Abstract:
:To increase the efficiency of continuous arteriovenous hemofiltration (CAVH) in cases of severe catabolism, we used a modified CAVH treatment, called arteriovenous hemodiafiltration (AVHDF), in 4 patients. The transport of solutes was increased by providing the infusion of a counter current flow of urea-free solutions in the UF compartment of a standard CAVH circuit. Patients were treated with standard CAVH and, when a more efficient treatment was required, intermittent daily sessions of AVHDF were performed using the same filter and lines. The urea kinetic study enabled the calculation of the time needed to perform AVHDF, in addition to standard CAVH, to maintain the blood urea nitrogen (BUN) level under control. A dialysate flow rate of 300 ml/min made it possible to increase the urea nitrogen mass transfer rate from 10 to 65 mg/min and the clearance from 10.5 to 37.5 ml/min. The addition of AVHDF to CAVH enabled the control of BUN levels in the 4 patients affected by acute renal failure and a severe catabolic state. The technique is simple, does not require additional devices, and maintains the advantages of CAVH providing a better efficiency in terms of solute removal.
journal_name
Blood Purifjournal_title
Blood purificationauthors
Ronco C,Brendolan A,Bragantini L,Chiaramonte S,Fabris A,Feriani M,Dell'Aquila R,Milan M,La Greca Gdoi
10.1159/000169454subject
Has Abstractpub_date
1987-01-01 00:00:00pages
33-40issue
1eissn
0253-5068issn
1421-9735journal_volume
5pub_type
杂志文章abstract::Hypertension is present in most patients with end-stage renal disease and likely contributes to the premature cardiovascular disease in dialysis patients. Previous practice guidelines have recommended that, in patients on chronic dialysis, blood pressure (BP) should be reduced below 130/80 mm Hg. This is based on opin...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000245631
更新日期:2010-01-01 00:00:00
abstract::Dialysis dependence at hospital discharge after acute kidney injury (AKI) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) is found in 10-15% of survivors. In case of severe AKI in the ICU, it is necessary to reconcile two objectives: the creation of an adequate temporary angioaccess for RRT ...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000341721
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIM:The relationship between body mass index (BMI) and intradialytic hypotension (IDH) has been inconsistently reported, but no further research has investigated the correlation between body composition and IDH so far. This study aimed to determine whether the lean tissue index (LTI), fat tissue index (FTI),...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000504245
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:To study calcium homeostasis during citrate-based compared to nadroparin-based CVVH in critically-ill patients with acute renal failure. METHODS:11 patients were observed during citrate anticoagulation, 9 with nadroparin and 10 controls. Citrate was chosen for patients with active or at risk for bleeding. ...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000101853
更新日期:2007-01-01 00:00:00
abstract::Heart failure results in significant morbidity and mortality in the United States. Chronic heart failure is often complicated by renal insufficiency. Further, acute decompensated heart failure is often complicated by worsening renal function or the development of diuretic resistance. Heart failure complicated by renal...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000207198
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND/AIMS:Intravenous iron infusion is the accepted way of supplementation of that compound in uremic patients. The aim of the study was to evaluate whether this treatment affects intraperitoneal homeostasis in patients on peritoneal dialysis. METHODS:Blood and peritoneal dialysate samples were collected from 10...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000210038
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:This study was aimed at evaluating the efficacy and safety of regional citrate anticoagulation (RCA) versus no-anticoagulation continuous venovenous hemofiltration (CVVH) in acute severe hypernatremia patients with increased bleeding risk. MATERIALS AND METHODS:Acute severe hypernatremia patients with high ble...
journal_title:Blood purification
pub_type: 临床试验,杂志文章
doi:10.1159/000502937
更新日期:2020-01-01 00:00:00
abstract::Clinical trials using very low protein supply supplemented with amino acid or keto acid preparations have shown the possibility of slowing the rate of decline of renal function in patients with advanced chronic renal failure together with preservation of nutritional status. The possible mechanisms by which this effect...
journal_title:Blood purification
pub_type: 临床试验,杂志文章,评审
doi:10.1159/000169557
更新日期:1988-01-01 00:00:00
abstract:AIMS:To improve the side effects caused by sodium citrate (Na(3)Cit), the anticoagulant effects of diethyl citrate (Et(2)Cit) were investigated. METHODS:The in vitro anticoagulant effects and dissociation capacity of the chelate of Et(2)Cit with calcium ions were compared with those of Na(3)Cit in rabbits. RESULTS:Th...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000330891
更新日期:2012-01-01 00:00:00
abstract::The principles and use of plasmapheresis are often little understood by intensivists. We propose to review the principles, the main indications, and the methods of using this technique. ...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000510983
更新日期:2020-10-22 00:00:00
abstract:BACKGROUND:The number of patients receiving renal replacement therapy (RRT) increases annually and worldwide. Differences in the RRT incidence, prevalence, and modality vary between regions and countries for reasons yet to be clarified. AIMS:Gain a better understanding of the association between hemodialysis (HD)-rela...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000368980
更新日期:2015-01-01 00:00:00
abstract::We report the clinical course of 29 patients with Wegener's granulomatosis (WG) treated with plasma exchange (PE) in Norway in the period from 1988 to 1999. Median follow-up was 41.5 months. The mean number of exchanges was 8.5 +/- 5.8 (range 2-32). Median serum creatinine concentration was 400 micromol/l (range 90-1,...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000047004
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND/AIMS:Carpal tunnel syndrome (CTS) is a common clinical presentation of dialysis-related amyloidosis. It was determined whether β(2)-microglobulin (β2M) and advanced glycation end products in serum are predictors of CTS in dialysis patients. METHODS:A total of 385 hemodialysis patients were screened for CTS....
