In vitro clearance and hemocompatibility assessment of ultrathin nanoporous silicon membranes for hemodialysis applications using human whole blood.

abstract：BACKGROUND:It was recently reported that the severity of coronary and carotid atherosclerosis in patients with end-stage kidney disease (ESKD) has improved over the last two decades. However, the frequency of coronary artery events observed at the initiation of dialysis remains high. SUMMARY:Recently, 5 different clin...

journal_title：Blood purification

authors： Tanaka Y,Joki N,Hase H

更新日期：2015-01-01 00:00:00

abstract：:Thirty-four patients with end-stage renal disease requiring hemodialysis developed over the course of 7 years (1987-1994) severe ischemia in the extremity carrying the angioaccess secondary to arterial 'steal'. Seven of these patients were treated with access ligation, 4 with banding reducing the flow through the acce...

journal_title：Blood purification

authors： Haimov M,Schanzer H,Skladani M

更新日期：1996-01-01 00:00:00

abstract：:The administration of intravenous fluids is perhaps the most common treatment given in the intensive care unit. According to biologic rationale, ongoing fluid losses should be replaced to maintain fluid homeostasis and relative or absolute deficiencies in circulating blood volume should be prevented or rapidly correct...

journal_title：Blood purification

authors： Bellomo R

更新日期：2002-01-01 00:00:00

abstract：:Continuous arteriovenous hemofiltration requires continuous anticoagulation to prevent early hemofilter clotting. We used heparin given continuously in the arterial line of the extracorporeal circuit as anticoagulant in children with initially normal coagulation status, and heparin and/or prostacyclin in high-risk ble...

journal_title：Blood purification

authors： Zobel G,Trop M,Muntean W,Ring E,Gleispach H

更新日期：1988-01-01 00:00:00

abstract：:The study was made in vitro of reactions elicited by contact of granulocytes suspended in autologous plasma with three polymers: polyacrylonitrile (AN); polyetherpoly-carbonate (PC), and regenerated cellulose (Cu). Alterations in basal metabolism and biological function of the human blood granulocytes induced by inter...

journal_title：Blood purification

authors： Ikomi-Kumm J,Ljunggren L,Lund U,Monti M,Thysell H

更新日期：1991-01-01 00:00:00

abstract：:The second law of thermodynamics applies with local exceptions to patient history and therapy interventions. Living things preserve their low level of entropy throughout time because they receive energy from their surroundings in the form of food. They gain their order at the expense of disordering the nutrients they ...

journal_title：Blood purification

authors： Ronco C

更新日期：2013-01-01 00:00:00

abstract：:A group of patients with severe anemia on standard hemodialysis were transferred to polyacrylnitrile hemodiafiltration (HDF), which was arranged in order to obtain an ultrafiltration rate (UF) higher than 100 ml/min. During HDF, despite a significant reduction of the dialysis time, all patients had a significant decre...

journal_title：Blood purification

authors： Gonella M,Pratesi G,Calabrese G,Vagelli G,Mazzotta A

更新日期：1989-01-01 00:00:00

abstract：:The mortality from sepsis complicated by renal failure remains extremely high despite the application of modern renal replacement therapy. This study investigated whether treatment with a bioartificial kidney consisting of a hemofilter in a continuous venovenous hemofiltration circuit (CVVH) with a cartridge containin...

journal_title：Blood purification

authors： Fissell WH,Dyke DB,Weitzel WF,Buffington DA,Westover AJ,MacKay SM,Gutierrez JM,Humes HD

更新日期：2002-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is a common complication in pediatric and neonatal intensive care units (ICU). Renal replacement therapy (RRT) is frequently needed in children in whom supportive therapy is not enough to satisfy their metabolic demands or to be able to provide adequate nutrition. The decision to begin dialys...

journal_title：Blood purification

authors： Bonilla-Félix M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Hemoadsorption may improve outcomes for sepsis by removing circulating cytokines. We tested a new sorbent used for hemoadsorption. METHODS:CTR sorbent beads were filled into columns of three sizes: CTR0.5 (0.5 ml), CTR1 (1.0 ml) and CTR2 (2.0 ml) and tested using IL-6 capture in vitro. Next, rats were ...

