What can we expect from on-line hemodiafiltration?

Abstract:

:On-line hemodiafiltration (ol-HDF) may improve clinical outcome in ESRD. The supposed mechanism is the improved clearance of uremic toxins by convective transport which is added to the diffusion transport. However, recent marked improvement in the performance of dialyzers has allowed higher removal rate of middle to large solutes by diffusion. It is inaccurate to define substances with a higher molecular weight such as uremic toxins. In addition, new methods should be developed for the removal of protein-bound substances. A technical fee for on-line HDF was newly established on the revision of the reimbursement for medical services Japan in 2012 and clearly separated from off-line HDF. As a facility requirement, the calculation of 'addition for maintaining dialysis fluid water quality' was added. Evidence for the clinical effects of ol-HDF have been reported mainly in Europe but is still inaccurate. To confirm the effectiveness of ol-HDF, randomized comparative trials on hemodialysis using super high-flux dialyzers and ol-HDF with same performance hemodiafilter are necessary.

journal_name

Blood Purif

journal_title

Blood purification

authors

Kawanishi H

doi

10.1159/000346217

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

1-5

eissn

0253-5068

issn

1421-9735

pii

000346217

journal_volume

35 Suppl 1

pub_type

杂志文章,评审
  • Proteome patterns in uremic plasma.

    abstract::In patients with chronic kidney disease (CKD), peptides and proteins circulate at altered concentrations versus in healthy individuals. We have characterized proteome samples from 7 pooled CKD stage 5 patients not yet on dialysis and with no known co-morbidities. We also analyzed pooled plasma samples from 7 healthy a...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000178773

    authors: Naseeb U,Shafqat J,Jägerbrink T,Zarina S,Alvestrand A,Jörnvall H,Axelsson J

    更新日期:2008-01-01 00:00:00

  • Is Sclerostin Level Associated with Cardiovascular Diseases in Hemodialysis Patients?

    abstract:BACKGROUND/AIMS:The objective of this study is to evaluate the relation between sclerostin, arterial stiffness, and cardiovascular events (CVE) in hemodialysis patients (HD). METHODS:Sclerostin level and carotid-femoral pulse wave velocity (PWV) in 97 HD patients and sclerostin level in 40 controls were measured. RES...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000487223

    authors: Kundakci Gelir G,Sengul S,Nergizoglu G,Ertürk S,Duman N,Kutlay S

    更新日期:2018-01-01 00:00:00

  • Polymorphonuclear oxygen free radical production and complement activation induced by dialysis membranes as assayed in an experimental model.

    abstract::Activation of polymorphonuclear leukocytes with subsequent production of reactive oxygen metabolites has been reported to occur during hemodialysis related to a membrane bioincompatibility. We used an experimental dialysis model to evaluate, by chemiluminescence, the production of reactive oxygen metabolites and, by C...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000169604

    authors: Cappelli G,Lucchi L,Bonucchi D,Cenci AM,Montagnani G,De Palma M,Lusvarghi E

    更新日期:1989-01-01 00:00:00

  • Peritoneal membrane evaluation in routine clinical practice.

    abstract:BACKGROUND/AIMS:Establishment of reference values for small solute transport, sodium sieving and effluent CA125 with 3.86% (4 h) peritoneal equilibration test (PET), and comparison with fast-fast PET with regard to small solute transport categories. METHODS:Cross-sectional study; 69 prevalent patients. Sodium sieving ...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000113009

    authors: Rodrigues AS,Silva S,Bravo F,Oliveira JC,Fonseca I,Cabrita A,Krediet RT

    更新日期:2007-01-01 00:00:00

  • Fluid overload in critically ill patients with acute kidney injury.

    abstract::Fluid overload may occur in critically ill patients as a result of aggressive resuscitation therapies. In such circumstances, persistent fluid overload must be avoided since it does not benefit the patient while it may be harmful. In the septic patient, early volume expansion seems to be beneficial. Beyond that thresh...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000287776

    authors: Cerda J,Sheinfeld G,Ronco C

    更新日期:2010-01-01 00:00:00

  • Advances and advantages in recent central dialysis fluid delivery system.

    abstract::The central dialysis fluid delivery system (CDDS) has been working exclusively in Japan since 1970, a fact which proves that CDDS is useful in the multi-patient treatment with in-center regular hemodialysis. It is a cost-effective, labor-saving and time-tested system with 40 years of experience. Microbial safety is im...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000213494

    authors: Koda Y,Mineshima M

    更新日期:2009-01-01 00:00:00

  • Defective interleukin-10 synthesis by peripheral blood mononuclear cells among hemodialysis patients.