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000338923
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:This study evaluated the mechanism of hemodynamic improvement in polymyxin B-immobilized fiber (PMX) treatment. METHODS:Fifteen septic patients with endotoxemia and/or gram negative infection were treated with PMX. Plasma concentrations of calcitonin gene-related peptide (CGRP) and nitric oxide metabol...
journal_title:Blood purification
pub_type: 临床试验,杂志文章
doi:10.1159/000070696
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:Glycated hemoglobin is used to assess diabetic control although its accuracy in dialysis has been questioned. How does it compare to the Continuous Glucose Monitoring System (CGMS) in peritoneal dialysis (PD) patients? METHODS:We conducted a retrospective analysis of 60 insulin-treated diabetic patients o...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000439242
更新日期:2016-01-01 00:00:00
abstract::Fluid overload may occur in critically ill patients as a result of aggressive resuscitation therapies. In such circumstances, persistent fluid overload must be avoided since it does not benefit the patient while it may be harmful. In the septic patient, early volume expansion seems to be beneficial. Beyond that thresh...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000287776
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Interleukin-10 (IL-10), a potent regulatory monokine produced by activated mononuclear cells, provides an efficient autocrine mechanism for controlling proinflammatory cytokine synthesis. We hypothesized that defective synthesis of IL-10 could contribute to the inflammatory state in hemodialysis (HD) patient...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000066958
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND/AIMS:The objective of this study is to evaluate the relation between sclerostin, arterial stiffness, and cardiovascular events (CVE) in hemodialysis patients (HD). METHODS:Sclerostin level and carotid-femoral pulse wave velocity (PWV) in 97 HD patients and sclerostin level in 40 controls were measured. RES...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000487223
更新日期:2018-01-01 00:00:00
abstract::While acute kidney injury (AKI) has been poorly defined historically, a decade of effort has culminated in a standardized, consensus definition. In parallel, electronic health records (EHRs) have been adopted with greater regularity, clinical informatics approaches have been refined, and the field of EHR-enabled care ...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000458751
更新日期:2017-01-01 00:00:00
abstract::The study was made in vitro of reactions elicited by contact of granulocytes suspended in autologous plasma with three polymers: polyacrylonitrile (AN); polyetherpoly-carbonate (PC), and regenerated cellulose (Cu). Alterations in basal metabolism and biological function of the human blood granulocytes induced by inter...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000170015
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Frequent hemodialysis (HD) may be associated with an increased risk of vascular access complications. Studies addressing vascular access outcomes in frequent HD show conflicting results. METHODS:We searched Medline for trials looking at vascular access outcomes in frequent HD. RESULTS:Nineteen studies met ...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000362106
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Various cytokines are increased in hemodialysis (HD) patients, and are considered prognostic markers. Metabolic acidosis is common among chronic HD patients and is associated with survival. The relationship between acidosis and cytokines in HD patients has not been fully explored. The study aim was to measur...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000346689
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Despite the progression of dialysis techniques, the mortality of hemodialysis (HD) patients is still high in China. Here, a retrospective study was performed to investigate the neglected risk factors of all-cause mortality during maintenance HD (MHD). METHODS:We investigated 117 MHD patients who died betwe...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000497269
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Plastic cannulas have been used to cannulate arteriovenous fistulas (AVFs) for hemodialysis (HD) in Japan for many years. However, the effect of early cannulation with plastic cannulas on AVF patency is not known. OBJECTIVE:We analyzed the relationship between first cannulation time (FCT) and patency rate...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000503678
更新日期:2020-01-01 00:00:00
abstract::We conducted a prospective randomized controlled study to confirm our earlier observation that prolonged subcutaneous implantation of peritoneal catheter reduced peritonitis rate when compared to retrospective data from patients with catheters placed by conventional access technique. A total of 60 patients were random...
journal_title:Blood purification
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000014331
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Calcium (Ca) is an essential element that plays a critical role in many biological processes. In dialysis patients, the regulation of Ca balance is highly complex, given the absence of kidney function, endocrine disturbances and the use of drugs such as phosphate binders, vitamin D analogues, and calcimimeti...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000494584
更新日期:2019-01-01 00:00:00
abstract::Numerous experimental and clinical studies suggest that uric acid might have pathobiologic implications in the development and progression of hypertension, kidney disease, and coronary heart disease, among others, resulting in renewed interest in uric acid as a potential pathogenic mediator in these clinical condition...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000360520
更新日期:2014-01-01 00:00:00
abstract::The recent Kidney Disease Outcomes Quality Initiative (K/DOQI) classification of chronic kidney disease (CKD) includes transplant recipients. Although there are important differences between kidney transplant recipients (KTRs) and patients with native kidney disease, the inclusion of KTRs along with other CKD patients...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000067871
更新日期:2003-01-01 00:00:00
abstract::A group of patients with severe anemia on standard hemodialysis were transferred to polyacrylnitrile hemodiafiltration (HDF), which was arranged in order to obtain an ultrafiltration rate (UF) higher than 100 ml/min. During HDF, despite a significant reduction of the dialysis time, all patients had a significant decre...
journal_title:Blood purification
pub_type: 杂志文章
doi:10.1159/000169591
更新日期:1989-01-01 00:00:00
abstract::During the past few years, it has become increasingly evident that residual renal function (RRF) is an important and independent predictor of poor outcome in patients with chronic kidney disease (CKD). Although the causes of this observation are not fully understood, it appears that the loss of RRF impairs both fluid ...
journal_title:Blood purification
pub_type: 杂志文章,评审
doi:10.1159/000078699
更新日期:2004-01-01 00:00:00