Microcalorimetric evaluation of blood compatibility of hemodialysis membranes.

Abstract:

:The study was made in vitro of reactions elicited by contact of granulocytes suspended in autologous plasma with three polymers: polyacrylonitrile (AN); polyetherpoly-carbonate (PC), and regenerated cellulose (Cu). Alterations in basal metabolism and biological function of the human blood granulocytes induced by interfacial reactions were determined by direct microcalorimetry. The polymers, which are commonly used as membranes in artificial kidneys, were found to activate granulocytes to degrees which were inversely correlated with their response to zymosan. The compatibility of the granulocytes and each of the membranes was of the order: AN greater than PC greater than Cu.

journal_name

Blood Purif

journal_title

Blood purification

authors

Ikomi-Kumm J,Ljunggren L,Lund U,Monti M,Thysell H

doi

10.1159/000170015

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

177-81

issue

4

eissn

0253-5068

issn

1421-9735

journal_volume

9

pub_type

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