authors: Guven G,Hilty MP,Ince C

    更新日期:2020-01-01 00:00:00

  • A case of McLeod syndrome with chronic renal failure.

    abstract::A 50-year-old man with the rare McLeod syndrome, associated with glomerular lesion to the end stage of chronic renal failure and death, is reported. McLeod syndrome is an X-linked recessive disorder on the basis of abnormal expression of the Kell blood group antigens and absence of erythrocyte surface Kx antigen. Most...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000014353

    authors: Jeren-Strujić B,Jeren T,Thaller N,Zivković Z,Raos V

    更新日期:1998-01-01 00:00:00

  • Advances and advantages in recent central dialysis fluid delivery system.

    abstract::The central dialysis fluid delivery system (CDDS) has been working exclusively in Japan since 1970, a fact which proves that CDDS is useful in the multi-patient treatment with in-center regular hemodialysis. It is a cost-effective, labor-saving and time-tested system with 40 years of experience. Microbial safety is im...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000213494

    authors: Koda Y,Mineshima M

    更新日期:2009-01-01 00:00:00

  • Is There Enough Evidence to Prove That Hemodiafiltration Is Superior?

    abstract::The evidence concerning online hemodiafiltration (HDF) includes the following: (1) the increase of removal of uremic toxin, (2) the prevention of dialysis rerated hypotension, (3) the recovery of survival, and (4) the recovery of dialysis related uncertain symptoms. Although clinical evidence has been noted, the hypot...

    journal_title:Blood purification

    pub_type: 社论

    doi:10.1159/000487917

    authors: Kawanishi H

    更新日期:2018-01-01 00:00:00

  • Polymorphonuclear oxygen free radical production and complement activation induced by dialysis membranes as assayed in an experimental model.

    abstract::Activation of polymorphonuclear leukocytes with subsequent production of reactive oxygen metabolites has been reported to occur during hemodialysis related to a membrane bioincompatibility. We used an experimental dialysis model to evaluate, by chemiluminescence, the production of reactive oxygen metabolites and, by C...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000169604

    authors: Cappelli G,Lucchi L,Bonucchi D,Cenci AM,Montagnani G,De Palma M,Lusvarghi E

    更新日期:1989-01-01 00:00:00

  • Amino acids and keto acids in the treatment of chronic renal failure.

    abstract::Clinical trials using very low protein supply supplemented with amino acid or keto acid preparations have shown the possibility of slowing the rate of decline of renal function in patients with advanced chronic renal failure together with preservation of nutritional status. The possible mechanisms by which this effect...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章,评审

    doi:10.1159/000169557

    authors: Jungers P,Chauveau P

    更新日期:1988-01-01 00:00:00

  • Natural killer cell dysfunction in uremia: the role of oxidative stress and the effects of dialysis.

    abstract::Immune deficiency is one of the numerous consequences of chronic renal failure. We can hypothesize that an abnormal natural killer (NK) cell response is present in patients with end-stage renal disease (ESRD). To characterize the immune defect in ESRD patients, we performed a NK cell subset analysis in 66 patients wit...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000350839

    authors: Peraldi MN,Berrou J,Métivier F,Toubert A

    更新日期:2013-01-01 00:00:00

  • Dietary and pharmacological control of calcium and phosphate metabolism in dialysis patients.

    abstract::Chronic kidney disease-mineral and bone disorder is a new term defining a complex syndrome which underlines the need of a systemic approach to disturbances of calcium and phosphate metabolism in patients with renal failure. In recent years, the availability of new phosphorus binders and the appearance of new selective...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000209250

    authors: Bover J,Andrés E,Lloret MJ,Aguilar A,Ballarín J

    更新日期:2009-01-01 00:00:00

  • Peritoneal membrane failure in peritoneal dialysis patients.

    abstract::A review is given of the conditions associated with peritoneal membrane failure, and the possible causes. Ultrafiltration failure is the most important manifestation. It is mostly associated with high transport rates of low molecular weight solutes suggesting the presence of a large vascular surface area. Enlargement ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000065202

    authors: Krediet RT,Van Esch S,Smit W,Michels WM,Zweers MM,Ho-Dac-Pannekeet MM,Struijk DG

    更新日期:2002-01-01 00:00:00

  • Effects of calcitriol on type 5b tartrate-resistant acid phosphatase and interleukin-6 in secondary hyperparathyroidism.

    abstract:BACKGROUND/AIMS:Secondary hyperparathyroidism (SHP) is characterized by high bone turnover and elevated serum bone remodeling markers. Elevation of serum interleukin-6 (IL-6) levels is also characteristic of end-stage renal disease. This study investigates the effects of intravenous calcitriol on serum bone resorptive ...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1159/000094899

    authors: Lu KC,Tseng CF,Wu CC,Yeung LK,Chen JS,Chao TY,Janckila AJ,Yam LT,Chu P

    更新日期:2006-01-01 00:00:00

  • Plasma Biomarkers in Predicting Renal Recovery from Acute Kidney Injury in Critically Ill Patients.

    abstract:BACKGROUND:Numerous studies have suggested a possible role for acute kidney injury (AKI) biomarkers in predicting renal recovery both before and after renal replacement therapy (RRT). However, definitions for recovery and whether to include patients dying but free of RRT may influence results. OBJECTIVES:To validate p...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000500423

    authors: Fiorentino M,Tohme FA,Murugan R,Kellum JA

    更新日期:2019-01-01 00:00:00

  • Improvements in technology: a path to safer and more effective hemodialysis.

    abstract::Effective dialysis therapy is now understood to encompass both small and large solute removal, using approaches that minimize intradialytic symptoms and maximize patient safety. Achieving the goal of providing effective dialysis for an expanding population of patients with increasingly complex medical problems at a ti...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000167001

    authors: Ward RA,Ronco C

    更新日期:2009-01-01 00:00:00