journal_title：Blood purification

authors： Zhang J,Peng Z,Maberry D,Volpe J,Kimmel JD,Federspiel WJ,Kellum JA

更新日期：2015-01-01 00:00:00

abstract：:Although cis-diamminedichloroplatinum (cisplatin) is widely used in the treatment of malignant tumors, the dose administered is limited because of side effects such as nephrotoxicity. The plasma levels of non-protein-bound platinum, which can be removed by dialysis, play an important role in the antitumor effects and ...

journal_title：Blood purification

authors： Yura T,Badr KF,Yuasa S,Kurose T,Ohkawa M,Hando T,Fukunaga M,Matsuo H

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Calcium (Ca) is an essential element that plays a critical role in many biological processes. In dialysis patients, the regulation of Ca balance is highly complex, given the absence of kidney function, endocrine disturbances and the use of drugs such as phosphate binders, vitamin D analogues, and calcimimeti...

journal_title：Blood purification

authors： van der Sande FM,Ter Meulen KJA,Kotanko P,Kooman JP

更新日期：2019-01-01 00:00:00

abstract：:We have investigated the effect of the direction of the dialysate flow during continuous arteriovenous haemodialysis. Under similar conditions countercurrent flow was more efficient than concurrent flow in terms of both urea clearance (mean +/- SEM), 23.5 +/- 0.5 compared to 18.4 +/- 0.4 ml/min (p less than 0.001) and...

journal_title：Blood purification

authors： Davenport A,Will EJ,Davison AM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Renal medullary hypoxia precedes the development of acute kidney injury in experimental sepsis and can now be assessed by continuous measurement of urinary oxygen tension (PuO2). OBJECTIVES:We aimed to test if PuO2 measurements in patients with septic shock would be similar to those shown in experimental se...

journal_title：Blood purification

authors： Osawa EA,Cutuli SL,Bitker L,Canet E,Cioccari L,Iguchi N,Lankadeva YR,Eastwood GM,Evans RG,May CN,Bellomo R

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Japan's aging population has prominent epidemiological and patient characteristics. The number of hemodialysis patients aged ≥70 years is increasing. Age-adjusted mortality is improving, but some cause-specific mortalities remain unchanged, including infectious disease and malignancy, requiring combativ...

journal_title：Blood purification

authors： Sakurai S,Hanafusa N,Nomura T,Tsuchiya K,Nitta K,Nangaku M

更新日期：2019-01-01 00:00:00

abstract：:Many organic solutes accumulate in end-stage renal disease (ESRD) and some are poorly removed with urea-based prescriptions for hemodialysis. However, their toxicities have been difficult to assess. We have employed an animal model, the zebrafish embryo, to test the toxicity of uremic serum compared to control. Serum ...

journal_title：Blood purification

authors： Berman N,Lectura M,Thurman J,Reinecke J,Raff AC,Melamed ML,Reinecke J,Quan Z,Evans T,Meyer TW,Hostetter TH

更新日期：2013-01-01 00:00:00

abstract：:In this work we investigated the acute effects of hemodiafiltration with endogenous reinfusion (HFR therapy) on the removal of free immunoglobulin light chains (FIgLCs), which may be considered members of the family of uremic toxins. In two groups of patients - group 1 (polyclonal FIgLCs production) and group 2 (monoc...

journal_title：Blood purification

authors： Testa A,Dejoie T,Lecarrer D,Wratten M,Sereni L,Renaux JL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Frequent hemodialysis (HD) may be associated with an increased risk of vascular access complications. Studies addressing vascular access outcomes in frequent HD show conflicting results. METHODS:We searched Medline for trials looking at vascular access outcomes in frequent HD. RESULTS:Nineteen studies met ...

journal_title：Blood purification

authors： Cornelis T,Usvyat LA,Tordoir JH,Wang Y,Wong M,Leunissen KM,van der Sande FM,Kotanko P,Kooman JP

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Various cytokines are increased in hemodialysis (HD) patients, and are considered prognostic markers. Metabolic acidosis is common among chronic HD patients and is associated with survival. The relationship between acidosis and cytokines in HD patients has not been fully explored. The study aim was to measur...

journal_title：Blood purification

authors： Ori Y,Bergman M,Bessler H,Zingerman B,Levy-Drummer RS,Gafter U,Salman H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Some angiotensin converting enzyme (ACE) inhibitors are efficiently removed from circulation by hemodialysis ('high dialyzability'), whereas others are not ('low dialyzability'). In patients receiving hemodialysis, this may influence the effectiveness of ACE inhibitors. METHODS:Using linked healthcare ...