    abstract:BACKGROUND:Interleukin-10 (IL-10), a potent regulatory monokine produced by activated mononuclear cells, provides an efficient autocrine mechanism for controlling proinflammatory cytokine synthesis. We hypothesized that defective synthesis of IL-10 could contribute to the inflammatory state in hemodialysis (HD) patient...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000066958

    authors: Perianayagam MC,Jaber BL,Guo D,King AJ,Pereira BJ,Balakrishnan VS

    更新日期:2002-01-01 00:00:00

  • Complementary dialysis for daily dialysis.

    abstract::The greatest benefit of PD ist the continuous maintenance of a stable electrolyte and acid-base balance, as well as a continuous solute, sodium and water removal. Moreover, PD is effective in preserving residual renal function (RRF). However, when RRF declines, complications will occur if not compensated for by an inc...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000081871

    authors: Kawanishi H

    更新日期:2004-01-01 00:00:00

  • Assessment of inflow of endotoxin and its fragments in patients on maintenance hemodialysis.

    abstract:BACKGROUND:We estimated the flow of endotoxins (ET) from dialysates into the blood of patients on hemodialysis (HD) using limulus amebocyte lysate (LAL) assays and endotoxin activity (EA) determined by neutrophil respiratory burst activity. METHODS:A cross-sectional study compared groups given ultrapure bicarbonate (n...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000322622

    authors: Suzuki H,Honda H,Kato N,Michihata T,Takahashi K,Shishido K,Akizawa T

    更新日期:2011-01-01 00:00:00

  • Health-Related Quality of Life and Its Factors of Hemodialysis Patients in Suzhou, China.

    abstract:BACKGROUND:To identify factors of health-related quality of life (HRQOL) of Chinese end-stage renal disease patients undergoing hemodialysis (HD). METHODS:In all, 315 HD patients were recruited from a tertiary hospital in Suzhou, -China. Each patient completed the Kidney Disease Quality of Life Short Form. It generate...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章

    doi:10.1159/000485962

    authors: Pan CW,Wu Y,Zhou HJ,Xu BX,Wang P

    更新日期:2018-01-01 00:00:00

  • Membrane-Based Therapeutic Plasma Exchange in Intensive Care.

    abstract::The principles and use of plasmapheresis are often little understood by intensivists. We propose to review the principles, the main indications, and the methods of using this technique. ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000510983

    authors: Redant S,De Bels D,Ismaili K,Honoré PM

    更新日期:2020-10-22 00:00:00

  • Renal replacement therapy in geriatric end-stage renal disease patients: a clinical approach.

    abstract::The number of geriatric patients on dialysis is increasing. This is due to demographic factors, a wider acceptance of elderly patients on dialysis, and an earlier start of dialysis in this patient group. Recent studies have questioned the effect of dialysis on quality of life in elderly patients with severe comorbidit...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000334153

    authors: Kooman JP,Cornelis T,van der Sande FM,Leunissen KM

    更新日期:2012-01-01 00:00:00

  • Dialyzer reprocessing using heat. Scientific and technical considerations.

    abstract::Reprocessing of used dialyzers with chemical disinfectants is practiced commonly in the United States and in some areas of Western Europe. Concern over residual toxic or allergenic agents has encouraged the search for other practical methods to disinfect or sterilize used hemodialyzers. The use of moist heat has been ...

    journal_title:Blood purification

    pub_type:

    doi:10.1159/000170132

    authors: Holmes CJ

    更新日期:1993-01-01 00:00:00

  • New polyether sulfone dialyzers attenuate passage of cytokine-inducing substances from pseudomonas aeruginosa contaminated dialysate.

    abstract::The use of bicarbonate dialysate and high-flux and reprocessed dialyzers has raised concerns about the reverse transfer of dialysate contaminants into the blood compartment. This in vitro study was performed to investigate the reverse transfer of soluble Pseudomonas aeruginosa bacterial products across a polyether sul...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000014336

    authors: Jaber BL,Gonski JA,Cendoroglo M,Balakrishnan VS,Razeghi P,Dinarello CA,Pereira BJ

    更新日期:1998-01-01 00:00:00

  • Organ cross talk in the critically ill: the heart and kidney.

