Kidney transplantation improves sleep-related breathing in hemodialysis patients.

Abstract:

AIMS:To assess whether kidney transplantation improves sleep-related breathing disorders associated with hemodialysis. METHODS:A prospective study was carried out using full-night polysomnography. Nine hemodialysis patients (7 men and 2 women, aged 42 +/- 16.2 years, BMI 26 +/- 3.7) who later received a successful kidney transplantation were evaluated. Main sleep quality and respiratory variables were recorded: number of dips in oxygen saturation (SaO(2)) > or =3% per hour of sleep; percentage of sleep time with SaO(2) <90%; percentage of sleep time in apnea and hypopnea, and sleep apnea/hypopnea index (AHI). RESULTS:After kidney transplantation, the AHI improved in 8 of the 9 patients (10 +/- 10.7 vs. 4.9 +/- 6.1, p = 0.029). A decrease in the percentage of sleep time in apnea/hypopnea (5 +/- 6.8 vs. 0.7 +/- 1.1%, p = 0.008) and a reduction in the number of desaturations (25 +/- 26 vs. 12 +/- 11.2%, p = 0.010) were observed. CONCLUSIONS:Kidney transplantation improved respiratory events and nocturnal SaO(2) in hemodialysis patients.

journal_name

Blood Purif

journal_title

Blood purification

authors

Jurado-Gámez B,Martin-Malo A,Rodriguez-Benot A,Muñoz-Cabrera L,Cosano Povedano A,Aljama P

doi

10.1159/000157373

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

485-90

issue

6

eissn

0253-5068

issn

1421-9735

pii

000157373

journal_volume

26

pub_type

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