journal_title：Blood purification

authors： Weir MA,Fleet JL,Dixon SN,Jain AK,Oliver M,Wald R,McIntyre C,Garg AX

更新日期：2015-01-01 00:00:00

abstract：:To evaluate objectively the effects of recombinant human erythropoietin (rHuEPO) administration on nutritional status in stable dialyzed patients, we used urea kinetic modeling (UKM) analysis and dietary protein intake evaluation by dietary assessment. Fifteen patients (9 females, 6 males; mean age 46.9 +/- 15.6 years...

journal_title：Blood purification

authors： Canaud B,Bouloux C,Rivory JP,Taib J,Garred LJ,Florence P,Mion C

更新日期：1990-01-01 00:00:00

abstract：:The recent recognition that hyperphosphatemia is a strong predictor of survival on dialysis has rekindled interest in the regulation and control of serum phosphate. In incipient renal failure hyperphosphatemia is prevented by increased fractional renal phosphate excretion mediated via an increase in parathyroid hormon...

journal_title：Blood purification

authors： Ritz E,Gross ML

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Intravenous iron infusion is the accepted way of supplementation of that compound in uremic patients. The aim of the study was to evaluate whether this treatment affects intraperitoneal homeostasis in patients on peritoneal dialysis. METHODS:Blood and peritoneal dialysate samples were collected from 10...

journal_title：Blood purification

authors： Breborowicz A,Połubinska A,Kupczyk M,Wanic-Kossowka M,Oreopoulos DG

更新日期：2009-01-01 00:00:00

abstract：:The principles and use of plasmapheresis are often little understood by intensivists. We propose to review the principles, the main indications, and the methods of using this technique. ...

journal_title：Blood purification

authors： Redant S,De Bels D,Ismaili K,Honoré PM

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:Dialysis patients have higher cardiovascular events rate than patients with normal renal function. Hyperhomocysteinemia, a risk factor for cardiovascular disease, is frequently detected in dialysis patients. Vitamin B supplementation lowers hyperhomocysteinemia, but it is unknown whether it reduces cardiovas...

journal_title：Blood purification

authors： Righetti M,Serbelloni P,Milani S,Ferrario G

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND AIM:Acute kidney injury (AKI) is a common complication in intensive care units (ICUs). However, its incidence and outcome vary in several studies depending on definitions used or even the geographic origin of the study. We aimed to evaluate the epidemiology of AKI in ICUs in Greece. METHOD:Prospective m...

journal_title：Blood purification

authors： Andrikos E,Tseke P,Balafa O,Cruz DN,Tsinta A,Androulaki M,Pappas M,Ronco C

更新日期：2009-01-01 00:00:00

abstract：:Recently, a new type of modified cellulosic membrane (Hemophan) has been made available for the first clinical trials. In contrast to cellulose acetate membranes only about 5% of the hydroxyl groups of cellulose are substituted by tertiary amino groups. Objective of the present study was to assess the compatibility pe...

journal_title：Blood purification

authors： Schaefer RM,Hörl WH,Kokot K,Heidland A

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND/AIMS:Sudden K removal is thought to be implicated in ECG alterations observed during hemodialysis (HD). The effects of the K removal rate on ECG-derived parameters have been investigated. METHODS:Two different hemodiafiltration (HDF) schedules were used for 10 HD patients: the dialysate K concentration was ...

journal_title：Blood purification

authors： Severi S,Vecchietti S,Cavalcanti S,Mancini E,Santoro A

更新日期：2003-01-01 00:00:00

abstract：AIMS:To study incidence, clinical features, and outcome of critically ill patients with end-stage renal failure (ESRF) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) and to test the validity of severity scoring systems for these patients. METHODS:Data for ESRF patients treated with RRT were...

journal_title：Blood purification

authors： Uchino S,Morimatsu H,Bellomo R,Silvester W,Cole L

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:Carpal tunnel syndrome (CTS) is a common clinical presentation of dialysis-related amyloidosis. It was determined whether β(2)-microglobulin (β2M) and advanced glycation end products in serum are predictors of CTS in dialysis patients. METHODS:A total of 385 hemodialysis patients were screened for CTS....

journal_title：Blood purification

authors： Busch M,Schwenzky A,Franke S,Stein G,Wolf G

更新日期：2012-01-01 00:00:00