    abstract::Heart failure results in significant morbidity and mortality in the United States. Chronic heart failure is often complicated by renal insufficiency. Further, acute decompensated heart failure is often complicated by worsening renal function or the development of diuretic resistance. Heart failure complicated by renal...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000207198

    authors: Kociol R,Rogers J,Shaw A

    更新日期:2009-01-01 00:00:00

  • Psychological aspects of low protein diet therapy.

    abstract::One of the main problems in low protein diet is patient's noncompliance and the risk of both depression and reduced quality of life. A pilot study investigated the life-style and the state of mood before and during low protein diet. The results show a deterioration in the life-style and the state of mood. Conclusions ...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000169572

    authors: Haeberle KN

    更新日期:1989-01-01 00:00:00

  • Biocompatibility of hemodialysis membranes: a study in healthy subjects.

    abstract::The effect of blood-membrane interaction on several biocompatibility parameters has been investigated. Four groups of healthy subjects underwent sham hemodialysis, i.e. the establishment of blood-dialysis membrane contact, but without circulating dialysate, using cellulose-based membranes (regenerated cellulose and ce...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000170153

    authors: Gutierrez A,Alvestrand A,Bergström J,Beving H,Lantz B,Henderson LW

    更新日期:1994-01-01 00:00:00

  • Effect of the direction of dialysate flow on the efficiency of continuous arteriovenous haemodialysis.

    abstract::We have investigated the effect of the direction of the dialysate flow during continuous arteriovenous haemodialysis. Under similar conditions countercurrent flow was more efficient than concurrent flow in terms of both urea clearance (mean +/- SEM), 23.5 +/- 0.5 compared to 18.4 +/- 0.4 ml/min (p less than 0.001) and...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000169987

    authors: Davenport A,Will EJ,Davison AM

    更新日期:1990-01-01 00:00:00

  • Prevention and management of dialysis catheter complications in the intensive care unit.

    abstract::Dialysis dependence at hospital discharge after acute kidney injury (AKI) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) is found in 10-15% of survivors. In case of severe AKI in the ICU, it is necessary to reconcile two objectives: the creation of an adequate temporary angioaccess for RRT ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000341721

    authors: Wilson P,Lertdumrongluk P,Leray-Moragués H,Chenine-Koualef L,Patrier L,Canaud B

    更新日期:2012-01-01 00:00:00

  • A zebrafish model for uremic toxicity: role of the complement pathway.

    abstract::Many organic solutes accumulate in end-stage renal disease (ESRD) and some are poorly removed with urea-based prescriptions for hemodialysis. However, their toxicities have been difficult to assess. We have employed an animal model, the zebrafish embryo, to test the toxicity of uremic serum compared to control. Serum ...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章

    doi:10.1159/000348456

    authors: Berman N,Lectura M,Thurman J,Reinecke J,Raff AC,Melamed ML,Reinecke J,Quan Z,Evans T,Meyer TW,Hostetter TH

    更新日期:2013-01-01 00:00:00

  • Impact of a genetic polymorphism of the interleukin-1 receptor antagonist on technique survival in peritoneal dialysis patients.

    abstract:BACKGROUND/AIMS:There is a clear association between one allele of the interleukin-1 receptor-antagonist gene (IL-1RN) and inflammatory diseases in which IL-1 is implicated. We evaluated patient survival and technique survival of peritoneal dialysis (PD) patients, while analyzing independent risk factors, in a PD progr...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章

    doi:10.1159/000088988

    authors: Uchiyama K,Naito K,Tsuchida M,Takai K,Okayama N,Fujimura K,Hinoda Y

    更新日期:2005-01-01 00:00:00

  • Access blood flow and the risk of complications in mature forearm and upper arm arteriovenous fistulas.

    abstract:BACKGROUND/AIMS:Optimization of vascular access use in the 'fistula first' era requires comprehension of its clinical behavior. Little is known about mature arteriovenous fistula (AVF) performance and the role of fistula location. Widely used access flow (Qa) was used to analyze complication risks and functionality aft...

    journal_title:Blood purification

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000197561

    authors: Huijbregts HJ,Bots ML,Wittens CH,Schrama YC,Blankestijn PJ

    更新日期:2009-01-01 00:00:00

  • Nocturnal Hemodialysis Compared with Conventional Dialysis for End-Stage Renal Disease Treatment in Polycystic Kidney Disease Patients.

    abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary cause of end-stage renal disease (ESRD). Little is known about outcomes after in-center nocturnal hemodialysis (NHD) treatment in ADPKD patients with ESRD. OBJECTIVES:This study aimed to evaluate the effects of in-center NHD ...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000503679

    authors: Xue C,Sun B,Ye X,Zhou C,Yang B,Zhang L,Yu S

    更新日期:2020-01-01 00:00:00

  • Non-alcoholic fatty liver disease proven by transient elastography in hemodialysis patients: is it a new risk factor for adverse cardiovascular events?

    abstract:BACKGROUND/AIMS:Cardiovascular diseases (CVD) are the leading cause of mortality in hemodialysis (HD) patients. Recently, non-alcoholic fatty liver disease (NAFLD) has been recognized as a new risk factor for adverse CVD events in the general population. Our aim was to analyze the incidence of NAFLD in HD patients by u...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000360270

    authors: Mikolasevic I,Orlic L,Milic S,Zaputovic L,Lukenda V,Racki S

    更新日期:2014-01-01 00:00:00

  • Haemodialysis fluid: composition and clinical importance.

    abstract::Dialysis fluid is produced by the blending of treated water with electrolytes at the patients bed side. Its preparation and composition are important elements of treatment optimisation since many of the constituents play a role in patient well-being. Ideally the composition of the dialysis fluid should match that of p...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000096400

    authors: Hoenich NA,Ronco C

    更新日期:2007-01-01 00:00:00

  • Regional Citrate Anticoagulation versus No-Anticoagulation for Continuous Venovenous Hemofiltration in Acute Severe Hypernatremia Patients with Increased Bleeding Risk: A Retrospective Cohort Study.

    abstract:PURPOSE:This study was aimed at evaluating the efficacy and safety of regional citrate anticoagulation (RCA) versus no-anticoagulation continuous venovenous hemofiltration (CVVH) in acute severe hypernatremia patients with increased bleeding risk. MATERIALS AND METHODS:Acute severe hypernatremia patients with high ble...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章

    doi:10.1159/000502937

    authors: Zhao L,Ma F,Yu Y,Li Y,Wang Y,He L,Zhou M,Tian X,Jing R,Li L,Li L,Huang C,Bai M,Sun S

    更新日期:2020-01-01 00:00:00

  • Cytokine secretion and markers of inflammation in relation to acidosis among chronic hemodialysis patients.

    abstract:BACKGROUND:Various cytokines are increased in hemodialysis (HD) patients, and are considered prognostic markers. Metabolic acidosis is common among chronic HD patients and is associated with survival. The relationship between acidosis and cytokines in HD patients has not been fully explored. The study aim was to measur...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000346689

    authors: Ori Y,Bergman M,Bessler H,Zingerman B,Levy-Drummer RS,Gafter U,Salman H

    更新日期:2013-01-01 00:00:00

  • Enhanced biocompatibility with a new cellulosic membrane: Cuprophan versus Hemophan.

    abstract::Recently, a new type of modified cellulosic membrane (Hemophan) has been made available for the first clinical trials. In contrast to cellulose acetate membranes only about 5% of the hydroxyl groups of cellulose are substituted by tertiary amino groups. Objective of the present study was to assess the compatibility pe...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000169475

    authors: Schaefer RM,Hörl WH,Kokot K,Heidland A

    更新日期:1987-01-01 00:00:00

  • Erythropoietin-induced changes in protein nutrition: quantitative assessment by urea kinetic modeling analysis.

    abstract::To evaluate objectively the effects of recombinant human erythropoietin (rHuEPO) administration on nutritional status in stable dialyzed patients, we used urea kinetic modeling (UKM) analysis and dietary protein intake evaluation by dietary assessment. Fifteen patients (9 females, 6 males; mean age 46.9 +/- 15.6 years...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000169982

    authors: Canaud B,Bouloux C,Rivory JP,Taib J,Garred LJ,Florence P,Mion C

    更新日期:1990-01-01 00:00:00

  • Current Focuses in Serum Lipid Abnormalities in Dialysis Patients.

    abstract:BACKGROUND:Dyslipidemia is a common metabolic complication in patients with chronic kidney disease and is detected as changes in lipoprotein concentrations in serum. SUMMARY:Recently, other features of lipid abnormalities have been described, such as alterations in serum n-3 polyunsaturated fatty acids, cholesterol me...

    journal_title:Blood purification

    pub_type: 评论,杂志文章

    doi:10.1159/000441581

    authors: Shoji T

    更新日期:2015-01-01 00:00:00